Published in Diabetes on June 01, 1998
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Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care (2015) 1.36
Rapid temporal control of Foxp3 protein degradation by sirtuin-1. PLoS One (2011) 1.31
Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease. Diabetes Care (2015) 1.25
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Moving towards efficient therapies in type 1 diabetes: to combine or not to combine? Autoimmun Rev (2006) 1.09
Progress in immune-based therapies for type 1 diabetes. Clin Exp Immunol (2013) 1.06
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LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes (2005) 0.99
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Immunotherapy for the prevention and treatment of type 1 diabetes: optimizing the path from bench to bedside. Diabetes Care (2009) 0.90
Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases. Arthritis Res (2002) 0.82
Defining populations at risk of rheumatoid arthritis: the first steps to prevention. Nat Rev Rheumatol (2014) 0.78
Lessons from type 1 diabetes for understanding natural history and prevention of autoimmune disease. Rheum Dis Clin North Am (2014) 0.77
Disease modifying therapies in type 1 diabetes: Where have we been, and where are we going? Pharmacol Res (2015) 0.76
Novel diagnostic and therapeutic approaches for autoimmune diabetes--a prime time to treat insulitis as a disease. Clin Immunol (2014) 0.75
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol (2000) 6.57
Self-monitoring of blood glucose in type 2 diabetes and long-term outcome: an epidemiological cohort study. Diabetologia (2005) 5.47
Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet (2000) 3.92
Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N Engl J Med (2001) 3.85
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord (2001) 2.94
High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening. The KORA survey 2000. Diabetologia (2003) 2.73
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Intracellular staining reveals different levels of stratification for on- and off-center ganglion cells in cat retina. J Neurophysiol (1978) 2.19
Rod and cone pathways in the inner plexiform layer of cat retina. Science (1974) 2.12
Human 60-kDa heat-shock protein: a danger signal to the innate immune system. J Immunol (1999) 2.01
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. Nat Med (1999) 1.98
Structural basis for ON-and OFF-center responses in retinal ganglion cells. Science (1976) 1.98
Trend of hip fracture incidence in Germany 1995-2004: a population-based study. Osteoporos Int (2007) 1.90
Prevalence of lipohypertrophy in insulin-treated diabetic patients and predisposing factors. Exp Clin Endocrinol Diabetes (1996) 1.83
Incidence of Type 2 diabetes in the elderly German population and the effect of clinical and lifestyle risk factors: KORA S4/F4 cohort study. Diabet Med (2009) 1.82
A bistratified amacrine cell and synaptic cirucitry in the inner plexiform layer of the retina. Brain Res (1975) 1.80
Human adipocytes secrete mineralocorticoid-releasing factors. Proc Natl Acad Sci U S A (2003) 1.74
Diabetic retinopathy in pediatric patients with type-1 diabetes: effect of diabetes duration, prepubertal and pubertal onset of diabetes, and metabolic control. J Pediatr (1998) 1.72
Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: results of the Fourth International Workshop on the Standardization of Insulin Autoantibody Measurement. J Clin Endocrinol Metab (1992) 1.70
Antimalarial therapy and early retinal changes in patients with rheumatoid arthritis. Br Med J (1966) 1.68
Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation. Lancet (1993) 1.68
Chloroquine retinopathy in the rhesus monkey. Invest Ophthalmol Vis Sci (1978) 1.66
[Quality of care and extent of complications in a population-based sample of patients with type 2 diabetes mellitus. The KORA Survey 2000]. Dtsch Med Wochenschr (2006) 1.64
The inner plexiform layer in the retina of the cat: electron microscopic observations. J Neurocytol (1979) 1.58
Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr Rev (1998) 1.58
Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndrome: a survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG) Br J Haematol (1990) 1.56
Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J Biol Chem (1995) 1.56
Multiple organ failure due to 5-fluorouracil chemotherapy in a patient with a rare dihydropyrimidine dehydrogenase gene variant. Onkologie (2004) 1.54
Mortality in diabetic patients with cardiovascular autonomic neuropathy. Diabet Med (1993) 1.51
Amacrine cells, bipolar cells and ganglion cells of the cat retina: a Golgi study. Vision Res (1981) 1.50
Diabetes classification: grey zones, sound and smoke: Action LADA 1. Diabetes Metab Res Rev (2008) 1.50
[Drug prescriptions and costs in diabetic polyneuropathy]. Dtsch Med Wochenschr (1999) 1.49
Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-alpha or its receptors. Diabetologia (2002) 1.49
The mammalian photoreceptor mosaic-adaptive design. Prog Retin Eye Res (2000) 1.48
Prevalence of autoantibodies to endocrine organs in girls with Ullrich-Turner syndrome aged 5-14 years. Horm Res (1992) 1.46
Milk and type I diabetes. Diabetes Care (1996) 1.45
Self-monitoring of blood glucose in type 2 diabetes: a new look at published trials. Diabetologia (2008) 1.45
Incidence of lower-limb amputations in the diabetic compared to the non-diabetic population. findings from nationwide insurance data, Germany, 2005-2007. Exp Clin Endocrinol Diabetes (2009) 1.45
Introducing a simplified approach to insulin therapy in type 2 diabetes: a comparison of two single-dose regimens of insulin glulisine plus insulin glargine and oral antidiabetic drugs. Diabetes Obes Metab (2008) 1.45
Histochemical demonstration of glycogen in neurons of the cat retina. Invest Ophthalmol Vis Sci (1996) 1.43
Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. Diabetes (2000) 1.43
Molecular mechanisms of insulin resistance. Diabet Med (2005) 1.42
Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem Biophys Res Commun (1991) 1.42
Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies. Horm Metab Res (2008) 1.41
Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes. Diabetologia (2003) 1.41
Long-term experience with an ultrapure individual dialysis fluid with a batch type machine. Nephrol Dial Transplant (1998) 1.40
[Progress in molecular medicine: "laser capture microdissection"]. Med Klin (Munich) (1998) 1.39
[Model trial: use and evaluation of a problem-oriented learning program in internal medicine]. Med Klin (Munich) (1999) 1.39
Response to Hex et al. Estimating the current and future costs of Type 1 and Type 2 diabetes in the UK, including direct health costs and indirect societal and productivity costs. Diabet Med (2013) 1.39
Prevalence of undiagnosed diabetes and impaired glucose regulation in 35-59-year-old individuals in Southern Germany: the KORA F4 Study. Diabet Med (2010) 1.37
Electron microscopic observations of human retinitis pigmentosa, dominantly inherited. Invest Ophthalmol (1974) 1.35
Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes (1996) 1.33
Macrophage infiltration precedes and is a prerequisite for lymphocytic insulitis in pancreatic islets of pre-diabetic BB rats. Diabetologia (1989) 1.32
Autoantibodies to vasopressin cells in idiopathic diabetes insipidus: evidence for an autoimmune variant. Lancet (1983) 1.31
Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J Clin Invest (1997) 1.31
Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study. Diabetologia (2009) 1.30
IL-1 and IFN-gamma increase vascular permeability. Immunology (1988) 1.29
Identification of a subtype of cone photoreceptor, likely to be blue sensitive, in the human retina. J Comp Neurol (1987) 1.29
Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM. Diabetes (1992) 1.28
Chemokines as risk factors for type 2 diabetes: results from the MONICA/KORA Augsburg study, 1984-2002. Diabetologia (2006) 1.28
Sex differences in the associations of socioeconomic status with undiagnosed diabetes mellitus and impaired glucose tolerance in the elderly population: the KORA Survey 2000. Eur J Public Health (2005) 1.26
A17: a broad-field amacrine cell in the rod system of the cat retina. J Neurophysiol (1985) 1.25
Projection of the burden of type 2 diabetes mellitus in Germany: a demographic modelling approach to estimate the direct medical excess costs from 2010 to 2040. Diabet Med (2013) 1.24
Temporal, seasonal, and geographical incidence patterns of type I diabetes mellitus in children under 5 years of age in Germany. Diabetologia (1999) 1.24
Altered chemokine levels in individuals at risk of Type 1 diabetes mellitus. Diabet Med (2006) 1.23
Administration of silica prevents diabetes in BB-rats. Diabetes (1985) 1.22
Natural history and treatment of low and high risk superficial bladder tumors. J Urol (1988) 1.22
Heat shock protein hsp70 overexpression confers resistance against nitric oxide. FEBS Lett (1996) 1.21
Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion. Biochem Biophys Res Commun (1994) 1.21
Treatment persistence, hypoglycaemia and clinical outcomes in type 2 diabetes patients with dipeptidyl peptidase-4 inhibitors and sulphonylureas: a primary care database analysis. Diabetes Obes Metab (2012) 1.20
Synaptic patterns and response properties of bipolar and ganglion cells in the cat retina. Vision Res (1983) 1.20
The organization of the outer plexiform layer in the retina of the cat: electron microscopic observations. J Neurocytol (1977) 1.19
Low-dose streptozocin-induced diabetes in mice. Electron microscopy reveals single-cell insulitis before diabetes onset. Diabetes (1988) 1.19
The localization of guanylyl cyclase-activating proteins in the mammalian retina. Invest Ophthalmol Vis Sci (1998) 1.19
The connections between bipolar cells and photoreceptors in the retina of the domestic cat. J Comp Neurol (1973) 1.18
Activated and interferon-gamma producing thyroid-derived T cells are detected in Graves' disease, thyroid autonomy as well as in non-toxic multinodular goiter. Eur J Endocrinol (1996) 1.16
Mouse models of insulin dependent diabetes: low-dose streptozocin-induced diabetes and nonobese diabetic (NOD) mice. Diabetes Metab Rev (1987) 1.15
Comparison of octreotide acetate LAR and lanreotide SR in patients with acromegaly. Clin Endocrinol (Oxf) (2000) 1.15
Galactose-specific receptors on liver cells. II. Characterization of the purified receptor from macrophages reveals no structural relationship to the hepatocyte receptor. Biochim Biophys Acta (1985) 1.15
Antibodies against glutamic acid decarboxylase: prevalence in neurological diseases. J Neurol Neurosurg Psychiatry (2001) 1.14
Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a nondiabetic patient with multiple autoantibodies and Graves' disease: a comparison with those present in type 1 diabetes. J Clin Endocrinol Metab (1997) 1.14
Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland: leptin inhibits cortisol release directly. Diabetes (1997) 1.14
Interleukin-6 and the interleukin-6 receptor in the human adrenal gland: expression and effects on steroidogenesis. J Clin Endocrinol Metab (1997) 1.14
Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide. Biochim Biophys Acta (1993) 1.13
Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease. Diabetes (1997) 1.13
Circulating forms of intercellular adhesion molecule (ICAM)-1 in mice lacking membranous ICAM-1. Blood (2000) 1.13
Gene array and expression of mouse retina guanylate cyclase activating proteins 1 and 2. Invest Ophthalmol Vis Sci (1998) 1.12
Presence of a lectin-like receptor for D-galactose on rat peritoneal macrophages. FEBS Lett (1980) 1.11
HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus. Eur J Immunol (1996) 1.11