PubRank

K M Murphy

Author PubWeight™ 206.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 1993 19.80
2 Functional diversity of helper T lymphocytes. Nature 1996 18.09
3 Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 1995 6.09
4 Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 1998 5.75
5 Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev 2000 5.61
6 Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997 5.56
7 Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A 1992 5.55
8 Dendritic cell regulation of TH1-TH2 development. Nat Immunol 2000 5.13
9 The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model. J Exp Med 1995 4.21
10 Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 2000 3.93
11 Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development. Science 1996 3.60
12 Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nat Immunol 2000 3.38
13 Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 1995 3.37
14 T cell genetic background determines default T helper phenotype development in vitro. J Exp Med 1995 3.18
15 Regulation of interleukin 12 p40 expression through an NF-kappa B half-site. Mol Cell Biol 1995 3.10
16 Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science 1993 2.93
17 IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. Nat Immunol 2001 2.81
18 Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development. J Immunol 1996 2.68
19 Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity 1995 2.64
20 Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. Int Immunol 1993 2.36
21 Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol Cell Biol 1993 2.30
22 Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway. Infect Immun 1996 2.23
23 Induction of interferon-gamma production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation. Eur J Immunol 1999 2.14
24 Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets. Science 1995 1.90
25 Heterogeneity of single cell cytokine gene expression in clonal T cell populations. J Exp Med 1994 1.88
26 GATA-3-dependent enhancer activity in IL-4 gene regulation. J Immunol 1998 1.81
27 Pathogen-induced Th1 phenotype development in CD4+ alpha beta-TCR transgenic T cells is macrophage dependent. Int Immunol 1993 1.80
28 Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc Natl Acad Sci U S A 1996 1.59
29 A unitary mechanism of calcium antagonist drug action. Proc Natl Acad Sci U S A 1983 1.53
30 Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells. J Exp Med 1999 1.52
31 Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development. Proc Natl Acad Sci U S A 1995 1.51
32 Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. Mol Cell Biol 2001 1.43
33 Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells. J Immunol 1998 1.43
34 Calcium antagonist receptor binding sites labeled with [3H]nitrendipine. Eur J Pharmacol 1982 1.41
35 Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1. Blood 1999 1.41
36 IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol 1998 1.38
37 T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development. J Immunol 1997 1.37
38 Technique for securing guide wires in cannulated screw systems. Am J Orthop (Belle Mead NJ) 1996 1.37
39 [3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists. Proc Natl Acad Sci U S A 1982 1.37
40 Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999 1.35
41 Structure and specificity of GATA proteins in Th2 development. Mol Cell Biol 2001 1.34
42 The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway. Proc Natl Acad Sci U S A 1999 1.33
43 ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma. Proc Natl Acad Sci U S A 2001 1.29
44 Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. J Exp Med 2001 1.26
45 Unexpected characteristics of the IFN-gamma reporters in nontransformed T cells. J Immunol 2001 1.25
46 Constitutive expression of the urokinase plasminogen activator gene in murine RAW264 macrophages involves distal and 5' non-coding sequences that are conserved between mouse and pig. Nucleic Acids Res 1991 1.24
47 Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes. Proc Natl Acad Sci U S A 1992 1.23
48 Splenomegaly, hypersplenism and coagulation abnormalities in liver disease. Baillieres Best Pract Res Clin Gastroenterol 2000 1.21
49 Compliance with timolol treatment in glaucoma. Eye (Lond) 1998 1.21
50 Racial and state differences in the designation of advance directives in nursing home residents. J Am Geriatr Soc 2001 1.20
51 An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3. J Exp Med 2001 1.18
52 The RAI-PC: an assessment instrument for palliative care in all settings. Am J Hosp Palliat Care 2003 1.18
53 A description of cutaneous-subcutaneous pythiosis in fifteen dogs. Med Mycol 1999 1.17
54 Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis. Endocrinology 1985 1.14
55 Type I interferons and T helper development. Immunol Today 2000 1.14
56 Tissue heterogeneity of calcium channel antagonist binding sites labeled by [3H]nitrendipine. Mol Pharmacol 1984 1.13
57 Regulation of interleukin-12 signalling during T helper phenotype development. Adv Exp Med Biol 1996 1.13
58 Stability and commitment in T helper cell development. Curr Opin Immunol 2001 1.11
59 Transmission of a T-cell lymphoma by allogeneic bone marrow transplantation. N Engl J Med 2001 1.10
60 Peripheral-type benzodiazepine receptors in the central nervous system: localization to olfactory nerves. J Neurosci 1984 1.10
61 Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell. J Immunol 1993 1.09
62 Heterogeneity of adenosine A1 receptor binding in brain tissue. Mol Pharmacol 1982 1.07
63 Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists. Proc Natl Acad Sci U S A 1983 1.07
64 Recruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2. J Biol Chem 2000 1.05
65 Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation. Mol Cell Biol 2000 1.04
66 TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization. J Immunol 1999 1.04
67 Addition of aerobic exercise to dietary weight loss preferentially reduces abdominal adipocyte size. Int J Obes (Lond) 2006 1.02
68 Tissue-specific targeting of cytokine unresponsiveness in transgenic mice. Immunity 1995 1.02
69 Tpm1, a locus controlling IL-12 responsiveness, acts by a cell-autonomous mechanism. J Immunol 1999 0.98
70 Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development. Mol Cell Biol 1999 0.97
71 Genetic control of interleukin 12 responsiveness: implications for disease pathogenesis. J Mol Med (Berl) 1997 0.92
72 Adenosine receptors in rat testes: labeling with 3H-cyclohexyladenosine. Life Sci 1981 0.91
73 The human T-cell leukemia virus type-1 Tax protein regulates the activity of the IkappaB kinase complex. J Biol Chem 1999 0.91
74 Reduced visual acuity in both eyes of monocularly deprived kittens following a short or long period of reverse occlusion. J Neurosci 1987 0.90
75 Murine AIDS superantigen reactivity of the T cells bearing V beta 5 T cell antigen receptor. J Immunol 1992 0.90
76 Autoradiographic visualization of [3H]nitrendipine binding sites in rat brain: localization to synaptic zones. Eur J Pharmacol 1982 0.88
77 Flexor tendon entrapment in ulnar shaft fractures. Clin Orthop Relat Res 1996 0.88
78 Autoradiographic localization of atriopeptin III receptors in rat kidney. Eur J Pharmacol 1985 0.87
79 Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development. J Immunol 1997 0.87
80 MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells. Br J Cancer 2001 0.86
81 Effects of dietary protein and salt on rat renal osmolytes: covariation in urea and GPC contents. Am J Physiol 1992 0.86
82 Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts. Am J Transplant 2007 0.85
83 A computational model for the overall pattern of ocular dominance. J Neurosci 1991 0.84
84 The process of restructuring and the treatment of obesity in women. Health Care Women Int 2002 0.84
85 Humerus shaft fractures in young children: accident or abuse? J Pediatr Orthop 1997 0.83
86 Genetics of the FANCA gene in familial pancreatic cancer. J Med Genet 2004 0.82
87 Characterization of the inflammatory infiltrate during IgE-mediated late phase reactions in the skin of normal and atopic dogs. Vet Dermatol 2001 0.82
88 Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group. Cancer Chemother Pharmacol 2011 0.81
89 Bilateral amblyopia after a short period of reverse occlusion in kittens. Nature 1986 0.81
90 Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice. J Neurosci Res 2002 0.81
91 Phorbol ester receptors: autoradiographic identification in the developing rat. Science 1983 0.81
92 Loci influencing development of Th responses. Identification from in vitro analysis. Microbes Infect 1999 0.80
93 Efficacy of cyclosporine for treatment induction of canine pemphigus foliaceus. Vet Rec 2003 0.80
94 Regulation of interleukin-12 signal transduction during T helper phenotype development. Res Immunol 1996 0.79
95 The permanence of the visual recovery that follows reverse occlusion of monocularly deprived kittens. Invest Ophthalmol Vis Sci 1984 0.79
96 Analysis of the postnatal growth of visual cortex. Vis Neurosci 1998 0.79
97 Bcl-2 inhibits early apoptotic events and reveals post-mitotic multinucleation without affecting cell cycle arrest in human epithelial tumor cells exposed to etoposide. Cancer Chemother Pharmacol 1999 0.78
98 Regulatory role of IL4 and other cytokines in T helper cell development in an alpha beta TCR transgenic mouse system. Res Immunol 1993 0.78
99 Adenosine receptor localization in rat testes: biochemical and autoradiographic evidence for association with spermatocytes. Endocrinology 1983 0.78
100 A pilot open trial evaluating the efficacy of low-dose aminopterin in the canine homologue of human atopic dermatitis. Br J Dermatol 2007 0.78
101 Neuroanatomic and behavioral traits for autistic disorders in age-specific restricted index selection mice. Neuroscience 2011 0.78
102 Autoradiographic localization of calcium channel antagonist receptors in rat brain with [3H]nitrendipine. Brain Res 1985 0.78
103 Patchy distribution of NMDAR1 subunit immunoreactivity in developing visual cortex. J Neurosci 1998 0.77
104 Nodose ganglionectomy selectively reduces muscarinic cholinergic and delta opioid binding sites in the dorsal vagal complex of the cat. Neuroscience 1989 0.76
105 Bullous systemic lupus erythematosus (type I) in a dog. Vet Rec 1999 0.76
106 Labile nature of the visual recovery promoted by reverse occlusion in monocularly deprived kittens. Proc Natl Acad Sci U S A 1984 0.76
107 Experience-dependent development of NMDAR1 subunit expression in the lateral geniculate nucleus. Vis Neurosci 1999 0.76
108 Effect of dibenzanthracene on transplantable mammary adenofibroma of the white rat. Am J Pathol 1941 0.75
109 Molecular mechanisms in T helper phenotype development. Springer Semin Immunopathol 1999 0.75
110 The functional genomics experience (are you experienced?). Nat Immunol 2001 0.75
111 Calcium channel blockade: possible explanation for thioridazine's peripheral side effects. Am J Psychiatry 1984 0.75
112 Solvent-detergent plasma as replacement therapy in a pregnant patient with factor V deficiency. J Matern Fetal Neonatal Med 2004 0.75
113 Primary synovial sarcoma of the kidney. A case report with pathologic appraisal investigation and literature review. Pathologica 2011 0.75
114 Endotracheal bretylium tosylate in a canine model. Ann Emerg Med 1984 0.75
115 Studies on voltage-operated calcium channels using radioligands. Cold Spring Harb Symp Quant Biol 1983 0.75
116 Immunology at 2000. Immunity 1999 0.75
117 Myocardial muscarinic acetylcholine receptor: choline and tris unmask heterogeneity of antagonist binding sites. Biochem Biophys Res Commun 1982 0.75
118 Caffeine actions and adenosine. Psychopharmacol Bull 1984 0.75
119 A simple sensitive radioreceptor assay for calcium antagonist drugs. Life Sci 1983 0.75
120 The neuropharmacology of emesis: the role of receptors in neuromodulation of nausea and vomiting. Can J Physiol Pharmacol 1990 0.75
121 Displaced odontoid fracture in a 9-month-old child. Am J Emerg Med 1999 0.75
122 Risk management tips for dentists. J Md State Dent Assoc 1992 0.75
123 Interactional styles of parents following the birth of a high-risk infant. J Pediatr Nurs 1990 0.75
124 Obligatory role of a Tris/choline allosteric site in guanine nucleotide regulation of [3H]-L-QNB binding to muscarinic acetylcholine receptors. Biochem Biophys Res Commun 1983 0.75
125 Reporting medical neglect effectively: a guide for nurse practitioners working with child protective services. Nurse Pract Forum 2000 0.75
126 Differential interaction of guanabenz with receptor binding sites in rat brain and kidney. Res Commun Chem Pathol Pharmacol 1989 0.75
127 Separation of CD4+ functional responses by peptide dose in Th1 and Th2 subsets expressing the same transgenic antigen receptor. Cell Immunol 1993 0.75
128 Clinical guidelines: a defense in medical malpractice suits. Physician Exec 1995 0.75
129 C-arm manipulation using a sterile disposable lamp handle. Am J Orthop (Belle Mead NJ) 1997 0.75
130 Development of the visual callosal cell distribution in the rat: mature features are present at birth. Vis Neurosci 1997 0.75
131 Detection of acute synthetic vascular graft infection with 111In-labeled leukocyte scanning: an animal study. AJR Am J Roentgenol 1985 0.75