PubRank

A M Saunders

Author PubWeight™ 206.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993 33.32
2 Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993 15.04
3 Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet 1994 7.07
4 Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med 2000 6.72
5 Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 1998 5.93
6 Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci U S A 1993 5.68
7 Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci U S A 1993 4.86
8 Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 2000 4.85
9 Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. JAMA 1997 4.00
10 Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J 2006 3.92
11 Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. N Engl J Med 1998 3.23
12 Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals. J Neuropathol Exp Neurol 1998 2.92
13 A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. Pharmacogenomics J 2009 2.66
14 ApoE genotype and survival from intracerebral haemorrhage. Lancet 1995 2.07
15 An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nat Genet 1999 2.01
16 Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol 1994 1.84
17 Identification of novel genes in late-onset Alzheimer's disease. Exp Gerontol 2000 1.74
18 Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci U S A 1994 1.74
19 Clinical application of apolipoprotein E genotyping to Alzheimer's disease. Lancet 1994 1.71
20 Flow cytometric analysis of lymphocyte phenotypes in AIDS using monoclonal antibodies and simultaneous dual immunofluorescence. Clin Immunol Immunopathol 1986 1.68
21 Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs. Neurobiol Aging 1996 1.65
22 Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease. Stroke 1993 1.63
23 There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease. Arch Neurol 1995 1.51
24 Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. Ann Thorac Surg 1997 1.48
25 Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition. Neurology 1997 1.47
26 No genetic effect of alpha1-antichymotrypsin in Alzheimer disease. Genomics 1996 1.45
27 Smoking, Alzheimer's disease, and confounding with genes. Lancet 1995 1.43
28 Apolipoprotein E in Creutzfeldt-Jacob disease. Lancet 1995 1.41
29 ApoE, Alzheimer's disease, and recovery from brain stress. Ann N Y Acad Sci 1997 1.40
30 Analysis of association at single nucleotide polymorphisms in the APOE region. Genomics 2000 1.40
31 A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biol Psychiatry 1997 1.39
32 Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiol Dis 1996 1.35
33 APOE is a major susceptibility gene for Alzheimer's disease. Curr Opin Biotechnol 1994 1.33
34 The Hemalog D white cell differential system. J Histochem Cytochem 1974 1.32
35 Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender. Mol Vis 2000 1.31
36 Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance. Arch Neurol 1995 1.27
37 Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. Am J Hum Genet 2000 1.26
38 Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype. Neurology 1997 1.24
39 Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. J Neuropathol Exp Neurol 1994 1.22
40 Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937). Differentiation 1998 1.22
41 Using genetics to enable studies on the prevention of Alzheimer's disease. Clin Pharmacol Ther 2012 1.14
42 Sequestration of amyloid beta-peptide. Ann N Y Acad Sci 1993 1.13
43 Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology 1999 1.13
44 Corticosteroids in the treatment of Engelmann's disease: progressive diaphyseal dysplasia. Pediatrics 1970 1.11
45 Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele. Am J Psychiatry 1999 1.11
46 Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology 1996 1.10
47 Characterization of murine carcinoembryonic antigen gene family members. Mamm Genome 1992 1.09
48 Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Exp Neurol 1994 1.09
49 Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology 1995 1.08
50 Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease). Pharmacogenomics J 2006 1.08
51 Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study. J Neurol Sci 2001 1.06
52 Further evidence linking late-onset Alzheimer disease with chromosome 12. JAMA 1999 1.05
53 Complete genomic screen in late-onset familial Alzheimer's disease. Neurobiol Aging 1998 1.02
54 Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Ann Neurol 1997 1.01
55 APOE-epsilon4 predicts incident AD in Japanese-American men: the honolulu-asia aging study. Neurology 2000 1.01
56 The relationship of APOE genotype to cognitive functioning in older African-American and Caucasian community residents. J Am Geriatr Soc 2001 1.00
57 Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation. Acta Neuropathol 2000 1.00
58 Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years. Alzheimer Dis Assoc Disord 1998 0.99
59 Alzheimer's disease and apolipoprotein E-4 allele in an Amish population. Ann Neurol 1996 0.94
60 A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. Pharmacogenomics J 2004 0.94
61 Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. Neuromuscul Disord 2013 0.92
62 Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies. Curr Alzheimer Res 2011 0.92
63 No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics 1998 0.91
64 The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. JAMA 1995 0.91
65 Dementia with Lewy bodies and Alzheimer's disease. Acta Neuropathol 2001 0.90
66 Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients. Anesthesiology 2000 0.88
67 Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study. J Gerontol B Psychol Sci Soc Sci 2000 0.88
68 Evaluation of biologic sources of variation of leukocyte counts and other hematologic quantities using very precise automated analyzers. Am J Clin Pathol 1978 0.88
69 Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Ann N Y Acad Sci 1996 0.88
70 Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease. Arzneimittelforschung 1995 0.88
71 A new technique for making häutchen preparations of unfixed aortic endothelium. J Atheroscler Res 1968 0.87
72 Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neurosci Lett 1994 0.86
73 Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiol Aging 1998 0.85
74 Pathologic findings in a case of cardiac transplantation. JAMA 1968 0.85
75 Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. J Cereb Blood Flow Metab 1998 0.85
76 Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy. Ann Neurol 1996 0.85
77 Within-day physiologic variation of leukocyte types in healthy subjects as assayed by two automated leukocyte differential analyzers. Am J Clin Pathol 1981 0.85
78 Relation of age and apolipoprotein E to cognitive function in Down syndrome adults. Neuroreport 1997 0.84
79 Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations. FEBS Lett 1997 0.84
80 ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neurosci Lett 1995 0.84
81 Sources of physiological variation in differential leukocyte counting. Blood Cells 1985 0.84
82 APOE genotype is a risk factor for neuropathy severity in diabetic patients. Neurology 2003 0.83
83 A proximal mouse chromosome 9 linkage map that further defines linkage groups homologous with segments of human chromosomes 11, 15, and 19. Genomics 1991 0.83
84 The beta-phosphoro[35S]thioate analogue of UDP-Glc is efficiently utilized by the glucose phosphotransferase and is relatively resistant to hydrolytic degradation. Biochim Biophys Acta 1987 0.83
85 Genotypes and phenotypes for apolipoprotein E and Alzheimer disease in the Honolulu-Asia aging study. Clin Chem 2000 0.83
86 Apolipoprotein E genotype and Lewy body disease. Neurology 1995 0.83
87 Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. Ann Neurol 1997 0.82
88 Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging. Ann N Y Acad Sci 1996 0.82
89 Apolipoprotein E E4 allele and risk of dementia. JAMA 1995 0.82
90 Enhanced biological phosphorus removal in a sequencing batch reactor using propionate as the sole carbon source. Biotechnol Bioeng 2004 0.81
91 Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K). Neurosci Lett 1999 0.81
92 No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics 1999 0.81
93 Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons. Neurobiol Dis 1998 0.81
94 The Microbial Database for Danish wastewater treatment plants with nutrient removal (MiDas-DK) - a tool for understanding activated sludge population dynamics and community stability. Water Sci Technol 2013 0.80
95 Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. Neurogenetics 1998 0.80
96 Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology. J Neuropathol Exp Neurol 1998 0.79
97 Apolipoprotein E polymorphisms and age at first coronary artery bypass graft. Anesth Analg 2001 0.79
98 Cytofluorometric study of mast cell polyanions. I. Instrumentation and ion-exchange bead standards. Anal Biochem 1968 0.79
99 Apolipoprotein E genotyping as a diagnostic adjunct for Alzheimer's disease. Int Psychogeriatr 1997 0.79
100 Histochemical nomenclature of carbohydrate-rich components. J Histochem Cytochem 1966 0.78
101 No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genet Epidemiol 1997 0.78
102 Development of automation of differential leukocyte counts by use of cytochemistry. Clin Chem 1972 0.78
103 Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. Brain Res Mol Brain Res 1998 0.78
104 Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases. Cold Spring Harb Symp Quant Biol 1996 0.78
105 D2 dopamine receptor A1 allele in Alzheimer disease and aging. Arch Neurol 1997 0.78
106 A new immune monitoring system for the determination of lymphoid cell subsets. Ann N Y Acad Sci 1986 0.78
107 On the histochemical nomenclature for sialomucins. J Histochem Cytochem 1966 0.77
108 Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Ann Neurol 1998 0.77
109 A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19. Genomics 1991 0.76
110 Evaluation of suspected dementia. N Engl J Med 1996 0.76
111 Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease. Ann Neurol 1996 0.76
112 A rapid spot test for urinary methylmalonic acid collected on ion-exchange filter paper. Clin Chim Acta 1983 0.76
113 No association between alpha 1-antichymotrypsin and familial Alzheimer's disease. Ann N Y Acad Sci 1996 0.76
114 Cytofluorometric study of mast cell polyanions. II. Adult rat peritoneal mast cells regenerating after polymyxin treatment. J Histochem Cytochem 1969 0.76
115 Apolipoprotein E alleles in childhood-onset schizophrenia. Am J Med Genet 1999 0.76
116 Apolipoprotein E uptake and low-density lipoprotein receptor-related protein expression by the NTera2/D1 cell line: a cell culture model of relevance for late-onset Alzheimer's disease. Neurobiol Dis 1997 0.75
117 Cryptococcosis: survival attributed to combination antifungal treatment. Br Med J 1978 0.75
118 Clinical overdiagnosis of vascular dementia versus necropsy confirmed series. J Neurol Neurosurg Psychiatry 1997 0.75
119 Glycosylated hemoglobin as a diagnostic test for type 2 diabetes mellitus. JAMA 2000 0.75
120 No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians. Neurosci Lett 1996 0.75
121 Mixed malignant tumour of the lung. Thorax 1979 0.75
122 On reviewing glycoconjugates. J Histochem Cytochem 1992 0.75
123 Prediction for unimpaired subjects is different from diagnosis of demented patients. Ann Neurol 1997 0.75
124 Hematologic automation by use of continuous flow systems. J Histochem Cytochem 1974 0.75
125 Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation. Biochem Pharmacol 1999 0.75
126 The presentation of three-dimensional reconstructions from serial sections. J Microsc 1976 0.75
127 The automation of cytochemical methods for automated cytophotometers. J Histochem Cytochem 1977 0.75
128 White blood cells: what to do beyond measurement. Blood Cells 1980 0.75
129 Studies on pinnipeds. 1. Obstructive emphysema in an elephant seal (Mirounga angustirostris). Lab Anim Care 1966 0.75
130 Mouse chromosome 7. Mamm Genome 1991 0.75
131 Apolipoprotein E4 (epsilon) allele does not affect the onset or symptom severity in progressive supranuclear palsy. Arch Neurol 1998 0.75
132 Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy? Epilepsia 1994 0.75
133 Electron microscopy of chondromucoprotein and the products of its digestion with hyaluronidase and papain. Nature 1967 0.75
134 Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement. Blood 1985 0.75
135 No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients. Neurosci Lett 1998 0.75
136 Absorption and fluorescence spectra of euchrysine GGNX and acridine orange; effects of heparin, NaCl and a cation exchange resin. Stain Technol 1968 0.75
137 Renal cortical necrosis with pituitary infarction in a nonpregnant woman. Arch Pathol 1968 0.75