Published in Methods Enzymol on January 01, 1978
Orientation of electron transport activities in the membrane of intact glyoxysomes isolated from castor bean endosperm. Plant Physiol (1987) 1.02
Conversion and Distribution of Cobalamin in Euglena gracilis z, with Special Reference to Its Location and Probable Function within Chloroplasts. Plant Physiol (1984) 0.90
Purification and characterization of NADPH--cytochrome c reductase from the midgut of the southern armyworm (Spodoptera eridania). Biochem J (1979) 0.85
Manganese-enhanced biotransformation of atrazine by the white rot fungus Pleurotus pulmonarius and its correlation with oxidation activity. Appl Environ Microbiol (1996) 0.77
Blue Light-Reducible Cytochromes in Membrane Fractions from Neurospora crassa. Plant Physiol (1985) 0.75
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics (1996) 6.12
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol (1993) 4.92
Spectral studies of drug interaction with hepatic microsomal cytochrome. Mol Pharmacol (1967) 4.16
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol (1991) 3.73
The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. DNA (1989) 3.03
The P450 gene superfamily: recommended nomenclature. DNA (1987) 2.95
Function of cytochrome P-450 of microsomes. Fed Proc (1966) 2.57
A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1). Proc Natl Acad Sci U S A (2003) 2.13
Fractures in Flexner's foundation: recommended changes in medical education. FASEB J (1992) 2.01
The measurement of difference spectra: application to the cytochromes of microsomes. Methods Enzymol (1978) 1.93
Cytochrome P450 and the arachidonate cascade. FASEB J (1992) 1.85
Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid. Proc Natl Acad Sci U S A (1981) 1.69
Evidence for the participation of cytochrome b 5 in hepatic microsomal mixed-function oxidation reactions. Arch Biochem Biophys (1971) 1.63
Drug interaction with hepatic microsomal cytochrome. Mol Pharmacol (1966) 1.55
The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase. Arch Biochem Biophys (1983) 1.55
Metyrapone interaction with hepatic microsomal cytochrome P-450 from rats treated with phenobarbital. Biochem Biophys Res Commun (1969) 1.47
Studies of baker's yeast metabolism. II. The role of adenine nucleotides and inorganic phosphate in the control of respiration during alcohol oxidation. Arch Biochem Biophys (1967) 1.44
Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. Proc Natl Acad Sci U S A (1982) 1.31
The high-level expression in Escherichia coli of the membrane-bound form of human and rat cytochrome b5 and studies on their mechanism of function. Arch Biochem Biophys (1994) 1.29
A quantitative test for superoxide radicals produced in biological systems. Biochem J (1982) 1.22
Novel glutathione conjugates formed from epoxyeicosatrienoic acids (EETs). Arch Biochem Biophys (1985) 1.21
Temperature dependence of cytochrome P-450 reduction. A model for NADPH-cytochrome P-450 reductase:cytochrome P-450 interaction. J Biol Chem (1976) 1.20
Factors influencing the inhibitory effect of carbon monoxide on cytochrome P-450-catalyzed mixed function oxidation reactions. Ann N Y Acad Sci (1970) 1.17
Biochemical and genetic factors influencing drug metabolism. Influence of hepatic microsomal mixed function oxidation reactions on cellular metabolic control. Metabolism (1971) 1.17
High-level expression of functional human cytochrome P450 1A2 in Escherichia coli. FASEB J (1992) 1.15
A new spectral intermediate associated with cytochrome P-450 function in liver microsomes. Biochem Biophys Res Commun (1971) 1.14
Sex differences in drug metabolism by rat liver microsomes. Mol Pharmacol (1967) 1.12
Fatty acid monooxygenation by cytochrome P-450BM-3. J Biol Chem (1990) 1.12
Electron Transport in the Oxysome. Science (1963) 1.11
Cytochrome P-450 of liver microsomes--one pigment or many. Biochem Biophys Res Commun (1968) 1.09
Kinetic studies of temperature changes and oxygen uptake in a differential calorimeter: the heat of oxidation of NADH and succinate. Arch Biochem Biophys (1967) 1.09
Inhibition of rat liver microsomal cytochrome P-450 steroid hydroxylase reactions by imidazole antimycotic agents. Biochem Pharmacol (1986) 1.08
Spectroscopic studies on spinach ferredoxin and adrenodoxin. Biochemistry (1967) 1.07
The oxidative metabolism of arachidonic acid by purified cytochromes P-450. Biochem Biophys Res Commun (1981) 1.06
Microsomal electron transport reactions. 3. Cooperative interactions between reduced diphosphopyridine nucleotide and reduced triphosphopyridine nucleotide linked reactions. Arch Biochem Biophys (1971) 1.04
Mitochondrial malic enzyme: the source of reduced nicotinamide adenine dinucleotide phosphate for steroid hydroxylation in bovine adrenal cortex mitochondria. Arch Biochem Biophys (1969) 1.04
Differences in the mechanism of NADPH- and cumene hydroperoxide-supported reactions of cytochrome P-450. Arch Biochem Biophys (1980) 1.04
Induction of microsomal NADPH-cytochrome P-450 reductase and cytochrome P-450IVA1 (P-450LA omega) by dehydroepiandrosterone in rats: a possible peroxisomal proliferator. Cancer Res (1989) 1.03
Observations on the inhibitor sensitivity of the choline oxidation system. Arch Biochem Biophys (1966) 1.01
Studies of the DPNH-cytochrome b segment of the respiratory chain of baker's yeast. Biochem Biophys Res Commun (1966) 1.00
Drugs, alcohol and sex hormones: a molecular perspective of the receptivity of cytochrome P-450. Ann N Y Acad Sci (1973) 1.00
Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2. Drug Metab Dispos (1997) 0.98
Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17A and rat NADPH-P450 reductase. Arch Biochem Biophys (1994) 0.98
Purification, characterization, and cDNA cloning of an NADPH-cytochrome P450 reductase from mung bean. Proc Natl Acad Sci U S A (1993) 0.97
Lifetime of adrenal cytochrome P-450 as influenced by ACTH. Ann N Y Acad Sci (1973) 0.97
Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. Proc Natl Acad Sci U S A (1993) 0.97
On the inhibitory action of mersalyl on microsomal drug oxidation: a rigid organization of the electron transport chain. Arch Biochem Biophys (1971) 0.96
Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions. Biochemistry (2001) 0.96
Transformation of an arachidonic acid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450. Arch Biochem Biophys (1987) 0.95
Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function. Methods Enzymol (1991) 0.94
In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices. Drug Metab Dispos (1995) 0.94
Mitochondrial Structure and Function--A "Compostium". Science (1964) 0.94
The preparation of microsomal fractions of rodent respiratory tract and their characterization. Cancer Res (1974) 0.94
High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein. Proc Natl Acad Sci U S A (1992) 0.93
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase. J Clin Endocrinol Metab (1993) 0.93
The influence of deuterium oxide and organic solvents on the interaction of respiratory chain components. J Biol Chem (1966) 0.92
Exercise intolerance, lactic acidosis, and abnormal cardiopulmonary regulation in exercise associated with adult skeletal muscle cytochrome c oxidase deficiency. J Clin Invest (1989) 0.91
Fatty acid monooxygenation by P450BM-3: product identification and proposed mechanisms for the sequential hydroxylation reactions. Arch Biochem Biophys (1992) 0.91
Oxygen interaction with reduced cytochrome P-450. Hoppe Seylers Z Physiol Chem (1968) 0.91
On the use of nicotinamide in assays for microsomal mixed-function oxidase activity. Biochem Pharmacol (1967) 0.91
Microsomal electron transport reactions. II. The use of reduced triphosphopyridine nucleotide and-or reduced diphosphopyridine nucleotide for the oxidative N-demethylation of aminopyrine and other drug substrates. Arch Biochem Biophys (1971) 0.90
The reaction of phenylhydrazine with microsomal cytochrome P-450. Catalysis of heme modification. J Biol Chem (1982) 0.88
Involvement of HxuC outer membrane protein in utilization of hemoglobin by Haemophilus influenzae. Infect Immun (2001) 0.88
Spin state transitions of liver microsomal cytochrome P-450. Acta Biol Med Ger (1979) 0.87
Possible higher valence states of cytochrome P-450 during oxidative reactions. Biochem Biophys Res Commun (1974) 0.87
Reconstitution of the fatty acid hydroxylation function of cytochrome P-450BM-3 utilizing its individual recombinant hemo- and flavoprotein domains. J Biol Chem (1992) 0.87
The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. Arch Biochem Biophys (1996) 0.87
Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1. Proc Natl Acad Sci U S A (1995) 0.87
EPR measurements of substrate interaction with cytochrome P-450. Biochem Biophys Res Commun (1966) 0.87
CCl4-induced toxicity in isolated hepatocytes: the importance of direct solvent injury. Hepatology (1986) 0.85
Aldosterone synthesis by adrenal mitochondria. 3. Participation of cytochrome P-450. Arch Biochem Biophys (1967) 0.85
Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture. Endocrinology (1989) 0.85
Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes. Arch Biochem Biophys (1973) 0.85
Spectrophotometric studies of interactions between various substrates in their binding to microsomal cytochrome P-450. Biochem Biophys Res Commun (1969) 0.85
The role of oxygenated cytochrome P-450 and of cytochrome b5 in hepatic microsomal drug oxidations. Drug Metab Dispos (1974) 0.85
Heterogeneity of liver microsomal cytochrome P-450: the spectral characterization of reactants with reduced cytochrome P-450. Arch Biochem Biophys (1975) 0.83
The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein. Arch Biochem Biophys (1995) 0.83
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 0.83
Nonheme iron protein as a possible site of rotenone inhibition of mitochondrial NADH dehydrogenase. Arch Biochem Biophys (1969) 0.83
Studies on the molecular function of cytochrome P-450 during drug metabolism. Drug Metab Dispos (1974) 0.82
The contribution of the microsomal electron transport pathway to the oxidative metabolism of liver. Adv Enzyme Regul (1970) 0.82
The peroxidatic function of liver microsomal cytochrome P-450: comparison of hydrogen peroxide and NADPH-catalysed N-demethylation reactions. Xenobiotica (1984) 0.82
Engineering of proteolytically stable NADPH-cytochrome P450 reductase. Biochemistry (Mosc) (2005) 0.82
Expression of functional bovine cholesterol side chain cleavage cytochrome P450 (P450scc) in Escherichia coli. Arch Biochem Biophys (1991) 0.82
Testicular cytochrome P-450 and iron-sulfur protein as related to steroid metabolism. Ann N Y Acad Sci (1973) 0.82
Oxycytochrome P-450: its breakdown to superoxide for the formation of hydrogen peroxide. Acta Biol Med Ger (1979) 0.82
The mechanism of cumene hydroperoxide-dependent lipid peroxidation: the function of cytochrome P-450. Arch Biochem Biophys (1986) 0.81
Adrenal cells in tissue culture. V. On the specificity of the stimulation of 11beta-hydroxylation by adrenocorticotropin. J Biol Chem (1970) 0.81
Evidence for an inhibitory product-cytochrome P-450 complex generated during benzphetamine metabolism by liver microsomes. Life Sci (1973) 0.81
Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: comparison of three types of expression systems. Mutat Res (1999) 0.80
Oxygenated cytochrome P-450 as an intermediate in hydroxylation reactions. Biochem Soc Symp (1972) 0.80
Interaction of androgens with the adrenal mitochondrial cytochrome system. The influence of androgen treatment on the levels of cytochrome in rat adrenal cortical mitochondria and on substrate-induced spectral changes. Arch Biochem Biophys (1970) 0.79
Expression of a full-length cDNA encoding bovine adrenal cytochrome P450C21. Arch Biochem Biophys (1989) 0.79
The existence of a benzo(a)pyrene-3,6-quinone reductase in rat liver microsomal fractions. Biochem Biophys Res Commun (1978) 0.79
Chemistry of soluble and membrane-bound cytochrome P-450. Ann N Y Acad Sci (1975) 0.79
The interaction of steroids with liver microsomal cytochrome P-450--a general hypothesis. J Steroid Biochem (1976) 0.79
The "malate shuttle" and control of steroid hydroxylation in the adrenal cortex. Adv Enzyme Regul (1969) 0.79
Construction of plasmids and expression in Escherichia coli of enzymatically active fusion proteins containing the heme-domain of a P450 linked to NADPH-P450 reductase. Methods Enzymol (1996) 0.79
Kinetic studies of temperature changes and oxygen uptake concomitant with substrate oxidation by mitochondria: the enthalpy of succinate oxidation during ATP formation by mitochondria. Arch Biochem Biophys (1968) 0.78