Published in Brain Res on March 23, 1998
Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window. Br J Pharmacol (2002) 1.06
Effects of maternal treatment with corticosteroids on tight junction protein expression in the cerebral cortex of the ovine fetus with and without exposure to in utero brain ischemia. Brain Res (2007) 0.87
Docosahexaenoic acid improves behavior and attenuates blood-brain barrier injury induced by focal cerebral ischemia in rats. Exp Transl Stroke Med (2015) 0.83
Ischemia-induced increase in microvascular phosphodiesterase 4D expression in rat hippocampus associated with blood brain barrier permeability: effect of age. ACS Chem Neurosci (2012) 0.81
Permeability Parameters Measured with Dynamic Contrast-Enhanced MRI: Correlation with the Extravasation of Evans Blue in a Rat Model of Transient Cerebral Ischemia. Korean J Radiol (2015) 0.78
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature (1995) 13.80
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell (1997) 10.52
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature (1995) 6.62
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry (2011) 4.91
The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. EMBO J (1996) 4.55
Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage. Br Med J (Clin Res Ed) (1985) 4.30
Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature (1996) 3.79
Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol (1985) 3.63
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun (1997) 3.61
Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke (1996) 3.16
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron (1995) 3.11
Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab (1987) 3.04
Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97
Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev (1999) 2.90
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol (1996) 2.80
Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production. Eur J Immunol (1996) 2.67
Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Res (1996) 2.60
Purification and characterization of the human interleukin-18 receptor. J Biol Chem (1997) 2.58
Takayasu's arteritis. Clinical report of eighty-four cases and immunological studies of seven cases. Circulation (1967) 2.42
New mutations fts-36, lts-33, and ftsW clustered in the mra region of the Escherichia coli chromosome induce thermosensitive cell growth and division. J Bacteriol (1989) 2.41
IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol (1997) 2.29
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry (2010) 2.21
Hippuric acid, phenol, and trichloroacetic acid levels in the urine of Japanese subjects with no known exposure to organic solvents. Br J Ind Med (1969) 2.18
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke (2001) 2.16
Effect of adrenergic-blocking or -stimulating agents on plasma growth hormone, immunoreactive insulin, and blood free fatty acid levels in man. J Clin Invest (1971) 2.15
Year one dental visit. Pediatr Dent (2001) 2.14
Fractal analysis of cerebral blood flow distribution in Alzheimer's disease. J Nucl Med (2001) 2.08
Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke (1989) 2.00
Amphetamine intoxication with coagulopathy, hyperthermia, and reversible renal failure. A syndrome resembling heatstroke. Ann Intern Med (1970) 1.99
Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors. EMBO J (1999) 1.94
Experimental carbon monoxide encephalopathy in the primate I. Physiologic and metabolic aspects. Arch Neurol (1974) 1.90
An experimental study of a combination method using a pedicle screw and laminar hook for the osteoporotic spine. Spine (Phila Pa 1976) (1997) 1.88
Rodent models of cerebral ischemia. Stroke (1989) 1.83
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia. J Neurochem (1995) 1.82
Insulin secretion and insulin sensitivity at different stages of glucose tolerance: a cross-sectional study of Japanese type 2 diabetes. Metabolism (2004) 1.82
Combating hyperthermia in acute stroke: a significant clinical concern. Stroke (1998) 1.79
Significance of urinary hippuric acid determination as an index of toluene exposure. Br J Ind Med (1969) 1.77
Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. JAMA (1998) 1.76
Acetylcholine receptor clustering and nuclear movement in muscle fibers in culture. J Cell Biol (1987) 1.74
Cloning of a pH-sensitive K+ channel possessing two transmembrane segments. Nature (1994) 1.73
Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells. J Cell Biol (1984) 1.70
Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. Proc Natl Acad Sci U S A (1998) 1.70
Diffusion-weighted magnetic resonance imaging confirms marked neuroprotective efficacy of albumin therapy in focal cerebral ischemia. Stroke (1998) 1.69
Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin. Br J Cancer (2004) 1.67
A method for determination of trichloroethanol and trichloroacetic acid in urine. Br J Ind Med (1968) 1.65
The polymorphism in the caudal-related homeodomain protein Cdx-2 binding element in the human vitamin D receptor gene. J Bone Miner Res (2001) 1.62
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J Neurosci (1998) 1.61
Evidence that tyrosine phosphorylation may increase tight junction permeability. J Cell Sci (1995) 1.60
Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons. J Neurosci (1998) 1.60
Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats. J Cereb Blood Flow Metab (1993) 1.59
A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant. Appl Microbiol Biotechnol (2002) 1.58
Phase II study of S-1 in patients with advanced biliary tract cancer. Br J Cancer (2004) 1.58
Newly identified genes involved in the signal transduction of Escherichia coli K-12. Gene (1994) 1.56
Influence of alcohol intake, cigarette smoking, and occupational status on idiopathic osteonecrosis of the femoral head. Clin Orthop Relat Res (1988) 1.54
Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J Cell Biol (1997) 1.52
(S)-emopamil, a novel calcium channel blocker and serotonin S2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat. Neurology (1988) 1.52
Quantitative evaluation of vimentin expression in tumour stroma of colorectal cancer. Br J Cancer (2007) 1.50
Long-term peritoneal dialysis is a risk factor of sclerosing encapsulating peritonitis for children. Perit Dial Int (2001) 1.50
Evaluation of preserved urinary red blood cells by light microscopy. Clin Nephrol (1997) 1.48
A new agglutination test for serum antibodies to adult T-cell leukemia virus. Gan (1984) 1.48
p120, a p120-related protein (p100), and the cadherin/catenin complex. J Cell Biol (1995) 1.48
Common variable immunodeficiency: how many diseases? Immunol Today (1997) 1.48
Clinical evaluation of irreversible image compression: analysis of chest imaging with computed radiography. Radiology (1990) 1.47
Three markers of adult non-myelin-forming Schwann cells, 217c(Ran-1), A5E3 and GFAP: development and regulation by neuron-Schwann cell interactions. Development (1990) 1.47
Pigmented squamous cell carcinoma of the scrotum associated with a lentigo. Br J Dermatol (1999) 1.46
Blocking cytochrome c activity within intact neurons inhibits apoptosis. J Cell Biol (1998) 1.45
Protein aggregation after focal brain ischemia and reperfusion. J Cereb Blood Flow Metab (2001) 1.45
A review of the effects of exercise on appetite regulation: an obesity perspective. Int J Obes (Lond) (2008) 1.45
Experimental carbon monoxide encephalopathy in the primate. II. Clinical aspects, neuropathology, and physiologic correlation. Arch Neurol (1974) 1.44
Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes. J Biol Chem (1996) 1.44
The use of antisense mRNA to inhibit the tonoplast H+ ATPase in carrot. Plant Cell (1992) 1.43
Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F. Oncogene (1998) 1.42
Transitional mucosa in human colorectal lesions. Dis Colon Rectum (1990) 1.42
CSF tau protein: a new prognostic marker for Guillain-Barré syndrome. Neurology (2006) 1.40
Does resuscitative hypothermia protect the ischemic brain? Crit Care Med (1993) 1.40
Effect of low concentration of epinephrine on human platelet aggregation analyzed by particle counting method and confocal microscopy. J Lab Clin Med (1997) 1.39
Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F. Oncogene (1999) 1.39
Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons. Mol Cell Biol (2000) 1.39
Interleukin 6 stimulates growth of vascular smooth muscle cells in a PDGF-dependent manner. Am J Physiol (1991) 1.39
Turner syndrome and ganglioneuroma. J Pediatr Hematol Oncol (2000) 1.38
The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. J Neuropathol Exp Neurol (1990) 1.38
Retrosplenial cortex (BA 29/30) hypometabolism in mild cognitive impairment (prodromal Alzheimer's disease). Eur J Neurosci (2003) 1.36
Clock genes outside the suprachiasmatic nucleus involved in manifestation of locomotor activity rhythm in rats. Eur J Neurosci (2000) 1.36
Highly bright X-ray generator using heat of fusion with a specially designed rotating anticathode. J Synchrotron Radiat (2008) 1.36
Black widow spider venom: effect of purified toxin on lipid bilayer membranes. Science (1976) 1.36
Double mode of action of black widow spider venom on frog neuromuscular junction. J Neurocytol (1978) 1.36
Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus. Biochem Biophys Res Commun (1998) 1.36
Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells. J Immunol (2001) 1.35
A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. Br J Cancer (2007) 1.34
Gardnerella vaginalis in prepubertal girls. Am J Dis Child (1987) 1.34
Urinary t,t-muconic acid as an indicator of exposure to benzene. Br J Ind Med (1989) 1.34
Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci Lett (1989) 1.33