Published in Ann Neurol on December 01, 1998
Mitochondria: the next (neurode)generation. Neuron (2011) 3.06
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J Biol Chem (2008) 2.53
Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain Pathol (2003) 1.75
Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis. Biochim Biophys Acta (2008) 1.35
Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem (2005) 1.19
Mitochondrial DNA polymorphisms as risk factors for Parkinson's disease and Parkinson's disease dementia. Hum Genet (2004) 1.19
Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes. Hum Genomics (2010) 1.12
Exercise protects against MPTP-induced neurotoxicity in mice. Brain Res (2010) 1.05
The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics. Int J Biochem Cell Biol (2009) 1.05
Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases. Biochim Biophys Acta (2009) 1.01
Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues. Biochim Biophys Acta (2008) 1.00
Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease. J Biol Chem (2009) 0.94
Mitochondrial medicine for neurodegenerative diseases. Int J Biochem Cell Biol (2010) 0.93
Microtubule depolymerization potentiates alpha-synuclein oligomerization. Front Aging Neurosci (2010) 0.92
Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases. Curr Pharm Des (2011) 0.90
Role of mitochondrial dysfunction in hydrogen peroxide-induced apoptosis of intestinal epithelial cells. World J Gastroenterol (2003) 0.89
The aetiology of idiopathic Parkinson's disease. Mol Pathol (2001) 0.88
Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease. BMC Med Genet (2010) 0.87
Effects of hydrogen peroxide on mitochondrial gene expression of intestinal epithelial cells. World J Gastroenterol (2002) 0.87
The genetic basis of Parkinson's disease. J Neurol Neurosurg Psychiatry (2002) 0.84
Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships. Exp Neurol (2009) 0.83
Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence. Antioxid Redox Signal (2011) 0.83
Cytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathies. Redox Biol (2014) 0.82
Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice. PLoS One (2012) 0.82
Female genetic distribution bias in mitochondrial genome observed in Parkinson's Disease patients in northern China. Sci Rep (2015) 0.80
Mitochondrial DNA polymorphisms and the risk of Parkinson's disease in Taiwan. J Neural Transm (Vienna) (2007) 0.79
The two-century journey of Parkinson disease research. Nat Rev Neurosci (2017) 0.75
Melatonin as a mitochondrial protector in neurodegenerative diseases. Cell Mol Life Sci (2017) 0.75
Interrater reliability of the NIH stroke scale. Arch Neurol (1989) 3.52
Neuroleptic malignant syndrome: a pathogenetic role for dopamine receptor blockade? Neurology (1981) 3.47
Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA. J Biol Chem (1989) 3.19
Prevalence of HIV infection among intravenous drug users in the United States. JAMA (1989) 3.13
A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography. Ann Neurol (1984) 3.11
Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol (1989) 3.11
Cybrids in Alzheimer's disease: a cellular model of the disease? Neurology (1997) 2.85
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology (2003) 2.65
Are men at greater risk for Parkinson's disease than women? J Neurol Neurosurg Psychiatry (2004) 2.47
Phrenic nerve conduction in man. J Neurol Neurosurg Psychiatry (1967) 2.44
An experimental study of hiccup. Brain (1970) 2.43
Chemical characterization of the selenoprotein component of clostridial glycine reductase: identification of selenocysteine as the organoselenium moiety. Proc Natl Acad Sci U S A (1976) 2.43
Outpatient surgical treatment of cervical radiculopathy. J Neurosurg (1997) 2.34
The proprioceptive reflex control of the intercostal muscles during their voluntary activation. J Physiol (1970) 2.32
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene (1995) 2.26
Origin and functional consequences of the complex I defect in Parkinson's disease. Ann Neurol (1996) 2.22
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology (2008) 2.16
Enzymic procedures for determining the average state of adenylylation of Escherichia coli glutamine synthetase. Anal Biochem (1979) 1.99
Pulmonary mechanics in patients with respiratory muscle weakness. Am Rev Respir Dis (1977) 1.98
Cytochrome oxidase deficiency in Alzheimer's disease. Neurology (1990) 1.96
Liver blood flow measured by portal venous and hepatic arterial routes with Kr-85. Am J Physiol (1966) 1.93
Serotonin and lysergic acid diethylamide binding in rat brain membranes: relationship to postsynaptic serotonin receptors. Mol Pharmacol (1976) 1.93
Human amnion as an adjunct in wound healing. Lancet (1980) 1.92
Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study. Neurology (2002) 1.90
Neuroleptic medications inhibit complex I of the electron transport chain. Ann Neurol (1993) 1.82
Mitochondrial abnormalities in non-alcoholic steatohepatitis. J Hepatol (1999) 1.81
Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease. Proc Natl Acad Sci U S A (1997) 1.80
Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines. Exp Neurol (2000) 1.80
The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Mol Cell Biol (1996) 1.75
Synaptic biochemistry of amino acids. Fed Proc (1973) 1.74
Phenotypic variation in biotinidase deficiency. J Pediatr (1983) 1.74
Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency. Nature (1976) 1.71
Optimizing the ongoing search for new treatments for Parkinson disease: using futility designs. Neurology (2006) 1.69
Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease. Neurology (1990) 1.67
Isolation and some properties of macrophage alpha-actinin: evidence that it is not an actin gelling protein. Biochemistry (1984) 1.61
A defect in mitochondrial electron-transport activity (NADH-coenzyme Q oxidoreductase) in Leber's hereditary optic neuropathy. N Engl J Med (1989) 1.61
Clinical correlates of sleep benefit in Parkinson's disease. Neurology (1997) 1.58
Use of cytochalasin B to distinguish between early and late events in neutrophil activation. Biochim Biophys Acta (1980) 1.56
Stress and burnout in oncology. Oncology (Williston Park) (2000) 1.56
Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts. J Immunol (2000) 1.55
Differences in the corticospinal projection from primary motor cortex and supplementary motor area to macaque upper limb motoneurons: an anatomical and electrophysiological study. Cereb Cortex (2002) 1.55
Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range. J Physiol (1981) 1.52
Treatment of chronic ulceration of the legs with human amnion. Lancet (1980) 1.51
Role of mitochondria in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2000) 1.51
Stimulus-secretion coupling in rabbit neutrophils is not mediated by phosphatidylinositol breakdown. Nature (1980) 1.47
Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease. Biochim Biophys Acta (1997) 1.44
Reduced platelet cytochrome c oxidase activity in Alzheimer's disease. Neurology (1994) 1.43
The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin. Biochem J (1981) 1.41
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. Oncogene (1994) 1.40
Direct identification and characterisation of beta-adrenergic receptors in rat brain. Nature (1975) 1.40
The assessment of diaphragm function. Medicine (Baltimore) (1977) 1.39
The CASE adherence index: A novel method for measuring adherence to antiretroviral therapy. AIDS Care (2006) 1.39
Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease. J Neurosci (1997) 1.36
Inhibition of release of dopamine- -hydroxylase and norepinephrine from sympathetic nerves by colchicine, vinblastine, or cytochalasin-B (hypogastric nerve stimulation-exocytosis-microtubules-microfilaments-guinea pig). Proc Natl Acad Sci U S A (1972) 1.36
Comparison of potential markers of farnesyltransferase inhibition. Clin Cancer Res (2000) 1.32
Efficacy of a telephone follow-up system in the emergency department. J Emerg Med (1988) 1.32
Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex. Nature (1980) 1.31
Neurotransmitter receptors in the brain: biochemical identification. Annu Rev Physiol (1976) 1.30
Enhanced release of dopamine -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline. Mol Pharmacol (1973) 1.27
Pathophysiologic effects of bowel distention on intestinal blood flow. Am J Surg (1969) 1.27
Genome-wide scan for Parkinson's disease: the GenePD Study. Neurology (2001) 1.25
On the mechanism of release of norepinephrine from sympathetic nerves induced by depolarizing agents and sympathomimetic drugs. Mol Pharmacol (1975) 1.23
The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. Biochim Biophys Acta (1999) 1.23
Biochemical and genetic analysis of Salmonella typhimurium and Escherichia coli mutants defective in specific incorporation of selenium into formate dehydrogenase and tRNAs. Biofactors (1989) 1.22
In vivo and in vitro collagenolytic activity of Acanthamoeba castellanii. Invest Ophthalmol Vis Sci (1990) 1.21
Supportive and negative responses in the partner relationship: their association with psychological adjustment among individuals with cancer. J Behav Med (1997) 1.21
Agonists vs levodopa in PD: the thrilla of whitha. Neurology (2003) 1.21
f-MetLeuPhe-induced phosphatidylinositol turnover in rabbit neutrophils is dependent on extracellular calcium. FEBS Lett (1980) 1.21
Mitochondrial function in Parkinson's disease. Lancet (1989) 1.20
Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways. Ann Neurol (2000) 1.20
Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase. Naunyn Schmiedebergs Arch Pharmacol (1972) 1.19
The effect of Parkinson's disease on interference control during action selection. Neuropsychologia (2008) 1.19
Multiplex fluorescence-based primer extension method for quantitative mutation analysis of mitochondrial DNA and its diagnostic application for Alzheimer's disease. Nucleic Acids Res (1997) 1.18
The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity. Mol Cell Biol (2000) 1.18
Pharmaceutical representatives and emergency medicine residents: a national survey. Ann Emerg Med (1993) 1.17
Cytochrome c oxidase in Alzheimer's disease brain: purification and characterization. Neurology (1995) 1.17
An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res Brain Res Rev (1999) 1.17
Interrelationships of the volume and time components of individual breaths in resting man. J Physiol (1975) 1.16