Published in J Biol Chem on December 11, 1998
Nitric oxide synthases: structure, function and inhibition. Biochem J (2001) 9.73
Role of nitric oxide synthase in the light-induced development of sporangiophores in Phycomyces blakesleeanus. Plant Physiol (2001) 0.91
Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide. Biochem J (2000) 0.90
Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity. Biochem J (1999) 0.89
Pharmacology and Clinical Drug Candidates in Redox Medicine. Antioxid Redox Signal (2015) 0.79
Pterin interactions with distinct reductase activities of NO synthase. Biochem J (2001) 0.78
Inhibition of endotoxin-induced vascular hyporeactivity by 4-amino-tetrahydrobiopterin. Br J Pharmacol (2000) 0.77
Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: studies on the nature and mechanism of tight pterin binding. Biochemistry (2014) 0.77
Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase. Antioxid Redox Signal (2015) 0.76
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 4.50
Benzophenone photophores in biochemistry. Biochemistry (1994) 4.05
Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus. J Virol (1993) 3.37
Biocompatible surfactants for water-in-fluorocarbon emulsions. Lab Chip (2008) 3.28
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 3.15
Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study. Leukemia (2008) 3.10
Correlation between structure and pathogenicity of potato spindle tuber viroid (PSTV). EMBO J (1985) 2.63
Epithelial M cells: gateways for mucosal infection and immunization. Cell (1996) 2.41
Replacement of calcineurin inhibitors with mycophenolate mofetil in liver-transplant patients with renal dysfunction: a randomised controlled study. Lancet (2001) 2.39
Fluorescence and optical characteristics of reduced flavines and flavoproteins. Biochemistry (1974) 2.37
Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase. Cell (1986) 2.34
The influence of pneumoperitoneum used in laparoscopic surgery on an intraabdominal tumor growth. Cancer (1999) 2.34
Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem Pharmacol (1991) 2.34
Reduction of the diagnostic window with a new combined p24 antigen and human immunodeficiency virus antibody screening assay. J Virol Methods (1998) 2.31
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci U S A (1996) 2.16
Conformational transitions in viroids and virusoids: comparison of results from energy minimization algorithm and from experimental data. J Biomol Struct Dyn (1984) 2.14
Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. FEBS Lett (1993) 2.14
A randomized trial comparing primary angioplasty with a strategy of short-acting thrombolysis and immediate planned rescue angioplasty in acute myocardial infarction: the PACT trial. PACT investigators. Plasminogen-activator Angioplasty Compatibility Trial. J Am Coll Cardiol (1999) 2.14
No .NO from NO synthase. Proc Natl Acad Sci U S A (1996) 2.14
Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides. J Biol Chem (1999) 2.08
Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A (1992) 1.93
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem (2001) 1.86
Molecular basis for the explanation of the exponential growth of polyelectrolyte multilayers. Proc Natl Acad Sci U S A (2002) 1.80
[Prophylaxis, diagnosis and therapy of hepatitis C virus (HCV) infection: the German guidelines on the management of HCV infection]. Z Gastroenterol (2010) 1.76
A pleckstrin homology domain specific for phosphatidylinositol 4, 5-bisphosphate (PtdIns-4,5-P2) and fused to green fluorescent protein identifies plasma membrane PtdIns-4,5-P2 as being important in exocytosis. J Biol Chem (2000) 1.76
Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase. Biochem Pharmacol (1997) 1.74
Inhibitors of arachidonoyl ethanolamide hydrolysis. J Biol Chem (1994) 1.72
Rapid accumulation of phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate correlates with calcium mobilization in salt-stressed arabidopsis. Plant Physiol (2001) 1.69
The structure of L-amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site. EMBO J (2000) 1.67
Intracellular delivery of phosphoinositides and inositol phosphates using polyamine carriers. Proc Natl Acad Sci U S A (2000) 1.66
Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi. Infect Immun (1993) 1.64
Using photolabile ligands in drug discovery and development. Trends Biotechnol (2000) 1.64
Hepatitis B virus clearance by transplantation of bone marrow from hepatitis B immunised donor. Lancet (1997) 1.63
Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. Proc Natl Acad Sci U S A (1996) 1.62
Kinetic properties of a sex pheromone-degrading enzyme: the sensillar esterase of Antheraea polyphemus. Proc Natl Acad Sci U S A (1985) 1.61
Regional distribution of EDRF/NO-synthesizing enzyme(s) in rat brain. Biochem Biophys Res Commun (1990) 1.61
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. Free Radic Biol Med (2001) 1.60
Moderate hypothermia in patients with severe head injury: cerebral and extracerebral effects. J Neurosurg (1996) 1.59
Cross-linked hyaluronic acid hydrogel films: new biomaterials for drug delivery. J Control Release (2000) 1.59
Localization of flexible sites in thread-like molecules from electron micrographs. Comparison of interstitial, basement membrane and intima collagens. J Mol Biol (1984) 1.59
A hydrophobic sequence motif common to N-hydroxylating enzymes. Trends Biochem Sci (1998) 1.57
Fluorescence properties of pteridine nucleoside analogs as monomers and incorporated into oligonucleotides. Anal Biochem (1997) 1.57
Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases. J Biol Chem (2000) 1.55
Identification of a phosphoinositide binding motif that mediates activation of mammalian and yeast phospholipase D isoenzymes. EMBO J (1999) 1.54
Odorant-binding-protein subfamilies associate with distinct classes of olfactory receptor neurons in insects. J Neurobiol (1991) 1.53
The dynamic air bubble trap reduces cerebral microembolism during cardiopulmonary bypass. J Thorac Cardiovasc Surg (2003) 1.52
vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys. J Virol (1995) 1.51
Rapid diagnosis of tick-borne encephalitis by means of enzyme linked immunosorbent assay. J Gen Virol (1979) 1.51
Selective substrates for non-neuronal monoamine transporters. Mol Pharmacol (1999) 1.47
Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity. Br J Pharmacol (1999) 1.47
The genetics of attention deficit/hyperactivity disorder in adults, a review. Mol Psychiatry (2011) 1.46
Malignant hyperphenylalaninaemia--current status (June 1977). J Inherit Metab Dis (1978) 1.45
The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3,-a] quinoxalin-1-one is a nonselective heme protein inhibitor of nitric oxide synthase and other cytochrome P-450 enzymes involved in nitric oxide donor bioactivation. Mol Pharmacol (1999) 1.42
Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains. J Biol Chem (1996) 1.41
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. Proc Natl Acad Sci U S A (2000) 1.41
Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traits. J Neural Transm (Vienna) (2003) 1.41
Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin. Mol Pharmacol (1990) 1.41
Colocalization of nitric oxide synthase and NADPH-diaphorase in the myenteric plexus of the rat gut. Neurosci Lett (1992) 1.40
Fabrication of magnetic artificial atoms. Nanotechnology (2012) 1.40
Characteristic alterations of the peritoneum after carbon dioxide pneumoperitoneum. Surg Endosc (1999) 1.40
[An increased risk of kinesitherapy in silent myocardial ischemia?]. Dtsch Med Wochenschr (1993) 1.38
Protein structure encodes the ligand binding specificity in pheromone binding proteins. Biochemistry (1995) 1.37
The role of polar and hydrophobic interactions for the molecular packing of type I collagen: a three-dimensional evaluation of the amino acid sequence. J Mol Biol (1978) 1.37
Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats. Circ Res (1999) 1.36
Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin. Neuroscience (1994) 1.36
Safety and immunogenicity of an inactivated hepatitis A candidate vaccine in healthy adult volunteers. Vaccine (1990) 1.35
The composition and function of M cell apical membranes: implications for microbial pathogenesis. Semin Immunol (1999) 1.35
Structure of a novel oligosaccharide-mycosporine-amino acid ultraviolet A/B sunscreen pigment from the terrestrial cyanobacterium Nostoc commune. J Biol Chem (1995) 1.34
Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree. Mol Psychiatry (2010) 1.33
Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. J Cell Biol (2000) 1.33
Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives. J Control Release (1998) 1.33
Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate. Bioconjug Chem (1999) 1.33
Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand. J Biol Chem (1997) 1.33
Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. J Biol Chem (1997) 1.32
PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1. Curr Biol (1999) 1.31
Transport of monoamine transmitters by the organic cation transporter type 2, OCT2. J Biol Chem (1998) 1.31
Complement activation by recombinant adenoviruses. Gene Ther (2001) 1.31
Physical activity and gestational weight gain: a meta-analysis of intervention trials. BJOG (2010) 1.29
Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain. J Biol Chem (1996) 1.28
Biochemical evidence for a novel low molecular weight 2-5A-dependent RNase L in chronic fatigue syndrome. J Interferon Cytokine Res (1997) 1.27
Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis. J Biol Chem (1998) 1.27
Fluorescently labeled neomycin as a probe of phosphatidylinositol-4, 5-bisphosphate in membranes. Biochim Biophys Acta (2000) 1.27
Where have all the T cells gone? Mechanisms of immune evasion by tumors. Immunol Today (1999) 1.26
Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials (2005) 1.26
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate. J Biol Chem (1998) 1.25
Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: isolation and characterization from rat brain. Proc Natl Acad Sci U S A (1991) 1.25
The superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells. J Virol (1997) 1.24
Epidemiological analysis of Neisseria gonorrhoeae in the Federal Republic of Germany by auxotyping and serological classification using monoclonal antibodies. Genitourin Med (1986) 1.23
Expression of an olfactory receptor in Escherichia coli: purification, reconstitution, and ligand binding. Biochemistry (1996) 1.23
The epidemiology of colorectal polyps: prevalence in New Orleans and international comparisons. Cancer (1977) 1.23
Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2. Biochem Biophys Res Commun (1992) 1.22
Functionalized derivatives of hyaluronic acid oligosaccharides: drug carriers and novel biomaterials. Bioconjug Chem (1994) 1.21
Effects of two mutations detected in medium chain acyl-CoA dehydrogenase (MCAD)-deficient patients on folding, oligomer assembly, and stability of MCAD enzyme. J Biol Chem (1995) 1.21