Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force.

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Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells. J Biol Chem (2005) 1.31

Nitric oxide is significantly reduced in ex vivo porcine arteries during reverse flow because of increased superoxide production. J Physiol (2004) 1.31

Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. J Am Heart Assoc (2012) 1.25

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Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation. J Cell Biol (2008) 1.11

NO-mediated regulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells. J Physiol (2006) 1.11

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Diverse roles of the vasculature within the neural stem cell niche. Regen Med (2009) 1.09

Shear stress induces synthetic-to-contractile phenotypic modulation in smooth muscle cells via peroxisome proliferator-activated receptor alpha/delta activations by prostacyclin released by sheared endothelial cells. Circ Res (2009) 1.07

Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells. Proc Natl Acad Sci U S A (2003) 1.07

Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction. Circ J (2011) 1.03

Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity. J Clin Invest (2014) 1.03

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow. Proc Natl Acad Sci U S A (2012) 1.03

Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation. J Clin Invest (2001) 1.00

Analysis of intimal proteoglycans in atherosclerosis-prone and atherosclerosis-resistant human arteries by mass spectrometry. Mol Cell Proteomics (2005) 0.99

p38 MAPK activity is stimulated by vascular endothelial growth factor receptor 2 activation and is essential for shear stress-induced angiogenesis. J Cell Physiol (2010) 0.98

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MEK5 is activated by shear stress, activates ERK5 and induces KLF4 to modulate TNF responses in human dermal microvascular endothelial cells. Microcirculation (2011) 0.95

Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochem Biophys Res Commun (2008) 0.95

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Shear stress and atherosclerosis. Mol Cells (2014) 0.92

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Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress. Antioxid Redox Signal (2009) 0.91

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A model for shear stress sensing and transmission in vascular endothelial cells. Biophys J (2003) 0.90

Force-induced changes in subnuclear movement and rheology. Biophys J (2012) 0.89

JNK2 promotes endothelial cell alignment under flow. PLoS One (2011) 0.89

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Role of biomechanical forces in the natural history of coronary atherosclerosis. Nat Rev Cardiol (2016) 0.89

Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis. Arterioscler Thromb Vasc Biol (2012) 0.88

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Quantitative morphodynamics of endothelial cells within confluent cultures in response to fluid shear stress. Biophys J (2000) 0.87

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Fluid shear, intercellular stress, and endothelial cell alignment. Am J Physiol Cell Physiol (2015) 0.86

Noninvasive assessment of wall-shear rate and vascular elasticity using combined ARFI/SWEI/spectral Doppler imaging system. Ultrason Imaging (2011) 0.85

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A new observation on the stress distribution in the coronary artery wall. J Biomech Eng (2009) 0.84

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