Published in Br J Ophthalmol on May 01, 1976
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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest (2007) 3.39
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Increased expression of angiogenic growth factors in age-related maculopathy. Br J Ophthalmol (1997) 2.28
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Histologic basis of variations in retinal pigment epithelium autofluorescence in eyes with geographic atrophy. Ophthalmology (2013) 1.43
Choroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjects. Int Ophthalmol (2014) 1.43
CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med (2013) 1.42
Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration. J Lipid Res (2009) 1.41
Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. PLoS One (2008) 1.40
Clinico-morphologic correlations of drusen of Bruch's membrane. Trans Am Ophthalmol Soc (1980) 1.40
Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Retin Eye Res (2010) 1.39
Animal models of age related macular degeneration. Mol Aspects Med (2012) 1.39
Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function. EMBO J (2003) 1.34
Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration. Proc Natl Acad Sci U S A (2011) 1.30
Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29
The association between statin use and age related maculopathy. Br J Ophthalmol (2003) 1.28
Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration. Vision Res (2009) 1.28
Cholesterol in the retina: the best is yet to come. Prog Retin Eye Res (2014) 1.27
Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy. Exp Eye Res (2011) 1.25
Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy. Invest Ophthalmol Vis Sci (2008) 1.24
Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration. Am J Pathol (2011) 1.22
Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model. Biomed Opt Express (2011) 1.22
The expression of advanced glycation endproduct receptors in rpe cells associated with basal deposits in human maculas. Exp Eye Res (2005) 1.21
Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study. Br J Ophthalmol (1993) 1.19
Bruch's membrane change with age. Br J Ophthalmol (1992) 1.19
Age and disease-related structural changes in the retinal pigment epithelium. Clin Ophthalmol (2008) 1.19
CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration. J Neuroinflammation (2010) 1.18
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Invest Ophthalmol Vis Sci (2011) 1.18
Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study. JAMA Ophthalmol (2014) 1.17
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Prog Retin Eye Res (2014) 1.17
Lipoprotein particles of intraocular origin in human Bruch membrane: an unusual lipid profile. Invest Ophthalmol Vis Sci (2008) 1.16
DETECTION OF NONEXUDATIVE CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. Retina (2015) 1.15
Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch. Exp Eye Res (2007) 1.14
Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice. Ophthalmic Res (2008) 1.14
Ocular fundus auto-fluorescence observations at different wavelengths in patients with age-related macular degeneration and diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol (2007) 1.14
Are low inflammatory reactions involved in exudative age-related macular degeneration? Morphological and immunhistochemical analysis of AMD associated with basal deposits. Graefes Arch Clin Exp Ophthalmol (2008) 1.13
Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages. PLoS One (2010) 1.10
Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response. Proc Natl Acad Sci U S A (2005) 1.09
CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents. PLoS Med (2008) 1.09
Mitochondrial dysfunction in retinal diseases. Curr Eye Res (2011) 1.08
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. J Biol Chem (2009) 1.07
How does the macula protect itself from oxidative stress? Mol Aspects Med (2012) 1.06
Senile macular changes in the black African. Br J Ophthalmol (1978) 1.06
Aging and degeneration of the human macula. 1. Outer nuclear layer and photoreceptors. Br J Ophthalmol (1981) 1.06
Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci (2015) 1.06
A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap. Invest Ophthalmol Vis Sci (2010) 1.06
Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens. Br J Ophthalmol (1994) 1.06
The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci (2015) 1.05
A rat model for choroidal neovascularization using subretinal lipid hydroperoxide injection. Am J Pathol (2010) 1.05
CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits. Aging (Albany NY) (2010) 1.04
Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model. PLoS One (2013) 1.03
Development of atrophy of the retinal pigment epithelium around disciform scars. Br J Ophthalmol (2006) 1.01
Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye. Proc Natl Acad Sci U S A (2015) 1.01
Dehiscences of the pigment epithelium. Trans Am Ophthalmol Soc (1985) 1.00
A twin study on age-related macular degeneration. Trans Am Ophthalmol Soc (1994) 1.00
Type IV collagen and laminin in Bruch's membrane and basal linear deposit in the human macula. Br J Ophthalmol (1992) 1.00
The APO(*)E3-Leiden mouse as an animal model for basal laminar deposit. Br J Ophthalmol (2000) 0.99
Convolution in human rods: an ageing process. Br J Ophthalmol (1979) 0.98
Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina. Mol Vis (2010) 0.98
Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane. Invest Ophthalmol Vis Sci (2008) 0.97
Impaired expression of thrombospondin-1 in eyes with age related macular degeneration. Br J Ophthalmol (2006) 0.97
CTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways. Invest Ophthalmol Vis Sci (2008) 0.96
Age-related Bruch's membrane change: a clinical study of the relative role of heredity and environment. Br J Ophthalmol (1993) 0.96
Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit. Mol Vis (2007) 0.96
Retinal pigment epithelial acid lipase activity and lipoprotein receptors: effects of dietary omega-3 fatty acids. Trans Am Ophthalmol Soc (2002) 0.95
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration. Elife (2016) 0.93
Abundance of infiltrating CD163+ cells in the retina of postmortem eyes with dry and neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2015) 0.93
Preparation of Bruch's membrane and analysis of the age-related changes in the structural collagens. Br J Ophthalmol (1995) 0.93
Visual function and course of basal laminar drusen combined with vitelliform macular detachment. Br J Ophthalmol (1994) 0.92
Intravitreal ranibizumab for symptomatic drusenoid pigment epithelial detachment without choroidal neovascularization in age-related macular degeneration. Clin Ophthalmol (2011) 0.91
RPE necroptosis in response to oxidative stress and in AMD. Ageing Res Rev (2015) 0.91
Monocular optokinetic nystagmus in humans with age-related maculopathy. Br J Ophthalmol (1997) 0.90
Natural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets. Invest Ophthalmol Vis Sci (2012) 0.90
Automated three-dimensional choroidal vessel segmentation of 3D 1060 nm OCT retinal data. Biomed Opt Express (2012) 0.89
Aceruloplasminemia: retinal histopathologic manifestations and iron-mediated melanosome degradation. Arch Ophthalmol (2011) 0.89
Histopathology of mitochondrial cytopathy and the Laurence-Moon-Biedl syndrome. Br J Ophthalmol (1986) 0.89
Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration. EMBO Mol Med (2015) 0.89
Analysis of retinal pigment epithelium integrin expression and adhesion to aged submacular human Bruch's membrane. Trans Am Ophthalmol Soc (2003) 0.88
Mice that produce ApoB100 lipoproteins in the RPE do not develop drusen yet are still a valuable experimental system. Invest Ophthalmol Vis Sci (2014) 0.87
Clinical characteristics and current treatment of age-related macular degeneration. Cold Spring Harb Perspect Med (2014) 0.87
Age-Related Macular Degeneration: Advances in Management and Diagnosis. J Clin Med (2015) 0.87
Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2007) 0.86
Conditional gene targeting: dissecting the cellular mechanisms of retinal degenerations. J Ophthalmol (2010) 0.86
The Onion Sign in Neovascular Age-Related Macular Degeneration Represents Cholesterol Crystals. Ophthalmology (2015) 0.85
Fundus dystrophy with unusual features; a histological study. Br J Ophthalmol (1951) 2.29
Vascular basement membrane changes in diabetic retinopathy. Montgomery lecture, 1973. Br J Ophthalmol (1974) 2.23
Bruch's membrane and disease of the macula. Role of elastic tissue and collagen. Trans Ophthalmol Soc U K (1967) 2.05
Geographic atrophy of the retinal pigment epithelium. A manifestation of senile macular degeneration. Arch Ophthalmol (1975) 2.03
Further observations on the fine structure of the cornea. Invest Ophthalmol (1962) 1.91
Renal hyalin. A study of amyloidosis and diabetic fibrinous vasculosis with new staining methods. J Clin Pathol (1972) 1.83
Senile changes in visual acuity. Trans Ophthalmol Soc U K (1975) 1.74
Senile disciform degeneration of the macula. Retinal arterialization of the fibrous plaque demonstrated clinically and histopathologically. Arch Ophthalmol (1971) 1.74
Macular lesions of vascular origin. Am J Ophthalmol (1951) 1.62
Fuchs' endothelial dystrophy of the cornea. 29th Sanford Gifford Memorial lecture. Am J Ophthalmol (1974) 1.43
Electron microscopic studies of the human eye. I. Preliminary investigations of the trabeculas. Am J Ophthalmol (1958) 1.37
Broad-banded striated bodies in the sensory epithelium of the human macula and in neurinoma. Nature (1965) 1.34
Fine structure of mesodermal tissues of the human eye. Trans Ophthalmol Soc U K (1974) 1.14
Survey of needs in ophthalmic research and development. Am J Ophthalmol (1973) 1.09
Evolution of geographic atrophy of the retinal pigment epithelium. Eye (Lond) (1988) 4.47
New vessel formation beneath the retinal pigment epithelium in senile eyes. Br J Ophthalmol (1973) 2.43
Council Lecture. Drusen and their relationship to senile macular degeneration. Aust J Ophthalmol (1980) 2.08
Swelling and loss of photoreceptors in chronic human and experimental glaucomas. Arch Ophthalmol (2000) 1.89
Reticular pseudodrusen. A risk factor in age-related maculopathy. Retina (1995) 1.88
Macrophages related to Bruch's membrane in age-related macular degeneration. Eye (Lond) (1990) 1.87
Morphology of early choroidal neovascularisation in age-related macular degeneration: correlation with activity. Eye (Lond) (1997) 1.80
Senile macular degeneration: the involvement of immunocompetent cells. Graefes Arch Clin Exp Ophthalmol (1985) 1.66
Evolution of soft drusen in age-related macular degeneration. Eye (Lond) (1994) 1.54
Indocyanine green angiography of drusen. Am J Ophthalmol (1997) 1.47
Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration. Br J Ophthalmol (2009) 1.37
Extracts from "clinical evidence": age related macular degeneration. BMJ (2000) 1.22
Softening of drusen and subretinal neovascularization. Trans Ophthalmol Soc U K (1980) 1.20
Treatment of choroidal neovascularisation in age-related macular degeneration with interferon alfa-2a and alfa-2b. Br J Ophthalmol (1993) 1.15
Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium. Invest Ophthalmol Vis Sci (1986) 1.05
Adult vitelliform macular degeneration: a clinicopathological study. Eye (Lond) (2003) 0.92
Distribution of cathepsin D in human eyes with or without age-related maculopathy. Exp Eye Res (1999) 0.91
Drusen patterns predisposing to geographic atrophy of the retinal pigment epithelium. Aust J Ophthalmol (1982) 0.87
Adult vitelliform macular degeneration: a clinical spectrum. Aust N Z J Ophthalmol (1990) 0.80
The fellow eye in senile disciform degeneration. Trans Aust Coll Ophthalmol (1970) 0.78
Senile choroidal sclerosis. Br J Ophthalmol (1973) 0.77
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