PubRank

P Crine

Author PubWeight™ 90.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Properties of the endonuclease for depurinated DNA from Escherichia coli. Can J Biochem 1972 1.57
2 Expression of neutral endopeptidase (enkephalinase) in heterologous COS-1 cells. Characterization of the recombinant enzyme and evidence for a glutamic acid residue at the active site. J Biol Chem 1988 1.40
3 Enzyme replacement therapy prevents dental defects in a model of hypophosphatasia. J Dent Res 2011 1.30
4 Developmental expression and tissue distribution of Phex protein: effect of the Hyp mutation and relationship to bone markers. J Bone Miner Res 2000 1.30
5 Exploration of the catalytic site of endopeptidase 24.11 by site-directed mutagenesis. Histidine residues 583 and 587 are essential for catalysis. FEBS Lett 1988 1.29
6 Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism. Peptides 1995 1.26
7 Abundance of sarcoplasmic reticulum calcium pump isoforms in stomach and cardiac muscles. Biochem J 1990 1.16
8 Concomitant synthesis of beta-endorphin and alpha-melanotropin from two forms of pro-opiomelanocortin in the rat pars intermedia. Proc Natl Acad Sci U S A 1979 1.13
9 Biosynthesis of beta-endorphin from beta-lipotropin and a larger molecular weight precursor in rat pars intermedia. Proc Natl Acad Sci U S A 1978 1.11
10 Identification of glutamic acid 646 as a zinc-coordinating residue in endopeptidase-24.11. J Biol Chem 1991 1.08
11 In vitro biosynthesis and chemical characterization of beta-lipotropin, gamma-lipotropin, and beta-endorphin in rat pars intermedia. Proc Natl Acad Sci U S A 1978 1.07
12 Primary structure homologies between two zinc metallopeptidases, the neutral endopeptidase 24.11 ("enkephalinase") and thermolysin, through clustering analysis. Biochemistry 1988 1.07
13 Pex mRNA is localized in developing mouse osteoblasts and odontoblasts. J Histochem Cytochem 1998 1.06
14 Immediate inactivation of T7 coliphage treated by monofunctional alkylating agents. Biochim Biophys Acta 1974 1.06
15 Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells. J Biol Chem 1989 1.05
16 Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11). J Biol Chem 1991 1.02
17 In vitro repair of apurinic sites in DNA. Proc Natl Acad Sci U S A 1974 1.00
18 The production and characterization of a monoclonal antibody specific for the 94,000 dalton enkephalin-degrading peptidase from rabbit kidney brush border. Biochem Biophys Res Commun 1985 1.00
19 From beta-lipotropin to beta-endorphin and 'pro-opio-melanocortin'. Can J Biochem 1979 0.99
20 Antibodies specific to the plasma membrane of rat lung microvascular endothelium. Exp Cell Res 1997 0.98
21 Determination of single-strand breaks in DNA using neutral sucrose gradients. Anal Biochem 1976 0.98
22 The yeast KEX-2-processing endoprotease is active in the Golgi apparatus of transfected NIH 3T3 fibroblasts. Mol Endocrinol 1990 0.96
23 Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family. Biochem J 2000 0.94
24 Isolation and partial characterization of a biosynthetic N-terminal methionyl peptide of bovine pars intermedia: relationship to ubiquitin. Biochem Biophys Res Commun 1978 0.93
25 In vitro biosynthesis of beta-endorphin, gamma-lipoprotein, and beta-lipotropin by the pars intermedia of beef pituitary glands. Proc Natl Acad Sci U S A 1977 0.93
26 Expression and polarized apical secretion in Madin-Darby canine kidney cells of a recombinant soluble form of neutral endopeptidase lacking the cytosolic and transmembrane domains. J Biol Chem 1992 0.93
27 The use of a monoclonal antibody for the rapid purification of kidney neutral endopeptidase ("enkephalinase") solubilized in octyl glucoside. Biochem Cell Biol 1987 0.92
28 Asp650 is crucial for catalytic activity of neutral endopeptidase 24-11. Eur J Biochem 1994 0.92
29 In vitro biosynthesis of beta-endorphin in pituitary glands. Proc Natl Acad Sci U S A 1977 0.91
30 Expression of porcine pro-opiomelanocortin cDNA in heterologous monkey kidney cells. Biosynthesis and secretion of the prohormone without processing. J Biol Chem 1987 0.90
31 Proteolytic processing of the alpha-subunit of rat endopeptidase-24.18 by furin. Biochem J 1995 0.90
32 Recombinant human endothelin-converting enzyme ECE-1b is located in an intracellular compartment when expressed in polarized Madin-Darby canine kidney cells. Biochem J 1998 0.90
33 Characterization of PHEX endopeptidase catalytic activity: identification of parathyroid-hormone-related peptide107-139 as a substrate and osteocalcin, PPi and phosphate as inhibitors. Biochem J 2001 0.89
34 Rat endopeptidase-24.18 alpha subunit is secreted into the culture medium as a zymogen when expressed by COS-1 cells. FEBS Lett 1993 0.89
35 Expression of rat endopeptidase-24.18 in COS-1 cells: membrane topology and activity. Biochem J 1994 0.88
36 Kinetic evidence that His-711 of neutral endopeptidase 24.11 is involved in stabilization of the transition state. FEBS Lett 1993 0.88
37 Polarized distribution of neutral endopeptidase 24.11 at the cell surface of cultured human intestinal epithelial Caco-2 cells. Biochem J 1992 0.88
38 Neutral endopeptidase, a major brush border protein of the kidney proximal nephron, is directly targeted to the apical domain when expressed in Madin-Darby canine kidney cells. J Biol Chem 1991 0.88
39 Molecular cloning, tissue distribution, and chromosomal localization of MMEL2, a gene coding for a novel human member of the neutral endopeptidase-24.11 family. DNA Cell Biol 2001 0.87
40 Partial N-terminal amino acid sequence of pro-opio-melanocortin (ACTH/beta-LPH precursor) from rat pars intermedia. Biochem Biophys Res Commun 1980 0.87
41 Processing of two forms of the common precursor to alpha-melanotropin and beta-endorphin in the rat pars intermedia. Evidence for and partial characterization of new pituitary peptides. Eur J Biochem 1980 0.87
42 A cleavable N-terminal signal peptide is not a prerequisite for the biosynthesis of glycosylphosphatidylinositol-anchored proteins. J Biol Chem 1994 0.86
43 Evidence that Asn542 of neprilysin (EC 3.4.24.11) is involved in binding of the P2' residue of substrates and inhibitors. Biochem J 1995 0.86
44 Transformation of the signal peptide/membrane anchor domain of a type II transmembrane protein into a cleavable signal peptide. J Biol Chem 1993 0.86
45 Cellular localization of neprilysin in mouse bone tissue and putative role in hydrolysis of osteogenic peptides. J Bone Miner Res 2000 0.86
46 Expression of variant forms of proopiomelanocortin, the common precursor to corticotropin and beta-lipotropin in the rat pars intermedia. Biochemistry 1981 0.85
47 Molecular cloning of the alpha-subunit of rat endopeptidase-24.18 (endopeptidase-2) and co-localization with endopeptidase-24.11 in rat kidney by in situ hybridization. FEBS Lett 1992 0.85
48 Recombinant neutral endopeptidase-24.11 expressed in mouse neuroblastoma cells is associated with neurite membranes. Biochem J 1990 0.85
49 Monoclonal antibodies as probes for the transmembrane structure of neutral endopeptidase 24.11 ('enkephalinase'). Biochim Biophys Acta 1988 0.85
50 Expression of porcine pro-opiomelanocortin in mouse neuroblastoma (Neuro2A) cells: targeting of the foreign neuropeptide to dense-core vesicles. Mol Cell Endocrinol 1991 0.85
51 Direct targeting of neutral endopeptidase (EC 3.4.24.11) to the apical cell surface of transfected LLC-PK1 cells and unpolarized secretion of its soluble form. Biochem J 1995 0.84
52 Intracellular proteolytic processing of proopiomelanocortin in heterologous COS-1 cells by the yeast KEX2 endoprotease. Biochem Cell Biol 1990 0.84
53 Secretion of a functional soluble form of neutral endopeptidase-24.11 from a baculovirus-infected insect cell line. Biochem J 1992 0.84
54 Effects of monensin on the processing of pro-opiomelanocortin in the intermediate lobe of the rat pituitary. Biochem Biophys Res Commun 1982 0.84
55 Complete sequence of rabbit kidney aminopeptidase N and mRNA localization in rabbit kidney by in situ hybridization. Biochem Cell Biol 1994 0.84
56 Investigation of a possible role of the amino-terminal pro-region of proopiomelanocortin in its processing and targeting to secretory granules. Mol Cell Endocrinol 1991 0.84
57 Role of glycosylation in transport and enzymic activity of neutral endopeptidase-24.11. Biochem J 1994 0.83
58 Comparative analysis of neutral endopeptidase (NEP) and villin gene expression during mouse embryogenesis and enterocyte maturation. Differentiation 1994 0.83
59 A betaLPH precursor model: recent developments concerning morphine-like substances. Ann N Y Acad Sci 1977 0.83
60 Insertion of hydrophilic amino acid residues in the signal peptide/membrane anchor domain of neprilysin (neutral endopeptidase-24.11) results in its cleavage: role of the position of insertion. Arch Biochem Biophys 1994 0.83
61 Substitution of potential metal-coordinating amino acid residues in the zinc-binding site of endopeptidase-24.11. FEBS Lett 1993 0.82
62 Localization of neprilysin (EC 3.4.24.11) mRNA in rat brain by in situ hybridization. J Neurosci Res 1993 0.82
63 Biosynthesis of a putative gonadotropin receptor component by rat leydig cells: isolation of a radiolabeled acidic protein of 79,000 molecular weight by affinity chromatography. Endocrinology 1982 0.81
64 Trophic and tropic effects of striatal astrocytes on cografted mesencephalic dopamine neurons and their axons. J Neurosci Res 1998 0.81
65 Bradykinin metabolism in the postinfarcted rat heart: role of ACE and neutral endopeptidase 24.11. Am J Physiol 1999 0.81
66 Endopeptidase-24.11 is suppressed in myelin-forming but not in non-myelin-forming Schwann cells during development of the rat sciatic nerve. Neuroscience 1992 0.81
67 Secretion of a type II integral membrane protein induced by mutation of the transmembrane segment. Biochem J 1997 0.81
68 Targeting and processing of pro-opiomelanocortin in neuronal cell lines. J Neurochem 1989 0.81
69 Type VI membrane proteins? Trends Biochem Sci 1996 0.80
70 Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11. J Biol Chem 1992 0.80
71 Interaction of mammalian neprilysin with binding protein and calnexin in Schizosaccharomyces pombe. Biochem J 1999 0.80
72 A novel, 85 kDa endothelial antigen differentiates plasma membrane macrodomains in lung alveolar capillaries. Endothelium 1999 0.80
73 Increased functional differentiation of rabbit proximal tubule cells cultured in glucose-free media. Am J Physiol 1992 0.80
74 Post-translational incorporation of [35S]sulfate into oligosaccharide side chains of pro-opiomelanocortin in rat intermediate lobe cells. J Biol Chem 1985 0.80
75 Screening of monoclonal antibodies for hCG for affinity and specificity. Biochem Cell Biol 1988 0.80
76 Identification and characterization of aminopeptidases from Aplysia californica. Biochem J 1992 0.79
77 Incorporation of canavanine into rat pars intermedia proteins inhibits the maturation of pro-opiomelanocortin, the common precursor to adrenocorticotropin and beta-lipotropin. J Biol Chem 1982 0.79
78 Expression of an enzymically active glycosylphosphatidylinositol-anchored form of neutral endopeptidase (EC 3.4.24.11) in Cos-1 cells. Biochem J 1994 0.79
79 Differential expression of neuropeptide gene mRNA within the LUQ cells of Aplysia californica. J Neurobiol 1992 0.79
80 Development of [125I]RB104, a potent inhibitor of neutral endopeptidase 24.11, and its use in detecting nanogram quantities of the enzyme by "inhibitor gel electrophoresis". Proc Natl Acad Sci U S A 1992 0.79
81 Beta-lipotropin precursor of beta-MSH and beta-endorphin. Ann Nutr Aliment 1979 0.78
82 Targeting of pro-opiomelanocortin to the regulated secretory pathway may involve cooperation between different protein domains. Mol Cell Endocrinol 1993 0.78
83 The N-terminal segment of endothelin-converting enzyme (ECE)-1b contains a di-leucine motif that can redirect neprilysin to an intracellular compartment in Madin-Darby canine kidney (MDCK) cells. Biochem J 1999 0.78
84 Inhibitors of neprilysin: design, pharmacological and clinical applications. Methods Enzymol 1995 0.78
85 Identification and characterization of a neutral endopeptidase activity in Aplysia californica. Biochem J 1993 0.78
86 Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin. Biochem J 1996 0.78
87 Neutral endopeptidase (EC 3.4.24.11): constructed molecular forms show new angles of an old enzyme. Biochem Cell Biol 1995 0.77
88 Predominant basolateral proteolytic processing of prosomatostatin into somatostatin-28 in polarized LLC-PK1 cells. Neuropeptides 1997 0.77
89 Biosynthesis and polarized distribution of neutral endopeptidase in primary cultures of kidney proximal tubule cells. Biochem J 1994 0.77
90 The nature of topogenic sequences determines the transport competence of topological mutants of neutral endopeptidase-24.11. Biochem J 1995 0.77
91 Role of the glycosyl-phosphatidylinositol anchor in the intracellular transport of a transmembrane protein in Madin-Darby canine kidney cells. Biochim Biophys Acta 1998 0.77
92 Two large glycoprotein fragments related to the NH2-terminal part of the adrenocorticotropin-beta-lipotropin precursor are the end products of the maturation process in the rat pars intermedia. Can J Biochem 1980 0.77
93 Posttranslational modifications of proopiomelanocortin in rat intermediate lobe cells. Biochem Cell Biol 1986 0.77
94 Chemical characterization of rat alpha MSH/beta-endorphin precursor from pars intermedia. Ann N Y Acad Sci 1980 0.77
95 Characterization of neutral endopeptidase 24.11 in dog glomeruli. Biochem J 1993 0.77
96 Production of monoclonal antibodies against the N-terminal glycopeptide of porcine pro-opiomelanocortin: their use for solid-phase radioimmunoassay, western blotting, and immunogold cytochemistry. Biochem Cell Biol 1991 0.76
97 Irreversible photolabeling of active site of neutral endopeptidase-24.11 "enkephalinase" by azidothiorphan and [14C]-azidothiorphan. Mol Pharmacol 1987 0.76
98 A study of DNA spontaneous degradation. Biochim Biophys Acta 1976 0.76
99 Incorporation of radiolabeled amino acids into protein subunits of the rat leydig cell gonadotropin receptor: application to the study of receptor structure and turnover. Ann N Y Acad Sci 1984 0.76
100 Identification of Glu 646 of neutral endopeptidase 24-11 as a zinc binding residue. Matrix Suppl 1992 0.75
101 Identification of two arginine residues involved in the binding of substrate to neutral endopeptidase 24-11. Matrix Suppl 1992 0.75
102 Fate of a fluorescent inhibitor of endopeptidase-24.11 using enzyme-expressing MDCK cells. Modification of its cellular processing with a monoclonal antibody. Eur J Cell Biol 1994 0.75
103 The addition of a glycosyl-phosphatidylinositol-anchor to a soluble form of neutral endopeptidase re-establishes its apical targeting in LLC-PK1 cells. Biochem Soc Trans 1996 0.75
104 Biosynthesis of a ubiquitin-related peptide in rat brain and in human and mouse pituitary tumors. Biochem Biophys Res Commun 1978 0.75
105 [In vitro biosynthesis of beta-lipotropin in brain tissue]. C R Seances Acad Sci D 1979 0.75
106 [Biosynthesis of beta-endorphin]. Bull Schweiz Akad Med Wiss 1978 0.75
107 Biosynthesis of beta-endorphin, beta-lipotropin and the putative ACTH-LPH precursor in the frog pars intermedia. Life Sci 1978 0.75
108 Characterisation of neprilysin (EC 3.4.24.11) S2' subsite. FEBS Lett 1997 0.75
109 Effects of the monovalent ionophore monensin on the intracellular transport and processing of pro-opiomelanocortin in cultured intermediate lobe cells of the rat pituitary. J Biol Chem 1984 0.75
110 Determination of brush border membrane vesicle orientation using monoclonal antibodies recognizing extracytoplasmic and cytoplasmic domains of neutral endopeptidase-24.11. Anal Biochem 1988 0.75
111 New perspectives in neuropeptides. Biosynthesis from large precursors. The pro-opio-melanocortin model in the pars intermedia. Acta Psychiatr Belg 1981 0.75
112 Presence of endopeptidase 24.11 during the ontogeny of the small intestine in different species. Biol Neonate 1989 0.75
113 Expression of porcine pro-opiomelanocortin cDNA in an established fibroblastic cell line: constitutive secretion of the precursor without proteolytic processing. Mol Cell Endocrinol 1988 0.75
114 Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures. Arch Biochem Biophys 2001 0.75
115 Characterization of sulfated forms of the pro-opiomelanocortin amino-terminal glycopeptide in rat intermediate lobe cells. Peptides 1986 0.75
116 Structure and maturation process of pro-opiomelanocortin: a model for other neuropeptides. Adv Biochem Psychopharmacol 1980 0.75
117 [Biosynthesis of polypeptide hormones]. Rev Can Biol 1980 0.75
118 Role of the glycosyl-phosphatidylinositol anchor in membrane protein sorting in Madin-Darby canine kidney cells. Biochem Soc Trans 1996 0.75