Published in Antimicrob Agents Chemother on May 01, 1998
Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev (2001) 15.81
Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother (2004) 10.64
Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae. Antimicrob Agents Chemother (2000) 6.37
CTX-M-5, a novel cefotaxime-hydrolyzing beta-lactamase from an outbreak of Salmonella typhimurium in Latvia. Antimicrob Agents Chemother (1998) 3.74
Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain. Antimicrob Agents Chemother (2000) 3.69
A novel CTX-M beta-lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceae isolated in Brazil. Antimicrob Agents Chemother (2000) 3.47
Molecular epidemiology of the integron-located VEB-1 extended-spectrum beta-lactamase in nosocomial enterobacterial isolates in Bangkok, Thailand. J Clin Microbiol (2001) 3.40
Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China. Antimicrob Agents Chemother (2002) 3.11
CTX-M-type extended-spectrum beta-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop. Antimicrob Agents Chemother (2001) 3.07
Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240-->Gly. Antimicrob Agents Chemother (2001) 3.03
Nucleotide sequence and characterization of a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-10) isolated in Spain. Antimicrob Agents Chemother (2001) 2.91
IBC-1, a novel integron-associated class A beta-lactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain. Antimicrob Agents Chemother (2000) 2.62
Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya. Antimicrob Agents Chemother (2001) 2.39
CTX-M Enzymes: Origin and Diffusion. Front Microbiol (2012) 2.37
Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland. Antimicrob Agents Chemother (2002) 2.29
Salmonella enterica serotype Choleraesuis: epidemiology, pathogenesis, clinical disease, and treatment. Clin Microbiol Rev (2004) 2.26
Identification and expression of cephamycinase bla(CMY) genes in Escherichia coli and Salmonella isolates from food animals and ground meat. Antimicrob Agents Chemother (2001) 2.22
ColE1-like plasmid pIP843 of Klebsiella pneumoniae encoding extended-spectrum beta-lactamase CTX-M-17. Antimicrob Agents Chemother (2002) 2.21
Dissemination of CTX-M-3 and CMY-2 beta-lactamases among clinical isolates of Escherichia coli in southern Taiwan. J Clin Microbiol (2000) 2.11
CTX-M-1, CTX-M-3, and CTX-M-14 beta-lactamases from Enterobacteriaceae isolated in France. Antimicrob Agents Chemother (2002) 2.09
Salmonella enterica serovar virchow with CTX-M-like beta-lactamase in Spain. J Clin Microbiol (2000) 2.04
A novel class A extended-spectrum beta-lactamase (BES-1) in Serratia marcescens isolated in Brazil. Antimicrob Agents Chemother (2000) 1.86
Spread of a Salmonella typhimurium clone resistant to expanded-spectrum cephalosporins in three European countries. J Clin Microbiol (1999) 1.79
Characterization of the first extended-spectrum beta-lactamase-producing Salmonella isolate identified in Canada. J Clin Microbiol (2003) 1.69
Evolution of multiresistance in nontyphoid salmonella serovars from 1984 to 1998 in Argentina. Antimicrob Agents Chemother (2002) 1.64
Early dissemination of CTX-M-derived enzymes in South America. Antimicrob Agents Chemother (2002) 1.61
Plasmidic extended-spectrum beta-lactamases in Vibrio cholerae O1 El Tor isolates in Argentina. Antimicrob Agents Chemother (2002) 1.61
CTX-M-14, a plasmid-mediated CTX-M type extended-spectrum beta-lactamase isolated from Escherichia coli. Antimicrob Agents Chemother (2002) 1.44
TLA-1: a new plasmid-mediated extended-spectrum beta-lactamase from Escherichia coli. Antimicrob Agents Chemother (2000) 1.42
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. Antimicrob Agents Chemother (2010) 1.41
Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria. Crit Rev Microbiol (2012) 1.35
Two different extended-spectrum beta-lactamases (ESBLs) in one of the first ESBL-producing salmonella isolates in Poland. J Clin Microbiol (2002) 1.34
GES extended-spectrum β-lactamases in Acinetobacter baumannii isolates in Belgium. Antimicrob Agents Chemother (2010) 1.29
In vivo acquisition of ceftriaxone resistance in Salmonella enterica serotype anatum. Antimicrob Agents Chemother (2003) 1.21
First isolation of a CTX-M-3-producing Enterobacter cloacae in France. Antimicrob Agents Chemother (2000) 1.21
Role of a mutation at position 167 of CTX-M-19 in ceftazidime hydrolysis. Antimicrob Agents Chemother (2004) 1.10
In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario? Antimicrob Agents Chemother (2011) 1.04
Nosocomial outbreak of infections by Proteus mirabilis that produces extended-spectrum CTX-M-2 type beta-lactamase. J Clin Microbiol (2003) 1.01
Molecular basis for the catalytic specificity of the CTX-M extended-spectrum β-lactamases. Biochemistry (2014) 0.90
Distant and new mutations in CTX-M-1 beta-lactamase affect cefotaxime hydrolysis. Antimicrob Agents Chemother (2011) 0.87
Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases. Antimicrob Agents Chemother (2012) 0.87
Can inhibitor-resistant substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC lead to clavulanate resistance?: a biochemical rationale for the use of β-lactam-β-lactamase inhibitor combinations. Antimicrob Agents Chemother (2013) 0.84
Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. Antimicrob Agents Chemother (2010) 0.81
Comparative Characterization of CTX-M-64 and CTX-M-14 Provides Insights into the Structure and Catalytic Activity of the CTX-M Class of Enzymes. Antimicrob Agents Chemother (2016) 0.79
Transcriptional analysis of the bla(CTX-M-2) gene in Salmonella enterica serovar Infantis. Antimicrob Agents Chemother (2005) 0.77
Noncovalent complexes of an inactive mutant of CTX-M-9 with the substrate piperacillin and the corresponding product. Antimicrob Agents Chemother (2011) 0.77
BetalasEN: microdilution panel for identifying beta-lactamases present in isolates of Enterobacteriaceae. J Clin Microbiol (2002) 0.75
A standard numbering scheme for the class A beta-lactamases. Biochem J (1991) 17.44
A new plasmidic cefotaximase in a clinical isolate of Escherichia coli. Infection (1991) 6.78
Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics. Clin Infect Dis (1997) 6.11
Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics. Antimicrob Agents Chemother (1989) 5.98
Sequences of beta-lactamase genes encoding CTX-M-1 (MEN-1) and CTX-M-2 and relationship of their amino acid sequences with those of other beta-lactamases. Antimicrob Agents Chemother (1996) 5.36
Close amino acid sequence relationship between the new plasmid-mediated extended-spectrum beta-lactamase MEN-1 and chromosomally encoded enzymes of Klebsiella oxytoca. Biochim Biophys Acta (1992) 5.09
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins. Antimicrob Agents Chemother (1991) 5.05
Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure. Antimicrob Agents Chemother (1995) 4.92
Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli. Antimicrob Agents Chemother (1995) 4.81
A new plasmidic cefotaximase from patients infected with Salmonella typhimurium. Infection (1992) 4.52
Cloning and nucleotide sequencing of the gene encoding the beta-lactamase from Citrobacter diversus. FEMS Microbiol Lett (1991) 3.24
Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2). Antimicrob Agents Chemother (1996) 2.74
Cefotaxime-hydrolysing activity of the beta-lactamase of Klebsiella oxytoca D488 could be related to a threonine residue at position 140. FEMS Microbiol Lett (1991) 2.53
Chromosomally encoded cephalosporin-hydrolyzing beta-lactamase of Proteus vulgaris RO104 belongs to Ambler's class A. Biochim Biophys Acta (1994) 2.07
A plasmid-mediated beta-lactamase conferring resistance to cefotaxime in a Salmonella typhimurium clone found in St Petersburg, Russia. J Antimicrob Chemother (1998) 1.79
Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity for aztreonam and ceftazidime. J Biol Chem (1996) 1.63
Replacement of serine 237 in class A beta-lactamase of Proteus vulgaris modifies its unique substrate specificity. Biochemistry (1994) 1.56
Substrate specificities in class A beta-lactamases: preference for penams vs. cephems. The role of residue 237. Proteins (1989) 1.36
CTX-M-type beta-lactamases: an emerging group of extended-spectrum enzymes. Int J Antimicrob Agents (2000) 4.55
VIM-1 Metallo-beta-lactamase-producing Klebsiella pneumoniae strains in Greek hospitals. J Clin Microbiol (2003) 2.98
Transferable cefoxitin resistance in enterobacteria from Greek hospitals and characterization of a plasmid-mediated group 1 beta-lactamase (LAT-2). Antimicrob Agents Chemother (1996) 2.74
Two novel plasmid-mediated cefotaxime-hydrolyzing beta-lactamases (CTX-M-5 and CTX-M-6) from Salmonella typhimurium. FEMS Microbiol Lett (1998) 2.68
IBC-1, a novel integron-associated class A beta-lactamase with extended-spectrum properties produced by an Enterobacter cloacae clinical strain. Antimicrob Agents Chemother (2000) 2.62
Identification of a novel plasmid-mediated beta-lactamase with chromosomal cephalosporinase characteristics from Klebsiella pneumoniae. J Antimicrob Chemother (1993) 2.37
Carbapenem-hydrolysing VIM-2 metallo- beta-lactamase in Pseudomonas aeruginosa from Greece. J Antimicrob Chemother (2000) 2.29
Prevalence of a transferable SHV-5 type beta-lactamase in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Greece. J Antimicrob Chemother (1990) 2.20
Outer membrane alterations in multiresistant mutants of Pseudomonas aeruginosa selected by ciprofloxacin. Antimicrob Agents Chemother (1989) 2.17
Nucleotide sequence of a plasmid-mediated cephalosporinase gene (blaLAT-1) found in Klebsiella pneumoniae. Antimicrob Agents Chemother (1994) 2.13
Emergence of an inhibitor-resistant beta-lactamase (SHV-10) derived from an SHV-5 variant. Antimicrob Agents Chemother (1997) 2.05
Hospital outbreak of multiple clones of Pseudomonas aeruginosa carrying the unrelated metallo-beta-lactamase gene variants blaVIM-2 and blaVIM-4. J Antimicrob Chemother (2003) 1.97
Ongoing epidemic of blaVIM-1-positive Klebsiella pneumoniae in Athens, Greece: a prospective survey. J Antimicrob Chemother (2007) 1.81
Spread of a Salmonella typhimurium clone resistant to expanded-spectrum cephalosporins in three European countries. J Clin Microbiol (1999) 1.79
A plasmid-mediated beta-lactamase conferring resistance to cefotaxime in a Salmonella typhimurium clone found in St Petersburg, Russia. J Antimicrob Chemother (1998) 1.79
Transferable class C beta-lactamases in Escherichia coli strains isolated in Greek hospitals and characterization of two enzyme variants (LAT-3 and LAT-4) closely related to Citrobacter freundii AmpC beta-lactamase. J Antimicrob Chemother (1998) 1.75
An integron-associated beta-lactamase (IBC-2) from Pseudomonas aeruginosa is a variant of the extended-spectrum beta-lactamase IBC-1. J Antimicrob Chemother (2001) 1.60
Sources of diversity of carbapenem resistance levels in Klebsiella pneumoniae carrying blaVIM-1. J Antimicrob Chemother (2006) 1.58
Rare case of failure by an automated system to detect extended-spectrum beta-lactamase in a cephalosporin-resistant Klebsiella pneumoniae isolate. J Clin Microbiol (1999) 1.51
Extended-spectrum beta-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals. Int J Antimicrob Agents (2003) 1.46
Expanded-spectrum cephalosporin resistance in non-typhoid Salmonella. Int J Antimicrob Agents (2004) 1.45
Effect of substitution of Asn for Arg-276 in the cefotaxime-hydrolyzing class A beta-lactamase CTX-M-4. FEMS Microbiol Lett (1998) 1.43
Emergence of resistance to third-generation cephalosporins amongst Salmonella typhimurium isolates in Greece: report of the first three cases. J Antimicrob Chemother (1998) 1.39
Discrepancies and interpretation problems in susceptibility testing of VIM-1-producing Klebsiella pneumoniae isolates. J Clin Microbiol (2005) 1.33
Characterization of a novel SHV beta-lactamase variant that resembles the SHV-5 enzyme. FEMS Microbiol Lett (1996) 1.32
Klebsiella pneumoniae infections in Greek hospitals. Dissemination of plasmids encoding an SHV-5 type beta-lactamase. J Hosp Infect (1995) 1.31
Misidentification of alpha-hemolytic streptococci by routine tests in clinical practice. Infect Genet Evol (2011) 1.31
On the incidence of antibiotic resistance among aerobic gram-negative rods isolated in Greek hospitals. J Hosp Infect (1993) 1.28
CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid. Antimicrob Agents Chemother (2004) 1.26
Spread of integron-associated VIM-type metallo-beta-lactamase genes among imipenem-nonsusceptible Pseudomonas aeruginosa strains in Greek hospitals. J Clin Microbiol (2003) 1.24
Comparative evaluation of the inhibitory activities of the novel penicillanic acid sulfone Ro 48-1220 against beta-lactamases that belong to groups 1, 2b, and 2be. Antimicrob Agents Chemother (1997) 1.22
Quinolone resistance among Escherichia coli strains from community-acquired urinary tract infections in Greece. Clin Microbiol Infect (2004) 1.19
Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element. Antimicrob Agents Chemother (2005) 1.18
Sequence of pNL194, a 79.3-kilobase IncN plasmid carrying the blaVIM-1 metallo-beta-lactamase gene in Klebsiella pneumoniae. Antimicrob Agents Chemother (2010) 1.18
Epidemiologic aspects of male gonococcal infection in Greece. Sex Transm Dis (1999) 1.12
Characterization of In111, a class 1 integron that carries the extended-spectrum beta-lactamase gene blaIBC-1. FEMS Microbiol Lett (2003) 1.10
KPC-producing, multidrug-resistant Klebsiella pneumoniae sequence type 258 as a typical opportunistic pathogen. Antimicrob Agents Chemother (2013) 1.09
High prevalence of stably derepressed class-I beta-lactamase expression in multiresistant clinical isolates of Enterobacter cloacae from Greek hospitals. J Med Microbiol (1992) 1.09
Study of an outbreak of cefoxitin-resistant Klebsiella pneumoniae in a general hospital. J Clin Microbiol (1997) 1.08
Sporadic emergence of Klebsiella pneumoniae strains resistant to cefepime and cefpirome in Greek hospitals. J Clin Microbiol (1998) 1.08
Fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Russia: molecular mechanisms implicated. J Antimicrob Chemother (2004) 1.07
Panresistance in VIM-1-producing Klebsiella pneumoniae. J Antimicrob Chemother (2005) 1.07
Dissemination of cephalosporin-resistant Serratia marcescens strains producing a plasmidic SHV type beta-lactamase in Greek hospitals. Eur J Clin Microbiol Infect Dis (1994) 1.07
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. Antimicrob Agents Chemother (2008) 1.05
Multidrug-resistant strains of Neisseria gonorrhoeae in Greece. Antimicrob Agents Chemother (2001) 1.05
Characterization of metallo-beta-lactamase VIM-27, an A57S mutant of VIM-1 associated with Klebsiella pneumoniae ST147. Antimicrob Agents Chemother (2011) 1.05
Diversity of resistance phenotypes and plasmid analysis in multi-resistant 0:12 Pseudomonas aeruginosa. Eur J Epidemiol (1992) 1.03
Discrimination between Streptococcus pneumoniae and Streptococcus mitis based on sorting of their MALDI mass spectra. Clin Microbiol Infect (2013) 1.03
Imipenem resistance in Enterobacter aerogenes is associated with derepression of chromosomal cephalosporinases and impaired permeability. FEMS Microbiol Lett (1992) 1.02
Identification of OXA-23-producing Acinetobacter baumannii in Greece, 2010 to 2011. Euro Surveill (2012) 1.01
Molecular typing of multidrug-resistant Salmonella Blockley outbreak isolates from Greece. Emerg Infect Dis (2000) 1.01
Methicillin-resistant Staphylococcus aureus in the hospitals of central Greece. Int J Antimicrob Agents (2001) 1.01
[MALDI-ToF mass-spectrometry in analysis of genetically determined resistance of Streptococcus pneumoniae to fluoroquinolones]. Antibiot Khimioter (2007) 1.00
Consecutive mutations leading to the emergence in vivo of imipenem resistance in a clinical strain of Enterobacter aerogenes. J Med Microbiol (1994) 1.00
Emergence of Proteus mirabilis carrying the bla metallo-beta-lactamase gene. Clin Microbiol Infect (2006) 1.00
Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit in the high-prevalence area of Athens, Greece. J Clin Microbiol (2002) 0.98
Repeated occurrence of diverse extended-spectrum beta-lactamases in minor serotypes of food-borne Salmonella enterica subsp. enterica. J Clin Microbiol (2005) 0.96
Detrimental effect of the combination of R164S with G238S in TEM-1 beta-lactamase on the extended-spectrum activity conferred by each single mutation. J Antimicrob Chemother (2000) 0.95
Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases. Antimicrob Agents Chemother (2010) 0.95
Activity of imipenem against VIM-1 metallo-beta-lactamase-producing Klebsiella pneumoniae in the murine thigh infection model. Clin Microbiol Infect (2007) 0.94
CTX-m-3 beta-lactamase-producing Escherichia coli from Greece. Microb Drug Resist (2002) 0.94
Helicobacter pylori infection in spouses of patients with duodenal ulcers and comparison of ribosomal RNA gene patterns. Gut (1996) 0.94
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2010) 0.93