Published in J Virol on August 01, 1998
Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans. J Virol (2000) 3.88
Antigen-driven effector CD8 T cell function regulated by T-bet. Proc Natl Acad Sci U S A (2003) 3.23
Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungs. J Exp Med (2001) 3.19
Critical role of IL-17RA in immunopathology of influenza infection. J Immunol (2009) 2.51
Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms. J Clin Invest (2012) 1.95
The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice. J Virol (2000) 1.81
Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms. J Virol (2010) 1.72
Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles. Virology (2010) 1.39
Whole inactivated virus influenza vaccine is superior to subunit vaccine in inducing immune responses and secretion of proinflammatory cytokines by DCs. Influenza Other Respir Viruses (2008) 1.33
Repeated stimulation of CD4 effector T cells can limit their protective function. J Exp Med (2005) 1.31
CC chemokine receptor 7 expression by effector/memory CD4+ T cells depends on antigen specificity and tissue localization during influenza A virus infection. J Virol (2004) 1.23
A single E627K mutation in the PB2 protein of H9N2 avian influenza virus increases virulence by inducing higher glucocorticoids (GCs) level. PLoS One (2012) 1.21
Hallmarks of CD4 T cell immunity against influenza. J Intern Med (2011) 1.19
Evasion of influenza A viruses from innate and adaptive immune responses. Viruses (2012) 1.06
Gamma interferon is not required for mucosal cytotoxic T-lymphocyte responses or heterosubtypic immunity to influenza A virus infection in mice. J Virol (2000) 1.03
Role of interleukin-4 (IL-4), IL-12, and gamma interferon in primary and vaccine-primed immune responses to Friend retrovirus infection. J Virol (2001) 1.01
Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production. J Immunol (2015) 1.01
Innate immune evasion strategies of influenza viruses. Future Microbiol (2010) 1.00
Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults. Eur J Immunol (2012) 0.94
Development of cross-protective influenza a vaccines based on cellular responses. Front Immunol (2015) 0.88
A VLP vaccine induces broad-spectrum cross-protective antibody immunity against H5N1 and H1N1 subtypes of influenza A virus. PLoS One (2012) 0.88
Immunodominant CD4+ T-cell responses to influenza A virus in healthy individuals focus on matrix 1 and nucleoprotein. J Virol (2014) 0.87
Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus. PLoS One (2008) 0.84
Memory CD4 T cells in influenza. Curr Top Microbiol Immunol (2015) 0.83
Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens. J Virol (2003) 0.83
Influenza vaccine induces intracellular immune memory of human NK cells. PLoS One (2015) 0.82
Influenza virus vaccination induces interleukin-12/23 receptor beta 1 (IL-12/23R beta 1)-independent production of gamma interferon (IFN-gamma) and humoral immunity in patients with genetic deficiencies in IL-12/23R beta 1 or IFN-gamma receptor I. Clin Vaccine Immunol (2008) 0.81
Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge. Viral Immunol (2014) 0.80
The effector T cell response to influenza infection. Curr Top Microbiol Immunol (2015) 0.79
Heterosubtypic T-Cell Immunity to Influenza in Humans: Challenges for Universal T-Cell Influenza Vaccines. Front Immunol (2016) 0.79
Inflammatory impact of IFN-γ in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways. Am J Physiol Lung Cell Mol Physiol (2015) 0.79
Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients. Transplantation (2014) 0.78
Immune Responses to Influenza Virus and Its Correlation to Age and Inherited Factors. Front Microbiol (2016) 0.75
Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science (1993) 14.91
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol (1986) 10.92
Heterologous protection against influenza by injection of DNA encoding a viral protein. Science (1993) 10.14
Biological properties of an influenza A virus-specific killer T cell clone. Inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions. J Exp Med (1981) 5.82
Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med (1993) 4.94
Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor. J Exp Med (1994) 4.91
Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells. J Immunol (1990) 4.83
Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase. Science (1993) 4.80
Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance. J Exp Med (1990) 3.45
Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J Clin Invest (1983) 3.32
Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol (1991) 3.12
HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin. Nature (1987) 2.96
Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. J Exp Med (1986) 2.89
Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J Exp Med (1993) 2.88
Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice. J Virol (1995) 2.70
Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. J Exp Med (1997) 2.67
Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J Exp Med (1994) 2.53
The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections. J Virol (1995) 2.45
Glycosylation of neuraminidase determines the neurovirulence of influenza A/WSN/33 virus. J Virol (1993) 2.40
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proc Natl Acad Sci U S A (1995) 2.33
Interferon-gamma: biology and role in pathogenesis. Adv Immunol (1996) 2.08
Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein. J Leukoc Biol (1995) 1.63
The recovery of mice from influenza virus infection: adoptive transfer of immunity with immune T lymphocytes. Scand J Immunol (1978) 1.62
Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-gamma interferon-treated mice. J Virol (1989) 1.60
Natural killer cells in mouse lung: surface phenotype, target preference, and response to local influenza virus infection. J Immunol (1983) 1.56
EPR characterization of molecular targets for NO in mammalian cells and organelles. FASEB J (1993) 1.54
Modulation of human polymorphonuclear leukocyte IgG Fc receptors and Fc receptor-mediated functions by IFN-gamma and glucocorticoids. J Immunol (1988) 1.49
Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype. J Immunol (1994) 1.43
Immune CD4+ T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epithelium. J Virol (1996) 1.42
Cellular mechanisms involved in protection and recovery from influenza virus infection in immunodeficient mice. J Virol (1996) 1.34
Interferon gamma gene expression in sensory neurons: evidence for autocrine gene regulation. J Exp Med (1997) 1.29
IFN-gamma is a prerequisite for optimal antigen processing of viral peptides in vivo. J Immunol (1997) 1.14
Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells. J Immunol (1998) 1.03
Interferon-gamma in vivo. Induction and loss of class II MHC antigens and immature myelomonocytic cells in rat organs. Eur J Immunol (1988) 1.00
DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus. Viral Immunol (1996) 0.99
In vivo depletion of interferon-gamma leads to susceptibility of A/J mice to mouse hepatitis virus 3 infection. Immunobiology (1992) 0.95
Nondetectable levels of interferon gamma is a critical host defense during the first day of herpes simplex virus infection. Microb Pathog (1987) 0.93
Intact antiinfluenza virus immune response in targeted kappa-deficient mice. Viral Immunol (1994) 0.88
Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice. Dev Immunol (1998) 0.82
Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones. J Exp Med (1981) 2.28
Postulates defining pathogenic autoantibodies and T cells. Autoimmunity (1991) 2.04
Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice. J Exp Med (1990) 1.91
Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med (1997) 1.53
Idiotype-anti-idiotype network. II. Activation of silent clones by treatment at birth with idiotypes is associated with the expansion of idiotype-specific helper T cells. J Exp Med (1982) 1.43
Idiotype vaccines: forgotten but not gone. Nat Med (1998) 1.42
Cellular mechanisms involved in protection and recovery from influenza virus infection in immunodeficient mice. J Virol (1996) 1.34
Shared idiotypes among monoclonal antibodies specific for different immunodominant sugars of lipopolysaccharide of different Gram-negative bacteria. Proc Natl Acad Sci U S A (1982) 1.24
Specificities and V genes encoding monoclonal autoantibodies from viable motheaten mice. J Exp Med (1988) 1.23
EMI, a novel cysteine-rich domain of EMILINs and other extracellular proteins, interacts with the gC1q domains and participates in multimerization. FEBS Lett (2000) 1.23
Immunologic response to influenza virus neuraminidase is influenced by prior experience with the associated viral hemagglutinin. II. Sequential infection of mice simulates human experience. J Immunol (1987) 1.13
Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies. Proc Natl Acad Sci U S A (1986) 1.10
Idiotypy of clonal responses to influenza virus hemagglutinin. J Exp Med (1981) 1.08
Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases. J Immunol (1999) 1.07
The EMILIN protein family. Matrix Biol (2000) 1.06
Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells. J Immunol (1998) 1.03
Regulatory arms of the immune network. Immunol Rev (1984) 1.02
Enhanced protection against influenza virus of mice immunized as newborns with a mixture of plasmids expressing hemagglutinin and nucleoprotein. Vaccine (1998) 1.01
Induction of skin fibrosis and autoantibodies by infusion of immunocompetent cells from tight skin mice into C57BL/6 Pa/Pa mice. J Autoimmun (1993) 1.01
CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes. Eur J Immunol (2001) 1.01
Characterization of variable-region genes and shared crossreactive idiotypes of antibodies specific for antigens of various influenza viruses. Viral Immunol (1987) 1.01
Shared idiotopes among monoclonal antibodies specific for A/PR/8/34 (H1N1) and X-31(H3N2) influenza viruses. Proc Natl Acad Sci U S A (1984) 1.00
Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation. J Exp Med (1999) 1.00
DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus. Viral Immunol (1996) 0.99
Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily. J Biol Chem (2001) 0.98
Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice. J Immunol (2001) 0.97
B-cell deficiency does not abrogate development of cutaneous hyperplasia in mice inheriting the defective fibrillin-1 gene. J Autoimmun (1997) 0.96
Functional and molecular studies of V genes expressed in autoantibodies. Immunol Rev (1986) 0.95
Characterization of monoclonal antibodies specific for sequential influenza A/PR/8/34 virus variants. J Immunol (1986) 0.95
Self-assembly and supramolecular organization of EMILIN. J Biol Chem (2000) 0.95
Isotype profiles of anti-influenza antibodies in mice bearing the xid defect. J Virol (1985) 0.95
In vitro idiotypic suppression of chronic lymphocytic leukemia lymphocytes secreting monoclonal immunoglobulin M anti-sheep erythrocyte antibody. J Clin Invest (1980) 0.95
Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus. J Exp Med (1993) 0.95
Epibody: the image of the network created by a single antibody. Immunol Rev (1986) 0.94
Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice. Autoimmunity (1998) 0.94
Escape from self-tolerance leads to neonatal insulin-dependent diabetes mellitus. Autoimmunity (1999) 0.94
Antigen presentation by murine and human cells to a murine T-cell hybridoma: demonstration of a restriction element associated with a major histocompatibility complex class II determinant(s) shared by both species. Proc Natl Acad Sci U S A (1984) 0.94
Immunochemical and molecular characterization of regulatory idiotopes expressed by monoclonal antibodies exhibiting or lacking beta 2-6 fructosan binding activity. J Exp Med (1985) 0.92
Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes. J Exp Med (1992) 0.92
Characterization of a (BALB/c x C57BL/6)F1 T cell hybridoma with double specificity: recognition of antigen in context of I-Ad and autoreactivity to I-Ab. Eur J Immunol (1984) 0.92
Shared idiotopes among antibodies encoded by heavy-chain variable region (VH) gene members of the J558 VH family as basis for cross-reactive regulation of clones with different antigen specificity. Proc Natl Acad Sci U S A (1985) 0.91
Possible role of anti-idiotypic antibodies in the induction of tumor immunity. J Clin Invest (1987) 0.91
Association of fibrillin 1 single-nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations. Arthritis Rheum (2001) 0.91
Repertoires of antigen receptors in Tdt congenitally deficient mice. Int Rev Immunol (1996) 0.91
Criteria to define anti-idiotypic antibodies carrying the internal image of an antigen. Vaccine (1988) 0.90
Engineering of doubly antigenized immunoglobulins expressing T and B viral epitopes. Immunotechnology (1996) 0.90
Self reactive repertoire of tight skin mouse: immunochemical and molecular characterization of anti-topoisomerase I autoantibodies. Autoimmunity (1991) 0.90
Anti-fibrillin-1 autoantibodies in systemic sclerosis are GM and KM allotype-restricted. Exp Clin Immunogenet (2001) 0.89
Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene. Int Immunol (1997) 0.88
Complexity of the immunoglobulin light chain V kappa 1 gene family in the New Zealand black mouse. Int Immunol (1991) 0.88
Intact antiinfluenza virus immune response in targeted kappa-deficient mice. Viral Immunol (1994) 0.88
Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen. Cancer Res (1999) 0.88
Protective immunity elicited by vaccination with DNA encoding for a B cell and a T cell epitope of the A/PR/8/34 influenza virus. Viral Immunol (1997) 0.88
Autoantibodies to fibrillin 1 in systemic sclerosis: ethnic differences in antigen recognition and lack of correlation with specific clinical features or HLA alleles. Arthritis Rheum (2000) 0.88
Contrasting efficacy of presentation by major histocompatibility complex class I and class II products when peptides are administered within a common protein carrier, self immunoglobulin. Eur J Immunol (1993) 0.87
Correlation between the concentration of serum anti-topoisomerase I autoantibodies and histological and biochemical alterations in the skin of tight skin mice. Cell Immunol (1996) 0.87
Immunogenicity of a contiguous T-B synthetic epitope of the A/PR/8/34 influenza virus. J Virol (1997) 0.86
Idiotype-antiidiotype regulation. IV. Expression of common regulatory idiotopes on fructosan-binding and non-fructosan-binding monoclonal immunoglobulin. J Exp Med (1983) 0.86
A targeted mutation in the IL-4Ralpha gene protects mice against autoimmune diabetes. Proc Natl Acad Sci U S A (2000) 0.85
Expression of the immunoglobulin heavy-chain variable gene repertoire. Curr Top Microbiol Immunol (1987) 0.85
Kinetics of generation and persistence on membrane class II molecules of a viral peptide expressed on foreign and self proteins. J Immunol (1996) 0.85
A sensitive method to detect defined peptide among those eluted from murine MHC class II molecules. J Immunol Methods (1993) 0.84
Anti-immunoglobulin antibodies. V. Age-dependent variation of clones stimulated by polysaccharide TI-2 antigens in 129 and MRL mice spontaneously producing anti-gamma-globulin antibodies. J Immunol (1984) 0.84
New method for titration of virus infectivity by immunostaining. Viral Immunol (1990) 0.84
Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes. J Exp Med (1995) 0.83
Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens. J Virol (2003) 0.83
Germline V genes encode viable motheaten mouse autoantibodies against thymocytes and red blood cells. J Immunol (1990) 0.83
Fine specificity of anti-fibrillin-1 autoantibodies in primary pulmonary hypertension syndrome. Scand J Immunol (2000) 0.83
Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice. Dev Immunol (1998) 0.82
Characterization of mutated protein encoded by partially duplicated fibrillin-1 gene in tight skin (TSK) mice. Mol Immunol (1999) 0.82
Idiotypes: structure and immunogenicity. FASEB J (1993) 0.82
Induction of antibody response by DNA immunization of newborn baboons against influenza virus. Viral Immunol (1999) 0.82
Functional properties of T cell clones with a double specificity for alloantigens and foreign antigens. J Exp Med (1984) 0.82
Functional characterization of monoclonal antibodies specific to growth hormone receptor. Mol Immunol (1996) 0.82
Idiotype-anti-idiotype network. III. Genetic control of activation of A48Id silent clones subsequent to manipulation of the immune network. Ann N Y Acad Sci (1983) 0.82
Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II--peptide chimera. Nat Biotechnol (2001) 0.82
Autoantibodies, LY-1, and immunoglobulin V gene expression in hybridomas obtained from young and from old New Zealand black mice. Arthritis Rheum (1990) 0.82
[Pinocytosis of bacterial toxins by macrophages and its immunological implications]. Arch Biol (Liege) (1971) 0.81
Idiotypy of anti-influenza virus immune responses. Concepts Immunopathol (1986) 0.81
Variable region gene selection of immunoglobulin G-expressing B cells with specificity for a defined epitope on type II collagen. Eur J Immunol (1993) 0.81
Engineering and characterization of a murine MHC class II-immunoglobulin chimera expressing an immunodominant CD4 T viral epitope. Protein Eng (1997) 0.81
Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins. Nat Biotechnol (1996) 0.80
Anti-immunoglobulin antibodies. VI. Age-dependent isotype and auto anti-immunoglobulin variation during secondary immune response in 129 mice. Mech Ageing Dev (1985) 0.80
A single amino acid mutation in CDR3 of the 3-14-9 L chain abolished expression of the IDA 10-defined idiotope and antigen binding. J Immunol (1992) 0.80
Induction of antibodies to the human immunodeficiency virus type 1 by immunization of baboons with immunoglobulin molecules carrying the principal neutralizing determinant of the envelope protein. Proc Natl Acad Sci U S A (1995) 0.80
Anti-immunoglobulin antibodies IV. Cross-reaction of anti-idiotypic antibodies specific for rabbit and murine anti-a1 allotype antibodies with Fc fragment of human immunoglobulins. Eur J Immunol (1984) 0.80
Promotion of animal growth with a monoclonal antibody specific to growth hormone receptor. Mol Cell Endocrinol (1996) 0.80
Inhibition of multicycle influenza virus replication by hybrid antibody-directed cytotoxic T lymphocyte lysis. J Immunol (1991) 0.80
Fate of endotoxin in macrophages: biological and ultrastructural aspects. J Infect Dis (1973) 0.79
Self-reactive repertoire of tight skin (TSK/+) mouse: immunochemical and molecular characterization of anti-cellular autoantibodies. Cell Immunol (1992) 0.79
Sideways killing: the cytolysis of Fc receptor-bearing cells through bridging to cytolytic T lymphocytes by antibodies specific for the T-cell receptor-T3 complex. Scand J Immunol (1989) 0.79
Distribution of theta antigens in ovum fusion derived AKR--CBA-H-T6T6 tetraparental mouse chimaeras. Tissue Antigens (1974) 0.79
Evidence for autoimmunity in the tight skin mouse model of systemic sclerosis. Arthritis Rheum (1991) 0.79
T-cell tolerance and autoimmune diabetes. Int Rev Immunol (2001) 0.78