Published in Br J Clin Pharmacol on April 01, 1976
The effect of ageing on the hepatic clearance of propranolol. Br J Clin Pharmacol (1979) 1.45
Do saliva concentrations predict plasma unbound theophylline concentrations? A problem re-examined. Br J Clin Pharmacol (1984) 1.07
The effect of age on serum concentrations of albumin and alpha 1-acid glycoprotein. Br J Clin Pharmacol (1990) 1.03
Pharmacokinetics in the elderly. Environ Health Perspect (1994) 0.90
Kinetic study of serum penicillin concentrations after single doses of benzathine and benethamine penicillins in young and old people. Br J Vener Dis (1980) 0.76
Antibiotic therapy in aging patients. Bull N Y Acad Med (1987) 0.75
Drug prescribing for the elderly. West J Med (1981) 0.75
The effect of ageing on plasma albumin and plasma protein binding of diazepam, salicylic acid and digitoxin in healthy subjects and patients with renal impairment. Br J Clin Pharmacol (1992) 0.75
Rapid determination of salicylate in biological fluids. Biochem J (1954) 9.53
Predisposing factors in adverse reactions to drugs. Br Med J (1969) 5.80
Effect of age and sex on human drug metabolism. Br Med J (1971) 5.19
Studies on the epidemiology of adverse drug reactions. V. Clinical factors influencing susceptibility. Ann Intern Med (1966) 5.11
Changes in drug metabolism with increasing age: 2. phenytoin clearance and protein binding. Br J Clin Pharmacol (1975) 1.76
Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins. Br J Clin Pharmacol (1975) 1.46
Interindividual differences in the protein binding of sulfonamides: the effect of disease and drugs. Acta Pharmacol Toxicol (Copenh) (1971) 1.00
Developing and implementing clinical practice guidelines. Qual Health Care (1995) 6.52
The effects of enalapril on hypertension and quality of life. A large multicenter study in Belgium. Acta Cardiol (1989) 2.66
Treatment of primary osteosarcoma with intra-arterial and intravenous high-dose methotrexate. J Clin Oncol (1983) 2.35
Modelling theophylline response in individual patients with chronic bronchitis. Br J Clin Pharmacol (1981) 2.20
Disopyramide serum and pharmacologic effect kinetics applied to the assessment of bioavailability. Br J Clin Pharmacol (1978) 1.94
Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion. Ann Intern Med (1982) 1.85
Polyclonal and monoclonal antibody and PCR-amplified small-subunit rRNA identification of a microsporidian, Encephalitozoon hellem, isolated from an AIDS patient with disseminated infection. J Clin Microbiol (1994) 1.80
LATCH: a breastfeeding charting system and documentation tool. J Obstet Gynecol Neonatal Nurs (1994) 1.79
The modelling of drug response. Clin Sci (Lond) (1980) 1.79
Mechanical devices for arterial occlusion. Am J Roentgenol Radium Ther Nucl Med (1975) 1.72
Inflammation and arterial stiffness in systemic vasculitis: a model of vascular inflammation. Arthritis Rheum (2004) 1.71
Hepatic artery embolization in the treatment of hepatic neoplasms. Radiology (1981) 1.70
X-ray CT metal artifact reduction using wavelets: an application for imaging total hip prostheses. IEEE Trans Med Imaging (2000) 1.68
An epilepsy needs document. Seizure (1993) 1.64
The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients. AJR Am J Roentgenol (1991) 1.63
Quantitative analysis of the disopyramide concentration-effect relationship. Br J Clin Pharmacol (1980) 1.58
Cooperation of structural proteins during late events in the life cycle of polyomavirus. J Virol (1993) 1.58
The drug disc. Warning system for drug interactions. Lancet (1973) 1.56
An assessment of digoxin radio-immunoassay. Scott Med J (1973) 1.55
A new and improved "quick-hot Gram-chromotrope" technique that differentially stains microsporidian spores in clinical samples, including paraffin-embedded tissue sections. Arch Pathol Lab Med (1997) 1.53
Population pharmacokinetics. Theory and clinical application. Clin Pharmacokinet (1987) 1.53
Theophylline-salbutamol interaction: bronchodilator response to salbutamol at maximally effective plasma theophylline concentrations. Br J Clin Pharmacol (1981) 1.53
Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate. Cancer Res (1998) 1.51
Recombinant human erythropoietin for chronic renal failure anaemia in pre-dialysis patients. Cochrane Database Syst Rev (2001) 1.48
Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibition. J Biol Chem (1977) 1.47
Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery. Circulation (2001) 1.47
Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis. Mutat Res (1993) 1.44
Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage renal disease. Cochrane Database Syst Rev (2001) 1.44
Gliomatosis cerebri in a 10-year-old girl masquerading as diffuse encephalomyelitis and spinal cord tumour. Dev Med Child Neurol (2001) 1.43
Transcatheter occlusion of abdominal tumors. Radiology (1976) 1.41
A clinically significant interaction between ciprofloxacin and theophylline. Eur J Clin Pharmacol (1987) 1.41
Kinetic and dynamic comparison of piretanide and furosemide. Clin Pharmacol Ther (1978) 1.40
Primary hepatic lymphoma in a patient with chronic hepatitis C. J Gastroenterol Hepatol (1994) 1.39
Chemotherapy and embolization via the inferior epigastric artery for the treatment of primary and metastatic cancer. AJR Am J Roentgenol (1989) 1.39
Reproducibility and complications in gene searches: linkage on chromosome 6, heterogeneity, association, and maternal inheritance in juvenile myoclonic epilepsy. Am J Hum Genet (2000) 1.34
Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. The International Molecular Genetic Study of Autism Consortium. Am J Med Genet (1999) 1.31
Biodistribution of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in mice with ovarian OCa-1 tumor. Cancer Chemother Pharmacol (2000) 1.31
Comparison of scintigraphy, sonography, and computed tomography in the evaluation of hepatic neoplasms. AJR Am J Roentgenol (1979) 1.30
Cancer of the right lobe of the liver: a variety of operative procedures. Arch Surg (1972) 1.30
Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3. Nat Genet (1992) 1.29
Experimental design and efficient parameter estimation in population pharmacokinetics. J Pharmacokinet Biopharm (1990) 1.29
Acanthamoeba healyi n. sp. and the isoenzyme and immunoblot profiles of Acanthamoeba spp., groups 1 and 3. J Protozool (1992) 1.28
A comparison of cardiac biopsy grades and ejection fraction estimations in patients receiving Adriamycin. J Clin Oncol (1984) 1.28
Short-term in vitro culture and molecular analysis of the microsporidian, Enterocytozoon bieneusi. J Eukaryot Microbiol (1995) 1.27
In vitro culture and serologic and molecular identification of Septata intestinalis isolated from urine of a patient with AIDS. J Clin Microbiol (1995) 1.27
Angiographic classification of hepatic arterial collaterals. Radiology (1982) 1.26
Pathways of nodal metastasis from pelvic tumors: CT demonstration. Radiographics (1994) 1.24
Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors. Clin Cancer Res (1999) 1.24
Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence. Health Technol Assess (2010) 1.22
Accuracy of recall of surgical histories: a comparison of postal survey data and general practice records. Community Med (1985) 1.22
Percutaneous fine needle aspiration biopsy of pancreatic and other abdominal masses. Radiology (1977) 1.22
Culture, electron microscopy, and immunoblot studies on a microsporidian parasite isolated from the urine of a patient with AIDS. J Protozool (1992) 1.22
Angiographic changes due to needle biopsy of the liver. Radiology (1972) 1.21
Expressed genes, Alu repeats and polymorphisms in cosmids sequenced from chromosome 4p16.3. Nat Genet (1992) 1.21
Gram-chromotrope: a new technique that enhances detection of microsporidial spores in clinical samples. J Eukaryot Microbiol (1996) 1.21
Regression of ocular melanoma metastatic to the liver after hepatic arterial chemoembolization with cisplatin and polyvinyl sponge. JAMA (1988) 1.20
The accuracy of lymphangiography in carcinoma of the uterine cervix. Am J Roentgenol Radium Ther Nucl Med (1971) 1.19
The radiologic manifestations of alveolar soft-part sarcoma. AJR Am J Roentgenol (1989) 1.19
Inhibition of the spore polar filament extrusion of the microsporidium, Encephalitozoon hellem, isolated from an AIDS patient. J Eukaryot Microbiol (1994) 1.19
Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modifying genes influencing the seizure type. Ann Neurol (2001) 1.18
Clonal spread of methicillin-resistant Staphylococcus aureus in a large geographic area of the United States. J Hosp Infect (2003) 1.17
Myristylated polyomavirus VP2: role in the life cycle of the virus. J Virol (1990) 1.17
Uniform staining of Cyclospora oocysts in fecal smears by a modified safranin technique with microwave heating. J Clin Microbiol (1997) 1.17
Stenosis of the vena cava: preliminary assessment of treatment with expandable metallic stents. Radiology (1986) 1.17
Work in progress: transcatheter management of primary carcinoma of the liver. Radiology (1983) 1.15
Sonographic features of benign intraperitoneal lipomatous tumors in children--report of 4 cases. Pediatr Radiol (1990) 1.15
Small cell osteosarcoma. A clinicopathologic study of 27 cases. Cancer (1989) 1.15
OPT: a package of computer programs for parameter optimisation in clinical pharmacokinetics. Br J Clin Pharmacol (1982) 1.15
Percutaneous endovascular stents: an experimental evaluation. Radiology (1985) 1.15
Tumor irradiation enhances the tumor-specific distribution of poly(L-glutamic acid)-conjugated paclitaxel and its antitumor efficacy. Clin Cancer Res (2000) 1.14
Experimental design and efficient parameter estimation in preclinical pharmacokinetic studies. Pharm Res (1995) 1.13
The prediction of individual systolic time interval v heart rate regression equations. Br J Clin Pharmacol (1981) 1.13
Systolic time interval v heart rate regression equations using atropine: reproducibility studies. Br J Clin Pharmacol (1981) 1.12
Comparative pharmacokinetics and pharmacodynamics of cardiac glycosides. Br J Clin Pharmacol (1980) 1.11
Phenytoin concentrations in mixed, parotid and submandibular saliva and serum measured by radioimmunoassay. Br J Clin Pharmacol (1977) 1.11
Modeling of drug response in individual subjects. J Pharmacokinet Biopharm (1980) 1.11
Effect of misspecification of the absorption process on subsequent parameter estimation in population analysis. J Pharmacokinet Biopharm (1993) 1.09
Isolation of Nosema algerae from the cornea of an immunocompetent patient. J Eukaryot Microbiol (1999) 1.09
Pediatric osteosarcoma: therapeutic strategies, results, and prognostic factors derived from a 10-year experience. J Clin Oncol (1990) 1.09
Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal. Am J Med (1989) 1.09
Arterial occlusion: management of giant cell tumor and aneurysmal bone cyst. AJR Am J Roentgenol (1981) 1.09
Development and initial experimental evaluation of a prosthetic aortic valve for transcatheter placement. Work in progress. Radiology (1992) 1.09
Recombinant human erythropoietin for chronic renal failure anaemia in pre-dialysis patients. Cochrane Database Syst Rev (2005) 1.09
Absence of hepatic segment of the inferior vena cava with azygous continuation. J Comput Assist Tomogr (1980) 1.08
Pathologic fracture in osteosarcoma. Impact of chemotherapy on primary tumor and survival. Cancer (1987) 1.07
Who needs molar units for drugs? Lancet (1987) 1.07
Bayesian parameter estimation and population pharmacokinetics. Clin Pharmacokinet (1992) 1.07
The palliative role of hepatic arterial infusion and arterial occlusion in colorectal carcinoma metastatic to the liver. Lancet (1981) 1.06
Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225. J Nucl Med (2001) 1.06
Acanthamoeba meningoencephalitis in a patient with acquired immunodeficiency syndrome. Arch Pathol Lab Med (1992) 1.06
Pyruvate dehydrogenase activity and malonyl CoA levels in normal and ischemic swine myocardium: effects of dichloroacetate. J Mol Cell Cardiol (1996) 1.05
Arterial occlusion of pelvic bone tumors. Cancer (1979) 1.05
Islet cell tumors metastatic to the liver: effective palliation by sequential hepatic artery embolization. Ann Intern Med (1988) 1.05
Systematic review of the clinical effectiveness and cost-effectiveness of tension-free vaginal tape for treatment of urinary stress incontinence. Health Technol Assess (2003) 1.04
Ultrastructure, immunofluorescence, western blot, and PCR analysis of eight isolates of Encephalitozoon (Septata) intestinalis established in culture from sputum and urine samples and duodenal aspirates of five patients with AIDS. J Clin Microbiol (1998) 1.04
Estimation of gentamicin clearance and volume of distribution in neonates and young children. Br J Clin Pharmacol (1984) 1.04
The clinical and radiologic manifestations of hemangiopericytoma. AJR Am J Roentgenol (1989) 1.02
Merkel cell carcinoma of the skin: imaging and clinical features in 93 cases. Br J Radiol (1996) 1.02
Effect of acute alcohol intoxication on the metabolism and plasma kinetics of chlordiazepoxide. Br J Clin Pharmacol (1979) 1.01
Transcatheter arterial embolization in the management of bleeding in the cancer patient. Radiology (1975) 1.01