PubRank

J W Hanrahan

Author PubWeight™ 75.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Phosphorylation-regulated Cl- channel in CHO cells stably expressing the cystic fibrosis gene. Nature 1991 3.61
2 Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance. Cell 1991 3.56
3 Multi-ion pore behaviour in the CFTR chloride channel. Nature 1993 3.14
4 Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites. J Biol Chem 1993 2.85
5 CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli. Am J Physiol 1997 2.35
6 Permeability of wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels to polyatomic anions. J Gen Physiol 1997 2.26
7 Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene. J Biol Chem 1991 1.86
8 Failure of the cystic fibrosis transmembrane conductance regulator to conduct ATP. Science 1996 1.78
9 Disease-associated mutations in the fourth cytoplasmic loop of cystic fibrosis transmembrane conductance regulator compromise biosynthetic processing and chloride channel activity. J Biol Chem 1996 1.66
10 Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue. J Physiol 1996 1.61
11 Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels. J Gen Physiol 1997 1.51
12 Glutathione permeability of CFTR. Am J Physiol 1998 1.48
13 Multi-Ion mechanism for ion permeation and block in the cystic fibrosis transmembrane conductance regulator chloride channel. J Gen Physiol 1997 1.47
14 Phosphorylation by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A. J Biol Chem 1997 1.46
15 Adenosine triphosphate-dependent asymmetry of anion permeation in the cystic fibrosis transmembrane conductance regulator chloride channel. J Gen Physiol 1998 1.46
16 Low-conductance chloride channel activated by cAMP in the epithelial cell line T84. FEBS Lett 1990 1.45
17 Flickery block of single CFTR chloride channels by intracellular anions and osmolytes. Am J Physiol 1996 1.42
18 Phosphatase inhibitors activate normal and defective CFTR chloride channels. Proc Natl Acad Sci U S A 1994 1.34
19 The CFTR chloride channel: nucleotide interactions and temperature-dependent gating. J Membr Biol 1998 1.33
20 Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel. J Physiol 1998 1.33
21 CFTR channels expressed in CHO cells do not have detectable ATP conductance. J Membr Biol 1996 1.26
22 Disease-associated mutations in cytoplasmic loops 1 and 2 of cystic fibrosis transmembrane conductance regulator impede processing or opening of the channel. Biochemistry 1997 1.25
23 cAMP-dependent protein kinase-mediated phosphorylation of cystic fibrosis transmembrane conductance regulator residue Ser-753 and its role in channel activation. J Biol Chem 1995 1.22
24 Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity. J Biol Chem 1996 1.21
25 Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA. J Physiol 2003 1.19
26 Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl- channel expressed in mammalian cell lines. J Physiol 1998 1.19
27 Bicarbonate permeability of the outwardly rectifying anion channel. J Membr Biol 1989 1.14
28 Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore. Biophys J 2000 1.14
29 Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2C. J Biol Chem 1999 1.09
30 Regulation of the CFTR channel by phosphorylation. Pflugers Arch 2001 1.09
31 The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation. Biophys J 1992 1.08
32 Plasma membrane Na+/H+ exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways. J Biol Chem 1995 1.07
33 Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases. Am J Physiol 1998 1.06
34 Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum. Biochim Biophys Acta 1999 1.05
35 Asymmetric structure of the cystic fibrosis transmembrane conductance regulator chloride channel pore suggested by mutagenesis of the twelfth transmembrane region. Biochemistry 2001 1.00
36 Single anion-selective channels in basolateral membrane of a mammalian tight epithelium. Proc Natl Acad Sci U S A 1985 0.97
37 Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole. Am J Physiol Cell Physiol 2000 0.95
38 Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel. Br J Pharmacol 1999 0.95
39 Physiological approaches for studying mammalian urinary bladder epithelium. Methods Enzymol 1990 0.90
40 Regulation of an inwardly rectifying K channel in the T84 epithelial cell line by calcium, nucleotides and kinases. J Membr Biol 1994 0.87
41 cAMP- and Ca2+-independent activation of cystic fibrosis transmembrane conductance regulator channels by phenylimidazothiazole drugs. J Biol Chem 1996 0.85
42 Anion secretion by a model epithelium: more lessons from Calu-3. Acta Physiol (Oxf) 2011 0.85
43 Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel. Br J Pharmacol 1998 0.84
44 Transformed sweat gland and nasal epithelial cell lines from control and cystic fibrosis individuals. J Cell Sci 1990 0.84
45 Electrogenic, K+-dependent chloride transport in locust hindgut. Philos Trans R Soc Lond B Biol Sci 1982 0.84
46 The molecular basis of chloride transport in shark rectal gland. J Exp Biol 1994 0.82
47 Mutagenesis identifies amino acid residues in extracellular loops and within the barrel lumen that determine voltage gating of porin from Haemophilus influenzae type b. Biochemistry 2001 0.82
48 Basolateral K channel activated by carbachol in the epithelial cell line T84. J Membr Biol 1994 0.81
49 Charged residues in surface-located loops influence voltage gating of porin from Haemophilus influenzae type b. J Membr Biol 2000 0.79
50 Effects of EGTA on calcium signaling in airway epithelial cells. Am J Physiol 1994 0.79
51 Altered channel properties of porins from Haemophilus influenzae: isolates from cystic fibrosis patients. J Membr Biol 2002 0.79
52 Characterization of the inhibitory effect of boiled rice on intestinal chloride secretion in guinea pig crypt cells. Gastroenterology 1999 0.78
53 Apical and basolateral membrane ionic channels in rabbit urinary bladder epithelium. Pflugers Arch 1985 0.78
54 Intracellular calcium responses in CF/T43 cells: calcium pools and influx pathways. Am J Physiol 1997 0.77
55 On the activation of outwardly rectifying anion channels in excised patches. Am J Physiol 1991 0.77
56 Histamine stimulates a biphasic calcium response in the human tracheal epithelial cell line CF/T43. Am J Physiol 1993 0.76
57 Basolateral K channels in an insect epithelium. Channel density, conductance, and block by barium. J Gen Physiol 1986 0.76
58 Muscarinic-induced mucin secretion and intracellular signaling by hamster tracheal goblet cells. Am J Physiol 1997 0.75
59 Anion channels in the apical membrane of mammalian corneal epithelium primary cultures. Invest Ophthalmol Vis Sci 1991 0.75
60 Cellular mechanisms and control of KCl absorption in insect hindgut. J Exp Biol 1983 0.75