Published in Ann Neurol on September 01, 1998
Baby STEPS: a giant leap for cell therapy in neonatal brain injury. Pediatr Res (2011) 2.02
Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. J Neurosci (2011) 1.64
2001 William Allan Award Address. From Down syndrome to the "human" in "human genetics". Am J Hum Genet (2001) 1.48
Neuronal death/survival signaling pathways in cerebral ischemia. NeuroRx (2004) 1.44
Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal (2010) 1.37
Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injury. Exp Neurol (2009) 1.31
Hyperoxia causes maturation-dependent cell death in the developing white matter. J Neurosci (2008) 1.30
Does inflammation after stroke affect the developing brain differently than adult brain? Dev Neurosci (2009) 1.30
Traumatic injury to the immature brain: inflammation, oxidative injury, and iron-mediated damage as potential therapeutic targets. NeuroRx (2006) 1.21
Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem (2005) 1.19
Mitochondrial network determines intracellular ROS dynamics and sensitivity to oxidative stress through switching inter-mitochondrial messengers. PLoS One (2011) 1.16
Genetic deletion of CD36 enhances injury after acute neonatal stroke. Ann Neurol (2012) 0.97
Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia. Br J Pharmacol (2008) 0.97
Inflammation in adult and neonatal stroke. Clin Neurosci Res (2006) 0.94
Stem cell therapy for neonatal hypoxic-ischemic encephalopathy. Front Neurol (2014) 0.89
Influence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging. Antioxid Redox Signal (2011) 0.89
Endoplasmic reticulum stress, inflammation, and perinatal brain damage. Pediatr Res (2009) 0.88
Gene therapy using SOD1 protects striatal neurons from experimental stroke. Neurosci Lett (2006) 0.87
The role of antioxidants in models of inflammation: emphasis on L-arginine and arachidonic acid metabolism. Inflammopharmacology (2005) 0.87
Glutathione peroxidase activity modulates recovery in the injured immature brain. Ann Neurol (2009) 0.86
Partial attenuation of cytotoxicity and apoptosis by SOD1 in ischemic renal epithelial cells. Apoptosis (2009) 0.85
Glutathione peroxidase overexpression causes aberrant ERK activation in neonatal mouse cortex after hypoxic preconditioning. Pediatr Res (2012) 0.84
The pentose phosphate pathway and pyruvate carboxylation after neonatal hypoxic-ischemic brain injury. J Cereb Blood Flow Metab (2014) 0.84
Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia. Int J Dev Neurosci (2007) 0.83
Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector. BMC Neurosci (2006) 0.83
Evaluation of autophagy using mouse models of brain injury. Biochim Biophys Acta (2009) 0.82
Role of antioxidant enzymes in redox regulation of N-methyl-D-aspartate receptor function and memory in middle-aged rats. Neurobiol Aging (2013) 0.82
Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury. J Neuroinflammation (2005) 0.82
ADVANCES IN THE CELL-BASED TREATMENT OF NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY. Future Neurol (2013) 0.82
Swim training does not protect mice from skeletal muscle oxidative damage following a maximum exercise test. Eur J Appl Physiol (2011) 0.81
Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism. Redox Biol (2015) 0.80
Neuroinflammation and neuroimmune dysregulation after acute hypoxic-ischemic injury of developing brain. Front Pediatr (2015) 0.77
Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia. Mol Med Rep (2014) 0.77
Pathophysiology and neuroprotection of global and focal perinatal brain injury: lessons from animal models. Pediatr Neurol (2015) 0.76
Iron metabolism, oxidative stress, and neonatal brain injury. Neural Regen Res (2016) 0.76
A model of Periventricular Leukomalacia (PVL) in neonate mice with histopathological and neurodevelopmental outcomes mimicking human PVL in neonates. PLoS One (2017) 0.75
SOD1 Overexpression Preserves Baroreflex Control of Heart Rate with an Increase of Aortic Depressor Nerve Function. Oxid Med Cell Longev (2015) 0.75
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet (1995) 7.17
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab Invest (1970) 6.44
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine (Baltimore) (1966) 6.15
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci U S A (1999) 3.96
Incorporation of 3H-uridine and 3H-uracil into RNA: a simple technique for the detection of mycoplasma contamination of cultured cells. Exp Cell Res (1974) 3.73
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest (1997) 3.45
A convenient method of preparing polyacrylamide gels for liquid scintillation spectrometry. Anal Biochem (1968) 3.14
Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem (1998) 3.00
Primary afferent tachykinins are required to experience moderate to intense pain. Nature (1998) 2.97
Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc Natl Acad Sci U S A (1999) 2.91
Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem (1999) 2.91
A unique set of polypeptides is induced by gamma interferon in addition to those induced in common with alpha and beta interferons. Nature (1983) 2.68
Free radical pathways in CNS injury. J Neurotrauma (2000) 2.52
Seizure-associated brain injury in term newborns with perinatal asphyxia. Neurology (2002) 2.49
Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci (1998) 2.39
Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. AJNR Am J Neuroradiol (1998) 2.35
Chloroplast DNA codes for the primary structure of the large subunit of fraction I protein. Biochim Biophys Acta (1972) 2.34
Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. Proc Natl Acad Sci U S A (1998) 2.32
Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proc Natl Acad Sci U S A (1996) 2.32
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. J Biol Chem (1998) 2.28
LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J Immunol (2000) 2.27
Early CT reevaluation after empiric praziquantel therapy in neurocysticercosis. Neurology (1989) 2.27
Crystalline fraction I protein: preparation in large yield. Science (1972) 2.09
MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol (2006) 2.00
Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion. J Neurosci (1998) 1.99
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke (1994) 1.99
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A (2000) 1.94
Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain. Ann Neurol (2000) 1.93
Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction. J Cereb Blood Flow Metab (1999) 1.87
MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats. Clin Exp Pharmacol Physiol (2008) 1.84
Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci (1997) 1.84
Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab (2001) 1.83
Strain-related brain injury in neonatal mice subjected to hypoxia-ischemia. Brain Res (1998) 1.82
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc Natl Acad Sci U S A (1991) 1.82
Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. J Cereb Blood Flow Metab (2001) 1.81
Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. Am J Hum Genet (2001) 1.80
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J Neurosci (1992) 1.79
Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. J Gerontol A Biol Sci Med Sci (2000) 1.74
Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis. Neurobiol Dis (2001) 1.72
Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc Natl Acad Sci U S A (2001) 1.72
Cerebral palsy: MR findings in 40 patients. AJNR Am J Neuroradiol (1992) 1.71
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am J Physiol Heart Circ Physiol (2001) 1.71
Microlissencephaly: a heterogeneous malformation of cortical development. Neuropediatrics (1998) 1.65
Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion. Brain Res (1999) 1.62
Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nat Med (1995) 1.61
Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes. Gut (1996) 1.60
Child care practices and cot death in Hong Kong. N Z Med J (1996) 1.60
Organized medical genetics at a crossroad. Am J Hum Genet (1992) 1.59
Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci (1999) 1.56
Perinatal stroke in term infants with neonatal encephalopathy. Neurology (2004) 1.55
Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus. J Biol Chem (2000) 1.55
Overexpression of copper/zinc superoxide dismutase: a novel cause of murine muscular dystrophy. Ann Neurol (1998) 1.54
Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Dev Dyn (2004) 1.52
Prenatal genetic diagnosis in 3000 amniocenteses. N Engl J Med (1979) 1.50
Effects of III-IV linker mutations on human heart Na+ channel inactivation gating. Circ Res (1994) 1.50
Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Crit Care Med (2000) 1.48
Familial acrocephalosyndactyly (Pfeiffer syndrome). Am J Roentgenol Radium Ther Nucl Med (1972) 1.46
Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. Neurology (2011) 1.45
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease. Cell Death Differ (2004) 1.44
Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis. J Neurosci (2001) 1.41
Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys (1997) 1.40
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Arch Biochem Biophys (1999) 1.39
Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. J Neurosci (1999) 1.39
Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain. Stroke (2003) 1.39
Evidence for expression of the paternal genome in the two-cell mouse embryo. Nature (1981) 1.39
Amelioration of vasospasm after subarachnoid hemorrhage in transgenic mice overexpressing CuZn-superoxide dismutase. Stroke (1999) 1.37
Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radic Biol Med (2001) 1.36
Brain injury after perinatal hypoxia-ischemia is exacerbated in copper/zinc superoxide dismutase transgenic mice. Pediatr Res (1996) 1.36
Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. J Neurochem (2001) 1.35
The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J Neurosci (2000) 1.34
Hereditary macrothrombocytopathia, nephritis and deafness. Am J Med (1972) 1.34
Mycoplasma contamination of cultured amniotic fluid cells: potential hazard to prenatal chromosomal diagnosis. Science (1974) 1.32
Early prediction of neurologic outcome after perinatal depression. Pediatr Neurol (1999) 1.32
Severe pulmonary involvement in adult Gaucher's disease. Report of three cases and review of the literature. Am J Med (1977) 1.31
Hereditary dysplasia of bone with kyphoscoliosis, contractures, and abnormally shaped ears. J Pediatr (1968) 1.30
Molecular markers for the agouti coat color locus of the mouse. Genetics (1987) 1.30
The normal neonatal brain: MR imaging, diffusion tensor imaging, and 3D MR spectroscopy in healthy term neonates. AJNR Am J Neuroradiol (2007) 1.30
The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome. Hum Mol Genet (2004) 1.29
Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neuropharmacology (1999) 1.29
Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-Plasmid/Liposome (SOD2-PL) intratracheal gene therapy. Radiat Res (2000) 1.28
Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos. Nature (1978) 1.27
Proton MR spectroscopy for the evaluation of brain injury in asphyxiated, term neonates. AJNR Am J Neuroradiol (1999) 1.27
X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature (1978) 1.27
Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatr Res (2000) 1.26
Non-randomness of amino-acid changes in the evolution of homologous proteins. Nature (1967) 1.24
Who should do genetic counseling, and under what circumstances? Birth Defects Orig Artic Ser (1973) 1.23