Published in Nature on April 23, 1998
A coarse-grained normal mode approach for macromolecules: an efficient implementation and application to Ca(2+)-ATPase. Biophys J (2002) 2.26
Homology modeling of the cation binding sites of Na+K+-ATPase. Proc Natl Acad Sci U S A (2002) 1.85
Structure of a copper pump suggests a regulatory role for its metal-binding domain. Structure (2008) 1.74
The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria. Proc Natl Acad Sci U S A (2002) 1.66
Evolutionary relationship between K(+) channels and symporters. Biophys J (1999) 1.63
Reconstruction of helical filaments and tubes. Methods Enzymol (2010) 1.51
Sarcolipin regulates sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban. Proc Natl Acad Sci U S A (2003) 1.48
Normal mode-based fitting of atomic structure into electron density maps: application to sarcoplasmic reticulum Ca-ATPase. Biophys J (2004) 1.46
GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model. J Gen Physiol (1999) 1.46
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle. Biochem J (1999) 1.44
Crystallization of a mammalian membrane protein overexpressed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2005) 1.36
Structural similarities of Na,K-ATPase and SERCA, the Ca(2+)-ATPase of the sarcoplasmic reticulum. Biochem J (2001) 1.33
Transconformations of the SERCA1 Ca-ATPase: a normal mode study. Biophys J (2003) 1.22
Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands. J Gen Physiol (2004) 1.22
Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle. EMBO J (2009) 1.20
The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival. Mol Biol Cell (2008) 1.17
Kinetics of the Ca(2+), H(+), and Mg(2+) interaction with the ion-binding sites of the SR Ca-ATPase. Biophys J (2002) 1.12
Locating phospholamban in co-crystals with Ca(2+)-ATPase by cryoelectron microscopy. Biophys J (2001) 1.11
Interactions between Ca2+-ATPase and the pentameric form of phospholamban in two-dimensional co-crystals. Biophys J (2006) 1.06
Subunit composition, structure, and distribution of bacterial V-type ATPases. J Bioenerg Biomembr (2003) 1.05
Identification of the Mg2+-binding site in the P-type ATPase and phosphatase members of the HAD (haloacid dehalogenase) superfamily by structural similarity to the response regulator protein CheY. Biochem J (1999) 1.04
Fourier-Bessel reconstruction of helical assemblies. Methods Enzymol (2010) 0.99
Concerted conformational effects of Ca2+ and ATP are required for activation of sequential reactions in the Ca2+ ATPase (SERCA) catalytic cycle. Biochemistry (2006) 0.96
Structure of Na+,K+-ATPase at 11-A resolution: comparison with Ca2+-ATPase in E1 and E2 states. Biophys J (2001) 0.93
Modeling a dehalogenase fold into the 8-A density map for Ca(2+)-ATPase defines a new domain structure. Biophys J (2000) 0.89
Damped-dynamics flexible fitting. Biophys J (2008) 0.89
The mechanics of calcium transport. J Membr Biol (2004) 0.86
Application of the iterative helical real-space reconstruction method to large membranous tubular crystals of P-type ATPases. J Struct Biol (2006) 0.86
Present and future of membrane protein structure determination by electron crystallography. Adv Protein Chem Struct Biol (2010) 0.85
Molecular mechanism of the P-type ATPases. J Bioenerg Biomembr (2002) 0.84
A new twist on protein crystallization. Proc Natl Acad Sci U S A (1998) 0.82
Role of transmembrane segment M8 in the biogenesis and function of yeast plasma-membrane H(+)-ATPase. Biochim Biophys Acta (2007) 0.81
Alzheimer's disease: A hypothesis on pathogenesis. J Am Aging Assoc (2000) 0.81
Structural organization and energy transduction mechanism of Na+,K+-ATPase studied with transition metal-catalyzed oxidative cleavage. J Bioenerg Biomembr (2001) 0.81
The architecture of CopA from Archeaoglobus fulgidus studied by cryo-electron microscopy and computational docking. Structure (2011) 0.81
Two-dimensional crystallization of Ca-ATPase by detergent removal. Biophys J (1998) 0.81
Phospholamban domain IB forms an interaction site with the loop between transmembrane helices M6 and M7 of sarco(endo)plasmic reticulum Ca2+ ATPases. Proc Natl Acad Sci U S A (2001) 0.81
Characterization of calcium, nucleotide, phosphate, and vanadate bound states by derivatization of sarcoplasmic reticulum ATPase with ThioGlo1. Biophys J (1999) 0.80
Molecular modeling of the rabbit colonic (HKalpha2a) H+, K+ ATPase. J Mol Model (2003) 0.80
Deducing the symmetry of helical assemblies: Applications to membrane proteins. J Struct Biol (2016) 0.76
Mechanistic study of modulation of SR Ca2+-ATPpase activity by gangliosides GM1 and GM3 through some biophysical measurements. Glycoconj J (1999) 0.76
Tubular crystals and helical arrays: structural determination of HIV-1 capsid assemblies using iterative helical real-space reconstruction. Methods Mol Biol (2013) 0.76
Profile of Chikashi Toyoshima. Proc Natl Acad Sci U S A (2006) 0.75
Decoding P4-ATPase substrate interactions. Crit Rev Biochem Mol Biol (2016) 0.75
A feast of membrane protein structures in Madrid. Workshop: Pumps, channels and transporters: structure and function. EMBO Rep (2001) 0.75
Electron Microscopy: From 2D to 3D Images with Special Reference to Muscle. Eur J Transl Myol (2015) 0.75
Avidin. Adv Protein Chem (1975) 10.27
Avidin and streptavidin. Methods Enzymol (1990) 5.47
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs (1996) 5.45
Amino-acid sequence of a Ca2+ + Mg2+-dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence. Nature (1985) 4.68
Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. J Biol Chem (1990) 4.35
Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. J Biol Chem (1990) 3.87
Electron microscopy of an antibody-hapten complex. J Mol Biol (1967) 3.63
Myosin subfragment-1 is sufficient to move actin filaments in vitro. Nature (1987) 3.44
Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences. Cell (1986) 3.18
Reduced myocardial flow reserve in non-insulin-dependent diabetes mellitus. J Am Coll Cardiol (1997) 2.11
The mechanism of Ca2+ transport by sarco(endo)plasmic reticulum Ca2+-ATPases. J Biol Chem (1997) 2.04
The role of calcium ions in initiating transformation of lymphocytes. Nature (1974) 2.01
The fixation of complement and the activated first component (C1) of complement by complexes formed between antibody and divalent hapten. J Exp Med (1970) 1.90
Three-dimensional cryo-electron microscopy of the calcium ion pump in the sarcoplasmic reticulum membrane. Nature (1993) 1.82
Surface-enhanced Raman gene probes. Anal Chem (1994) 1.73
Electron microscopy and structural model of human fibronectin receptor. EMBO J (1988) 1.69
Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix. EMBO J (1984) 1.63
Identification of a labelled peptide after stoicheiometric reaction of fluorescein isothiocyanate with the Ca2+ -dependent adenosine triphosphatase of sarcoplasmic reticulum. FEBS Lett (1982) 1.59
The effect of delipidation on the adenosine triphosphatase of sarcoplasmic reticulum. Electron microscopy and physical properties. Eur J Biochem (1974) 1.55
Electron microscopy of the immunoglobulins. Adv Immunol (1969) 1.52
Purification and crystallization of avidin. Biochem J (1970) 1.52
The structure of the R-type straight flagellar filament of Salmonella at 9 A resolution by electron cryomicroscopy. J Mol Biol (1995) 1.47
A method for alpha-helical integral membrane protein fold prediction. Proteins (1994) 1.42
The properties of subunits of avidin coupled to sepharose. Biochem J (1973) 1.42
A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA. EMBO J (1991) 1.42
Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: population genetics, human serologic response, and gene transcription. Proc Natl Acad Sci U S A (2001) 1.41
Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes. J Cell Biol (1988) 1.41
Long-term effect of simvastatin on the improvement of impaired myocardial flow reserve in patients with familial hypercholesterolemia without gender variance. J Nucl Cardiol (2001) 1.40
Structure of the rabbit fast-twitch skeletal muscle Ca2+-ATPase gene. J Biol Chem (1988) 1.38
A preliminary crystallographic investigation of avidin. Biochem J (1970) 1.36
Secondary structure and orientation of phospholamban reconstituted in supported bilayers from polarized attenuated total reflection FTIR spectroscopy. Biochemistry (1995) 1.35
Molecular cloning and differential expression of the maize ferredoxin gene family. Plant Physiol (1991) 1.33
The variable twist of actin and its modulation by actin-binding proteins. J Cell Biol (1987) 1.33
Surface-enhanced Raman gene probe for HIV detection. Anal Chem (1998) 1.32
Three-dimensional crystals of CaATPase from sarcoplasmic reticulum. Symmetry and molecular packing. Biophys J (1990) 1.32
Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. Circ Res (2001) 1.30
Studies on the location and orientation of proteins in the sarcoplasmic reticulum. Eur J Biochem (1973) 1.27
A structural feature in the central channel of the bacterial flagellar FliF ring complex is implicated in type III protein export. J Struct Biol (1998) 1.25
The use of bifunctional biotinyl compounds to determine the arrangement of subunits in avidin. Biochem J (1971) 1.23
A 31-residue tryptic peptide from the active site of the [Ca++]-transporting adenosine triphosphatase of rabbit sarcoplasmic reticulum. FEBS Lett (1976) 1.22
Calreticulin is a candidate for a calsequestrin-like function in Ca2(+)-storage compartments (calciosomes) of liver and brain. Biochem J (1990) 1.21
Detailed characterization of the cooperative mechanism of Ca(2+) binding and catalytic activation in the Ca(2+) transport (SERCA) ATPase. Biochemistry (2000) 1.20
Functional reconstitution of recombinant phospholamban with rabbit skeletal Ca(2+)-ATPase. J Biol Chem (1995) 1.19
Optical rotatory dispersion, circular dichroism and far-ultraviolet spectra of avidin and streptavidin. Biochem J (1966) 1.19
The effect of N-bromosuccinimide on the sub-unit structure of acidin and its complexes with biotin. Biochem J (1968) 1.11
Locating phospholamban in co-crystals with Ca(2+)-ATPase by cryoelectron microscopy. Biophys J (2001) 1.11
Organization of cytoplasmic domains of sarcoplasmic reticulum Ca(2+)-ATPase in E(1)P and E(1)ATP states: a limited proteolysis study. FEBS Lett (2001) 1.08
Avidin. 5. Quenching of fluorescence by dinitrophenyl groups. Biochem J (1964) 1.08
The predicted secondary structures of the nucleotide-binding sites of six cation-transporting ATPases lead to a probable tertiary fold. Eur J Biochem (1989) 1.07
Bidirectional movement of actin filaments along tracks of myosin heads. Nature (1989) 1.07
Temperature-induced change of thick filament and location of the functional sites of myosin. Adv Exp Med Biol (1988) 1.07
The reactivity of the thiol groups of the adenosine triphosphatase of sarcoplasmic reticulum and their location on tryptic fragments of the molecule. Biochem J (1977) 1.06
Location of the ATPase site of myosin determined by three-dimensional electron microscopy. Nature (1987) 1.06
Calcineurin is activated in rat hearts with physiological left ventricular hypertrophy induced by voluntary exercise training. Circulation (2000) 1.06
Molecular and biochemical characterization of three anthocyanin synthetic enzymes from Gentiana triflora. Plant Cell Physiol (1996) 1.03
Molecular cloning and expression of cDNA encoding the 53,000-dalton glycoprotein of rabbit skeletal muscle sarcoplasmic reticulum. J Biol Chem (1989) 1.03
Evidence for a genetic relationship between avidins and lysozymes. Nature (1968) 1.01
How to make tubular crystals by reconstitution of detergent-solubilized Ca2(+)-ATPase. Biophys J (1997) 1.01
Molecular cloning and expression of cDNA encoding a lumenal calcium binding glycoprotein from sarcoplasmic reticulum. Proc Natl Acad Sci U S A (1989) 1.01
Transcarboxylase. XI. Electron microscopy and subunit structure. J Biol Chem (1972) 1.01
Purified, reconstituted cardiac Ca2+-ATPase is regulated by phospholamban but not by direct phosphorylation with Ca2+/calmodulin-dependent protein kinase. J Biol Chem (1996) 1.00
Primary structures of cysteine-containing peptides from the calcium ion-transporting adenosine triphosphatase of rabbit sarcoplasmic reticulum. Biochem J (1978) 1.00
Structure, transmembrane topology and helix packing of P-type ion pumps. FEBS Lett (1994) 1.00
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. Angiogenesis (2001) 0.99
Structure of CaATPase: electron microscopy of frozen-hydrated crystals at 6 A resolution in projection. J Mol Biol (1990) 0.99
Structure determination of tubular crystals of membrane proteins. III. Solvent flattening. Ultramicroscopy (2000) 0.99
ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca(2+)-ATPase has a compact conformation resistant to proteinase K, V8 protease and trypsin. FEBS Lett (2001) 0.99
Structural biology. Pumping ions. Nature (2000) 0.98
Separation and characterisation of tryptic fragments from the adenosine triphosphatase of sarcoplasmic reticulum. Eur J Biochem (1975) 0.97
Nonlinear increases in diffusing capacity during exercise by seated and supine subjects. J Appl Physiol Respir Environ Exerc Physiol (1981) 0.95
Structure determination of tubular crystals of membrane proteins. II. Averaging of tubular crystals of different helical classes. Ultramicroscopy (2000) 0.95
Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene. Nucleic Acids Res (1987) 0.94
The reactivity toward N-bromosuccinimide of tryptophan in enzymes, zymogens, and inhibited enzymes. Biochemistry (1966) 0.94
Electron microscopy of complexes between IgA (MOPC 315) and a bifunctional hapten. J Mol Biol (1971) 0.93
The role of the M6-M7 loop (L67) in stabilization of the phosphorylation and Ca(2+) binding domains of the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA). J Biol Chem (2001) 0.93
The ATP-binding site of Ca(2+)-ATPase revealed by electron image analysis. Biophys J (1997) 0.93
Structural and mechanistic implications of the amino acid sequence of calcium-transporting ATPases. Ciba Found Symp (1986) 0.93
The dissociation of avidin-biotin complexes by guanidinium chloride. Biochem J (1972) 0.93
Structure of Na+,K+-ATPase at 11-A resolution: comparison with Ca2+-ATPase in E1 and E2 states. Biophys J (2001) 0.93
Averaging data derived from images of helical structures with different symmetries. J Mol Biol (1999) 0.92
Kinetics of the cooperativity of the Ca2+-transporting adenosine triphosphatase of sarcoplasmic reticulum and the mechanism of the ATP interaction. Arch Biochem Biophys (1977) 0.92
Three-dimensional image analysis of the complex of thin filaments and myosin molecules from skeletal muscle. V. Assignment of actin in the actin-tropomyosin-myosin subfragment-1 complex. J Biochem (1985) 0.91
The accessibility of protein-bound dinitrophenyl groups to univalent fragments of anti-dinitrophenyl antibody. Biochem J (1976) 0.91
Biological membranes. The semiotics of charge. Nature (1991) 0.91
The sarcoplasmic reticulum Ca2+-ATPase (SERCA2) gene promoter activity is decreased in response to severe left ventricular pressure-overload hypertrophy in rat hearts. J Mol Cell Cardiol (1999) 0.91
Structure of the Ca2+ pump of sarcoplasmic reticulum: a view along the lipid bilayer at 9-A resolution. Biophys J (1998) 0.91
Neurobehavioral and immunological effects of prenatal cocaine exposure in rat. Pharmacol Biochem Behav (1990) 0.91
1H-NMR studies on nucleotide binding to the sarcoplasmic reticulum Ca2+ ATPase. Determination of the conformations of bound nucleotides by the measurement of proton-proton transferred nuclear Overhauser enhancements. Eur J Biochem (1982) 0.90
Structural modelling of P-type ion pumps. Acta Physiol Scand Suppl (1992) 0.90
Hyperglycemia rather than insulin resistance is related to reduced coronary flow reserve in NIDDM. Diabetes (1998) 0.89
Modeling a dehalogenase fold into the 8-A density map for Ca(2+)-ATPase defines a new domain structure. Biophys J (2000) 0.89
Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head-Nkin neck chimera with conventional kinesin. EMBO J (2000) 0.88
Three-dimensional structure of bovine cytochrome bc1 complex by electron cryomicroscopy and helical image reconstruction. Nat Struct Biol (1996) 0.87
The prediction of the conformation of membrane proteins from the sequence of amino acids. Biochem J (1976) 0.87
Site-directed disulfide mapping of helices M4 and M6 in the Ca2+ binding domain of SERCA1a, the Ca2+ ATPase of fast twitch skeletal muscle sarcoplasmic reticulum. J Biol Chem (1997) 0.87