Published in Clin Cancer Res on November 01, 1995
Regulation of human immunodeficiency virus replication by 2',5'-oligoadenylate-dependent RNase L. J Virol (1998) 1.02
Regulation of human RNase-L by the miR-29 family reveals a novel oncogenic role in chronic myelogenous leukemia. J Interferon Cytokine Res (2012) 0.87
Pathologic effects of RNase-L dysregulation in immunity and proliferative control. Front Biosci (Schol Ed) (2012) 0.83
RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer. Inflamm Bowel Dis (2013) 0.82
Curcumin, a natural antioxidant, acts as a noncompetitive inhibitor of human RNase L in presence of its cofactor 2-5A in vitro. Biomed Res Int (2014) 0.77
How cells respond to interferons. Annu Rev Biochem (1998) 24.27
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci U S A (1998) 13.39
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell (1995) 9.11
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell (1990) 7.12
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase. EMBO J (1995) 6.94
Tat trans-activates the human immunodeficiency virus through a nascent RNA target. Cell (1989) 6.28
Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol (2001) 6.19
Methicillin-resistant Staphylococcus aureus in U.S. hospitals, 1975-1991. Infect Control Hosp Epidemiol (1992) 5.98
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature (1997) 5.35
Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization. N Engl J Med (2001) 5.29
Fecal Incontinence Quality of Life Scale: quality of life instrument for patients with fecal incontinence. Dis Colon Rectum (2000) 5.07
Structure, expression, and evolution of a gene encoding the precursor of nisin, a small protein antibiotic. J Biol Chem (1988) 4.68
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc Natl Acad Sci U S A (1994) 4.53
Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L. EMBO J (1997) 4.53
ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins. Nucleic Acids Res (2001) 4.47
A prospective study of endogenous estrogens and breast cancer in postmenopausal women. J Natl Cancer Inst (1995) 4.29
Patient and surgeon ranking of the severity of symptoms associated with fecal incontinence: the fecal incontinence severity index. Dis Colon Rectum (1999) 4.20
Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action. Cell (1993) 4.10
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc Natl Acad Sci U S A (1997) 3.88
Ileal pouch-anal anastomoses complications and function in 1005 patients. Ann Surg (1995) 3.85
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis (2003) 3.73
Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2. EMBO J (1992) 3.65
Inhibition of cell-free protein synthesis by pppA2'p5'A2'p5'A: a novel oligonucleotide synthesized by interferon-treated L cell extracts. Cell (1978) 3.53
Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proc Natl Acad Sci U S A (2000) 3.51
Prospective controlled study of psychiatric out-patient non-attendance. Characteristics and outcome. Br J Psychiatry (2000) 3.49
Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways. Virology (1999) 3.44
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO J (1997) 3.34
Factors associated with the occurrence of leaks in stapled rectal anastomoses: a review of 1,014 patients. J Am Coll Surg (1997) 3.30
Nosocomial infection rates in adult and pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System. Am J Med (1991) 3.06
National nosocomial infections surveillance system (NNIS): description of surveillance methods. Am J Infect Control (1991) 3.00
Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis. Mol Cell Biol (2001) 2.85
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity (2000) 2.81
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J Biol Chem (1998) 2.75
NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase. Mol Cell Biol (2000) 2.71
Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation. EMBO J (1998) 2.68
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene. EMBO J (1988) 2.66
Collagen fibril formation. Optimal in vitro conditions and preliminary kinetic results. J Biol Chem (1978) 2.65
The prevalence of Tourette syndrome in a mainstream school population. Dev Med Child Neurol (1998) 2.56
Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system. Mol Cell Biol (1991) 2.55
Botulism from chopped garlic: delayed recognition of a major outbreak. Ann Intern Med (1988) 2.47
Accuracy of the E test for determining antimicrobial susceptibilities of staphylococci, enterococci, Campylobacter jejuni, and gram-negative bacteria resistant to antimicrobial agents. J Clin Microbiol (1992) 2.45
Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2'p)nA) in interferon-treated cells. Nucleic Acids Res (1981) 2.42
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc Natl Acad Sci U S A (1997) 2.42
Arc-scanning very high-frequency digital ultrasound for 3D pachymetric mapping of the corneal epithelium and stroma in laser in situ keratomileusis. J Refract Surg (2000) 2.40
EUROCARE: a cross-national study of co-resident spouse carers for people with Alzheimer's disease: I--Factors associated with carer burden. Int J Geriatr Psychiatry (1999) 2.36
A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J (1993) 2.28
2-5A-dependent RNase molecules dimerize during activation by 2-5A. J Biol Chem (1995) 2.27
Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase. Proc Natl Acad Sci U S A (1992) 2.20
The Glasgow Dyspepsia Severity Score--a tool for the global measurement of dyspepsia. Eur J Gastroenterol Hepatol (1996) 2.19
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. EMBO J (2000) 2.11
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. EMBO J (1999) 2.07
Women in UK cardiology: report of a Working Group of the British Cardiac Society. Heart (2005) 2.06
Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res (1998) 2.04
Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells. Nature (1980) 2.03
Continuous infusion of local anaesthetic following laparoscopic hysterectomy--a randomised controlled trial. BJOG (2014) 2.02
Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells. Nature (1979) 2.01
Results from an American Society of Colon and Rectal Surgeons survey on the management of young-onset colorectal cancer. Tech Coloproctol (2013) 2.01
The cloning of two Arabidopsis genes belonging to a phosphate transporter family. Plant J (1997) 2.01
Neostigmine: safe and effective treatment for acute colonic pseudo-obstruction. Dis Colon Rectum (2000) 1.99
Effects of baclofen on the functional anatomy of the oesophago-gastric junction and proximal stomach in healthy volunteers and patients with GERD assessed by magnetic resonance imaging and high-resolution manometry: a randomised controlled double-blind study. Aliment Pharmacol Ther (2014) 1.99
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin. EMBO J (2000) 1.98
A precision measurement of the mass of the top quark. Nature (2004) 1.87
Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways. Mol Cell Biol (2000) 1.83
Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology. Health Technol Assess (2005) 1.83
Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest (1998) 1.82
Gravidity-dependent production of antibodies that inhibit binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate proteoglycan during pregnancy. Infect Immun (2001) 1.82
rRNA cleavage as an index of ppp(A2'p)nA activity in interferon-treated encephalomyocarditis virus-infected cells. J Virol (1983) 1.81
Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA. J Biol Chem (1997) 1.77
Collagen fibril formation. Evidence for a multistep process. J Biol Chem (1979) 1.77
Non-attendance at psychiatric outpatient clinics: communication and implications for primary care. Br J Gen Pract (1999) 1.76
Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits. Circ Res (1999) 1.75
Epidemiology and mortality risk of vancomycin-resistant enterococcal bloodstream infections. J Infect Dis (1995) 1.75
Our approach to the management of congenital presacral tumors in adults. Int J Colorectal Dis (1993) 1.74
Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase in Escherichia coli. Genetics (1972) 1.73
Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras. Science (1994) 1.72
A mutation increasing the amount of a constitutive enzyme in Escherichia coli, glucose 6-phosphate dehydrogenase. J Mol Biol (1971) 1.72
Prevalence of depressive symptoms and syndromes in later life in ten European countries: the SHARE study. Br J Psychiatry (2007) 1.72
Early immune response in healthy and immunocompromised subjects with primary varicella-zoster virus infection. J Infect Dis (1986) 1.72
Macular hole surgery with silicone oil. Eye (Lond) (2002) 1.71
The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. Proc Natl Acad Sci U S A (1995) 1.70
Act1, an NF-kappa B-activating protein. Proc Natl Acad Sci U S A (2000) 1.70
Activation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA. Nucleic Acids Res (1989) 1.70
DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR. J Biol Chem (1999) 1.70
A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR. EMBO J (2000) 1.68