Published in Curr Opin Genet Dev on April 01, 1998
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell (2001) 6.39
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol Cell Biol (2001) 6.05
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev (2000) 5.72
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev (2001) 4.28
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev (2000) 3.40
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes. Nucleic Acids Res (2000) 3.16
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Mol Cell Biol (2000) 2.62
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci U S A (1999) 2.51
DNA damage checkpoint in budding yeast. EMBO J (1998) 2.25
Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. EMBO J (1998) 2.18
Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J (2000) 2.15
Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage. Genes Dev (1999) 2.14
Mitotic DNA damage and replication checkpoints in yeast. Curr Opin Cell Biol (1998) 2.11
RB-dependent S-phase response to DNA damage. Mol Cell Biol (2000) 2.08
RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. EMBO J (1999) 2.05
DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints. Mol Cell Biol (2000) 1.98
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage. EMBO Rep (2003) 1.96
p53 down-regulates CHK1 through p21 and the retinoblastoma protein. Mol Cell Biol (2001) 1.93
Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell (2000) 1.93
Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85
Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities. Mol Cell Biol (2004) 1.78
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. EMBO J (2004) 1.65
NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.59
Rfc4 interacts with Rpa1 and is required for both DNA replication and DNA damage checkpoints in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.58
Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics (2002) 1.51
Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast. Mol Cell Biol (2001) 1.48
Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.46
Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints. Mol Biol Cell (1999) 1.46
Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol (2003) 1.37
The pachytene checkpoint in Saccharomyces cerevisiae requires the Sum1 transcriptional repressor. EMBO J (2000) 1.30
Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break. Mol Cell Biol (2003) 1.24
EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae. Genetics (2000) 1.23
RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae. Genetics (1999) 1.21
DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts. Biochem J (2000) 1.21
Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint. Mol Cell Biol (2001) 1.18
Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku. Mol Cell Biol (2002) 1.14
A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint. Genes Dev (2002) 1.14
Silent repair accounts for cell cycle specificity in the signaling of oxidative DNA lesions. EMBO J (2001) 1.11
Meiotic DNA replication checkpoint control in fission yeast. Genes Dev (1999) 1.09
A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase. Mol Cell Biol (2002) 1.08
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage. Proc Natl Acad Sci U S A (2001) 1.08
Structure-function analysis of fission yeast Hus1-Rad1-Rad9 checkpoint complex. Mol Biol Cell (2001) 1.05
A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. J Mol Biol (2010) 1.04
Mitotic death: a mechanism of survival? A review. Cancer Cell Int (2001) 1.02
The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4. Genes Dev (2001) 0.98
A haploid-specific transcriptional response to irradiation in Saccharomyces cerevisiae. Nucleic Acids Res (2005) 0.97
Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications. DNA Repair (Amst) (2008) 0.96
Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide. Mol Biol Cell (2001) 0.95
Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae. Genetics (2000) 0.93
Immunodeficiency associated with DNA repair defects. Clin Exp Immunol (2000) 0.91
A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A (2002) 0.89
Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage. Nucleic Acids Res (2006) 0.88
Meiotic S-phase damage activates recombination without checkpoint arrest. Mol Biol Cell (2005) 0.85
H2AX foci in late S/G2- and M-phase cells after hydroxyurea- and aphidicolin-induced DNA replication stress in Vicia. Histochem Cell Biol (2007) 0.84
Kinetochores prevent repair of UV damage in Saccharomyces cerevisiae centromeres. Mol Cell Biol (2004) 0.83
DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics (2000) 0.83
Homologous recombination is essential for RAD51 up-regulation in Saccharomyces cerevisiae following DNA crosslinking damage. Nucleic Acids Res (2002) 0.81
Mpg1, a fission yeast protein required for proper septum structure, is involved in cell cycle progression through cell-size checkpoint. Mol Genet Genomics (2005) 0.81
A novel method to identify cooperative functional modules: study of module coordination in the Saccharomyces cerevisiae cell cycle. BMC Bioinformatics (2011) 0.79
Targeting ATM-deficient CLL through interference with DNA repair pathways. Front Genet (2015) 0.78
Yeast RAD2, a homolog of human XPG, plays a key role in the regulation of the cell cycle and actin dynamics. Biol Open (2014) 0.75
Yeast as a model system to study metabolic impact of selenium compounds. Microb Cell (2015) 0.75
Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. Genetics (2017) 0.75
4-Hydroxy TEMPO attenuates dichlorvos induced microglial activation and apoptosis. ACS Chem Neurosci (2014) 0.75