Published in Biochim Biophys Acta on April 17, 1998
Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study. Proc Natl Acad Sci U S A (2000) 3.74
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J (1999) 2.64
14-3-3 sigma positively regulates p53 and suppresses tumor growth. Mol Cell Biol (2003) 1.93
Aurora B kinase phosphorylates and instigates degradation of p53. Proc Natl Acad Sci U S A (2012) 1.66
Excess beta-catenin promotes accumulation of transcriptionally active p53. EMBO J (1999) 1.63
Critical contribution of the MDM2 acidic domain to p53 ubiquitination. Mol Cell Biol (2003) 1.49
Roles of COP9 signalosome in cancer. Cell Cycle (2011) 1.37
MDM2 and MDMX: Alone and together in regulation of p53. Transl Cancer Res (2012) 1.00
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression. Mol Cell Biol (2008) 0.99
Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Dev Biol (2011) 0.92
HDM2-binding partners: interaction with translation elongation factor EF1alpha. J Proteome Res (2007) 0.84
Bradykinin B2 receptor null mice harboring a Ser23-to-Ala substitution in the p53 gene are protected from renal dysgenesis. Am J Physiol Renal Physiol (2008) 0.80
The MDM2-p53 pathway: multiple roles in kidney development. Pediatr Nephrol (2014) 0.80
MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation. PLoS One (2015) 0.79
Sequence-specific 1H, 15N, and 13C assignment of the N-terminal domain of the human oncoprotein MDM2 that binds to p53. J Biomol NMR (2000) 0.77
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev (1997) 1.88
High metastatic potential in mice inheriting a targeted p53 missense mutation. Proc Natl Acad Sci U S A (2000) 1.73
mdm2 deletion does not alter growth characteristics of p53-deficient embryo fibroblasts. Oncogene (1996) 1.40
Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice. J Pathol (1999) 1.32
The cenpB gene is not essential in mice. Chromosoma (1998) 1.17
Cyclin E restores p53 activity in contact-inhibited cells. Mol Cell Biol (1995) 0.83
Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality. Nat Genet (1997) 0.81