Published in J Neurochem on November 01, 1998
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science (2007) 4.08
Lessons from lactose permease. Annu Rev Biophys Biomol Struct (2006) 3.69
X-ray structures of LeuT in substrate-free outward-open and apo inward-open states. Nature (2012) 3.24
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6. Pflugers Arch (2003) 2.45
Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. Nat Struct Mol Biol (2010) 2.20
The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. J Biol Chem (2003) 2.14
Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells. Bone (2006) 1.39
Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter. J Biol Chem (2009) 1.38
The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango. J Neurochem (2009) 1.36
Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent. Neuropharmacology (2007) 1.33
Permeation and gating residues in serotonin transporter. Proc Natl Acad Sci U S A (2000) 1.30
Beta-alanine and taurine as endogenous agonists at glycine receptors in rat hippocampus in vitro. J Physiol (2002) 1.29
Trace amine-associated receptor 1 as a monoaminergic modulator in brain. Biochem Pharmacol (2009) 1.27
Structure and function of sodium-coupled GABA and glutamate transporters. J Membr Biol (2007) 1.23
Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue. PLoS Comput Biol (2010) 1.20
S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis. Br J Pharmacol (2012) 1.19
The solute carrier 6 family of transporters. Br J Pharmacol (2012) 1.14
Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem (2010) 1.08
The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2). Biochem J (2006) 1.08
Role of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuse. CNS Neurol Disord Drug Targets (2008) 1.03
Gamma-Aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers. Br J Pharmacol (2000) 1.03
GABA and central neuropathic pain following spinal cord injury. Neuropharmacology (2011) 1.02
The glycine neurotransmitter transporter GLYT1 is an organic osmolyte transporter regulating cell volume in cleavage-stage embryos. Proc Natl Acad Sci U S A (2003) 1.02
Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate. Proc Natl Acad Sci U S A (2013) 0.99
Functional consequences of homo- but not hetero-oligomerization between transporters for the biogenic amine neurotransmitters. J Neurochem (2003) 0.98
Plasmalemmal and vesicular gamma-aminobutyric acid transporter expression in the developing mouse retina. J Comp Neurol (2009) 0.97
Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes. Front Endocrinol (Lausanne) (2013) 0.96
Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies. J Mol Biol (2008) 0.95
Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. Eur J Neurosci (2009) 0.92
Transmembrane domain 8 of the {gamma}-aminobutyric acid transporter GAT-1 lines a cytoplasmic accessibility pathway into its binding pocket. J Biol Chem (2009) 0.92
Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytes. Proc Natl Acad Sci U S A (2001) 0.92
A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1. J Biol Chem (2010) 0.91
Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Mol Cell Biol (2004) 0.89
Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4). J Membr Biol (2005) 0.88
Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships. Cell Mol Neurobiol (2004) 0.87
4-(4-(dimethylamino)phenyl)-1-methylpyridinium (APP+) is a fluorescent substrate for the human serotonin transporter. J Biol Chem (2012) 0.87
SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission. J Biol Chem (2009) 0.87
An acidic amino acid transmembrane helix 10 residue conserved in the neurotransmitter:sodium:symporters is essential for the formation of the extracellular gate of the γ-aminobutyric acid (GABA) transporter GAT-1. J Biol Chem (2012) 0.86
Structure, function, and plasticity of GABA transporters. Front Cell Neurosci (2014) 0.86
Turnover rate of the gamma-aminobutyric acid transporter GAT1. J Membr Biol (2007) 0.86
Partial regulation of serotonin transporter function by gamma-synuclein. Neurosci Lett (2009) 0.84
Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport. J Biol Chem (2009) 0.83
Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine. PET Clin (2009) 0.82
N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo. Mol Cell Neurosci (2014) 0.81
Discovery of novel selective serotonin reuptake inhibitors through development of a protein-based pharmacophore. J Chem Inf Model (2011) 0.81
Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1. Br J Pharmacol (2002) 0.81
Zinc inhibition of gamma-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission. Proc Natl Acad Sci U S A (2005) 0.81
Biophysical Approaches to the Study of LeuT, a Prokaryotic Homolog of Neurotransmitter Sodium Symporters. Methods Enzymol (2015) 0.80
Functional defects in the external and internal thin gates of the γ-aminobutyric acid (GABA) transporter GAT-1 can compensate each other. J Biol Chem (2013) 0.80
Ethanol potentiates dopamine uptake and increases cell surface distribution of dopamine transporters expressed in SK-N-SH and HEK-293 cells. Alcohol (2008) 0.80
GATMD: γ-aminobutyric acid transporter mutagenesis database. Database (Oxford) (2010) 0.78
Transcriptome-wide identification of preferentially expressed genes in the hypothalamus and pituitary gland. Front Endocrinol (Lausanne) (2012) 0.78
Ethanol alters endosomal recycling of human dopamine transporters. J Biol Chem (2010) 0.78
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na+ symporter family. BMC Bioinformatics (2007) 0.77
Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. J Membr Biol (2012) 0.77
Inhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction. Neurochem Int (2009) 0.77
A putative amino acid transporter of the solute carrier 6 family is upregulated by lithium and is required for resistance to lithium toxicity in Drosophila. Neuroscience (2009) 0.77
Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis. J Biol Chem (2014) 0.77
Cynomorium songaricum extract enhances novel object recognition, cell proliferation and neuroblast differentiation in the mice via improving hippocampal environment. BMC Complement Altern Med (2014) 0.76
The aromatic and charge pairs of the thin extracellular gate of the γ-aminobutyric acid transporter GAT-1 are differently impacted by mutation. J Biol Chem (2014) 0.76
Norepinephrine transporter heterozygous knockout mice exhibit altered transport and behavior. Genes Brain Behav (2013) 0.76
N-Ethylmaleimide differentially inhibits substrate uptake by and ligand binding to the noradrenaline transporter. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.75
Genome-Wide Identification, Characterization and Expression Analysis of the Solute Carrier 6 Gene Family in Silkworm (Bombyx mori). Int J Mol Sci (2016) 0.75
An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport. J Biol Chem (2017) 0.75
The effects of volatile anesthetics on the extracellular accumulation of [(3)H]GABA in rat brain cortical slices. Cell Mol Neurobiol (2013) 0.75
Cloning of genes or cDNAs encoding neurotransmitter transporters and their localization by immunocytochemistry. Methods Enzymol (1998) 0.75