PubRank

E M Rubin

Author PubWeight™ 155.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 VISTA : visualizing global DNA sequence alignments of arbitrary length. Bioinformatics 2000 12.50
2 Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992 10.97
3 Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science 2000 10.14
4 An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001 8.73
5 Active conservation of noncoding sequences revealed by three-way species comparisons. Genome Res 2000 6.18
6 Genomic strategies to identify mammalian regulatory sequences. Nat Rev Genet 2001 5.78
7 Microarray expression profiling identifies genes with altered expression in HDL-deficient mice. Genome Res 2000 4.95
8 Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease. Science 1997 4.25
9 Detection of sickle cell anaemia and thalassaemias. Nature 1987 3.94
10 Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J Lipid Res 1995 3.73
11 A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron 1999 3.50
12 Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing. Proc Natl Acad Sci U S A 2009 3.16
13 Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome. Nat Genet 1997 2.81
14 Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat Immunol 2001 2.62
15 Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. Proc Natl Acad Sci U S A 1998 2.32
16 Atherogenesis in transgenic mice expressing human apolipoprotein(a) Nature 1992 2.28
17 Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J Clin Invest 1994 1.93
18 Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. J Biol Chem 1999 1.85
19 Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy. Proc Natl Acad Sci U S A 2000 1.82
20 Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res 1997 1.69
21 Protein composition determines the anti-atherogenic properties of HDL in transgenic mice. Nature 1993 1.62
22 Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics. J Biol Chem 2000 1.52
23 Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. Proc Natl Acad Sci U S A 1994 1.42
24 The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression. Neuron 1997 1.32
25 Induction of the early growth response (Egr) family of transcription factors during thymic selection. J Exp Med 1997 1.28
26 Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue. Nat Genet 1995 1.27
27 Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. Proc Natl Acad Sci U S A 2000 1.26
28 Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatr Res 2000 1.26
29 Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic mice. J Lipid Res 1994 1.22
30 Disruption of the murine lecithin:cholesterol acyltransferase gene causes impairment of adrenal lipid delivery and up-regulation of scavenger receptor class B type I. J Biol Chem 1997 1.19
31 Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype. Hum Mol Genet 1996 1.17
32 In vivo demonstration of red cell-endothelial interaction, sickling and altered microvascular response to oxygen in the sickle transgenic mouse. J Clin Invest 1995 1.15
33 Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. Proc Natl Acad Sci U S A 1996 1.13
34 A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. Blood 1995 1.12
35 Expression of thymidylate synthetase activity in Bacillus subtilis upon integration of a cloned gene from Escherichia coli. Gene 1980 1.10
36 The apolipoprotein(a) gene is regulated by sex hormones and acute-phase inducers in YAC transgenic mice. Nat Genet 1995 1.09
37 Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a). J Clin Invest 1995 1.08
38 Regulation and activity of the human ABCA1 gene in transgenic mice. J Biol Chem 2001 1.04
39 Modification of apolipoprotein(a) lysine binding site reduces atherosclerosis in transgenic mice. J Clin Invest 1997 1.02
40 ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice. J Lipid Res 1998 1.01
41 Effect of high-frequency oral airway and chest wall oscillation and conventional chest physical therapy on expectoration in patients with stable cystic fibrosis. Chest 1998 1.01
42 A simple and efficient method for making site-directed mutants, deletions, and fusions of large DNA such as P1 and BAC clones. Genome Res 1996 0.99
43 Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice. J Biol Chem 1992 0.98
44 Faithful expression of the human 5q31 cytokine cluster in transgenic mice. J Immunol 2000 0.95
45 Functional screening and complex traits: human 21q22.2 sequences affecting learning in mice. Hum Mol Genet 1997 0.95
46 Survival of a hydropic infant with homozygous alpha-thalassemia-1. J Pediatr 1986 0.95
47 Feedback mechanism of focal vascular lesion formation in transgenic apolipoprotein(a) mice. J Biol Chem 1996 0.94
48 Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2. Genomics 1995 0.94
49 Expression of human lecithin-cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein AI and human apolipoprotein all on plasma lipoprotein cholesterol metabolism. J Clin Invest 1995 0.93
50 Developmental regulation of the human zeta globin gene in transgenic mice. Nucleic Acids Res 1990 0.92
51 Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation 1999 0.90
52 Lipoprotein(a) vascular accumulation in mice. In vivo analysis of the role of lysine binding sites using recombinant adenovirus. J Clin Invest 1997 0.90
53 HDL deficiency in genetically engineered mice requires elevated LDL to accelerate atherogenesis. Arterioscler Thromb Vasc Biol 1997 0.89
54 Neurobehavioral deficits in mice lacking the erythrocyte membrane cytoskeletal protein 4.1. Curr Biol 1998 0.89
55 Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration. J Lipid Res 1999 0.87
56 Genomic interval engineering of mice identifies a novel modulator of triglyceride production. Proc Natl Acad Sci U S A 2000 0.87
57 Gene transfer of cytidine deaminase apoBEC-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbits. Hum Gene Ther 1996 0.86
58 Analysis of the human zeta-globin gene promoter in transgenic mice. Blood 1993 0.86
59 A transgenic mouse model of hemoglobin S Antilles disease. Blood 1997 0.86
60 A simple sensitive prenatal test for hydrops fetalis caused by alpha-thalassaemia. Lancet 1985 0.85
61 The mouse as a model for human cardiovascular disease and hyperlipidemia. Curr Opin Lipidol 1994 0.85
62 Selective uptake of HDL cholesteryl esters is active in transgenic mice expressing human apolipoprotein A-I. J Lipid Res 1995 0.84
63 High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice. J Lipid Res 1997 0.83
64 Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-I(Milano). Atherosclerosis 1998 0.83
65 Contrasting in vivo effects of murine and human apolipoprotein A-II. Role of monomer versus dimer. J Biol Chem 1996 0.82
66 A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice. Proc Natl Acad Sci U S A 1996 0.82
67 Single base, site-directed mutagenesis of a 90 kilobase-pair P1 clone. Nucleic Acids Res 1994 0.81
68 The properties of HDL in genetically engineered mice. Curr Opin Lipidol 1994 0.80
69 A method for the preparative isolation and concentration of intact yeast artificial chromosomes. Nucleic Acids Res 1989 0.80
70 Site-specific mutagenesis demonstrates that cysteine 4326 of apolipoprotein B is required for covalent linkage with apolipoprotein (a) in vivo. J Biol Chem 1995 0.79
71 Atherogenesis Insights from the study of transgenic and gene-targeted mice. Trends Cardiovasc Med 2011 0.79
72 Apolipoprotein(a) yeast artificial chromosome transgenic rabbits. Lipoprotein(a) assembly with human and rabbit apolipoprotein B. J Biol Chem 1998 0.79
73 Cholesterol efflux, lecithin-cholesterol acyltransferase activity, and pre-beta particle formation by serum from human apolipoprotein A-I and apolipoprotein A-I/apolipoprotein A-II transgenic mice consistent with the latter being less effective for reverse cholesterol transport. Biochemistry 1997 0.79
74 Functional screening of an asthma QTL in YAC transgenic mice. Nat Genet 1999 0.79
75 Evidence that apolipoprotein A-IMilano has reduced capacity, compared with wild-type apolipoprotein A-I, to recruit membrane cholesterol. Arterioscler Thromb Vasc Biol 1997 0.78
76 Rapid genotyping of mice with hemoglobinopathies and globin transgenes. Biochem Genet 1998 0.78
77 A common phenotype associated with atherogenesis in diverse mouse models of vascular lipid lesions. J Vasc Res 2001 0.77
78 Selective erythroid replacement in murine beta-thalassemia using fetal hematopoietic stem cells. Proc Natl Acad Sci U S A 1993 0.77
79 A role for Ras signaling in coreceptor regulation during differentiation of a double-positive thymocyte cell line. J Immunol 1997 0.77
80 Magnetic resonance evidence of hypoxia in a homozygous alpha-knockout of a transgenic mouse model for sickle cell disease. J Clin Invest 1996 0.77
81 Effect of human apoE4 on the clearance of chylomicron-like lipid emulsions and atherogenesis in transgenic mice. Arterioscler Thromb 1994 0.76
82 Deletion of amino acids Glu146-->Arg160 in human apolipoprotein A-I (ApoA-ISeattle) alters lecithin:cholesterol acyltransferase activity and recruitment of cell phospholipid. Biochemistry 1998 0.76
83 Human-mouse comparative genomics: successes and failures to reveal functional regions of the human genome. Cold Spring Harb Symp Quant Biol 2003 0.76
84 Apolipoprotein AI expression and high density lipoprotein distribution in transgenic mice during development. J Biol Chem 1992 0.76
85 Structural and functional properties of human and mouse apolipoprotein A-I. Biochim Biophys Acta 1994 0.75
86 The geneticist's grail. West J Med 1987 0.75
87 Vascular accumulation of Lp(a): in vivo analysis of the role of lysine-binding sites using recombinant adenovirus. Clin Genet 1997 0.75
88 Database searches for binding sites. Science 2000 0.75
89 Unilateral pulmonary hyperinflation from mucus check-valve mechanism. Crit Care Med 1986 0.75
90 Sickle cell trait/hereditary persistence of fetal hemoglobin trait. Misdiagnosis as sickle cell anemia by newborn screening. Am J Dis Child 1979 0.75
91 Premature termination of treatment among alcoholics: predicting outpatient clinic dropouts. Curr Alcohol 1981 0.75
92 Human apo A-I in transgenic mice is more efficient in activating lecithin:cholesterol acyltransferase than mouse apo A-I. Biochim Biophys Acta 1995 0.75
93 Genome scan identifies a locus affecting gamma-globin level in human beta-cluster YAC transgenic mice. Mamm Genome 2000 0.75
94 Cholesteryl ester transfer protein and atherogenesis. Ann N Y Acad Sci 1997 0.75