Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics.

PubWeight™: 2.69‹?› | Rank: Top 1%

🔗 View Article (PMID 9791177)

Published in Mol Microbiol on October 01, 1998

Authors

H Brötz1, M Josten, I Wiedemann, U Schneider, F Götz, G Bierbaum, H G Sahl

Author Affiliations

1: Institut für Medizinische Mikrobiologie und Immunologie der Universität Bonn, D-53105 Bonn, Germany.

Articles citing this

Transcriptional profiling reveals that daptomycin induces the Staphylococcus aureus cell wall stress stimulon and genes responsive to membrane depolarization. Antimicrob Agents Chemother (2007) 2.27

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A (2006) 2.19

Biosynthesis of the lantibiotic mersacidin: organization of a type B lantibiotic gene cluster. Appl Environ Microbiol (2000) 1.81

Katanosin B and plusbacin A(3), inhibitors of peptidoglycan synthesis in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2001) 1.57

Lantibiotics from Geobacillus thermodenitrificans. Proc Natl Acad Sci U S A (2012) 1.53

Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci. Infect Immun (2010) 1.48

Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation. Appl Environ Microbiol (2007) 1.46

Cloning and engineering of the cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus cinnamoneus DSM 40005. Proc Natl Acad Sci U S A (2003) 1.44

Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance. BMC Genomics (2009) 1.39

The lipopeptide antibiotic Friulimicin B inhibits cell wall biosynthesis through complex formation with bactoprenol phosphate. Antimicrob Agents Chemother (2009) 1.38

Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies. Antimicrob Agents Chemother (2006) 1.36

Insights into the mode of action of the two-peptide lantibiotic haloduracin. ACS Chem Biol (2009) 1.32

A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii). Proc Natl Acad Sci U S A (2000) 1.30

Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations. Antimicrob Agents Chemother (2005) 1.30

Lantibiotics as probes for phosphatidylethanolamine. Amino Acids (2009) 1.20

Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance. Antimicrob Agents Chemother (2006) 1.19

Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge. Antimicrob Agents Chemother (2006) 1.18

Lipid II-mediated pore formation by the peptide antibiotic nisin: a black lipid membrane study. J Bacteriol (2004) 1.17

Novel mechanism for nisin resistance via proteolytic degradation of nisin by the nisin resistance protein NSR. Antimicrob Agents Chemother (2009) 1.17

Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate. EMBO J (2000) 1.15

Biosynthesis of the antimicrobial peptide epilancin 15X and its N-terminal lactate. Chem Biol (2011) 1.10

The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. Antimicrob Agents Chemother (2010) 1.09

Role of the single regulator MrsR1 and the two-component system MrsR2/K2 in the regulation of mersacidin production and immunity. Appl Environ Microbiol (2002) 1.07

Membrane interaction of the glycosyltransferase MurG: a special role for cardiolipin. J Bacteriol (2003) 1.06

Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus. PLoS Pathog (2012) 1.06

Mechanism of inhibition of Bacillus anthracis spore outgrowth by the lantibiotic nisin. ACS Chem Biol (2011) 1.06

TelA contributes to the innate resistance of Listeria monocytogenes to nisin and other cell wall-acting antibiotics. Antimicrob Agents Chemother (2010) 1.05

Mechanisms of resistance to bacteriocins targeting the mannose phosphotransferase system. Appl Environ Microbiol (2011) 1.04

Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic. Antimicrob Agents Chemother (2007) 1.02

Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes. J Bacteriol (2006) 1.02

Molecular analysis of expression of the lantibiotic pep5 immunity phenotype. Appl Environ Microbiol (1999) 1.02

Lipid II-based antimicrobial activity of the lantibiotic plantaricin C. Appl Environ Microbiol (2006) 1.01

Entianin, a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity. Appl Environ Microbiol (2011) 0.98

Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation. Proc Natl Acad Sci U S A (2002) 0.98

Activity of gallidermin on Staphylococcus aureus and Staphylococcus epidermidis biofilms. Antimicrob Agents Chemother (2012) 0.96

Substrate recognition and specificity of the NisB protein, the lantibiotic dehydratase involved in nisin biosynthesis. J Biol Chem (2011) 0.96

Specific interaction of the unmodified bacteriocin Lactococcin 972 with the cell wall precursor lipid II. Appl Environ Microbiol (2008) 0.96

Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics. Curr Opin Microbiol (2008) 0.95

Bioengineering of a Nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants Nisin F, Q and Z. Microb Biotechnol (2010) 0.95

Alanine scan of [L-Dap(2)]ramoplanin A2 aglycon: assessment of the importance of each residue. J Am Chem Soc (2007) 0.95

The maltose ABC transporter in Lactococcus lactis facilitates high-level sensitivity to the circular bacteriocin garvicin ML. Antimicrob Agents Chemother (2012) 0.95

Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry. J Am Chem Soc (2011) 0.94

Lysine-oriented charges trigger the membrane binding and activity of nukacin ISK-1. Appl Environ Microbiol (2006) 0.93

Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus. Antimicrob Agents Chemother (2009) 0.92

Role of lipid II and membrane thickness in the mechanism of action of the lantibiotic bovicin HC5. Antimicrob Agents Chemother (2011) 0.91

Mechanism of action and limited cross-resistance of new lipopeptide MX-2401. Antimicrob Agents Chemother (2011) 0.90

Lantibiotic resistance. Microbiol Mol Biol Rev (2015) 0.89

Membrane lipids determine the antibiotic activity of the lantibiotic gallidermin. J Membr Biol (2008) 0.89

The lantibiotic NAI-107 binds to bactoprenol-bound cell wall precursors and impairs membrane functions. J Biol Chem (2014) 0.89

Nukacin ISK-1, a bacteriostatic lantibiotic. Antimicrob Agents Chemother (2009) 0.89

Characterization of a regulatory network of peptide antibiotic detoxification modules in Lactobacillus casei BL23. Appl Environ Microbiol (2013) 0.88

Circumventing the effect of product toxicity: development of a novel two-stage production process for the lantibiotic gallidermin. Appl Environ Microbiol (2006) 0.87

Purification, characterization, and gene sequence of michiganin A, an actagardine-like lantibiotic produced by the tomato pathogen Clavibacter michiganensis subsp. michiganensis. Appl Environ Microbiol (2006) 0.87

Overproduction of wild-type and bioengineered derivatives of the lantibiotic lacticin 3147. Appl Environ Microbiol (2006) 0.87

Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147. Microb Biotechnol (2009) 0.86

Evaluation of a nisin-eluting nanofiber scaffold to treat Staphylococcus aureus-induced skin infections in mice. Antimicrob Agents Chemother (2013) 0.86

Cell wall antibiotics provoke accumulation of anchored mCherry in the cross wall of Staphylococcus aureus. PLoS One (2012) 0.85

Intensive mutagenesis of the nisin hinge leads to the rational design of enhanced derivatives. PLoS One (2013) 0.85

Novel LanT associated lantibiotic clusters identified by genome database mining. PLoS One (2014) 0.85

Relatedness between the two-component lantibiotics lacticin 3147 and staphylococcin C55 based on structure, genetics and biological activity. BMC Microbiol (2007) 0.84

Isolation of a variant of subtilosin A with hemolytic activity. J Bacteriol (2009) 0.84

In vivo pharmacokinetics and pharmacodynamics of the lantibiotic NAI-107 in a neutropenic murine thigh infection model. Antimicrob Agents Chemother (2014) 0.84

Chemical synthesis and biological activity of analogues of the lantibiotic epilancin 15X. J Am Chem Soc (2012) 0.84

The Lcn972 bacteriocin-encoding plasmid pBL1 impairs cellobiose metabolism in Lactococcus lactis. Appl Environ Microbiol (2011) 0.83

Antibacterial activities of nisin Z encapsulated in liposomes or produced in situ by mixed culture during cheddar cheese ripening. Appl Environ Microbiol (2002) 0.83

Assessing the contributions of the LiaS histidine kinase to the innate resistance of Listeria monocytogenes to nisin, cephalosporins, and disinfectants. Appl Environ Microbiol (2012) 0.83

The bacterial peptide pheromone plantaricin A permeabilizes cancerous, but not normal, rat pituitary cells and differentiates between the outer and inner membrane leaflet. J Membr Biol (2007) 0.82

The First structure of a lantibiotic immunity protein, SpaI from Bacillus subtilis, reveals a novel fold. J Biol Chem (2012) 0.82

Cyclic lipodepsipeptides: a new class of antibacterial agents in the battle against resistant bacteria. Future Med Chem (2013) 0.82

Bacterial strategies of resistance to antimicrobial peptides. Philos Trans R Soc Lond B Biol Sci (2016) 0.82

Intracellular vesicles as reproduction elements in cell wall-deficient L-form bacteria. PLoS One (2012) 0.82

Generation of ramoplanin-resistant Staphylococcus aureus. FEMS Microbiol Lett (2010) 0.82

Lantibiotic immunity: inhibition of nisin mediated pore formation by NisI. PLoS One (2014) 0.81

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus. Antimicrob Agents Chemother (2014) 0.80

Influence of Ca(2+) ions on the activity of lantibiotics containing a mersacidin-like lipid II binding motif. Appl Environ Microbiol (2009) 0.80

Structural variations of the cell wall precursor lipid II and their influence on binding and activity of the lipoglycopeptide antibiotic oritavancin. Antimicrob Agents Chemother (2014) 0.80

Structure and mechanism of lanthipeptide biosynthetic enzymes. Curr Opin Struct Biol (2014) 0.79

The putative lactococcal extracytoplasmic function anti-sigma factor llmg2447 determines resistance to the cell wall-active bacteriocin lcn972. Antimicrob Agents Chemother (2012) 0.79

Mode of action and structure-activity relationship studies of geobacillin I. J Antibiot (Tokyo) (2013) 0.79

The C-terminus of nisin is important for the ABC transporter NisFEG to confer immunity in Lactococcus lactis. Microbiologyopen (2014) 0.79

Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides. Front Cell Dev Biol (2016) 0.78

Specific interactions of clausin, a new lantibiotic, with lipid precursors of the bacterial cell wall. Biophys J (2009) 0.78

Antimicrobial Peptides Targeting Gram-Positive Bacteria. Pharmaceuticals (Basel) (2016) 0.77

Lethal hydroxyl radical accumulation by a lactococcal bacteriocin, lacticin Q. Antimicrob Agents Chemother (2013) 0.77

Synthesis and succinylation of subtilin-like lantibiotics are strongly influenced by glucose and transition state regulator AbrB. Appl Environ Microbiol (2014) 0.77

Activation of Histidine Kinase SpaK Is Mediated by the N-Terminal Portion of Subtilin-Like Lantibiotics and Is Independent of Lipid II. Appl Environ Microbiol (2015) 0.77

In vivo cluster formation of nisin and lipid II is correlated with membrane depolarization. Antimicrob Agents Chemother (2015) 0.77

Envelope Structures of Gram-Positive Bacteria. Curr Top Microbiol Immunol (2016) 0.76

The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin. J Biol Chem (2015) 0.76

Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes. Chem Rev (2017) 0.75

Docking and molecular dynamics simulations of the ternary complex nisin2:lipid II. Sci Rep (2016) 0.75

Resistance to Antimicrobial Peptides in Vibrios. Antibiotics (Basel) (2014) 0.75

Effect of nisin on biogenic amines and shelf life of vacuum packaged rainbow trout (Oncorhynchus mykiss) fillets. J Food Sci Technol (2017) 0.75

Articles by these authors

TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell (1996) 8.03

The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infect Immun (1999) 7.22

Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol Microbiol (1996) 7.16

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell (1993) 6.44

Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J Biol Chem (1999) 6.44

Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface. Mol Microbiol (1997) 5.47

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic. Science (1999) 5.30

Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int J Cancer (1977) 4.53

Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings. Nature (1988) 4.41

Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection. Blood (1997) 4.36

Impact of the agr quorum-sensing system on adherence to polystyrene in Staphylococcus aureus. J Infect Dis (2000) 4.19

Characterization of Tn917 insertion mutants of Staphylococcus epidermidis affected in biofilm formation. Infect Immun (1996) 3.95

Occurrence of Epstein-Barr virus genomes in human lymphoblastoid cell lines. Nat New Biol (1972) 3.84

Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles. Antimicrob Agents Chemother (1985) 3.83

Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin. J Biol Chem (1998) 3.80

Detection of the intercellular adhesion gene cluster (ica) and phase variation in Staphylococcus epidermidis blood culture strains and mucosal isolates. Infect Immun (1997) 3.71

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity. J Biol Chem (2000) 3.65

Genetic analysis of epidermin biosynthetic genes and epidermin-negative mutants of Staphylococcus epidermidis. Eur J Biochem (1992) 3.54

A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256. Mol Microbiol (1999) 3.48

Transformation of Staphylococcus epidermidis and other staphylococcal species with plasmid DNA by electroporation. FEMS Microbiol Lett (1990) 3.45

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates. J Clin Microbiol (2009) 3.45

A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J Bacteriol (1997) 3.25

Lantibiotics: biosynthesis and biological activities of uniquely modified peptides from gram-positive bacteria. Annu Rev Microbiol (1998) 3.04

Key role of teichoic acid net charge in Staphylococcus aureus colonization of artificial surfaces. Infect Immun (2001) 2.96

Anaerobic conditions induce expression of polysaccharide intercellular adhesin in Staphylococcus aureus and Staphylococcus epidermidis. Infect Immun (2001) 2.72

The D-alanine residues of Staphylococcus aureus teichoic acids alter the susceptibility to vancomycin and the activity of autolytic enzymes. Antimicrob Agents Chemother (2000) 2.71

Reproduction of transfusion-related acute lung injury in an ex vivo lung model. Blood (1990) 2.54

Biosynthesis and biological activities of lantibiotics with unique post-translational modifications. Eur J Biochem (1995) 2.37

Gallidermin: a new lanthionine-containing polypeptide antibiotic. Eur J Biochem (1988) 2.32

Production, purification and chemical properties of an antistaphylococcal agent produced by Staphylococcus epidermidis. J Gen Microbiol (1981) 2.20

Inhibition of virulence factor expression in Staphylococcus aureus by the Staphylococcus epidermidis agr pheromone and derivatives. FEBS Lett (1999) 2.16

Mode of action of the staphylococcinlike peptide Pep 5: voltage-dependent depolarization of bacterial and artificial membranes. J Bacteriol (1988) 2.10

Mechanistic studies of lantibiotic-induced permeabilization of phospholipid vesicles. Biochemistry (1995) 2.10

Characterization of the importance of Staphylococcus epidermidis autolysin and polysaccharide intercellular adhesin in the pathogenesis of intravascular catheter-associated infection in a rat model. J Infect Dis (2001) 2.10

Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus. J Bacteriol (1994) 2.07

Laparoscopic appendectomy in 625 cases: from innovation to routine. Surg Laparosc Endosc (1991) 2.07

Expression and regulation of the antimonite, arsenite, and arsenate resistance operon of Staphylococcus xylosus plasmid pSX267. J Bacteriol (1992) 2.06

The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II. Antimicrob Agents Chemother (1998) 2.06

Geographical prevalence of two types of Epstein-Barr virus. Virology (1986) 2.05

Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic. Eur J Biochem (1986) 2.04

Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett (1998) 1.96

Interaction of the pore forming-peptide antibiotics Pep 5, nisin and subtilin with non-energized liposomes. FEBS Lett (1989) 1.95

Analysis of genes involved in the biosynthesis of lantibiotic epidermin. Eur J Biochem (1992) 1.94

Presence of Staphylococcus aureus with reduced susceptibility to vancomycin in Germany. Eur J Clin Microbiol Infect Dis (1999) 1.87

Pep5, a new lantibiotic: structural gene isolation and prepeptide sequence. Arch Microbiol (1989) 1.85

Autolytic system of Staphylococcus simulans 22: influence of cationic peptides on activity of N-acetylmuramoyl-L-alanine amidase. J Bacteriol (1987) 1.82

Inducible production and cellular location of the epidermin biosynthetic enzyme EpiB using an improved staphylococcal expression system. FEMS Microbiol Lett (1996) 1.81

Biosynthesis of the lantibiotic mersacidin: organization of a type B lantibiotic gene cluster. Appl Environ Microbiol (2000) 1.81

Induction of autolysis of staphylococci by the basic peptide antibiotics Pep 5 and nisin and their influence on the activity of autolytic enzymes. Arch Microbiol (1985) 1.81

Staphylocidal action of thrombin-induced platelet microbicidal protein is not solely dependent on transmembrane potential. Infect Immun (1996) 1.79

HEAT repeats mediate plasma membrane localization of Tor2p in yeast. J Biol Chem (2000) 1.75

The 200-MeV proton therapy project at the Paul Scherrer Institute: conceptual design and practical realization. Med Phys (1995) 1.75

Reactive knee and ankle joint arthritis: abnormal manifestation of Legionella pneumophila. Rheumatol Int (2003) 1.74

Structural analysis and proteolytic activation of Enterococcus faecalis cytolysin, a novel lantibiotic. Mol Microbiol (1996) 1.71

Influence of the staphylococcinlike peptide Pep 5 on membrane potential of bacterial cells and cytoplasmic membrane vesicles. J Bacteriol (1985) 1.71

Oxygen utilization by Lactobacillus plantarum. I. Oxygen consuming reactions. Arch Microbiol (1980) 1.71

Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis. Br J Surg (2006) 1.71

Plasmid transfer and genetic recombination by protoplast fusion in staphylococci. J Bacteriol (1981) 1.70

Purification and biochemical characterization of pyruvate oxidase from Lactobacillus plantarum. J Bacteriol (1984) 1.64

Expression of the gene encoding protein A in Staphylococcus aureus and coagulase-negative staphylococci. J Bacteriol (1984) 1.61

Comparative analysis of a biofilm-forming Staphylococcus epidermidis strain and its adhesion-positive, accumulation-negative mutant M7. FEMS Microbiol Lett (1994) 1.60

Pheromone cross-inhibition between Staphylococcus aureus and Staphylococcus epidermidis. Infect Immun (2001) 1.59

The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation. Eur J Biochem (1997) 1.59

Mode of action of the staphylococcin-like peptide Pep 5 and culture conditions effecting its activity. Zentralbl Bakteriol Mikrobiol Hyg A (1982) 1.58

DNA homology between the arsenate resistance plasmid pSX267 from Staphylococcus xylosus and the penicillinase plasmid pI258 from Staphylococcus aureus. Plasmid (1983) 1.56

Retinal choroidal anastomoses and occult choroidal neovascularization in age-related macular degeneration. Ophthalmology (2000) 1.55

The peptide antibiotic subtilin acts by formation of voltage-dependent multi-state pores in bacterial and artificial membranes. Eur J Biochem (1989) 1.54

Protein engineering of lantibiotics. Antonie Van Leeuwenhoek (1996) 1.54

Studies on prolysostaphin processing and characterization of the lysostaphin immunity factor (Lif) of Staphylococcus simulans biovar staphylolyticus. Mol Microbiol (1997) 1.54

Structural gene isolation and prepeptide sequence of gallidermin, a new lanthionine containing antibiotic. FEMS Microbiol Lett (1989) 1.53

Mode of action of the lantibiotic mersacidin: inhibition of peptidoglycan biosynthesis via a novel mechanism? Antimicrob Agents Chemother (1995) 1.52

Retinal pigment epithelial tear after photodynamic therapy for choroidal neovascularization. Am J Ophthalmol (2001) 1.51

Cell entry by measles virus: long hybrid receptors uncouple binding from membrane fusion. J Virol (1996) 1.51

Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation. Eur J Biochem (1995) 1.50

First spinal axis segment irradiation with spot-scanning proton beam delivered in the treatment of a lumbar primitive neuroectodermal tumour. Case report and review of the literature. Clin Oncol (R Coll Radiol) (2004) 1.49

Structural similarities of the staphylococcin-like peptide Pep-5 to the peptide antibiotic nisin. Antimicrob Agents Chemother (1985) 1.48

A promoter-screening plasmid and xylose-inducible, glucose-repressible expression vectors for Staphylococcus carnosus. Gene (1995) 1.48

The molecular organization of the lysostaphin gene and its sequences repeated in tandem. Mol Gen Genet (1987) 1.47

Analysis of the Staphylococcus epidermidis genes epiF, -E, and -G involved in epidermin immunity. J Bacteriol (1996) 1.46

[Lymphatic mapping and sentinel lymph node biopsy in gastric cancer]. Chirurg (2003) 1.44

Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas. Am J Pathol (2001) 1.43

[Laparoscopic placement of T-drainage in choledocholithiasis]. Chirurg (1991) 1.43

Regulation of epidermin biosynthetic genes by EpiQ. Mol Microbiol (1993) 1.42

Staphylococcal lipases: biochemical and molecular characterization. Biochimie (2000) 1.42

Negative absolute temperature for motional degrees of freedom. Science (2013) 1.41

Organization, promoter analysis and transcriptional regulation of the Staphylococcus xylosus xylose utilization operon. Mol Gen Genet (1991) 1.40

Biosynthesis of the lantibiotic Pep5. Isolation and characterization of a prepeptide containing dehydroamino acids. Eur J Biochem (1990) 1.40