IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression.

PubWeight™: 1.38‹?› | Rank: Top 10%

🔗 View Article (PMID 9661898)

Published in Cancer Res on July 01, 1998

Authors

X Xu1, X Y Fu, J Plate, A S Chong

Author Affiliations

1: Department of General Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA. xxu@rush.edu

Articles citing this

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis. J Exp Med (2001) 2.37

Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection. Springer Semin Immunopathol (2006) 2.09

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol (2000) 2.04

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9. Blood (2012) 1.67

Clearance of herpes simplex virus type 2 by CD8+ T cells requires gamma interferon and either perforin- or Fas-mediated cytolytic mechanisms. J Virol (2005) 1.45

STAT-1: a novel regulator of apoptosis. Int J Exp Pathol (2003) 1.43

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. Oncogene (2014) 1.30

Helicobacter pylori modulates lymphoepithelial cell interactions leading to epithelial cell damage through Fas/Fas ligand interactions. Infect Immun (2000) 1.23

STAT signaling in the pathogenesis and treatment of cancer. Mol Med (1999) 1.11

Intestinal inflammation and colorectal cancer: a double-edged sword? World J Gastroenterol (2011) 1.09

Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J Exp Med (1999) 1.07

Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. Br J Pharmacol (2006) 1.01

CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis. Immunol Rev (2013) 1.00

Expanding roles for CD4 T cells and their subpopulations in tumor immunity and therapy. Front Oncol (2013) 0.99

Genomic dissection of the cytokine-controlled STAT5 signaling network in liver. Physiol Genomics (2008) 0.99

Revisiting immunosurveillance and immunostimulation: Implications for cancer immunotherapy. J Transl Med (2005) 0.97

Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production. BMC Immunol (2008) 0.94

Cytokine production and dysregulation in HIV pathogenesis: lessons for development of therapeutics and vaccines. Cytokine Growth Factor Rev (2012) 0.93

Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing. Mol Cell Biol (2005) 0.91

Tumor proteomics by multivariate analysis on individual pathway data for characterization of vulvar cancer phenotypes. Mol Cell Proteomics (2012) 0.90

Tumor mouse model confirms MAGE-A3 cancer immunotherapeutic as an efficient inducer of long-lasting anti-tumoral responses. PLoS One (2014) 0.85

Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma). Ann Surg (2002) 0.83

Interleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondii. Infect Immun (2003) 0.81

Novel water-soluble polyurethane nanomicelles for cancer chemotherapy: physicochemical characterization and cellular activities. J Nanobiotechnology (2012) 0.81

Anti-inflammatory mechanisms of IFN-γ studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis. Front Neurosci (2015) 0.81

IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway. PLoS One (2011) 0.81

Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3. PLoS One (2015) 0.81

Solid tumor-targeted infiltrating cytotoxic T lymphocytes retained by a superantigen fusion protein. PLoS One (2011) 0.80

Fas counterattack in cholangiocarcinoma: a mechanism for immune evasion in human hilar cholangiocarcinomas. World J Gastroenterol (2001) 0.79

Recent advancement in understanding colitis-associated tumorigenesis. Inflamm Bowel Dis (2014) 0.79

Activation and modulation of antiviral and apoptotic genes in pigs infected with classical swine fever viruses of high, moderate or low virulence. Arch Virol (2009) 0.79

Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis. Virchows Arch (2007) 0.79

Cytotoxic proteins and therapeutic targets in severe cutaneous adverse reactions. Toxins (Basel) (2014) 0.76

Oxidative Stress Facilitates IFN-γ-Induced Mimic Extracellular Trap Cell Death in A549 Lung Epithelial Cancer Cells. PLoS One (2016) 0.76

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ (2017) 0.76

Association of FAS (TNFRSF6)-670 gene polymorphism with villous atrophy in coeliac disease. World J Gastroenterol (2004) 0.75

Polysaccharide-Rich Fraction of Noni Fruit (Morinda citrifolia L.) as Doxorubicin Co-Chemotherapy: Evaluation of Catalase, Macrophages, and TCD8+ Lymphocytes. Sci Pharm (2015) 0.75

Role of cytokines in promoting immune escape of FasL-expressing human colon cancer cells. World J Gastroenterol (2005) 0.75

Integrating Immunologic Signaling Networks: The JAK/STAT Pathway in Colitis and Colitis-Associated Cancer. Vaccines (Basel) (2016) 0.75

A WKYMVm-containing combination elicits potent anti-tumor activity in heterotopic cancer animal model. PLoS One (2012) 0.75

Articles by these authors

(truncated to the top 100)

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol (1992) 3.90

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science (1996) 3.70

Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev (1990) 3.65

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol (1997) 2.71

Factors influencing alternative splice site utilization in vivo. Mol Cell Biol (1987) 2.39

Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature (1997) 2.03

ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation. J Cell Biol (1999) 2.03

A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Hum Mol Genet (1999) 1.72

Infection with the intracellular bacterium, Listeria monocytogenes, overrides established tolerance in a mouse cardiac allograft model. Am J Transplant (2010) 1.68

STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science (1999) 1.38

Liver ischemia contributes to early islet failure following intraportal transplantation: benefits of liver ischemic-preconditioning. Am J Transplant (2006) 1.25

Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide. Intervirology (1999) 1.23

Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation. J Clin Invest (2000) 1.20

The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms. J Immunol (1997) 1.16

Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. J Biol Chem (1995) 1.15

Protective effect of ischemic preconditioning on liver preservation-reperfusion injury in rats. Transplantation (1998) 1.14

Use of G-protein fusions to monitor integral membrane protein-protein interactions in yeast. Nat Biotechnol (2000) 1.10

Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production. J Immunol (1998) 1.10

Leflunomide controls rejection in hamster to rat cardiac xenografts. Transplantation (1994) 1.09

Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation. Biochem Pharmacol (1996) 1.08

Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion. J Biol Chem (2001) 1.07

Novel mechanism of inhibition of cytomegalovirus by the experimental immunosuppressive agent leflunomide. Transplantation (1999) 1.06

c-myc is required for osteoclast differentiation. J Bone Miner Res (2002) 1.03

Regulation of B cell function by the immunosuppressive agent leflunomide. Transplantation (1996) 1.02

Transcriptional regulation of Fas gene expression by GA-binding protein and AP-1 in T cell antigen receptor.CD3 complex-stimulated T cells. J Biol Chem (1999) 1.00

Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression. J Immunol (2000) 0.98

Field efficacy of a new repellent, KBR 3023, against Aedes albopictus (SKUSE) and Culex quinquefasciatus (SAY) in a tropical environment. J Vector Ecol (1998) 0.97

IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice. Am J Transplant (2011) 0.96

Oligonucleotide-targeted degradation of U1 and U2 snRNAs reveals differential interactions of simian virus 40 pre-mRNAs with snRNPs. Nucleic Acids Res (1989) 0.96

Interferon-gamma has dual potentials in inhibiting or promoting cell proliferation. J Biol Chem (2000) 0.95

In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice. J Immunol (1997) 0.95

Inhibition of herpes simplex virus type 1 by the experimental immunosuppressive agent leflunomide. Transplantation (2001) 0.95

Interleukin-4 mediates cell growth inhibition through activation of Stat1. J Biol Chem (2000) 0.95

Extensive multi-organ metastasis following orthotopic onplantation of histologically-intact human bladder carcinoma tissue in nude mice. Int J Cancer (1991) 0.94

Patterns of insecticide resistance in onion thrips (Thysanoptera: Thripidae) in onion fields in New York. J Econ Entomol (2006) 0.93

In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action. Biochem Pharmacol (1999) 0.90

In vivo effects of leflunomide on normal pancreatic islet and syngeneic islet graft function. Transplantation (1997) 0.89

CD45-cross-linking stimulates IFN-gamma production in NK cells. J Immunol (1995) 0.89

Advances in control of onion thrips (Thysanoptera: Thripidae) in cabbage. J Econ Entomol (2008) 0.88

The portosystemic shunt protects liver against ischemic reperfusion injury. Transplantation (1999) 0.88

Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways. Blood (1995) 0.88

Expression of complement regulatory proteins in accommodated xenografts induced by anti-alpha-Gal IgG1 in a rat-to-mouse model. Am J Transplant (2007) 0.88

American society of transplantation symposium on B cells in transplantation: harnessing humoral immunity from rodent models to clinical practice. Am J Transplant (2007) 0.87

Nonimmune lymphocyte-macrophage interaction. II. Evidence that the interaction involves sulfated polysaccharide recognition. Cell Immunol (1985) 0.86

Multidrug resistance activity in human lymphocytes. Hum Immunol (1991) 0.85

The Src-protein tyrosine kinase Lck is required for IL-1-mediated costimulatory signaling in Th2 cells. J Immunol (2001) 0.85

Prolongation of rat islet allograft survival by the immunosuppressive agent leflunomide. Transplantation (1997) 0.84

Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig. Am J Transplant (2013) 0.84

Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase. Biochem J (1996) 0.84

Performance of ULV formulations (Pesguard 102/Vectobac 12AS) against three mosquito species. J Am Mosq Control Assoc (1997) 0.83

Regional and temporal variation in susceptibility to lambda-cyhalothrin in onion thrips, Thrips tabaci (Thysanoptera: Thripidae), in onion fields in New York. J Econ Entomol (2003) 0.82

Interferon alpha (IFN alpha) signaling in cells expressing the variant form of the type I IFN receptor. J Biol Chem (1994) 0.81

Genes for interleukin 7 are transcribed in leukemic cell subsets of individuals with chronic lymphocytic leukemia. J Exp Med (1993) 0.81

Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine. Transplantation (1994) 0.81

Nonimmune lymphocyte-macrophage interaction. I. Quantification by an automated colorimetric assay. Cell Immunol (1985) 0.80

Granulocyte colony-stimulating factor immunomodulation in the rat cardiac transplantation model. Transplantation (1996) 0.80

Cross-linking of CD45 on NK cells stimulates p56lck-mediated tyrosine phosphorylation and IFN-gamma production. J Immunol (1995) 0.79

Histological characterization and pharmacological control of chronic rejection in xenogeneic and allogeneic heart transplantation. Transplantation (1998) 0.79

Overwintering locations and hosts for onion thrips (Thysanoptera: Thripidae) in the onion cropping ecosystem in New York. J Econ Entomol (2007) 0.79

The structure of anti-Gal immunoglobulin genes in naïve and stimulated Gal knockout mice. Transplantation (2001) 0.79

FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation. Transplantation (1998) 0.78

Induction of species-specific host accommodation in the hamster-to-rat xenotransplantation model. J Immunol (1998) 0.78

Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action. J Pharmacol Exp Ther (1997) 0.78

Expression of milk-derived antihypertensive peptide in Escherichia coli. J Dairy Sci (2003) 0.78

Cellular therapies for type 1 diabetes. Horm Metab Res (2008) 0.77

Anti-CD4 therapy in combined heart-kidney, heart-liver, and heart-small bowel allotransplants in high-responder rats. Transplantation (1998) 0.77

Evidence that the cytoskeleton plays a key role in cell adhesion. Immunol Cell Biol (1987) 0.77

Dysfunction of Stat4 leads to accelerated incidence of chemical-induced thymic lymphomas in mice. Exp Mol Pathol (2001) 0.77

The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation. Cold Spring Harb Symp Quant Biol (1999) 0.77

Cell surface receptors for sulphated polysaccharides: a potential marker for macrophage subsets. Immunology (1986) 0.77

Helper signals in T-T cell collaboration. Ann N Y Acad Sci (1979) 0.77

Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection. Transplantation (2001) 0.77

In vitro and in vivo mechanisms of action of the antiproliferative and immunosuppressive agent, brequinar sodium. J Immunol (1998) 0.76

Making a B-line for transplantation tolerance. Am J Transplant (2011) 0.76

Down-regulation of beta1,4-galactosyltransferase gene expression by cell-cycle suppressor gene p16. Biochim Biophys Acta (1999) 0.76

Leflunomide immunosuppression in rat small intestinal transplantation. Transplant Proc (1994) 0.76

"Tip-toeing" to an assay for transplantation tolerance? Am J Transplant (2011) 0.75

Regulation of tumor necrosis factor secretion in leukocytes from alpha-1-antitrypsin deficient humans. Immunol Invest (1991) 0.75

Differential activation of the STAT pathway by angiotensin II via angiotensin type 1 and type 2 receptors in cultured human fetal mesangial cells. Exp Mol Pathol (2001) 0.75

[Clinical efficacy observation of atomization inhalation combined with oral administration of oseltamivir in 4 cases with H7N9 avian influenza]. Zhonghua Yi Xue Za Zhi (2017) 0.75

[Preparation of folate-targeted magnetic nanocomposites loaded with TFPI-2 plasmid and cisplatin and evaluation of its targeting and inhibitory effect on nasopharyngeal carcinoma HNE-1 cells in vitro]. Zhonghua Yi Xue Za Zhi (2016) 0.75

Modification of the clonogenic assay for the detection of lymphokine activated killer cell activity. J Immunol Methods (1990) 0.75

Glucose-galactose malabsorption--a report in a Chinese family. J Singapore Paediatr Soc (1989) 0.75

Leflunomide, a potential immunosuppressant for pancreatic islet transplantation. Transplant Proc (1997) 0.75

Cloning of oligopeptide transport carrier PepT1 and comparative analysis of PepT1 messenger ribonucleic acid expression in response to dietary nitrogen levels in yak () and indigenous cattle () on the Qinghai-Tibetan plateau. J Anim Sci (2016) 0.75

Splanchnic transplantation. Transplant Proc (1994) 0.75

Computer diagnosis of acid base disorders in a paediatric intensive care unit. J Singapore Paediatr Soc (1987) 0.75

Impact of straw mulch on populations of onion thrips (Thysanoptera: Thripidae) in onion. J Econ Entomol (2008) 0.75

Differential effect of leflunomide on concordant xenogeneic islet graft rejection and recurrence of autoimmune diabetes. Transplant Proc (1998) 0.75

[Chemical studies on the alkaloids isolated from the tuber of Yuanhu (Corydalis turtschaninovii Bees. f. yanhusuo Y. H. Chou et C. C. Hsu)]. Yao Xue Xue Bao (1986) 0.75

Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice. Transplant Proc (1997) 0.75

Gene gun-mediated gene transfer and expression in rat islets. Transplant Proc (1997) 0.75

Successful xenotransplantation of adult porcine islets in NOD and BALB/c mice with leflunomide and cyclosporine. Transplant Proc (1997) 0.75

[Chemical studies on the alkaloids from yuanhu (Corydalis turtschaninovii Bess. F. Yanhusuo Y. H. Chou et C.C. Hsu). VI. Separation and determination of 6 tertiary alkaloids in yuanhu by RP-HPLC]. Yao Xue Xue Bao (1986) 0.75

Allograft ultraviolet-B irradiation in rat small intestinal transplantation. Transplant Proc (1994) 0.75

Identification of a membrane-associated inhibitor(s) of epidermal growth factor-induced signal transducer and activator of transcription activation. J Biol Chem (1998) 0.75

Natural killer cell cytotoxicity and the multidrug resistance gene. Transplant Proc (1993) 0.75

Effect of anti-CD4 monoclonal antibody combined with human CTLA4Ig on the survival of hamster liver and heart xenografts in Lewis rats. Transplantation (1997) 0.75

Quantitation of the changes in splenic architecture during the rejection of cardiac allografts or xenografts. Transplantation (1997) 0.75