Signaling by integrin receptors.

Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol (2001) 3.32

Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells. Mol Cell Biol (2001) 2.72

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix. Mol Cell Biol (2002) 1.60

Regulation of c-SRC activity and function by the adapter protein CAS. Mol Cell Biol (2000) 1.40

The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene (2008) 1.38

Role of integrin receptors for fibronectin, collagen and laminin in the regulation of ovarian carcinoma functions in response to a matrix microenvironment. Clin Exp Metastasis (2005) 1.30

ARK5 is a tumor invasion-associated factor downstream of Akt signaling. Mol Cell Biol (2004) 1.29

"...those left behind." Biology and oncology of invasive glioma cells. Neoplasia (1999) 1.24

A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis. Clin Exp Metastasis (2004) 1.23

Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase. Mol Cell Biol (2008) 1.21

The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease. Arthritis Res Ther (2008) 1.20

Two independent signaling pathways mediate the antiapoptotic action of macrophage-stimulating protein on epithelial cells. Mol Cell Biol (2000) 1.19

HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3. PLoS One (2010) 1.14

Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation. J Biol Chem (2010) 1.08

Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal. Stem Cell Res (2011) 1.07

Redox control of vascular smooth muscle migration. Antioxid Redox Signal (2010) 1.06

Regulation of Rho and Rac signaling to the actin cytoskeleton by paxillin during Drosophila development. Mol Cell Biol (2005) 1.05

Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models. PLoS One (2013) 1.04

alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation. Am J Pathol (2009) 1.01

Novel near-infrared fluorescent integrin-targeted DFO analogue. Bioconjug Chem (2007) 0.96

Cyclin-dependent kinase 5 promotes pancreatic β-cell survival via Fak-Akt signaling pathways. Diabetes (2011) 0.94

Beta1-integrin and PTEN control the phosphorylation of protein kinase C. Biochem J (2000) 0.94

Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel. Br J Cancer (2011) 0.93

Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12. Oncogene (2012) 0.92

Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines. Regul Pept (2007) 0.91

Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis. J Biol Chem (2014) 0.88

Regulation of protumorigenic pathways by insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis. Mol Cancer (2013) 0.88

Involvement of host cell integrin α2 in Cryptosporidium parvum infection. Infect Immun (2012) 0.87

Overexpression of osteopontin and integrin αv in laryngeal and hypopharyngeal carcinomas associated with differentiation and metastasis. J Cancer Res Clin Oncol (2011) 0.86

Cooperative activation of Src family kinases by SH3 and SH2 ligands. Cancer Lett (2007) 0.86

Integrin β1 regulates leiomyoma cytoskeletal integrity and growth. Matrix Biol (2012) 0.85

Altered expression pattern of integrin alphavbeta3 correlates with actin cytoskeleton in primary cultures of human breast cancer. Cancer Cell Int (2007) 0.85

Acurhagin-C, an ECD disintegrin, inhibits integrin alphavbeta3-mediated human endothelial cell functions by inducing apoptosis via caspase-3 activation. Br J Pharmacol (2010) 0.84

Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation. Dev Biol (2010) 0.84

Nonprofessional phagocytic cell receptors involved in Staphylococcus aureus internalization. Biomed Res Int (2014) 0.82

Incorporation of Fucoidan in β-Tricalcium phosphate-Chitosan scaffold prompts the differentiation of human bone marrow stromal cells into osteogenic lineage. Sci Rep (2016) 0.82

Syk tyrosine 317 negatively regulates osteoclast function via the ubiquitin-protein isopeptide ligase activity of Cbl. J Biol Chem (2009) 0.81

Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context. Oncotarget (2016) 0.80

Induction of apoptosis and the regulation of ErbB signaling by laminarin in HT-29 human colon cancer cells. Int J Mol Med (2013) 0.80

Spatial organization of cell-adhesive ligands for advanced cell culture. Biotechnol J (2013) 0.80

Enhanced expression of trophinin promotes invasive and metastatic potential of human gallbladder cancer cells. J Cancer Res Clin Oncol (2008) 0.79

Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation. J Oncol (2011) 0.79

Innate Immunity and Biomaterials at the Nexus: Friends or Foes. Biomed Res Int (2015) 0.78

Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling Pathway. PLoS One (2015) 0.78

Cytoskeleton reorganization mediates alpha6beta1 integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cells. Reprod Biol Endocrinol (2005) 0.78

Design, Assessment, and in vivo Evaluation of a Computational Model Illustrating the Role of CAV1 in CD4(+) T-lymphocytes. Front Immunol (2014) 0.78

Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells. Cancer Lett (2017) 0.76

Epithelial cell surface sites involved in the polyvalent adherence of Porphyromonas gingivalis: a convincing role for neuraminic acid and glucuronic acid. Infect Immun (2003) 0.76

A HIC-5- and KLF4-dependent mechanism transactivates p21(Cip1) in response to anchorage loss. J Biol Chem (2012) 0.76

Redox regulation of the actin cytoskeleton and its role in the vascular system. Free Radic Biol Med (2017) 0.75

RhoGDI2 is associated with HGF-mediated tumor invasion through VEGF in stomach cancer. Clin Exp Metastasis (2014) 0.75

SCH 51344 inhibits ras transformation by a novel mechanism. Cancer Res (1995) 0.92