Published in Proc Natl Acad Sci U S A on August 18, 1998
Candida albicans cell wall proteins. Microbiol Mol Biol Rev (2008) 2.11
A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics (2003) 1.76
Roles of Candida albicans Dfg5p and Dcw1p cell surface proteins in growth and hypha formation. Eukaryot Cell (2003) 1.65
Loss of function of KRE5 suppresses temperature sensitivity of mutants lacking mitochondrial anionic lipids. Mol Biol Cell (2004) 1.11
KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties. Eukaryot Cell (2004) 1.10
The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties. Eukaryot Cell (2002) 0.99
Molecular analysis of the Candida albicans homolog of Saccharomyces cerevisiae MNN9, required for glycosylation of cell wall mannoproteins. J Bacteriol (1999) 0.99
Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans. Infect Immun (2006) 0.94
Cell wall beta-(1,6)-glucan of Saccharomyces cerevisiae: structural characterization and in situ synthesis. J Biol Chem (2009) 0.91
Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis. Antimicrob Agents Chemother (2008) 0.88
Comparative pathogenicity of different Actinobacillus suis O/K serotypes. Can J Vet Res (2000) 0.87
Isolation of Candida glabrata homologs of the Saccharomyces cerevisiae KRE9 and KNH1 genes and their involvement in cell wall beta-1,6-glucan synthesis. J Bacteriol (1998) 0.87
Effect of beta-1,6-glucan inhibitors on the invasion process of Candida albicans: potential mechanism of their in vivo efficacy. Antimicrob Agents Chemother (2009) 0.82
The cellular roles of Ccr4-NOT in model and pathogenic fungi-implications for fungal virulence. Front Genet (2013) 0.82
Large-scale identification of putative exported proteins in Candida albicans by genetic selection. Eukaryot Cell (2002) 0.80
The complete genome sequence of Escherichia coli K-12. Science (1997) 84.27
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science (1995) 68.34
Life with 6000 genes. Science (1996) 41.51
Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii. Science (1996) 41.35
Isogenic strain construction and gene mapping in Candida albicans. Genetics (1993) 17.18
A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics (1987) 14.69
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast (1995) 13.20
In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol (1991) 8.90
The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med (1996) 6.49
Importance of Candida species other than C. albicans as pathogens in oncology patients. Clin Infect Dis (1995) 4.35
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrob Agents Chemother (1996) 4.24
Review: cell wall assembly in yeast. Yeast (1994) 4.19
Nosocomial candidiasis: emerging species, reservoirs, and modes of transmission. Clin Infect Dis (1996) 3.50
Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev (1995) 3.39
Architecture of the yeast cell wall. Beta(1-->6)-glucan interconnects mannoprotein, beta(1-->)3-glucan, and chitin. J Biol Chem (1997) 2.81
Epidemiology of candidiasis. J Hosp Infect (1995) 1.97
Attenuated virulence of chitin-deficient mutants of Candida albicans. Proc Natl Acad Sci U S A (1995) 1.73
K1 killer toxin, a pore-forming protein from yeast. Mol Microbiol (1991) 1.53
Glucomannoproteins in the cell wall of Saccharomyces cerevisiae contain a novel type of carbohydrate side chain. J Biol Chem (1994) 1.52
The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly. Mol Cell Biol (1993) 1.31
Isolation from Candida albicans of a functional homolog of the Saccharomyces cerevisiae KRE1 gene, which is involved in cell wall beta-glucan synthesis. J Bacteriol (1991) 1.24
Solubility of (1 leads to 3)-beta-D/(1 leads to 6)-beta-D-glucan in fungal walls: importance of presumed linkage between glucan and chitin. J Gen Microbiol (1981) 1.24
Analysis of wall glucans from yeast, hyphal and germ-tube forming cells of Candida albicans. J Gen Microbiol (1984) 1.22
Isolation of the Candida albicans homologs of Saccharomyces cerevisiae KRE6 and SKN1: expression and physiological function. J Bacteriol (1997) 1.17
Resistance of clinically important yeasts to antifungal agents. Int J Antimicrob Agents (1996) 1.14
The occurrence of glucosaminoglycan in the wall of Schizosaccharomyces pombe. J Gen Microbiol (1990) 1.10
The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Yeast (1996) 1.03
Epidemiological shifts in opportunistic and nosocomial Candida infections: mycological aspects. Int J Antimicrob Agents (1996) 0.97
beta-Glucosylated proteins in the cell wall of the black yeast Exophiala (Wangiella) dermatitidis. Microbiology (1997) 0.96
Life with 6000 genes. Science (1996) 41.51
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25
Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science (2001) 24.48
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (2001) 3.64
Effects of yeast killer factor on sensitive cells. Nat New Biol (1972) 3.43
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. Science (1997) 3.30
Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics (1997) 2.81
Yeast KRE genes provide evidence for a pathway of cell wall beta-glucan assembly. J Cell Biol (1990) 2.74
Managing oral anticoagulant therapy. Chest (2001) 2.25
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (1998) 2.17
Yeast killer toxin: purification and characterisation of the protein toxin from Saccharomyces cerevisiae. Eur J Biochem (1979) 2.12
Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. J Bacteriol (1999) 2.06
Sequence of the preprotoxin dsRNA gene of type I killer yeast: multiple processing events produce a two-component toxin. Cell (1984) 2.03
Physiology of killer factor in yeast. Adv Microb Physiol (1981) 1.99
The yeast KRE5 gene encodes a probable endoplasmic reticulum protein required for (1----6)-beta-D-glucan synthesis and normal cell growth. Mol Cell Biol (1990) 1.96
Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly. J Cell Biol (1994) 1.94
Cell wall receptor for yeast killer toxin: involvement of (1 leads to 6)-beta-D-glucan. J Bacteriol (1983) 1.90
Yeast Skn7p functions in a eukaryotic two-component regulatory pathway. EMBO J (1994) 1.88
SKN7, a yeast multicopy suppressor of a mutation affecting cell wall beta-glucan assembly, encodes a product with domains homologous to prokaryotic two-component regulators and to heat shock transcription factors. J Bacteriol (1993) 1.85
Glycosyl phosphatidylinositol-dependent cross-linking of alpha-agglutinin and beta 1,6-glucan in the Saccharomyces cerevisiae cell wall. J Cell Biol (1995) 1.85
Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and alpha-factor precursor processing. Cell (1987) 1.79
Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitro. Proc Natl Acad Sci U S A (1991) 1.74
Membrane-mediated killing of Saccharomyces cerevisiae by glycoproteins from Torulopsis glabrata. J Bacteriol (1975) 1.74
Fidelity of conjugation in Saccharomyces cerevisiae. Mol Gen Genet (1978) 1.71
Yeast Kex1p is a Golgi-associated membrane protein: deletions in a cytoplasmic targeting domain result in mislocalization to the vacuolar membrane. J Cell Biol (1992) 1.66
beta-1,6-Glucan synthesis in Saccharomyces cerevisiae. Mol Microbiol (2000) 1.66
Chromosomal mutants of Saccharomyces cerevisiae affecting the cell wall binding site for killer factor. Can J Microbiol (1978) 1.65
Isolation of CaSLN1 and CaNIK1, the genes for osmosensing histidine kinase homologues, from the pathogenic fungus Candida albicans. Microbiology (1998) 1.53
Yeast killer plasmid mutations affecting toxin secretion and activity and toxin immunity function. Mol Cell Biol (1982) 1.52
Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics (1992) 1.46
Yeast arginine permease: nucleotide sequence of the CAN1 gene. Curr Genet (1986) 1.46
Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast. Mol Biol Cell (2001) 1.44
SKN1 and KRE6 define a pair of functional homologs encoding putative membrane proteins involved in beta-glucan synthesis. Mol Cell Biol (1993) 1.43
Localization and targeting of the Saccharomyces cerevisiae Kre2p/Mnt1p alpha 1,2-mannosyltransferase to a medial-Golgi compartment. J Cell Biol (1995) 1.40
A mutational analysis of killer toxin resistance in Saccharomyces cerevisiae identifies new genes involved in cell wall (1-->6)-beta-glucan synthesis. Genetics (1993) 1.37
The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae. Biochim Biophys Acta (1999) 1.32
Binding of yeast killer toxin to a cell wall receptor on sensitive Saccharomyces cerevisiae. J Bacteriol (1979) 1.31
The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly. Mol Cell Biol (1993) 1.31
Mode of action of yeast toxins: energy requirement for Saccharomyces cerevisiae killer toxin. J Bacteriol (1977) 1.30
Yeast killer factor: ATP leakage and coordinate inhibition of macromolecular synthesis in sensitive cells. Biochim Biophys Acta (1973) 1.29
Yeast Skn7p activity is modulated by the Sln1p-Ypd1p osmosensor and contributes to regulation of the HOG pathway. Mol Gen Genet (1998) 1.28
Characterization of the yeast KEX1 gene product: a carboxypeptidase involved in processing secreted precursor proteins. Mol Cell Biol (1989) 1.25
Isolation from Candida albicans of a functional homolog of the Saccharomyces cerevisiae KRE1 gene, which is involved in cell wall beta-glucan synthesis. J Bacteriol (1991) 1.24
Regulation of cell wall beta-glucan assembly: PTC1 negatively affects PBS2 action in a pathway that includes modulation of EXG1 transcription. Mol Gen Genet (1995) 1.23
Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity. J Biol Chem (1995) 1.22
A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein. Yeast (1994) 1.20
Action of yeast killer factor: a resistant mutant with sensitive spheroplasts. J Bacteriol (1973) 1.20
Secretion of Saccharomyces cerevisiae killer toxin: processing of the glycosylated precursor. Mol Cell Biol (1983) 1.19
Yeast K1 killer toxin forms ion channels in sensitive yeast spheroplasts and in artificial liposomes. Proc Natl Acad Sci U S A (1990) 1.19
Biosynthesis of branched-chain amino acids in yeast: regulation of synthesis of the enzymes of isoleucine and valine biosynthesis. J Bacteriol (1969) 1.18
Histone H1 in Saccharomyces cerevisiae. Yeast (1997) 1.16
Killing of Torulopsis glabrata by Saccharomyces cerevisiae killer factor. Antimicrob Agents Chemother (1976) 1.15
Yeast killer toxin: site-directed mutations implicate the precursor protein as the immunity component. Cell (1986) 1.15
Toxicity of human adenovirus E4orf4 protein in Saccharomyces cerevisiae results from interactions with the Cdc55 regulatory B subunit of PP2A. Oncogene (2001) 1.10
Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells. J Cell Biol (1996) 1.09
The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains. J Biol Chem (1997) 1.08
Specific ion mediated chromatography of glycoproteins and neutral polysaccharides on substituted agarose gels. Anal Biochem (1975) 1.07
Saccharomyces cerevisiae killer expression mutant kex2 has altered secretory proteins and glycoproteins. Biochem Biophys Res Commun (1979) 1.07
The ALD6 gene of Saccharomyces cerevisiae encodes a cytosolic, Mg(2+)-activated acetaldehyde dehydrogenase. Yeast (1997) 1.06
CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1,6-glucan assembly. J Bacteriol (1996) 1.05
Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (1995) 1.05
Involvement of protein N-glycosyl chain glucosylation and processing in the biosynthesis of cell wall beta-1,6-glucan of Saccharomyces cerevisiae. Genetics (1998) 1.04
Biosynthesis of the branched-chain amino acids in yeast: a leucine-binding component and regulation of leucine uptake. J Bacteriol (1970) 1.04
Determination of the carboxyl termini of the alpha and beta subunits of yeast K1 killer toxin. Requirement of a carboxypeptidase B-like activity for maturation. J Biol Chem (1987) 1.03
The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Yeast (1996) 1.03
Identification of a Candida albicans ferrichrome transporter and its characterization by expression in Saccharomyces cerevisiae. J Biol Chem (2001) 1.03
Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem (1996) 1.02
The expression of cDNA clones of yeast M1 double-stranded RNA in yeast confers both killer and immunity phenotypes. EMBO J (1984) 1.01
Biosynthesis of the branched-chain amino acids in yeast: a trifluoroleucine-resistant mutant with altered regulation of leucine uptake. J Bacteriol (1970) 1.00
Comprehensive essential gene identification as a platform for novel anti-infective drug discovery. Curr Pharm Des (2002) 0.98
The yeast CWH41 gene encodes glucosidase I. Glycobiology (1997) 0.97
Depolarization of the actin cytoskeleton is a specific phenotype in Saccharomyces cerevisiae. J Cell Sci (1998) 0.95
Retention of cytoplasmic killer determinants in yeast cells after removal of mitochondrial DNA by ethidium bromide. Mol Gen Genet (1973) 0.95
Mutual antagonism among killer yeasts: competition between K1 and K2 killers and a novel cDNA-based K1-K2 killer strain of Saccharomyces cerevisiae. Can J Microbiol (1988) 0.95
Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: characterization of the 54 kb right terminal CDC15-FLO1-PHO11 region. Yeast (1997) 0.95
Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides. Glycobiology (1999) 0.94
Yeast plasma membrane ghosts. An analysis of proteins by two-dimensional gel electrophoresis. Biochim Biophys Acta (1979) 0.93
Identification of ASK10 as a multicopy activator of Skn7p-dependent transcription of a HIS3 reporter gene. Yeast (1996) 0.93
Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris. Biochem J (1997) 0.91
Yeast Kre1p is a cell surface O-glycoprotein. Mol Gen Genet (1995) 0.88
Isolation of Candida glabrata homologs of the Saccharomyces cerevisiae KRE9 and KNH1 genes and their involvement in cell wall beta-1,6-glucan synthesis. J Bacteriol (1998) 0.87
In vivo evidence for posttranslational translocation and signal cleavage of the killer preprotoxin of Saccharomyces cerevisiae. Mol Cell Biol (1986) 0.86
A DEX gene conferring production of extracellular amyloglucosidase on yeast. Gene (1985) 0.86
Topology of membrane insertion in vitro and plasma membrane assembly in vivo of the yeast arginine permease. Mol Microbiol (1988) 0.85
Yeast KEX1 protease cleaves a prohormone processing intermediate in mammalian cells. J Biol Chem (1990) 0.84