Identification of two regions in apolipoprotein B100 that are exposed on the cytosolic side of the endoplasmic reticulum membrane.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 2132751)

Published in J Cell Biol on May 04, 1998

Authors

X Du1, J D Stoops, J R Mertz, C M Stanley, J L Dixon

Author Affiliations

1: Department of Food Science and Human Nutrition, University of Missouri, Columbia, Missouri 65211, USA.

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71

Intracellular aspects of the process of protein synthesis. Science (1975) 25.21

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature (1996) 7.90

Cholesterol and the Golgi apparatus. Science (1993) 5.45

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J (1997) 2.92

Morphological analysis of protein transport from the ER to Golgi membranes in digitonin-permeabilized cells: role of the P58 containing compartment. J Cell Biol (1992) 2.44

Complete protein sequence and identification of structural domains of human apolipoprotein B. Nature (1986) 2.12

Intrahepatic assembly of very low density lipoproteins. Rate of transport out of the endoplasmic reticulum determines rate of secretion. J Biol Chem (1987) 1.95

Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys (1989) 1.90

The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70. J Biol Chem (1997) 1.87

Subcellular localization of B apoprotein of plasma lipoproteins in rat liver. J Cell Biol (1976) 1.81

Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B. J Biol Chem (1991) 1.73

Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: information obtained from cultured liver cells. J Lipid Res (1993) 1.68

Basolateral protein transport in streptolysin O-permeabilized MDCK cells. J Cell Biol (1994) 1.64

Studies on the assembly of apolipoprotein B-100- and B-48-containing very low density lipoproteins in McA-RH7777 cells. J Biol Chem (1994) 1.46

Reassessment of the subcellular localization of p63. J Cell Sci (1995) 1.29

Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms. J Biol Chem (1996) 1.24

Apolipoprotein B is both integrated into and translocated across the endoplasmic reticulum membrane. Evidence for two functionally distinct pools. J Biol Chem (1990) 1.23

Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B. Biochemistry (1996) 1.19

Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol. Cell (1996) 1.17

Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein. J Biol Chem (1997) 1.15

Intracellular degradation of newly synthesized apolipoprotein B. J Lipid Res (1997) 1.15

Introduction of macromolecules into bovine adrenal medullary chromaffin cells and rat pheochromocytoma cells (PC12) by permeabilization with streptolysin O: inhibitory effect of tetanus toxin on catecholamine secretion. J Neurochem (1989) 1.10

Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment. J Biol Chem (1990) 1.10

apoB-100 has a pentapartite structure composed of three amphipathic alpha-helical domains alternating with two amphipathic beta-strand domains. Detection by the computer program LOCATE. Arterioscler Thromb (1994) 1.08

Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes. Biochem J (1996) 1.07

Oleate-mediated stimulation of apolipoprotein B secretion from rat hepatoma cells. A function of the ability of apolipoprotein B to direct lipoprotein assembly and escape presecretory degradation. J Biol Chem (1992) 1.02

Assembly of rat hepatic very low density lipoproteins in the endoplasmic reticulum. J Biol Chem (1993) 1.01

New variation on the translocation of proteins during early biogenesis of apolipoprotein B. Nature (1990) 0.99

Apolipoprotein B sequence requirements for hepatic very low density lipoprotein assembly. Evidence that hydrophobic sequences within apolipoprotein B48 mediate lipid recruitment. J Biol Chem (1996) 0.98

Evidence that during very low density lipoprotein assembly in rat hepatocytes most of the triacylglycerol and phospholipid are packaged with apolipoprotein B in the Golgi complex. FEBS Lett (1988) 0.98

Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells. J Biol Chem (1993) 0.98

Regulated intracellular degradation of apolipoprotein B in semipermeable HepG2 cells. J Biol Chem (1994) 0.93

Intracellular assembly of human fibrinogen. J Biol Chem (1983) 0.93

Studies of the sites of intracellular degradation of apolipoprotein B in Hep G2 cells. J Biol Chem (1992) 0.92

Synchronized synthesis and intracellular transport of serum albumin and apolipoprotein B in cultured rat hepatocytes as studied by double immunofluorescence. J Histochem Cytochem (1986) 0.90

Possible role of the Golgi apparatus in the assembly of very low density lipoprotein. Proc Natl Acad Sci U S A (1990) 0.89

Impaired biosynthesis of phosphatidylcholine causes a decrease in the number of very low density lipoprotein particles in the Golgi but not in the endoplasmic reticulum of rat liver. J Biol Chem (1993) 0.87

Regional specificities of monoclonal anti-human apolipoprotein B antibodies. J Lipid Res (1988) 0.87

Hepatic polysomes that contain apoprotein B mRNA have unusual physical properties. J Biol Chem (1993) 0.86

Movement of apolipoprotein B into the lumen of microsomes from hepatocytes is disrupted in membranes enriched in phosphatidylmonomethylethanolamine. J Biol Chem (1993) 0.86

Influence of triacylglycerol biosynthesis rate on the assembly of apoB-100-containing lipoproteins in Hep G2 cells. Arterioscler Thromb (1993) 0.85

Double immunofluorescent staining of alpha 2,6 sialyltransferase and beta 1,4 galactosyltransferase in monensin-treated cells: evidence for different Golgi compartments? J Cell Biochem (1993) 0.83

Apolipoprotein B is intracellularly associated with an ER-60 protease homologue in HepG2 cells. J Biol Chem (1997) 0.83

Degradation of apolipoprotein B in cultured rat hepatocytes occurs in a post-endoplasmic reticulum compartment. J Biol Chem (1995) 0.82

Intracellular degradation in the regulation of secretion of apolipoprotein B-100 by rabbit hepatocytes. Biochem J (1996) 0.81

Apoprotein B100, an inefficiently translocated secretory protein, is bound to the cytosolic chaperone, heat shock protein 70. J Biol Chem (1995) 0.81

Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane. J Lipid Res (1996) 0.81

Apolipoprotein B48-membrane interactions. Absence of transmembrane localization in nonhepatic cells. J Biol Chem (1994) 0.80

Topography of apolipoprotein B in subcellular fractions of rabbit liver probed with a panel of monoclonal antibodies. J Lipid Res (1993) 0.80

Permeabilization of MDCK cells with cholesterol binding agents: dependence on substratum and confluency. Am J Physiol (1994) 0.79

Studies on intracellular translocation of apolipoprotein B in a permeabilized HepG2 system. J Biol Chem (1997) 0.79

Biosynthesis of lipoprotein: location of nascent apoAI and apoB in the rough endoplasmic reticulum of chicken hepatocytes. J Cell Biol (1992) 0.79

In HepG2 cells, translocation, not degradation, determines the fate of the de novo synthesized apolipoprotein B. J Biol Chem (1995) 0.79

Proteolysis-coupled secretion of the N terminus of apolipoprotein B. Characterization of a transient, translocation arrested intermediate. J Biol Chem (1994) 0.78

Differentiation of intrahepatic membrane-bound and secretory apolipoprotein B by monoclonal antibodies: membrane-bound apolipoprotein B is more glycosylated. Biochemistry (1994) 0.77

Studies on the translocation of the amino terminus of apolipoprotein B into the endoplasmic reticulum. J Biol Chem (1995) 0.77

Systematic expression of the complete coding sequence of apoB-100 does not reveal transmembrane determinants. J Lipid Res (1996) 0.76

Asymmetric distribution of pause transfer sequences in apolipoprotein B-100. J Lipid Res (1997) 0.76

Articles by these authors

Improving the quality of emergency department documentation using the voice-activated word processor: interim results. Proc Annu Symp Comput Appl Med Care (1992) 3.01

Plant cells contain two functionally distinct vacuolar compartments. Cell (1996) 2.94

An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity. J Immunol Methods (1988) 2.27

Adherence of Vibrio cholerae to cultured differentiated human intestinal cells: an in vitro colonization model. Infect Immun (1997) 1.55

Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells. J Biol Chem (1985) 1.30

Dyslipidemia and vascular dysfunction in diabetic pigs fed an atherogenic diet. Arterioscler Thromb Vasc Biol (1999) 1.29

Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol. J Biol Chem (2001) 1.23

Biochemical characteristics of isolated rat liver stellate cells. Hepatology (1988) 1.22

Jehovah's Witnesses. The surgical/ethical challenge. JAMA (1981) 1.21

Subunit dimers in sheep spleen apoferritin. The effect on iron storage. J Biol Chem (1983) 1.18

Mutations in BTD causing biotinidase deficiency. Hum Mutat (2001) 1.16

Substrate specificities and 13-cis-retinoic acid inhibition of human, mouse and bovine cis-retinol dehydrogenases. Biochim Biophys Acta (2000) 1.14

A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient. Gut (2003) 1.08

Influence of the T-helper epitope on the titre and affinity of antibodies to B-cell epitopes after co-immunization. Mol Immunol (1993) 1.07

The affinity of IgG antibodies to gag p24 and p17 in HIV-1-infected patients correlates with disease progression. Clin Exp Immunol (1995) 1.03

Influence of antibody affinity on the performance of different antibody assays. J Immunol Methods (1984) 1.03

Modulation of bovine papillomavirus DNA replication by phosphorylation of the viral E1 protein. Virology (1997) 1.02

High-affinity antibody induced by immunization with a synthetic peptide is associated with protection of cattle against foot-and-mouth disease. Immunology (1991) 0.99

Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells. J Biol Chem (1993) 0.98

Immune responses in mice following immunization with chimeric synthetic peptides representing B and T cell epitopes of measles virus proteins. J Gen Virol (1991) 0.98

Influence of retinoid nutritional status on cellular retinol- and cellular retinoic acid-binding protein concentrations in various rat tissues. J Biol Chem (1985) 0.98

Biochemical properties, tissue expression, and gene structure of a short chain dehydrogenase/ reductase able to catalyze cis-retinol oxidation. J Lipid Res (1999) 0.95

Studies on the in vivo transfer of retinoids from parenchymal to stellate cells in rat liver. Eur J Biochem (1987) 0.95

Localization of retinoid binding proteins, retinoid receptors, and retinaldehyde dehydrogenase in the chick eye. J Neurocytol (1999) 0.95

The absence of loss of antibodies of high affinity to human immunodeficiency virus (HIV) is associated with disease progression in HIV-1-infected patients. J Infect Dis (1995) 0.93

A mimotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response. J Virol (1995) 0.93

Studies of the sites of intracellular degradation of apolipoprotein B in Hep G2 cells. J Biol Chem (1992) 0.92

Atorvastatin treatment prevents alterations in coronary smooth muscle nuclear Ca2+ signaling in diabetic dyslipidemia. J Vasc Res (2002) 0.92

Hereditary factor VII deficiency: heterogeneity defined by combined functional and immunochemical analysis. Blood (1985) 0.92

The decarboxylation of alpha-keto-gamma-methiolbutyrate in rat liver mitochondria. Biochem Biophys Res Commun (1980) 0.92

Cellular retinoic acid- and cellular retinol-binding proteins: complementary deoxyribonucleic acid cloning, chromosomal assignment, and tissue specific expression. Mol Endocrinol (1987) 0.87

Colonial opacity variations among the choleragenic vibrios. Microbiology (1997) 0.87

Detection of Bifidobacterium species and Gardnerella vaginalis in the vagina using PCR and denaturing gradient gel electrophoresis (DGGE). Int J Gynaecol Obstet (2003) 0.86

Immunological analysis of the protective responses to the chimeric synthetic peptide representing T- and B-cell epitopes from the fusion protein of measles virus. Virus Res (1996) 0.85

Increased endothelin-induced Ca2+ signaling, tyrosine phosphorylation, and coronary artery disease in diabetic dyslipidemic Swine are prevented by atorvastatin. J Pharmacol Exp Ther (2003) 0.84

Effect of atorvastatin on intracellular calcium uptake in coronary smooth muscle cells from diabetic pigs fed an atherogenic diet. Atherosclerosis (2001) 0.81

The effect of 16,16-dimethyl prostaglandin E2 on proliferation of an intestinal goblet cell line and its synthesis and secretion of mucin glycoproteins. Prostaglandins Leukot Essent Fatty Acids (1993) 0.81

Ferroportin disease due to the A77D mutation in Australia. Gut (2005) 0.80

Effects on plasma amino acid concentrations and hepatic branched-chain alpha-keto acid dehydrogenase activity of feeding rats diets containing 9 or 50% casein. J Nutr (1984) 0.79

Effects of dietary retinoic acid on cellular retinol- and retinoic acid-binding protein levels in various rat tissues. J Lipid Res (1986) 0.79

Studies on the metabolism of retinol-binding protein by primary hepatocytes from retinol-deficient rats. J Cell Physiol (1987) 0.79

Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells. J Lipid Res (2001) 0.79

Intrathymic distribution of the two avian thymic parvalbumins. Exp Cell Res (1996) 0.79

Purification, partial characterization, and localization of Sak57, an acidic intermediate filament keratin present in rat spermatocytes, spermatids, and sperm. Mol Reprod Dev (1996) 0.78

Retinol-binding protein synthesis and secretion by the rat visceral yolk sac. Effect of retinol status. J Biol Chem (1988) 0.77

Effects of perfusate leucine concentration on the metabolism of valine by the isolated rat hindquarter. Metabolism (1984) 0.77

Intracellular apoprotein B degradation is suppressed by decreased albumin concentration in Hep G2 cells. Kidney Int (1995) 0.77

Alterations in the oxidative metabolic profile in vascular smooth muscle from hyperlipidemic and diabetic swine. Mol Cell Biochem (2001) 0.77

Ubiquitin-proteasome-dependent degradation of apolipoprotein B100 in vitro. Biochim Biophys Acta (1999) 0.76

Scar revision and dermabrasion. J Med Assoc Ga (1991) 0.75

A drill for use in an inaccessible place. Plast Reconstr Surg (1976) 0.75

A simple method for mounting 70 mm. spot film. Radiol Technol (1970) 0.75

Rat Sertoli and spermatogenic cells express a similar gene, and its product is antigenically related to an outer dense fiber-associated protein. Mol Reprod Dev (1992) 0.75

Treatment of benign prostatic hypertrophy. Hosp Pract (1980) 0.75

Broadening career opportunities in dietetics: employment in independent research. J Am Diet Assoc (1999) 0.75

Bimonthly update: lipidology. Lipid metabolism. Curr Opin Lipidol (1997) 0.75

Oral midazolam premedication for paediatric day case patients. Paediatr Anaesth (1996) 0.75

Galactosyl receptor in human testis and sperm is antigenically related to the minor C-type (Ca(2+)-dependent) lectin variant of human and rat liver. Mol Reprod Dev (1995) 0.75

Drug sensitivity. Med Leg Bull (1968) 0.75

Cytosolic components are required for proteasomal degradation of newly synthesized apolipoprotein B in permeabilized HepG2 cells. J Biol Chem (1999) 0.75

Use of cyclodextrin to deliver lipids and to modulate apolipoprotein B-100 production in HepG2 cells. Lipids (1997) 0.75

Jehovah's Witnesses and blood transfusion. Conn Med (1975) 0.75

Blood: whose choice and whose conscience? N Y State J Med (1988) 0.75

Effects of nutritional and hormonal factors on the metabolism of retinol-binding protein by primary cultures of rat hepatocytes. J Cell Physiol (1987) 0.75

Influence of retinoids on bladder cancer growth as detected by primary tissue culture. Br J Urol (1990) 0.75

Lipid metabolism. Curr Opin Lipidol (1994) 0.75