DNA condensation for gene therapy as monitored by atomic force microscopy.

PubWeight™: 1.20‹?› | Rank: Top 10%

🔗 View Article (PMC 147577)

Published in Nucleic Acids Res on May 15, 1998

Authors

H G Hansma1, R Golan, W Hsieh, C P Lollo, P Mullen-Ley, D Kwoh

Author Affiliations

1: Department of Physics, University of California, Santa Barbara, CA 93106, USA. hhansma@physics.ucsb.edu

Articles citing this

Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopy. RNA (2000) 1.43

Lipoplex formation under equilibrium conditions reveals a three-step mechanism. Biophys J (2000) 1.29

Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics. J Pharm Sci (2011) 1.24

Imaging of nucleic acids with atomic force microscopy. Methods (2011) 1.13

Effects of the incorporation of a hydrophobic middle block into a PEG-polycation diblock copolymer on the physicochemical and cell interaction properties of the polymer-DNA complexes. Biomacromolecules (2008) 1.02

Formation of DNA nanoparticles in the presence of novel polyamine analogues: a laser light scattering and atomic force microscopic study. Nucleic Acids Res (2004) 1.02

Layer-by-layer deposition of oppositely charged polyelectrolytes on the surface of condensed DNA particles. Nucleic Acids Res (1999) 0.98

Concentration-dependent organization of DNA by the dinoflagellate histone-like protein HCc3. Nucleic Acids Res (2007) 0.92

Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase I. Nucleic Acids Res (2003) 0.92

Surface polyethylene glycol enhances substrate-mediated gene delivery by nonspecifically immobilized complexes. Acta Biomater (2007) 0.90

DNA release dynamics from reducible polyplexes by atomic force microscopy. Langmuir (2008) 0.88

Bacterial protein HU dictates the morphology of DNA condensates produced by crowding agents and polyamines. Nucleic Acids Res (2007) 0.87

DNA release dynamics from bioreducible poly(amido amine) polyplexes. J Phys Chem B (2009) 0.86

Extended, relaxed, and condensed conformations of hyaluronan observed by atomic force microscopy. Biophys J (2004) 0.86

Gene delivery via DNA incorporation within a biomimetic apatite coating. Biomaterials (2009) 0.82

Toroidal condensates of semiflexible polymers in poor solvents: adsorption, stretching, and compression. Biophys J (2001) 0.79

EphA2 targeting peptide tethered bioreducible poly(cystamine bisacrylamide-diamino hexane) for the delivery of therapeutic pCMV-RAE-1γ to pancreatic islets. J Control Release (2011) 0.78

Study on relationship between expression level and molecular conformations of gene drugs targeting to hepatoma cells in vitro. World J Gastroenterol (2003) 0.75

Current status and perspectives in atomic force microscopy-based identification of cellular transformation. Int J Nanomedicine (2016) 0.75

Visualizing the attack of RNase enzymes on dendriplexes and naked RNA using atomic force microscopy. PLoS One (2013) 0.75

Aggregation and adsorption at the air-water interface of bacteriophage phiX174 single-stranded DNA. Biophys J (2007) 0.75

The role of a microscopic colloidally stabilized phase in solubilizing oligoamine-condensed DNA complexes. Biophys J (2003) 0.75

C3-symmetric opioid scaffolds are pH-responsive DNA condensation agents. Nucleic Acids Res (2016) 0.75

Articles cited by this

DNA condensation. Curr Opin Struct Biol (1996) 5.07

Biomolecular imaging with the atomic force microscope. Annu Rev Biophys Biomol Struct (1994) 4.89

DNA condensation with polyamines I. Spectroscopic studies. J Mol Biol (1978) 3.21

DNA condensation with polyamines. II. Electron microscopic studies. J Mol Biol (1978) 3.09

Some factors affecting electron microscopic length of deoxyribonucleic acid. J Mol Biol (1967) 2.38

Escherichia coli RNA polymerase activity observed using atomic force microscopy. Biochemistry (1997) 2.17

Applications for atomic force microscopy of DNA. Biophys J (1995) 1.96

Motion and enzymatic degradation of DNA in the atomic force microscope. Biophys J (1994) 1.93

Characterization of DNA condensates induced by poly(ethylene oxide) and polylysine. Proc Natl Acad Sci U S A (1975) 1.89

Nanoscopic structure of DNA condensed for gene delivery. Nucleic Acids Res (1997) 1.87

Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci U S A (1991) 1.80

Adsorption of biological molecules to a solid support for scanning probe microscopy. J Struct Biol (1997) 1.79

Properties of biomolecules measured from atomic force microscope images: a review. J Struct Biol (1997) 1.65

Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry (1996) 1.60

Gene expression following direct injection of DNA into liver. Hum Gene Ther (1994) 1.59

Recent advances in atomic force microscopy of DNA. Scanning (1994) 1.56

Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits. J Biol Chem (1992) 1.55

Atomic force microscopy of long and short double-stranded, single-stranded and triple-stranded nucleic acids. Nucleic Acids Res (1996) 1.50

Bending and straightening of DNA induced by the same ligand: characterization with the atomic force microscope. Biochemistry (1994) 1.49

AFM analysis of DNA-protamine complexes bound to mica. Nucleic Acids Res (1997) 1.33

Structural changes in native membrane proteins monitored at subnanometer resolution with the atomic force microscope: a review. J Struct Biol (1997) 1.10

Atomic force microscopic analysis of the influence of the molecular weight of poly(L)lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther (1996) 1.09

Gene therapy's growing pains. Science (1995) 1.09

Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor. J Biol Chem (1997) 1.05

An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes. Eur J Biochem (1994) 1.03

Fusigenic viral liposome for gene therapy in cardiovascular diseases. Proc Natl Acad Sci U S A (1996) 0.90

Targeted delivery of antisense oligonucleotides by molecular conjugates. Somat Cell Mol Genet (1992) 0.89

Regulation of the phosphoenolpyruvate carboxykinase/human factor IX gene introduced into the livers of adult rats by receptor-mediated gene transfer. FASEB J (1993) 0.89

Preparation of asialoorosomucoid-polylysine conjugates. Bioconjug Chem (1994) 0.88

Strategies to accomplish gene delivery via the receptor-mediated endocytosis pathway. Cancer Gene Ther (1996) 0.86

Targeted delivery of DNA using YEE(GalNAcAH)3, a synthetic glycopeptide ligand for the asialoglycoprotein receptor. Bioconjug Chem (1995) 0.84

Receptor-mediated DNA delivery approaches to human gene therapy. Biologicals (1995) 0.81

Articles by these authors

Site-specific recombination in phage mu. Cold Spring Harb Symp Quant Biol (1979) 1.58

DNA toroids: stages in condensation. Biochemistry (1999) 1.49

Celecoxib reduces microvessel density in patients treated with nasopharyngeal carcinoma and induces changes in gene expression. Ann Oncol (2006) 1.48

Prevalence of HIV antibodies in transsexual and female prostitutes. Am J Public Health (1992) 1.47

Probing the Saccharomyces cerevisiae centromeric DNA (CEN DNA)-binding factor 3 (CBF3) kinetochore complex by using atomic force microscopy. Proc Natl Acad Sci U S A (1999) 1.33

Population genetics of Schistosoma haematobium: development of novel microsatellite markers and their application to schistosomiasis control in Mali. Parasitology (2011) 1.22

Stabilization of poly-L-lysine/DNA polyplexes for in vivo gene delivery to the liver. Biochim Biophys Acta (1999) 1.14

Phase imaging of moving DNA molecules and DNA molecules replicated in the atomic force microscope. Nucleic Acids Res (1997) 0.95

Probing biopolymers with the atomic force microscope: a review. J Biomater Sci Polym Ed (2000) 0.91

Metabolism in rats in vivo of RS-2-methylbutyrate and n-butyrate labeled with stable isotopes at various positions. Mechanism of biosynthesis and degradation of ethylmalonyl semialdehyde and ethylmalonic acid. J Biol Chem (1979) 0.90

Polymerase activities and RNA structures in the atomic force microscope. J Struct Biol (1999) 0.89

Strength of conjugate binding to plasmid DNA affects degradation rate and expression level in vivo. Biochim Biophys Acta (2000) 0.89

Specific binding of mu repressor to DNA. Nature (1979) 0.87

Varieties of imaging with scanning probe microscopes. Proc Natl Acad Sci U S A (1999) 0.86

Oral phenylalanine and tyrosine tolerance tests in Parkinsonian patients. Br Med J (1969) 0.82

Onset of puberty in the immature female rat induced by 5 -androstane-3 ,17 -diol. Endocrinology (1973) 0.81

Meiosis in the golden hamster: a confocal microscopy and flow cytometric analysis. Mol Reprod Dev (2003) 0.81

Gene therapy strategies for the treatment of chronic viral hepatitis. Expert Opin Biol Ther (2001) 0.81

Flow cytometry of human semen: a preliminary study of a non-invasive method for the detection of spermatogenetic defects. Hum Reprod (2005) 0.79

Persistent mild hyperphenylalaninemia in various ethnic groups in Israel. Am J Dis Child (1969) 0.79

Spermatogenesis in the golden hamster: the role of c-kit. Mol Reprod Dev (2001) 0.79

Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma. Clin Cancer Res (1998) 0.78

Erythrocyte glyoxalase I polymorphism in several population groups in Israel. Hum Hered (1979) 0.78

Red cell glutathione peroxidase in various Jewish ethnic groups in Israel. Hum Hered (1980) 0.78

Concurrent use of flow cytometry and fluorescence in-situ hybridization techniques for detecting faulty meiosis in a human sperm sample. Mol Hum Reprod (1998) 0.77

Spermiogenesis defects in human: detection of transition proteins in semen from some infertile men. Andrologia (2008) 0.77

Decreased erythrocyte glutathione peroxidase activity in multiple sclerosis. Acta Neurol Scand (1979) 0.76

Liver toxicity induced by combined external-beam irradiation and radioimmunoglobulin therapy. Radiat Res (1995) 0.76

Carnitine and acetylcarnitine in motile and immotile human spermatozoa. Int J Androl (1984) 0.76

Recent highlights from atomic force microscopy of DNA. J Biomol Struct Dyn (2000) 0.76

Glutathione peroxidase activity in various types of blood cells in multiple sclerosis. Acta Neurol Scand (1981) 0.76

Energy expenditure variations in soldiers performing military activities under cold and hot climate conditions. Mil Med (1996) 0.75

In-vitro human spermatozoa nuclear decondensation assessed by flow cytometry. Mol Hum Reprod (1998) 0.75

Cardiovascular responses to beta-blockade and 5 degrees C cold air stress. Can J Physiol Pharmacol (1996) 0.75

A comparative study of spermatozoal chromatin using acridine orange staining and flow cytometry. Comp Biochem Physiol A Mol Integr Physiol (1999) 0.75

Immunochemical study of relationships between erythrocyte glucose-6-phosphate dehydrogenase (G6PD, E.C. 1.1.1.49) of various mammalian species. Comp Biochem Physiol B (1973) 0.75

[Practical pharmacological approach to pain control in advanced cancer]. Harefuah (1993) 0.75

Career plans for male-dominated occupations among female seniors in religious and secular high schools. Adolescence (1992) 0.75

Alkaline phosphatase in human semen: an investigation using enzyme inhibitors and gel electrophoresis. Eur J Clin Chem Clin Biochem (1993) 0.75

Immunological relationships of glyceraldehyde-3-phosphate dehydrogenase, phosphohexose isomerase, aldolase and peptidase from various mammalian species. Comp Biochem Physiol B (1976) 0.75

[Evaluation of sperm samples from infertile men by flow cytometry]. Harefuah (2004) 0.75

Esterase D polymorphism in several population groups in Israel. Hum Hered (1977) 0.75

Procarbazine effects on spermatogenesis in golden hamster: a flow cytometric evaluation. Arch Androl (2002) 0.75

Effects of pivalic acid and sodium pivalate on L-carnitine concentrations in the cauda epididymidis and on male fertility in the hamster. Reprod Fertil Dev (1997) 0.75

Immunochemical study of relationships between erythrocyte glucose-6-phosphate dehydrogenase (G6PD, E.C. 1.1.1.49) of various mammalian species. Comp Biochem Physiol B (1973) 0.75

Immunochemical study of relationships between erythrocyte 6-phosphogluconate dehydrogenase (6PGD), E.C. 1.1.1.44) of various mammalian species. Comp Biochem Physiol B (1974) 0.75

Evaluation of damage to the testicular cells of golden hamsters caused by experimental cryptorchidism using flow cytometry and confocal microscopy. Int J Androl (2003) 0.75

A comparative study of carnitine and acylcarnitine concentration in semen and male reproductive tract fluids. Comp Biochem Physiol B (1982) 0.75

Dual wavelength demultiplexing by coupling and decoupling of photonic crystal waveguides. Opt Express (2004) 0.75

Quantitative enzymatic assay of short-chain acylcarnitines after separation by paper chromatography. Anal Biochem (1980) 0.75

Therapy of peritoneal carcinomatosis of human colon cancer xenografts with yttrium 90-labeled anti-carcinoembryonic antigen antibody ZCE025. Arch Surg (1987) 0.75

Phosphoglycolate phosphatase in several population groups in Israel. Hum Hered (1981) 0.75

Evidence for biological rhythm in spermatogenesis in the pubertal hamster (Mesocricetus auratus): a flow cytometric study. Life Sci (2004) 0.75

Carnitine and short-chain acylcarnitines in the lumen of the human male reproductive tract. Int J Androl (1983) 0.75

Orthodox Jews have a lower incidence of malignant melanoma. A note on the potentially protective role of traditional clothing. Int J Cancer (1993) 0.75

Immunoelectrophoretic-chemical investigation of erythrocyte aspartate aminotransferase. Life Sci (1969) 0.75

Influence of various substrates on the acetylcarnitine:carnitine ratio in motile and immotile human spermatozoa. J Reprod Fertil (1986) 0.75

Immunochemical gel diffusion study of relationships between erythrote catalase of various species. Biochim Biophys Acta (1969) 0.75