Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.

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Published in EMBO J on November 02, 1998

Authors

X Zhang1, S Moréra, P A Bates, P C Whitehead, A I Coffer, K Hainbucher, R A Nash, M J Sternberg, T Lindahl, P S Freemont

Author Affiliations

1: Molecular Structure and Function, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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Oligomeric ring structure of the Bloom's syndrome helicase. Curr Biol (1999) 2.01

Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli. Nucleic Acids Res (1985) 2.00

Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc Natl Acad Sci U S A (1997) 1.89

Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution. Biochemistry (1973) 1.88