Published in J Exp Med on November 01, 1995
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest (1999) 8.38
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med (2000) 6.45
How are T(H)2-type immune responses initiated and amplified? Nat Rev Immunol (2010) 4.34
Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med (2003) 3.41
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell (2013) 3.22
Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose. Immunity (2009) 2.61
Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med (1997) 2.59
Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection. J Exp Med (1997) 2.40
Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med (2000) 2.36
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med (2009) 2.34
Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J Clin Invest (1998) 2.27
Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc Natl Acad Sci U S A (1998) 2.26
Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge. J Virol (1998) 2.21
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med (2010) 2.20
Vaccine- and antigen-dependent type 1 and type 2 cytokine induction after primary vaccination of infants with whole-cell or acellular pertussis vaccines. Infect Immun (1997) 2.03
Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunol Rev (2009) 2.00
New insights into the differentiation and function of T follicular helper cells. Nat Rev Immunol (2009) 1.92
Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. J Exp Med (2001) 1.90
Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells. J Exp Med (1997) 1.87
CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med (2003) 1.82
Cathepsin S activity regulates antigen presentation and immunity. J Clin Invest (1998) 1.76
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med (1996) 1.68
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. J Clin Invest (2007) 1.67
Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences. Infect Immun (1999) 1.63
Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol (2007) 1.59
A two-step, two-signal model for the primary activation of precursor helper T cells. Proc Natl Acad Sci U S A (1999) 1.58
CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells. Proc Natl Acad Sci U S A (2009) 1.56
Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment. Proc Natl Acad Sci U S A (2006) 1.54
T-helper-cell cytokines in the early evolution of murine Lyme arthritis. Infect Immun (1997) 1.51
T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation. Proc Natl Acad Sci U S A (1999) 1.46
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J Clin Invest (2001) 1.43
A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens. Proc Natl Acad Sci U S A (1997) 1.33
Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection. J Virol (1998) 1.33
Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells. J Exp Med (2004) 1.31
IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites. J Immunol (2005) 1.29
Antigen-pulsed CD8alpha+ dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node. J Exp Med (1999) 1.28
T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo. Immunity (2014) 1.28
IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells. Cell Immunol (2009) 1.26
Insights into the initiation of type 2 immune responses. Immunology (2011) 1.25
A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation. J Clin Invest (2004) 1.24
Limited role of CD28-mediated signals in T helper subset differentiation. J Exp Med (1996) 1.21
CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responses. Proc Natl Acad Sci U S A (1998) 1.21
Lysosomal cathepsin B plays an important role in antigen processing, while cathepsin D is involved in degradation of the invariant chain inovalbumin-immunized mice. Immunology (2000) 1.18
CD4+ T-helper-cell responses in mice with low-level Candida albicans infection. Infect Immun (1996) 1.18
Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope. J Exp Med (1999) 1.17
Thymic selection pathway regulates the effector function of CD4 T cells. J Exp Med (2007) 1.15
Regulation of T cell priming by lymphoid stroma. PLoS One (2011) 1.14
Quantitative events determine the differentiation and function of helper T cells. Nat Immunol (2011) 1.13
Annexin-1 modulates T-cell activation and differentiation. Blood (2006) 1.10
Glomerulonephritis, Th1 and Th2: what's new? Clin Exp Immunol (2005) 1.10
Glucocorticoids attenuate T cell receptor signaling. J Exp Med (2001) 1.10
Functional plasticity of an antigen-specific memory CD4 T cell population. Proc Natl Acad Sci U S A (2002) 1.10
Substrate rigidity regulates human T cell activation and proliferation. J Immunol (2012) 1.09
HLA-G has a concentration-dependent effect on the generation of an allo-CTL response. Immunology (2000) 1.07
Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. J Immunol (2010) 1.06
Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein. J Exp Med (1997) 1.06
Helper T-cell identity and evolution of differential transcriptomes and epigenomes. Immunol Rev (2013) 1.05
Induction of apoptosis and T helper 2 (Th2) responses correlates with peptide affinity for the major histocompatibility complex in self-reactive T cell receptor transgenic mice. J Exp Med (1997) 1.04
Studies of T-cell activation in chronic inflammation. Arthritis Res (2002) 1.04
Both exogenous and endogenous interleukin-10 affects the maturation of bone-marrow-derived dendritic cells in vitro and strongly influences T-cell priming in vivo. Immunology (2002) 1.04
Regulation of TH17 cell differentiation by innate immune signals. Cell Mol Immunol (2012) 1.03
The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. J Clin Invest (2004) 1.03
Omenn syndrome: a disorder of Rag1 and Rag2 genes. J Clin Immunol (1999) 1.03
T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex. J Exp Med (2000) 1.02
Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)--relation to Th1- and Th2-derived cytokines. Clin Exp Immunol (1999) 1.02
Prenatal immune priming in onchocerciasis-onchocerca volvulus-specific cellular responsiveness and cytokine production in newborns from infected mothers. Clin Exp Immunol (1999) 1.02
Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia. Infect Immun (2005) 1.01
IL-4: role in disease and regulation of production. Clin Exp Immunol (1998) 1.00
The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model. J Exp Med (1999) 0.98
Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses. J Exp Med (2000) 0.98
A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells. BMC Syst Biol (2012) 0.97
Quantifying crosstalk among interferon-γ, interleukin-12, and tumor necrosis factor signaling pathways within a TH1 cell model. Sci Signal (2012) 0.97
Preferential production of interferon-gamma by CD4+ T cells expressing the homing receptor integrin alpha4/beta7. Immunology (2001) 0.96
Persistence of peptide-induced CD4+ T cell anergy in vitro. J Exp Med (1998) 0.96
Intercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cells. Proc Natl Acad Sci U S A (1999) 0.95
Nanoscale artificial antigen presenting cells for T cell immunotherapy. Nanomedicine (2013) 0.95
Coxsackievirus B3-induced myocarditis: infection of females during the estrus phase of the ovarian cycle leads to activation of T regulatory cells. Virology (2008) 0.95
Polarized helper-T-cell responses against Leishmania major in the absence of B cells. Infect Immun (1999) 0.94
Altered Th1/Th2 commitment in human CD4+ T cells with ageing. Clin Exp Immunol (2000) 0.94
Anti-interleukin-4 modulation of the Th2 polarized response to the parasitic nematode Brugia pahangi. Infect Immun (1996) 0.94
Phenotypic models of T cell activation. Nat Rev Immunol (2014) 0.94
Altered T-cell receptor signaling in the pathogenesis of allergic disease. J Allergy Clin Immunol (2011) 0.92
Effect of different sensitizing doses of antigen in a murine model of atopic asthma. Clin Exp Immunol (1999) 0.92
Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines. J Immunol (2014) 0.92
Differential regulation of Th1 and Th2 cells by p91-110 and p21-40 peptides of the 16-kD alpha-crystallin antigen of Mycobacterium tuberculosis. Clin Exp Immunol (1998) 0.91
Immunological synapse: a multi-protein signalling cellular apparatus for controlling gene expression. Immunology (2010) 0.91
Contribution of conformational stability of hen lysozyme to induction of type 2 T-helper immune responses. Immunology (2001) 0.91
Peptide-based immunotherapy of autoimmunity: a path of puzzles, paradoxes and possibilities. Immunology (2001) 0.90
TCR signal quantity and quality in CD4(+) T cell differentiation. Trends Immunol (2014) 0.90
T cell immunity using transgenic B lymphocytes. Proc Natl Acad Sci U S A (2004) 0.89
Immunomodulatory dendritic cells require autologous serum to circumvent nonspecific immunosuppressive activity in vivo. Blood (2005) 0.89
Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy. J Exp Med (1999) 0.89
The modulatory effects of lipopolysaccharide-stimulated B cells on differential T-cell polarization. Immunology (2008) 0.89
Dendritic cell subsets in type 1 diabetes: friend or foe? Front Immunol (2013) 0.88
WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts. J Leukoc Biol (2015) 0.88
Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci U S A (2004) 0.87
Gammadelta T cells assist alphabeta T cells in the adoptive transfer of contact hypersensitivity to para-phenylenediamine. Clin Exp Immunol (2001) 0.87
The phenotype of type 1 and type 2 CD8+ T cells activated in vitro is affected by culture conditions and correlates with effector activity. Immunology (2005) 0.87
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science (1993) 19.80
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature (1985) 11.55
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med (1993) 8.76
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med (1992) 8.27
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J Exp Med (1992) 7.80
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Exp Med (1990) 7.09
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J Exp Med (1990) 6.19
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci U S A (1993) 6.12
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol (1995) 6.09
Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol (1989) 5.92
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A (1992) 5.55
Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu Rev Immunol (1992) 4.92
Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. Science (1992) 3.59
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation. J Exp Med (1994) 2.85
Role of cytokines in determining T-lymphocyte function. Curr Opin Immunol (1994) 2.83
The relationship between humoral and cell-mediated immunity. Transplant Rev (1972) 2.43
Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol (1994) 2.02
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur J Immunol (1993) 1.92
Heterogeneity of single cell cytokine gene expression in clonal T cell populations. J Exp Med (1994) 1.88
Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J Exp Med (1995) 1.44
A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL-4-secreting cells. J Immunol (1994) 1.41
Bee venom phospholipase A2-specific T cell clones from human allergic and non-allergic individuals: cytokine patterns change in response to the antigen concentration. Eur J Immunol (1992) 1.33
B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med (1987) 1.17
Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 25.63
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science (1993) 19.80
Functional diversity of helper T lymphocytes. Nature (1996) 18.09
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 16.28
IL-10 inhibits cytokine production by activated macrophages. J Immunol (1991) 13.13
A physical map of the human genome. Nature (2001) 12.39
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04
Interleukin-10. Annu Rev Immunol (1993) 10.14
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat Immunol (2001) 8.31
Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J (2006) 6.34
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol (1995) 6.09
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity (1998) 5.75
Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev (2000) 5.61
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med (1997) 5.56
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A (1992) 5.55
Dendritic cell regulation of TH1-TH2 development. Nat Immunol (2000) 5.13
The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J Immunol (1988) 4.38
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J Exp Med (1995) 4.12
1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol (2001) 4.06
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity (2000) 3.93
Biological properties of interleukin 10. Immunol Today (1992) 3.62
Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development. Science (1996) 3.60
IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. Immunity (1997) 3.60
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol (2005) 3.48
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J Exp Med (1996) 3.41
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nat Immunol (2000) 3.38
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med (1995) 3.37
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature (1994) 3.31
T cell genetic background determines default T helper phenotype development in vitro. J Exp Med (1995) 3.18
Regulation of interleukin 12 p40 expression through an NF-kappa B half-site. Mol Cell Biol (1995) 3.10
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science (1993) 2.93
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation. J Exp Med (1994) 2.85
IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. Nat Immunol (2001) 2.81
Collective bulk carrier delocalization driven by electrostatic surface charge accumulation. Nature (2012) 2.80
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development. J Immunol (1996) 2.68
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells. J Exp Med (2000) 2.68
Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Nat Immunol (2000) 2.66
Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity (1995) 2.64
Biological properties of interleukin 10. J Clin Immunol (1992) 2.50
Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev (1991) 2.49
Eosinophil differentiation factor also has B-cell growth factor activity: proposed name interleukin 4. Proc Natl Acad Sci U S A (1986) 2.47
Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. Int Immunol (1993) 2.36
Intraductal papillary mucinous tumors of the pancreas comprise 2 clinical subtypes: differences in clinical characteristics and surgical management. Arch Surg (1999) 2.33
The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J Immunol (1998) 2.32
Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol Cell Biol (1993) 2.30
Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature (1996) 2.30
Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. J Exp Med (1994) 2.23
Endobronchial ultrasound: new insight for the diagnosis of sarcoidosis. Eur Respir J (2007) 2.23
Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway. Infect Immun (1996) 2.23
Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity (1999) 2.21
Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. Proc Natl Acad Sci U S A (1995) 2.19
Induction of interferon-gamma production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation. Eur J Immunol (1999) 2.14
CD8+ T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection. Eur J Immunol (1997) 2.12
Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS. Neurology (2011) 2.09
The role of IL-10 in immune regulation during M. tuberculosis infection. Mucosal Immunol (2011) 2.09
Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice. J Exp Med (2001) 2.07
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness. Nat Genet (2001) 2.06
Differential effect of IL-10 on dendritic cell-induced T cell proliferation and IFN-gamma production. J Immunol (1993) 2.00
'B-cell factors' are pleiotropic. Immunol Today (1988) 1.94
Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets. Science (1995) 1.90
Heterogeneity of single cell cytokine gene expression in clonal T cell populations. J Exp Med (1994) 1.88
GATA-3-dependent enhancer activity in IL-4 gene regulation. J Immunol (1998) 1.81
Pathogen-induced Th1 phenotype development in CD4+ alpha beta-TCR transgenic T cells is macrophage dependent. Int Immunol (1993) 1.80
One-megabase sequence analysis of the human immunoglobulin lambda gene locus. Genome Res (1997) 1.77
Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice. J Immunol Methods (1993) 1.70
Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis. Arthritis Rheum (1998) 1.69
Molecular diagnosis and epidemiology of fungal infections. Med Mycol (1998) 1.64
Th1 and Th2 cytokine induction in pulmonary T cells during infection with respiratory syncytial virus. J Gen Virol (1996) 1.59
Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc Natl Acad Sci U S A (1996) 1.59
Enhancement of T cell-independent immune responses in vivo by CD40 antibodies. Nat Med (1998) 1.54
A unitary mechanism of calcium antagonist drug action. Proc Natl Acad Sci U S A (1983) 1.53
Interleukin 4 (B-cell growth factor II/eosinophil differentiation factor) is a mitogen and differentiation factor for preactivated murine B lymphocytes. Proc Natl Acad Sci U S A (1986) 1.53
Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells. J Exp Med (1999) 1.52
Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development. Proc Natl Acad Sci U S A (1995) 1.51
TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression. Eur J Immunol (2000) 1.48
A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production. J Exp Med (2001) 1.48
GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels. Clin Immunol (1999) 1.46
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J Immunol (1996) 1.45
Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. Mol Cell Biol (2001) 1.43
Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells. J Immunol (1998) 1.43
Calcium antagonist receptor binding sites labeled with [3H]nitrendipine. Eur J Pharmacol (1982) 1.41
Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1. Blood (1999) 1.41
IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol (1998) 1.38
Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent. J Immunol (1993) 1.38
T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development. J Immunol (1997) 1.37
Technique for securing guide wires in cannulated screw systems. Am J Orthop (Belle Mead NJ) (1996) 1.37
[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists. Proc Natl Acad Sci U S A (1982) 1.37
Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol (1999) 1.35
Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells. J Immunol (1999) 1.35
Structure and specificity of GATA proteins in Th2 development. Mol Cell Biol (2001) 1.34