Divergent cAMP signaling pathways regulate growth and pathogenesis in the rice blast fungus Magnaporthe grisea.

PubWeight™: 1.82‹?› | Rank: Top 3%

🔗 View Article (PMC 144070)

Published in Plant Cell on August 01, 1998

Authors

K Adachi1, J E Hamer

Author Affiliations

1: Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47906-1392, USA.

Articles citing this

Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev (2000) 5.49

Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans. Genetics (2001) 3.54

Under pressure: investigating the biology of plant infection by Magnaporthe oryzae. Nat Rev Microbiol (2009) 3.33

MAP kinase and protein kinase A-dependent mobilization of triacylglycerol and glycogen during appressorium turgor generation by Magnaporthe grisea. Plant Cell (2000) 2.35

Magnaporthe grisea pth11p is a novel plasma membrane protein that mediates appressorium differentiation in response to inductive substrate cues. Plant Cell (1999) 2.32

Independent signaling pathways regulate cellular turgor during hyperosmotic stress and appressorium-mediated plant infection by Magnaporthe grisea. Plant Cell (1999) 1.64

Peroxisomal metabolic function is required for appressorium-mediated plant infection by Colletotrichum lagenarium. Plant Cell (2001) 1.64

A mitogen-activated protein kinase cascade regulating infection-related morphogenesis in Magnaporthe grisea. Plant Cell (2005) 1.63

Regulation of conidiation and adenylyl cyclase levels by the Galpha protein GNA-3 in Neurospora crassa. Mol Cell Biol (2000) 1.51

The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus. Infect Immun (2004) 1.42

MoEnd3 regulates appressorium formation and virulence through mediating endocytosis in rice blast fungus Magnaporthe oryzae. PLoS Pathog (2017) 1.38

cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages. Mol Genet Genomics (2003) 1.38

Transcriptome analysis reveals new insight into appressorium formation and function in the rice blast fungus Magnaporthe oryzae. Genome Biol (2008) 1.37

Magnaporthe grisea cutinase2 mediates appressorium differentiation and host penetration and is required for full virulence. Plant Cell (2007) 1.35

Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae. PLoS Pathog (2012) 1.33

Multiple upstream signals converge on the adaptor protein Mst50 in Magnaporthe grisea. Plant Cell (2006) 1.21

Cell cycle-mediated regulation of plant infection by the rice blast fungus. Plant Cell (2010) 1.20

Gene discovery and gene function assignment in filamentous fungi. Proc Natl Acad Sci U S A (2001) 1.17

Stage-specific gene expression during urediniospore germination in Puccinia striiformis f. sp tritici. BMC Genomics (2008) 1.14

The pkaB gene encoding the secondary protein kinase A catalytic subunit has a synthetic lethal interaction with pkaA and plays overlapping and opposite roles in Aspergillus nidulans. Eukaryot Cell (2005) 1.09

The vacuole as central element of the lytic system and sink for lipid droplets in maturing appressoria of Magnaporthe grisea. Protoplasma (2001) 1.07

PDE1 encodes a P-type ATPase involved in appressorium-mediated plant infection by the rice blast fungus Magnaporthe grisea. Plant Cell (2001) 1.07

Environmental signals controlling sexual development of the corn Smut fungus Ustilago maydis through the transcriptional regulator Prf1. Plant Cell (1999) 1.05

Fungal model systems and the elucidation of pathogenicity determinants. Fungal Genet Biol (2014) 1.03

Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus. Appl Environ Microbiol (2008) 1.02

Two phosphodiesterase genes, PDEL and PDEH, regulate development and pathogenicity by modulating intracellular cyclic AMP levels in Magnaporthe oryzae. PLoS One (2011) 1.01

Shared and independent roles for a Galpha(i) protein and adenylyl cyclase in regulating development and stress responses in Neurospora crassa. Eukaryot Cell (2002) 1.01

Expression of Magnaporthe grisea avirulence gene ACE1 is connected to the initiation of appressorium-mediated penetration. Eukaryot Cell (2006) 0.98

PdeH, a high-affinity cAMP phosphodiesterase, is a key regulator of asexual and pathogenic differentiation in Magnaporthe oryzae. PLoS Pathog (2010) 0.98

New insights into the mechanism of light modulated signaling by heterotrimeric G-proteins: ENVOY acts on gna1 and gna3 and adjusts cAMP levels in Trichoderma reesei (Hypocrea jecorina). Fungal Genet Biol (2011) 0.97

The Cyclase-associated protein Cap1 is important for proper regulation of infection-related morphogenesis in Magnaporthe oryzae. PLoS Pathog (2012) 0.96

Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus. Mol Microbiol (2011) 0.92

MoFLP1, encoding a novel fungal fasciclin-like protein, is involved in conidiation and pathogenicity in Magnaporthe oryzae. J Zhejiang Univ Sci B (2009) 0.91

A Rho3 homolog is essential for appressorium development and pathogenicity of Magnaporthe grisea. Eukaryot Cell (2007) 0.89

Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms. J Biol Chem (2009) 0.88

Two novel transcriptional regulators are essential for infection-related morphogenesis and pathogenicity of the rice blast fungus Magnaporthe oryzae. PLoS Pathog (2011) 0.86

Identification of proteins that interact with two regulators of appressorium development, adenylate cyclase and cAMP-dependent protein kinase A, in the rice blast fungus Magnaporthe grisea. Mol Genet Genomics (2003) 0.85

A P-loop mutation in Gα subunits prevents transition to the active state: implications for G-protein signaling in fungal pathogenesis. PLoS Pathog (2012) 0.85

Cells in cells: morphogenetic and metabolic strategies conditioning rice infection by the blast fungus Magnaporthe oryzae. Protoplasma (2013) 0.84

Glycogen metabolic genes are involved in trehalose-6-phosphate synthase-mediated regulation of pathogenicity by the rice blast fungus Magnaporthe oryzae. PLoS Pathog (2013) 0.83

Ras GTPase activating protein CoIra1 is involved in infection-related morphogenesis by regulating cAMP and MAPK signaling pathways through CoRas2 in Colletotrichum orbiculare. PLoS One (2014) 0.83

Polyketides, Toxins and Pigments in Penicillium marneffei. Toxins (Basel) (2015) 0.82

Inactivation of the catalytic subunit of cAMP-dependent protein kinase A causes delayed appressorium formation and reduced pathogenicity of Colletotrichum gloeosporioides. ScientificWorldJournal (2012) 0.82

Regulation of appressorium development in pathogenic fungi. Curr Opin Plant Biol (2015) 0.82

Uniform categorization of biocommunication in bacteria, fungi and plants. World J Biol Chem (2010) 0.81

Temporal analysis of the magnaporthe oryzae proteome during conidial germination and cyclic AMP (cAMP)-mediated appressorium formation. Mol Cell Proteomics (2013) 0.80

MoSfl1 is important for virulence and heat tolerance in Magnaporthe oryzae. PLoS One (2011) 0.80

Magnaporthe oryzae MTP1 gene encodes a type III transmembrane protein involved in conidiation and conidial germination. J Zhejiang Univ Sci B (2008) 0.79

Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes. J Lipid Res (2014) 0.79

The late endosomal HOPS complex anchors active G-protein signaling essential for pathogenesis in magnaporthe oryzae. PLoS Pathog (2013) 0.79

GATA-Dependent Glutaminolysis Drives Appressorium Formation in Magnaporthe oryzae by Suppressing TOR Inhibition of cAMP/PKA Signaling. PLoS Pathog (2015) 0.79

Adenylate Cyclase AcyA Regulates Development, Aflatoxin Biosynthesis and Fungal Virulence in Aspergillus flavus. Front Cell Infect Microbiol (2016) 0.78

Structure-function analysis of Rgs1 in Magnaporthe oryzae: role of DEP domains in subcellular targeting. PLoS One (2012) 0.77

A weed reaches new heights down under Plant Cell (1999) 0.77

cAMP Signaling Regulates Synchronised Growth of Symbiotic Epichloë Fungi with the Host Grass Lolium perenne. Front Plant Sci (2016) 0.75

Protein kinase A regulatory subunit isoforms regulate growth and differentiation in Mucor circinelloides: essential role of PKAR4. Eukaryot Cell (2012) 0.75

More than just a surface thing. Rice infection by magnaporthe grisea Plant Cell (1999) 0.75

Using Network Extracted Ontologies to Identify Novel Genes with Roles in Appressorium Development in the Rice Blast Fungus Magnaporthe oryzae. Microorganisms (2017) 0.75

Phosphoproteome Analysis Links Protein Phosphorylation to Cellular Remodeling and Metabolic Adaptation during Magnaporthe oryzae Appressorium Development. J Proteome Res (2015) 0.75

The cAMP-PKA Signaling Pathway Regulates Pathogenicity, Hyphal Growth, Appressorial Formation, Conidiation, and Stress Tolerance in Colletotrichum higginsianum. Front Microbiol (2017) 0.75

Articles cited by this

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell (1987) 6.35

Efficient cloning of genes of Neurospora crassa. Proc Natl Acad Sci U S A (1986) 6.08

Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1982) 5.04

Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol (1987) 5.03

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes. Annu Rev Biochem (1990) 5.02

Identification and characterization of MPG1, a gene involved in pathogenicity from the rice blast fungus Magnaporthe grisea. Plant Cell (1993) 4.78

A mechanism for surface attachment in spores of a plant pathogenic fungus. Science (1988) 4.32

Transposon-facilitated DNA sequencing. Proc Natl Acad Sci U S A (1991) 4.29

Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev (1997) 4.28

MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev (1996) 3.81

Yeast pseudohyphal growth is regulated by GPA2, a G protein alpha homolog. EMBO J (1997) 3.41

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science (1995) 3.18

SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription. Mol Cell Biol (1995) 2.97

Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature (1994) 2.71

Signal transduction in yeast. Yeast (1994) 2.64

The adenylate cyclase gene MAC1 of Magnaporthe grisea controls appressorium formation and other aspects of growth and development. Plant Cell (1997) 2.59

SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits. Genes Dev (1988) 2.57

cAMP regulates morphogenesis in the fungal pathogen Ustilago maydis. Genes Dev (1994) 2.52

cAMP Regulates Infection Structure Formation in the Plant Pathogenic Fungus Magnaporthe grisea. Plant Cell (1993) 2.47

The cAMP-dependent protein kinase catalytic subunit is required for appressorium formation and pathogenesis by the rice blast pathogen Magnaporthe grisea. Plant Cell (1995) 2.46

G proteins in Ustilago maydis: transmission of multiple signals? EMBO J (1997) 2.42

Characterization of the Heterokaryotic and Vegetative Diploid Phases of MAGNAPORTHE GRISEA. Genetics (1986) 2.32

G protein alpha subunit genes control growth, development, and pathogenicity of Magnaporthe grisea. Mol Plant Microbe Interact (1997) 2.17

MPG1 Encodes a Fungal Hydrophobin Involved in Surface Interactions during Infection-Related Development of Magnaporthe grisea. Plant Cell (1996) 1.92

Distinct roles for two G protein alpha subunits in fungal virulence, morphology, and reproduction revealed by targeted gene disruption. Proc Natl Acad Sci U S A (1996) 1.84

Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis. EMBO J (1991) 1.72

Identification of fuz7, a Ustilago maydis MEK/MAPKK homolog required for a-locus-dependent and -independent steps in the fungal life cycle. Genes Dev (1994) 1.64

Leucine-rich repeats and carboxyl terminus are required for interaction of yeast adenylate cyclase with RAS proteins. Proc Natl Acad Sci U S A (1990) 1.63

Adenosine 3',5'-phosphate in fungi. Microbiol Rev (1981) 1.62

Yeast mating pheromone alpha factor inhibits adenylate cyclase. Proc Natl Acad Sci U S A (1980) 1.57

A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity. Biochem Biophys Res Commun (1974) 1.53

Cloning and analysis of CUT1, a cutinase gene from Magnaporthe grisea. Mol Gen Genet (1992) 1.52

Having a blast: exploring the pathogenicity of Magnaporthe grisea. Trends Microbiol (1995) 1.49

Loss of growth polarity and mislocalization of septa in a Neurospora mutant altered in the regulatory subunit of cAMP-dependent protein kinase. EMBO J (1996) 1.48

The Ustilago maydis regulatory subunit of a cAMP-dependent protein kinase is required for gall formation in maize. Plant Cell (1997) 1.39

Targeted disruption of a fungal G-protein beta subunit gene results in increased vegetative growth but reduced virulence. Mol Plant Microbe Interact (1997) 1.38

sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Genetics (1995) 1.37

SRA5 encodes the low-Km cyclic AMP phosphodiesterase of Saccharomyces cerevisiae. Mol Cell Biol (1988) 1.35

MPG1, a gene encoding a fungal hydrophobin of Magnaporthe grisea, is involved in surface recognition. Mol Plant Microbe Interact (1996) 1.28

Adenylyl cyclase deficient cr-1 (Crisp) mutant of Neurospora crassa: cyclic AMP-dependent nutritional deficiencies. Arch Microbiol (1979) 1.13

Yeast cAMP-dependent protein kinase regulatory subunit mutations display a variety of phenotypes. J Biol Chem (1990) 1.12

Characterization of Neurospora crassa mutant stratins deficient in adenylate cyclase activity. Arch Biochem Biophys (1977) 1.02

Low activity of the yeast cAMP-dependent protein kinase catalytic subunit Tpk3 is due to the poor expression of the TPK3 gene. Eur J Biochem (1993) 0.89

Inhibition of pathogenicity of the rice blast fungus by Saccharomyces cerevisiae alpha-factor. Science (1997) 0.88

Cloning and structural analysis of the gene for the regulatory subunit of cAMP-dependent protein kinase in Blastocladiella emersonii. J Biol Chem (1992) 0.85

A suppressor mutation which suppresses adenylyl cyclase mutations in Neurospora crassa. Exp Mycol (1995) 0.84

Lipolytic membrane release of two phosphatidylinositol-anchored cAMP receptor proteins in yeast alters their ligand-binding parameters. Arch Biochem Biophys (1994) 0.84

Analysis of the mechanism of activation of cAMP-dependent protein kinase through the study of mutants of the yeast regulatory subunit. Eur J Biochem (1996) 0.84

Articles by these authors

Transformation of Aspergillus nidulans by using a trpC plasmid. Proc Natl Acad Sci U S A (1984) 6.46

Identification and characterization of MPG1, a gene involved in pathogenicity from the rice blast fungus Magnaporthe grisea. Plant Cell (1993) 4.78

A mechanism for surface attachment in spores of a plant pathogenic fungus. Science (1988) 4.32

MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev (1996) 3.81

Identification and characterization of Aspergillus nidulans mutants defective in cytokinesis. Genetics (1994) 2.57

Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses. Proc Natl Acad Sci U S A (1998) 2.14

Developmental regulation of the Aspergillus nidulans trpC gene. Proc Natl Acad Sci U S A (1983) 1.88

Primary structure of the trpC gene from Aspergillus nidulans. Mol Gen Genet (1985) 1.87

Karyotypic Variation within Clonal Lineages of the Rice Blast Fungus, Magnaporthe grisea. Appl Environ Microbiol (1993) 1.75

The Colletotrichum lagenarium MAP kinase gene CMK1 regulates diverse aspects of fungal pathogenesis. Mol Plant Microbe Interact (2000) 1.69

An ATP-driven efflux pump is a novel pathogenicity factor in rice blast disease. EMBO J (1999) 1.68

The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity. EMBO J (1997) 1.57

Functional organization of the Aspergillus nidulans trpC promoter. Mol Cell Biol (1987) 1.43

Cytokinesis in Aspergillus nidulans is controlled by cell size, nuclear positioning and mitosis. J Cell Sci (1996) 1.36

Grasshopper, a long terminal repeat (LTR) retroelement in the phytopathogenic fungus Magnaporthe grisea. Mol Plant Microbe Interact (1993) 1.30

Recent advances in large-scale transposon mutagenesis. Curr Opin Chem Biol (2001) 1.23

sepB: an Aspergillus nidulans gene involved in chromosome segregation and the initiation of cytokinesis. EMBO J (1995) 1.20

Gene discovery and gene function assignment in filamentous fungi. Proc Natl Acad Sci U S A (2001) 1.17

hyp loci control cell pattern formation in the vegetative mycelium of Aspergillus nidulans. Genetics (1998) 1.13

Genetic organization of a repeated DNA sequence family in the rice blast fungus. Proc Natl Acad Sci U S A (1992) 1.10

Expression of an Escherichia coli beta-galactosidase fusion gene in Aspergillus nidulans. Gene (1985) 1.06

Characterization of a PR-10 pathogenesis-related gene family induced in rice during infection with Magnaporthe grisea. Mol Plant Microbe Interact (2001) 1.05

SEPH, a Cdc7p orthologue from Aspergillus nidulans, functions upstream of actin ring formation during cytokinesis. Mol Microbiol (2001) 1.03

Relationship of actin, microtubules, and crosswall synthesis during septation in Aspergillus nidulans. Cell Motil Cytoskeleton (1997) 1.02

Interaction between developmental and cell cycle regulators is required for morphogenesis in Aspergillus nidulans. EMBO J (1999) 1.01

Acropetal: a genetic locus required for conidiophore architecture and pathogenicity in the rice blast fungus. Fungal Genet Biol (1998) 0.98

Molecular probes for rice blast disease. Science (1991) 0.92

The Aspergillus nidulans septin encoding gene, aspB, is essential for growth. Fungal Genet Biol (1997) 0.92

Genetic differentiation in the rice blast fungus revealed by the distribution of the Fosbury retrotransposon. Fungal Genet Biol (1996) 0.89

Insertion of the LINE retrotransposon MGL causes a conidiophore pattern mutation in Magnaporthe grisea. Mol Plant Microbe Interact (2000) 0.85

Hypomorphic bimA(APC3) alleles cause errors in chromosome metabolism that activate the DNA damage checkpoint blocking cytokinesis in Aspergillus nidulans. Genetics (2000) 0.82

The ebb and flow of a fungal genome. Trends Microbiol (1993) 0.79

Rearrangements at a DNA-fingerprint locus in the rice blast fungus. Curr Genet (1996) 0.78

The timing of ribonucleic acid synthesis during the germination of heat-activated Dictyostelium discoideum spores. Can J Microbiol (1983) 0.77

The stage specific inhibition of Dictyostelium discoideum spore germination by the mutagen 4-nitroquinoline 1-oxide. Chem Biol Interact (1984) 0.77