Published in Curr Opin Chem Biol on December 01, 1997
Substrate recognition by Escherichia coli MutY using substrate analogs. Nucleic Acids Res (1999) 1.09
TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature (2001) 11.84
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science (1998) 11.23
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature (2000) 4.62
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature (1993) 4.26
Structure of the NF-kappa B p50 homodimer bound to DNA. Nature (1995) 3.33
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr Biol (1996) 3.20
The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing. Cell (1995) 3.17
Molecular cloning and overexpression of the human FK506-binding protein FKBP. Nature (1990) 3.02
Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase. Biochemistry (1991) 2.77
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell (1998) 2.41
DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. J Mol Biol (1997) 2.37
Dynamic association of proteins with the pre-mRNA branch region. Genes Dev (1994) 2.36
Induced alpha helix in the VP16 activation domain upon binding to a human TAF. Science (1997) 2.35
The essential role of MEKK3 in TNF-induced NF-kappaB activation. Nat Immunol (2001) 2.32
Structural basis for the excision repair of alkylation-damaged DNA. Cell (1996) 2.23
Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J (2007) 2.16
DNA methyltransferases. Curr Opin Cell Biol (1994) 2.09
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science (1987) 1.91
A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr Biol (1997) 1.87
Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase. EMBO J (2001) 1.85
Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr Biol (1999) 1.84
Phylogeny of mRNA capping enzymes. Proc Natl Acad Sci U S A (1997) 1.84
Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 1.77
Reexpression of T-type Ca2+ channel gene and current in post-infarction remodeled rat left ventricle. Cardiovasc Res (2000) 1.72
Crystal structure of a thwarted mismatch glycosylase DNA repair complex. EMBO J (1999) 1.62
Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice. Proc Natl Acad Sci U S A (1999) 1.61
Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha. J Med Chem (1999) 1.52
The leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex. Chem Biol (1996) 1.44
Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. Nature (1997) 1.43
Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases. J Biol Chem (1998) 1.42
New technique for mouse oocyte injection via a modified holding pipette. Reprod Biomed Online (2010) 1.40
Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors. J Virol (2001) 1.40
The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2. Proc Natl Acad Sci U S A (1999) 1.38
The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution. Chem Biol (1997) 1.36
Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Curr Biol (1995) 1.32
Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution. EMBO J (1997) 1.31
Polyprenylphosphate-pentoses in mycobacteria are synthesized from 5-phosphoribose pyrophosphate. J Biol Chem (1996) 1.31
Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes. AIDS Res Hum Retroviruses (2000) 1.30
Epigenetic regulation of serotonin transporter expression and behavior in infant rhesus macaques. Genes Brain Behav (2010) 1.29
The D1 and D12 subunits are both essential for the transcription termination factor activity of vaccinia virus capping enzyme. J Virol (1995) 1.29
Human beta3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides. Bioorg Med Chem Lett (2000) 1.25
Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. Proc Natl Acad Sci U S A (1997) 1.25
High Ca(2+)-phosphate transfection efficiency enables single neuron gene analysis. Gene Ther (2004) 1.23
Chromosome instability contributes to loss of heterozygosity in mice lacking p53. Proc Natl Acad Sci U S A (2000) 1.23
Repair of DNA methylphosphotriesters through a metalloactivated cysteine nucleophile. Science (1993) 1.20
Molecular basis of bacterial resistance to organomercurial and inorganic mercuric salts. FASEB J (1988) 1.19
A second calcineurin binding site on the NFAT regulatory domain. Proc Natl Acad Sci U S A (2000) 1.16
Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct. Proc Natl Acad Sci U S A (1986) 1.16
Staphylococcus aureus cap5P encodes a UDP-N-acetylglucosamine 2-epimerase with functional redundancy. J Bacteriol (1999) 1.13
Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1. J Virol (2000) 1.12
The prevalence of plasmid-mediated AmpC beta-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae from five children's hospitals in China. Eur J Clin Microbiol Infect Dis (2008) 1.11
Neuroprotective effects of ginsenoside Rb1 on transient cerebral ischemia in rats. Brain Res (2007) 1.11
Characterization of emm types and superantigens of Streptococcus pyogenes isolates from children during two sampling periods. Epidemiol Infect (2009) 1.09
Potent and selective human beta(3)-adrenergic receptor antagonists. J Pharmacol Exp Ther (1999) 1.08
Transcriptional switching by the metalloregulatory MerR protein: initial characterization of DNA and mercury (II) binding activities. Biochemistry (1989) 1.08
A high-capacity column for affinity purification of sequence-specific DNA-binding proteins. Nucleic Acids Res (1992) 1.08
Trapping of a catalytic HIV reverse transcriptase*template:primer complex through a disulfide bond. Chem Biol (2000) 1.07
Solution structure of the core NFATC1/DNA complex. Cell (1998) 1.07
Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial. Neurology (2011) 1.07
Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists. Bioorg Med Chem Lett (2000) 1.06
A highly enantioselective chiral Lewis base-catalyzed asymmetric cyanation of ketones. J Am Chem Soc (2001) 1.05
Evidence for a non-alpha-helical DNA-binding motif in the Rel homology region. Proc Natl Acad Sci U S A (1994) 1.05
Downregulation of K(+) channel genes expression in type I diabetic cardiomyopathy. Biochem Biophys Res Commun (2001) 1.04
Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway. Curr Biol (1998) 1.04
Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2. J Virol (2000) 1.04
The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis. Oncogene (2010) 1.04
A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1. Proc Natl Acad Sci U S A (1996) 1.04
Human mesenchymal stem cells overexpressing pigment epithelium-derived factor inhibit hepatocellular carcinoma in nude mice. Oncogene (2010) 1.03
Inhibition of Tat-mediated transactivation of HIV-1 LTR transcription by polyamide nucleic acid targeted to TAR hairpin element. Biochemistry (2000) 1.03
Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein. J Am Chem Soc (2001) 1.03
Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme. J Virol (1997) 1.02
Gene expression. The amazing demethylase. Nature (1999) 1.02
Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1. Proc Natl Acad Sci U S A (1997) 1.02
Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer. Gene Ther (2009) 1.02
Synthesis and biochemical evaluation of RNA containing an intrahelical disulfide crosslink. Chem Biol (1995) 1.01
The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency. Proc Natl Acad Sci U S A (1998) 1.01
Biosynthetic origin of mycobacterial cell wall arabinosyl residues. J Bacteriol (1995) 1.00
Modifying the helical structure of DNA by design: recruitment of an architecture-specific protein to an enforced DNA bend. Chem Biol (1995) 1.00
Construction of an overproduction vector containing the novel srp (sterically repressed) promoter. Protein Sci (1994) 1.00
Overproduction of proteins using expression-cassette polymerase chain reaction. Methods Enzymol (1993) 0.97
Dynamics of ultraslow optical solitons in a cold three-state atomic system. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.97
Reaction of acid-activated mitomycin C with calf thymus DNA and model guanines: elucidation of the base-catalyzed degradation of N7-alkylguanine nucleosides. Biochemistry (1987) 0.96
The effects of N7-methylguanine on duplex DNA structure. Chem Biol (1994) 0.96
The Rel family of eukaryotic transcription factors. Curr Opin Struct Biol (1996) 0.95
Proteolysis regulates exposure of the IIICS-1 adhesive sequence in plasma fibronectin. Biochemistry (1996) 0.95
A nonnatural transcriptional coactivator. Proc Natl Acad Sci U S A (1997) 0.95
Asymmetric synthesis of alpha-amino acids via cinchona alkaloid-catalyzed kinetic resolution of urethane-protected alpha-amino acid N-carboxyanhydrides. J Am Chem Soc (2001) 0.95
In vivo loss of heterozygosity in T-cells of B6C3F1 Aprt(+/-) mice. Environ Mol Mutagen (2000) 0.94
The synthesis of an exhaustively stereodiversified library of cis-1,5 enediols by silyl-tethered ring-closing metathesis. Org Lett (2001) 0.94
Point mutagenesis of carboxyl-terminal amino acids of cholesteryl ester transfer protein. Opposite faces of an amphipathic helix important for cholesteryl ester transfer or for binding neutralizing antibody. J Biol Chem (1993) 0.93
Solution structure of the DNA methyl phosphotriester repair domain of Escherichia coli Ada. Biochemistry (1993) 0.93
Evidence for the absence of mutations at GJB3, GJB4 and LOR in progressive symmetrical erythrokeratodermia. Clin Exp Dermatol (2010) 0.92
Deconstruction of GCN4/GCRE into a monomeric peptide-DNA complex. Nat Struct Biol (1995) 0.92
Mutagenesis of the cysteines in the metalloregulatory protein MerR indicates that a metal-bridged dimer activates transcription. Biochemistry (1989) 0.91
Structural studies of the high mobility group globular domain and basic tail of HMG-D bound to disulfide cross-linked DNA. Biochemistry (2000) 0.91
Zinc binding by the methylation signaling domain of the Escherichia coli Ada protein. Biochemistry (1992) 0.91
Identification of a sequence within the C-terminal 26 amino acids of cholesteryl ester transfer protein responsible for binding a neutralizing monoclonal antibody and necessary for neutral lipid transfer activity. J Biol Chem (1992) 0.90
Pharmacological characterization of a recently described human beta 3-adrenergic receptor mutant. Endocrinology (1996) 0.89
Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides. Bioorg Med Chem Lett (1999) 0.89