J G van de Winkel

Author PubWeight™ 114.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 1996 2.96
2 A single amino acid in the second Ig-like domain of the human Fc gamma receptor II is critical for human IgG2 binding. J Immunol 1991 2.48
3 The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J 1997 2.34
4 IgA and the IgA Fc receptor. Trends Immunol 2001 2.05
5 On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2. J Clin Invest 1992 2.04
6 Molecular basis for a polymorphism of human Fc gamma receptor II (CD32). J Exp Med 1990 1.79
7 Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1. J Virol 2001 1.64
8 IgG receptor polymorphisms: risk factors for disease. Immunogenetics 1998 1.59
9 Cocapping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fc gamma receptor III on human neutrophils. Possible role of lectin-like interactions. J Immunol 1993 1.55
10 Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16). J Immunol 1998 1.49
11 Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies. Immunol Today 1997 1.48
12 Inflammation in autoimmunity: receptors for IgG revisited. Trends Immunol 2001 1.41
13 Fc gamma receptor IIa (CD32) polymorphism in fulminant meningococcal septic shock in children. J Infect Dis 1994 1.37
14 Phagocytosis of Staphylococcus aureus and Haemophilus influenzae type B opsonized with polyclonal human IgG1 and IgG2 antibodies. Functional hFc gamma RIIa polymorphism to IgG2. J Immunol 1993 1.29
15 The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. J Biol Chem 1998 1.25
16 Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections. J Infect Dis 1994 1.25
17 Human immunoglobulin G (IgG) Fc receptor IIA (CD32) polymorphism and IgG2-mediated bacterial phagocytosis by neutrophils. Infect Immun 1995 1.24
18 Functional association between the human myeloid immunoglobulin A Fc receptor (CD89) and FcR gamma chain. Molecular basis for CD89/FcR gamma chain association. J Biol Chem 1995 1.23
19 Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice. J Clin Invest 1996 1.23
20 FcalphaRI-positive liver Kupffer cells: reappraisal of the function of immunoglobulin A in immunity. Nat Med 2000 1.19
21 Immunoglobulin A-mediated protection against Bordetella pertussis infection. Infect Immun 2001 1.19
22 Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation. Blood 2001 1.18
23 Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia. Blood 2001 1.17
24 FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. Blood 1996 1.15
25 A novel PCR-based method for direct Fc gamma receptor IIIa (CD16) allotyping. J Immunol Methods 2000 1.15
26 Structure and function of human IgA Fc receptors (Fc alpha R). Crit Rev Immunol 1996 1.15
27 Role of Fc receptor gamma chain in inflammation and cartilage damage during experimental antigen-induced arthritis. Arthritis Rheum 2000 1.13
28 Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy. Blood 1993 1.13
29 The FcgammaRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain. Blood 1999 1.11
30 Expression of IgG Fc receptor antigens in placenta and on endothelial cells in humans. An immunohistochemical study. Am J Pathol 1991 1.10
31 Fc receptor-mediated immunity against Bordetella pertussis. J Immunol 2001 1.07
32 Clinical relevance of Fc gamma receptor polymorphisms. Ann N Y Acad Sci 1997 1.07
33 Human C-reactive protein does not bind to FcgammaRIIa on phagocytic cells. J Clin Invest 2001 1.07
34 Heparin-induced thrombocytopenia: new insights into the impact of the FcgammaRIIa-R-H131 polymorphism. Blood 1998 1.04
35 Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products. J Biol Chem 1992 1.04
36 Human immunoglobulin A receptor (FcalphaRI, CD89) function in transgenic mice requires both FcR gamma chain and CR3 (CD11b/CD18). Blood 1999 1.03
37 Crucial role of FcgammaRIIa (CD32) in assessment of functional anti-Streptococcus pneumoniae antibody activity in human sera. J Infect Dis 1999 1.03
38 Fcgamma receptor polymorphisms in Wegener's granulomatosis: risk factors for disease relapse. Arthritis Rheum 1999 1.02
39 Fc receptor and complement receptor-mediated phagocytosis in host defence. Curr Opin Infect Dis 1998 1.02
40 The human low affinity immunoglobulin G Fc receptor IIC gene is a result of an unequal crossover event. J Biol Chem 1993 1.01
41 Interaction between hybrid mouse monoclonal antibodies and the human high-affinity IgG FcR, huFc gamma RI, on U937. Involvement of only one of the mIgG heavy chains in receptor binding. J Immunol 1989 1.01
42 Human Fc gamma receptor II: a standby receptor activated by proteolysis? Immunol Today 1990 1.01
43 Fcgamma receptor polymorphisms in systemic lupus erythematosus: association with disease and in vivo clearance of immune complexes. Arthritis Rheum 2000 1.00
44 Human low-affinity IgG receptor Fc gamma RIIa (CD32) introduced into mouse fibroblasts mediates phagocytosis of sensitized erythrocytes. Blood 1992 0.99
45 Association of human Fc gamma RIIa (CD32) polymorphism with susceptibility to and severity of meningococcal disease. Clin Infect Dis 1998 0.98
46 Triggering Fc alpha-receptor I (CD89) recruits neutrophils as effector cells for CD20-directed antibody therapy. J Immunol 2000 0.98
47 CD16 on human gamma delta T lymphocytes: expression, function, and specificity for mouse IgG isotypes. Cell Immunol 1992 0.98
48 Effective phagocytosis and killing of Candida albicans via targeting FcgammaRI (CD64) or FcalphaRI (CD89) on neutrophils. J Infect Dis 1999 0.98
49 HLA class II as potential target antigen on malignant B cells for therapy with bispecific antibodies in combination with granulocyte colony-stimulating factor. Blood 1996 0.97
50 Granulocyte colony-stimulating factor induces hFc gamma RI (CD64 antigen)-positive neutrophils via an effect on myeloid precursor cells. Blood 1993 0.97
51 Fcgamma receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms. Arthritis Rheum 1998 0.97
52 CR3 (alphaM beta2; CD11b/CD18) restores IgG-dependent phagocytosis in transfectants expressing a phagocytosis-defective Fc gammaRIIA (CD32) tail-minus mutant. J Immunol 1996 0.96
53 Pneumococcal capsular polysaccharide-specific IgA triggers efficient neutrophil effector functions via FcalphaRI (CD89). J Infect Dis 2000 0.95
54 The human Fc receptor for IgA (Fc alpha RI, CD89) on transgenic peritoneal macrophages triggers phagocytosis and tumor cell lysis. Immunol Lett 1999 0.95
55 Multiplex screening for functionally rearranged immunoglobulin variable regions reveals expression of hybridoma-specific aberrant V-genes. J Immunol Methods 2001 0.95
56 Meningococcal disease and polymorphism of FcgammaRIIa (CD32) in late complement component-deficient individuals. Clin Exp Immunol 1998 0.94
57 Immunoglobulin-binding sites of human FcalphaRI (CD89) and bovine Fcgamma2R are located in their membrane-distal extracellular domains. J Exp Med 1999 0.94
58 Evaluating antibodies for their capacity to induce cell-mediated lysis of malignant B cells. Cancer Res 1998 0.93
59 Human IgG Fc receptors. Int Rev Immunol 1997 0.93
60 FcalphaRI (CD89) as a novel trigger molecule for bispecific antibody therapy. Blood 1997 0.93
61 The cytoplasmic domain of FcgammaRIIA (CD32) participates in phagolysosome formation. Blood 2001 0.91
62 Mechanisms of G-CSF- or GM-CSF-stimulated tumor cell killing by Fc receptor-directed bispecific antibodies. J Immunol Methods 2001 0.91
63 Fc receptor binding of anti-CD3 monoclonal antibodies is not essential for immunosuppression, but triggers cytokine-related side effects. Eur J Immunol 1995 0.90
64 IgG receptor IIa alleles determine susceptibility and severity of Guillain-Barré syndrome. Neurology 2000 0.90
65 Preclinical studies with Fc(gamma)R bispecific antibodies and granulocyte colony-stimulating factor-primed neutrophils as effector cells against HER-2/neu overexpressing breast cancer. Cancer Res 1997 0.90
66 The role of FcR in immunity: lessons from gene targeting in mice. Res Immunol 1997 0.90
67 Antitumor immune effector mechanisms recruited by phage display-derived fully human IgG1 and IgA1 monoclonal antibodies. Cancer Res 1999 0.89
68 Structure of the gene for the human myeloid IgA Fc receptor (CD89). J Immunol 1995 0.88
69 Granulocyte-macrophage colony-stimulating factor induces sequential activation and deactivation of binding via a low-affinity IgG Fc receptor, hFc gamma RII, on human eosinophils. Blood 1993 0.88
70 Interaction of a human Fc gamma RIIb1 (CD32) isoform with murine and human IgG subclasses. Int Immunol 1993 0.88
71 Human antibodies as next generation therapeutics. Curr Opin Chem Biol 2001 0.88
72 Heterogeneity of human IgG Fc receptors. Immunomethods 1994 0.87
73 Characterization of IgG FcR-mediated proliferation of human T cells induced by mouse and human anti-CD3 monoclonal antibodies. Identification of a functional polymorphism to human IgG2 anti-CD3. J Immunol 1992 0.87
74 Diagnosis of renal allograft rejection by macrophage immunostaining with a CD14 monoclonal antibody, WT14. Lancet 1989 0.85
75 Polymorphism of the human Fc gamma receptor II (CD32): molecular basis and functional aspects. Immunobiology 1992 0.85
76 Relevance of immunoglobulin G Fc receptor polymorphism to recurrence of adult periodontitis in Japanese patients. Infect Immun 1997 0.84
77 Anti-GPIIb/IIIa (CD41) monoclonal antibody-induced platelet activation requires Fc receptor-dependent cell-cell interaction. Br J Haematol 1991 0.84
78 Size-dependent effect of IgA on the IgA Fc receptor (CD89). Eur J Immunol 1997 0.84
79 Evidence for an intracellular niche for Bordetella pertussis in broncho-alveolar lavage cells of mice. FEMS Immunol Med Microbiol 1999 0.84
80 The alternatively spliced CD64 transcript FcgammaRIb2 does not specify a surface-expressed isoform. Eur J Immunol 1999 0.83
81 Alternatively spliced forms of the human myeloid Fc alpha receptor (CD89) in neutrophils. Immunogenetics 1996 0.83
82 Relevance of IgG receptor IIIb (CD16) polymorphism to handling of Porphyromonas gingivalis: implications for the pathogenesis of adult periodontitis. J Periodontal Res 2000 0.83
83 Increased frequency of FcgammaRIIIb-NA1 allele in periodontitis-resistant subjects in an elderly Japanese population. J Dent Res 2001 0.82
84 Interaction of human monocyte Fc gamma receptors with rat IgG2b. A new indicator for the Fc gamma RIIa (R-H131) polymorphism. J Immunol 1995 0.82
85 Enhancement of polymorphonuclear cell-mediated tumor cell killing on simultaneous engagement of fcgammaRI (CD64) and fcalphaRI (CD89). Cancer Res 2001 0.82
86 A novel role for IgG-Fc. Transductional potentiation for human high affinity Fc gamma receptor (Fc gamma RI) signaling. J Biol Chem 1995 0.81
87 Cytotoxicity of anti-CD64-ricin a chain immunotoxin against human acute myeloid leukemia cells in vitro and in SCID mice. J Hematother Stem Cell Res 2001 0.81
88 Analysis of factors contributing to the formation of mononuclear cell aggregates ("escapees") in flow cytometric immunophenotyping. Cytometry 1997 0.81
89 The Fcgamma receptor genotype as a risk factor for generalized early-onset periodontitis in Japanese patients. J Periodontol 2000 0.80
90 Presence of CD16 on endothelial cells in heart transplant rejection: an immunohistochemical study. Scand J Immunol 1992 0.80
91 Phagocytosis and intracellular killing of serum-opsonized Staphylococcus aureus by mouse fibroblasts expressing human Fcgamma receptor type IIa (CD32). Front Biosci 1996 0.80
92 Effect of isotype on internalization and cytotoxicity of CD19-ricin A immunotoxins. Cancer Res 1994 0.80
93 Neutrophil Fc gamma RI as target for immunotherapy of invasive candidiasis. J Immunol 2001 0.80
94 Identification and structural characterization of Fc gamma-receptors on pulmonary alveolar macrophages. Am J Physiol 1991 0.80
95 Clinical evaluation of the bispecific antibody MDX-H210 (anti-Fc gamma RI x anti-HER-2/neu) in combination with granulocyte-colony-stimulating factor (filgrastim) for treatment of advanced breast cancer. Cancer Immunol Immunother 1998 0.79
96 Immunoadjuvant activity of a liposomal IL-6 formulation. Vaccine 1993 0.79
97 Reduced binding of immunoglobulin A (IgA) from patients with primary IgA nephropathy to the myeloid IgA Fc-receptor, CD89. Nephrol Dial Transplant 1998 0.79
98 On the interaction between agalactosyl IgG and Fc gamma receptors. Eur J Immunol 1996 0.79
99 The Fc gamma receptor genotype as a severity factor for chronic periodontitis in Japanese patients. J Periodontol 2001 0.78
100 Selective enhancement of Leu-CAM expression by interleukin 6 during differentiation of human promonocytic U937 cells. Scand J Immunol 1991 0.78
101 Isotype-specific cross-linking of select human Fc gamma R isoforms triggers release of IL-6. Clin Exp Immunol 1993 0.77
102 Generation of HER-2/neu-specific cytotoxic neutrophils in vivo: efficient arming of neutrophils by combined administration of granulocyte colony-stimulating factor and Fcgamma receptor I bispecific antibodies. J Immunol 1997 0.77
103 Synergism of interleukin 6 and 1 alpha,25-dihydroxyvitamin D3 in induction of myeloid differentiation of human leukemic cell lines. J Leukoc Biol 1992 0.77
104 Effective in vitro clearance of Porphyromonas gingivalis by Fc alpha receptor I (CD89) on gingival crevicular neutrophils. Infect Immun 2001 0.77
105 A single injection of polyethylene-glycol granulocyte colony-stimulating factor strongly prolongs survival of mice with systemic candidiasis. Cytokine 2000 0.77
106 Antigen topography is critical for interaction of IgG2 anti-red-cell antibodies with Fc gamma receptors. Br J Haematol 1996 0.77
107 Characterization of the human myeloid IgA Fc receptor I (CD89) gene in a cosmid clone. Immunogenetics 1999 0.77
108 [Immunology in clinical practice. X. IgG receptors: structure, function and immunotherapy]. Ned Tijdschr Geneeskd 1998 0.77
109 Assignment of three human high-affinity Fc gamma receptor I genes to chromosome 1, band q21.1. Immunogenetics 1993 0.75
110 [Immunology in clinical practice. XI. IgG receptors: the role of polymorphism in autoimmune and infectious diseases]. Ned Tijdschr Geneeskd 1998 0.75
111 Clinical perspectives of bispecific antibodies in cancer. Cancer Immunol Immunother 1998 0.75
112 Immunohistologic staining of renal transplant biopsies with monoclonal antibody WT14: a new parameter for the diagnosis of rejection. Transplant Proc 1989 0.75
113 Calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro. Arch Toxicol 1987 0.75
114 GM-CSF as adjuvant for immunotherapy with bispecific antibodies. Eur J Cancer 1999 0.75
115 Effect of rIFN-gamma on antibody-mediated cytotoxicity via human monocyte IgG Fc receptor II (CD32). Scand J Immunol 1992 0.75
116 CD89 (Fc alphaRI). J Biol Regul Homeost Agents 2001 0.75
117 Functional consequences of the interaction between T-cell antigen receptors and Fc gamma Rs on T cells. Immunol Lett 1995 0.75
118 Evaluation of Fc gamma receptor mediated T-cell activation by two purified CD3 x CD19 bispecific monoclonal antibodies with hybrid Fc domains. Ther Immunol 1994 0.75
119 PMN-derived proteases enhance the affinity of Fc gamma receptor II on myeloid cells, but not on B cells. Mol Immunol 1990 0.75
120 Lysis of murine B lymphoma cells by transgenic phagocytes via a human Fc gamma RI x murine MHC class II bispecific antibody. Cancer Immunol Immunother 1998 0.75