PubRank

B Bettler

Author PubWeight™ 59.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 1998 4.33
2 Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature 1997 3.22
3 Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature 1998 2.72
4 Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron 2001 2.51
5 Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol 2001 2.32
6 Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function. EMBO J 2001 2.28
7 Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA. Nature 1991 2.25
8 International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function. Pharmacol Rev 2002 2.15
9 Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron 1994 2.15
10 GABAB receptors - the first 7TM heterodimers. Trends Pharmacol Sci 1999 1.94
11 C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. J Neurosci 2001 1.90
12 Subunit composition of kainate receptors in hippocampal interneurons. Neuron 2000 1.66
13 Expression, structure, and function of the CD23 antigen. Adv Immunol 1991 1.46
14 Intracellular retention of recombinant GABAB receptors. J Biol Chem 1998 1.33
15 GABAB receptor protein and mRNA distribution in rat spinal cord and dorsal root ganglia. Eur J Neurosci 2000 1.27
16 The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Mol Pharmacol 1999 1.24
17 Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit. Mol Pharmacol 2000 1.19
18 Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding. J Biol Chem 1999 1.18
19 Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors. Neuropharmacology 1999 1.18
20 Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors. J Biol Chem 2000 1.16
21 Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. J Comp Neurol 1999 1.14
22 Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels. Proc Natl Acad Sci U S A 1998 1.10
23 gamma-aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution. J Biol Chem 1999 1.02
24 Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience 2006 1.01
25 The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini. Neuropharmacology 1999 0.98
26 Presynaptic and postsynaptic localization of GABA(B) receptors in neurons of the rat retina. Eur J Neurosci 1998 0.98
27 Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell Death Dis 2012 0.97
28 Subcellular localization of GABA(B) receptor subunits in rat visual cortex. J Comp Neurol 2001 0.96
29 Cytokine effects of CD23 are mediated by an epitope distinct from the IgE binding site. EMBO J 1992 0.94
30 Spatial distribution of kainate receptor subunit mRNA in the mouse basal ganglia and ventral mesencephalon. J Comp Neurol 1997 0.89
31 Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene: evaluation of its involvement in idiopathic generalized epilepsy. Neurogenetics 1998 0.89
32 Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain. Mol Cell Neurosci 1998 0.88
33 Native and recombinant soluble CD23 fragments with IgE suppressive activity. Immunology 1992 0.87
34 gamma-aminobutyric acid type B receptors are expressed and functional in mammalian cardiomyocytes. Proc Natl Acad Sci U S A 2000 0.86
35 Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. Eur J Neurosci 1999 0.83
36 Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy. Am J Med Genet 1999 0.83
37 The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 1993 0.81
38 Ligands for the isolation of GABA(B) receptors [corrected] . Neuropharmacology 1999 0.77
39 Molecular biology of the glutamate receptors. Clin Neuropharmacol 1992 0.77
40 GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice. Am J Physiol Endocrinol Metab 2007 0.77
41 Differential localization of GABA(B) receptors in the mouse retina. Neuroreport 1998 0.77
42 Sex differences in insulin resistance in GABAB1 knockout mice. Life Sci 2012 0.77
43 Ontogenic expression of anterior pituitary GABA(B) receptor subunits. Neuropharmacology 2001 0.76
44 Characterisation and partial purification of the GABA(B) receptor from the rat cerebellum using the novel antagonist [3H]CGP 62349. Brain Res Mol Brain Res 1999 0.75
45 Ligands for expression cloning and isolation of GABA(B) receptors. Farmaco 2001 0.75
46 Processing of GABABR1 in heterologous expression systems. Ann N Y Acad Sci 1999 0.75