Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.
|
Science
|
1999
|
6.37
|
2
|
Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study.
|
Behav Brain Res
|
1983
|
2.46
|
3
|
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
|
Nat Med
|
2000
|
2.34
|
4
|
Glutamate antagonists limit tumor growth.
|
Proc Natl Acad Sci U S A
|
2001
|
1.88
|
5
|
Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis.
|
Brain Res
|
1984
|
1.59
|
6
|
Excitatory amino acids and the basal ganglia: implications for the therapy of Parkinson's disease.
|
Trends Neurosci
|
1989
|
1.57
|
7
|
Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures.
|
Epilepsia
|
1992
|
1.57
|
8
|
Glutamate: a new target in schizophrenia?
|
Trends Pharmacol Sci
|
1990
|
1.43
|
9
|
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
|
Proc Natl Acad Sci U S A
|
2000
|
1.21
|
10
|
The susceptibility of rats to pilocarpine-induced seizures is age-dependent.
|
Brain Res
|
1987
|
1.20
|
11
|
N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain.
|
Proc Natl Acad Sci U S A
|
1999
|
1.20
|
12
|
Cholinomimetics produce seizures and brain damage in rats.
|
Experientia
|
1983
|
1.18
|
13
|
NMDA antagonists potentiate antiparkinsonian actions of L-dopa in monoamine-depleted rats.
|
Ann Neurol
|
1990
|
1.11
|
14
|
Antiepileptic drugs and the developing brain.
|
Cell Mol Life Sci
|
2006
|
1.04
|
15
|
Alprazolam dependence prevented by substituting with the beta-carboline abecarnil.
|
Proc Natl Acad Sci U S A
|
1997
|
1.01
|
16
|
Diazepam dependence prevented by glutamate antagonists.
|
Proc Natl Acad Sci U S A
|
1993
|
1.00
|
17
|
Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.
|
Neuroscience
|
1986
|
0.99
|
18
|
Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.
|
Neuroreport
|
1996
|
0.96
|
19
|
The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys.
|
Ann Neurol
|
1991
|
0.94
|
20
|
Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
|
J Pharmacol Exp Ther
|
1990
|
0.94
|
21
|
Spontaneous recurrent seizures in rats: amino acid and monoamine determination in the hippocampus.
|
Epilepsia
|
1994
|
0.93
|
22
|
Muscle relaxant action of excitatory amino acid antagonists.
|
Neurosci Lett
|
1985
|
0.92
|
23
|
Only certain antiepileptic drugs prevent seizures induced by pilocarpine.
|
Brain Res
|
1987
|
0.92
|
24
|
Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants.
|
J Pharmacol Exp Ther
|
1993
|
0.91
|
25
|
Excitotoxicity and neurodegenerative diseases.
|
Curr Opin Neurol
|
1995
|
0.90
|
26
|
Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen.
|
Proc Natl Acad Sci U S A
|
1987
|
0.89
|
27
|
Convulsant action of morphine, [D-Ala2, D-Leu5]-enkephalin and naloxone in the rat amygdala: electroencephalographic, morphological and behavioural sequelae.
|
Neuroscience
|
1987
|
0.88
|
28
|
Seizures produced by pilocarpine: neuropathological sequelae and activity of glutamate decarboxylase in the rat forebrain.
|
Brain Res
|
1986
|
0.87
|
29
|
Abecarnil: a novel anxiolytic with mixed full agonist/partial agonist properties in animal models of anxiety and sedation.
|
Psychopharmacol Ser
|
1993
|
0.87
|
30
|
Susceptibility to seizures produced by pilocarpine in rats after microinjection of isoniazid or gamma-vinyl-GABA into the substantia nigra.
|
Brain Res
|
1986
|
0.86
|
31
|
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.
|
Proc Natl Acad Sci U S A
|
1996
|
0.86
|
32
|
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease.
|
J Neural Transm Park Dis Dement Sect
|
1991
|
0.85
|
33
|
Long-term treatment with abecarnil does not induce diazepam-like dependence in mice.
|
J Pharmacol Exp Ther
|
1993
|
0.84
|
34
|
Injections of picrotoxin and bicuculline into the amygdaloid complex of the rat: an electroencephalographic, behavioural and morphological analysis.
|
Neuroscience
|
1985
|
0.84
|
35
|
Neurodegenerative disorders: clues from glutamate and energy metabolism.
|
Crit Rev Neurobiol
|
1996
|
0.84
|
36
|
Intrahippocampal bethanechol in rats: behavioural, electroencephalographic and neuropathological correlates.
|
Behav Brain Res
|
1983
|
0.82
|
37
|
Intrastriatal N-methyl-D-aspartate prevents amygdala kindled seizures in rats.
|
Brain Res
|
1986
|
0.82
|
38
|
Disinhibition of nigral GABA output neurons mediates muscular rigidity elicited by striatal opioid receptor stimulation.
|
Life Sci
|
1983
|
0.82
|
39
|
Anticonvulsant action of 1,3-dimethyl-5-aminoadamantane. Pharmacological studies in rodents and baboon, Papio papio.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1986
|
0.81
|
40
|
Effects of 7-nitroindazole, NG-nitro-L-arginine, and D-CPPene on harmaline-induced postural tremor, N-methyl-D-aspartate-induced seizures, and lisuride-induced rotations in rats with nigral 6-hydroxydopamine lesions.
|
Eur J Pharmacol
|
1996
|
0.81
|
41
|
Differential effects of non-steroidal anti-inflammatory drugs on seizures produced by pilocarpine in rats.
|
Brain Res
|
1988
|
0.81
|
42
|
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
|
Epilepsia
|
1981
|
0.81
|
43
|
Effects of morphine and naloxone on pilocarpine-induced convulsions in rats.
|
Neuropeptides
|
1985
|
0.81
|
44
|
Paradoxical convulsant action of a novel non-competitive N-methyl-D-aspartate (NMDA) antagonist, tiletamine.
|
Brain Res
|
1988
|
0.81
|
45
|
Kindling to the benzodiazepine receptor inverse agonist, FG 7142: evidence for involvement of NMDA, but not non-NMDA, glutamatergic receptors.
|
Neuropharmacology
|
1993
|
0.81
|
46
|
Prevention of trauma-induced neurodegeneration in infant and adult rat brain: glutamate antagonists.
|
Metab Brain Dis
|
1996
|
0.80
|
47
|
Role of muscarinic cholinergic mechanisms in the substantia nigra pars reticulata in mediating muscular rigidity in rats.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1984
|
0.80
|
48
|
Evidence that antagonism at non-NMDA receptors results in anticonvulsant action.
|
Eur J Pharmacol
|
1987
|
0.80
|
49
|
Studies on the mechanism of wet dog shakes produced by carbachol in rats.
|
Pharmacology
|
1984
|
0.80
|
50
|
Reversal of the muscle relaxant effect of diazepam but not of progabide by a specific benzodiazepine antagonist: Ro 15-1788.
|
Eur J Pharmacol
|
1983
|
0.79
|
51
|
MPTP-induced degeneration: interference with glutamatergic toxicity.
|
J Neural Transm Suppl
|
1994
|
0.79
|
52
|
Neurochemical changes in the hippocampus of rats with spontaneous recurrent seizures.
|
Epilepsy Res Suppl
|
1992
|
0.79
|
53
|
Anticonvulsant action of phenobarbital, diazepam, carbamazepine, and diphenylhydantoin in the electroshock test in mice after lesion of hippocampal pyramidal cells with intracerebroventricular kainic acid.
|
Epilepsia
|
1982
|
0.79
|
54
|
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist?
|
Brain Res
|
1985
|
0.79
|
55
|
Anticonvulsant action of stereoisomers of gamma-glutamylaminomethylsulphonic acid in mice.
|
Eur J Pharmacol
|
1985
|
0.79
|
56
|
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
|
Brain Res
|
1985
|
0.79
|
57
|
Is the muscle relaxant effect of diazepam in spastic mutant rats mediated through GABA-independent benzodiazepine receptors?
|
Neurosci Lett
|
1983
|
0.78
|
58
|
Nigral GABAergic mechanisms and EMG activity in rats: differences between pars reticulata and pars compacta.
|
Eur J Pharmacol
|
1983
|
0.78
|
59
|
Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia.
|
Ann Neurol
|
1993
|
0.78
|
60
|
Delta-aminovaleric acid antagonizes the pharmacological actions of baclofen in the central nervous system.
|
Exp Brain Res
|
1988
|
0.78
|
61
|
The rat ventromedial thalamic nucleus and motor control: role of N-methyl-D-aspartate-mediated excitation, GABAergic inhibition, and muscarinic transmission.
|
J Neurosci
|
1986
|
0.78
|
62
|
Pharmacology of the AMPA antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo-(F)-quinoxaline.
|
Ann N Y Acad Sci
|
1997
|
0.78
|
63
|
Role of opioid receptors in the substantia nigra in morphine-induced muscular rigidity.
|
Life Sci
|
1983
|
0.78
|
64
|
Effects of kainic acid on body temperature of rats: role of catecholaminergic and serotonergic systems.
|
Psychopharmacology (Berl)
|
1980
|
0.78
|
65
|
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents.
|
Neurosci Lett
|
1987
|
0.77
|
66
|
Interaction between phenytoin and diazepam in mutant Han-Wistar rats with progressive spastic paresis.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1982
|
0.77
|
67
|
ZK 91296, an anticonvulsant beta-carboline which lacks muscle relaxant properties.
|
Eur J Pharmacol
|
1985
|
0.77
|
68
|
What are the differences between abecarnil and conventional benzodiazepine anxiolytics?
|
Adv Biochem Psychopharmacol
|
1992
|
0.77
|
69
|
Motor actions of excitatory amino acids and their antagonists within the rat ventromedial thalamic nucleus.
|
Brain Res
|
1986
|
0.77
|
70
|
Effect of aminophylline on muscle relaxant action of diazepam and phenobarbitone in genetically spastic rats: further evidence for a purinergic mechanism in the action of diazepam.
|
Eur J Pharmacol
|
1984
|
0.77
|
71
|
A specific benzodiazepine antagonist CGS 8216 reverses the muscle relaxant effect of diazepam but not that of phenobarbitone.
|
Eur J Pharmacol
|
1984
|
0.77
|
72
|
Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity.
|
Neurosci Lett
|
1985
|
0.76
|
73
|
Evidence against the involvement of serotonergic mechanisms in wet dog shake behavior induced by carbachol chloride in rats.
|
Psychopharmacology (Berl)
|
1981
|
0.76
|
74
|
Anticonvulsant role of adenosine.
|
Pol J Pharmacol Pharm
|
1989
|
0.76
|
75
|
Microinjections of the gamma-aminobutyrate antagonist, bicuculline methiodide, into the caudate-putamen prevent amygdala-kindled seizures in rats.
|
Brain Res
|
1987
|
0.76
|
76
|
Kainic acid-induced wet dog shakes in rats. The relation to central neurotransmitters.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1980
|
0.76
|
77
|
Catalepsy after microinjection of haloperidol into the rat medial prefrontal cortex.
|
Exp Brain Res
|
1988
|
0.76
|
78
|
The involvement of catecholaminergic mechanisms in the appearance of wet dog shakes produced by carbachol chloride in rats.
|
Arch Int Pharmacodyn Ther
|
1982
|
0.76
|
79
|
Studies of carbachol-induced wet-dog shake behavior in rats.
|
Psychopharmacology (Berl)
|
1981
|
0.76
|
80
|
Rigidity and catalepsy after injections of muscimol into the ventromedial thalamic nucleus: an electromyographic study in the rat.
|
Exp Brain Res
|
1985
|
0.76
|
81
|
(RS)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid: wet dog shakes, catalepsy and body temperature changes in rats.
|
Pharmacol Biochem Behav
|
1981
|
0.76
|
82
|
Dopamine control of seizure propagation: intranigral dopamine D1 agonist SKF-38393 enhances susceptibility to seizures.
|
Synapse
|
1990
|
0.75
|
83
|
Evaluation of the muscle relaxant properties of a novel beta-carboline, ZK 93423 in rats and cats.
|
Br J Pharmacol
|
1985
|
0.75
|
84
|
Effects of the antiparkinsonian drug budipine on central neurotransmitter systems.
|
Eur J Pharmacol
|
1996
|
0.75
|
85
|
Inhibition of cisplatin-induced emesis in ferrets by the non-NMDA receptor antagonists NBQX and CNQX.
|
Neurosci Lett
|
1992
|
0.75
|
86
|
Intraamygdaloid morphine produces seizures and brain damage in rats.
|
Life Sci
|
1983
|
0.75
|
87
|
Effects of 2-chloroadenosine on amygdaloid and hippocampal kindled seizures.
|
Arch Int Pharmacodyn Ther
|
1985
|
0.75
|
88
|
The role of the substantia nigra in motility of the rat. Muscular rigidity, body asymmetry and catalepsy after injection of morphine into the nigra.
|
Neuropharmacology
|
1983
|
0.75
|
89
|
Dyphenylhydantoin enhancement of diazepam effects on locomotor activity in mice.
|
Psychopharmacology (Berl)
|
1982
|
0.75
|
90
|
Diphenylhydantoin potentiates the protective effect of diazepam against pentylenetetrazol but not against bicuculline and isoniazid-induced seizures in mice.
|
Neuropharmacology
|
1981
|
0.75
|
91
|
Reversal of the muscle relaxant effect of diazepam by the specific benzodiazepine antagonist Ro 15-1788: an electromyographic study in morphine model of muscular rigidity in rats.
|
Life Sci
|
1983
|
0.75
|
92
|
[The influence of atropine on the antiamphetaminic action of fluphenazine (author's transl)].
|
Ann Univ Mariae Curie Sklodowska Med
|
1979
|
0.75
|
93
|
Myorelaxant effect after intrathecal injection of antispastic drugs in rats.
|
Neurosci Lett
|
1989
|
0.75
|
94
|
The threshold for limbic seizures in rats is decreased by intranigral morphine.
|
NIDA Res Monogr
|
1986
|
0.75
|
95
|
Effects of morphine, nalorphine and morphine withdrawal on lethal toxicity of intracerebroventricular kainic acid in mice.
|
Pol J Pharmacol Pharm
|
1981
|
0.75
|
96
|
Substantia nigra and entopeduncular nucleus: supraspinal sites of the muscle relaxant action of tizanidine.
|
Brain Res
|
1986
|
0.75
|
97
|
On the possible role of excitatory amino acids in the striatum in mediating morphine-induced muscular rigidity.
|
Pharmacol Biochem Behav
|
1982
|
0.75
|
98
|
Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction.
|
Brain Res
|
1985
|
0.75
|
99
|
Distinct sites of functional interaction between dopamine, acetylcholine and gamma-aminobutyrate within the neostriatum: an electromyographic study in rats.
|
Neuroscience
|
1986
|
0.75
|
100
|
Effects of morphine and nalorphine on kainic acid-induced hypothermia in rats.
|
Psychopharmacology (Berl)
|
1981
|
0.75
|
101
|
Does morphine withdrawal produce brain damage in rats?
|
Life Sci
|
1983
|
0.75
|
102
|
GABAergic mechanisms in mediating muscular rigidity, catalepsy and postural asymmetry in rats: differences between dorsal and ventral striatum.
|
Brain Res
|
1984
|
0.75
|
103
|
Evidence for functional interactions of morphine in substantia nigra and striatum in relation to muscular rigidity in rats.
|
Neurosci Lett
|
1982
|
0.75
|
104
|
The locomotor and exploratory activities in rats after lesion of hippocampal pyramidal cells with kainic acid.
|
Pol J Pharmacol Pharm
|
1981
|
0.75
|
105
|
Phosphonic analogues of excitatory amino acids raise the threshold for maximal electroconvulsions in mice.
|
Neurosci Res
|
1985
|
0.75
|
106
|
Effect of aminophylline and enprofylline on the protective efficacy of common antiepileptic drugs against electroconvulsions in mice.
|
Epilepsia
|
1987
|
0.75
|
107
|
Effect of aminophylline on the protective action of common antiepileptic drugs against electroconvulsions in mice.
|
Epilepsia
|
1986
|
0.75
|
108
|
The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist.
|
J Neural Transm Park Dis Dement Sect
|
1993
|
0.75
|
109
|
Role of GABAergic mechanisms in the substantia nigra pars reticulata in modulating morphine-induced muscular rigidity in rats.
|
Neurosci Lett
|
1982
|
0.75
|
110
|
Effect of combined treatment of phenytoin with diazepam on the susceptibility of mice to electroconvulsions.
|
J Pharm Pharmacol
|
1981
|
0.75
|
111
|
Prevention of kainic acid-induced seizure-like activity by antiepileptic drugs.
|
Pol J Pharmacol Pharm
|
1981
|
0.75
|
112
|
Induction of wet dog shakes by intracerebroventricular bethanechol in rats. Antagonism by neurotransmitter receptor blockers.
|
Pharmacology
|
1982
|
0.75
|
113
|
Excitatory amino acids--quo vadis?
|
Braz J Med Biol Res
|
1989
|
0.75
|
114
|
Effect of antidepressant drugs on carbachol chloride-induced wet dog shake behaviour in rats.
|
Neuropharmacology
|
1981
|
0.75
|
115
|
Effect of glutamic acid diethylester on (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and kainic acid-induced changes of body temperature in rats.
|
Pol J Pharmacol Pharm
|
1982
|
0.75
|
116
|
Muscle relaxant action of phenobarbitone in genetically spastic rats: an electromyographic study.
|
Eur J Pharmacol
|
1986
|
0.75
|
117
|
The locomotor and stereotype response to dopaminergic drugs and caffeine after intracerebroventricular kainic acid in rats.
|
Pol J Pharmacol Pharm
|
1982
|
0.75
|
118
|
Biochemical consequences of kainic acid injection into the lateral brain ventricle in rat.
|
Acta Biochim Pol
|
1981
|
0.75
|
119
|
Effects of combined treatment with diphenylhydantoin and different benzodiazepines on pentylenetetrazol- and bicuculline-induced seizures in mice.
|
Neuropharmacology
|
1982
|
0.75
|
120
|
Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents.
|
Neuroscience
|
1987
|
0.75
|
121
|
Shuttle behavior in rats after lesion of hippocampal pyramidal cells with kainic acid.
|
Methods Find Exp Clin Pharmacol
|
1982
|
0.75
|
122
|
Convulsant action of naloxone in the rat amygdala.
|
NIDA Res Monogr
|
1986
|
0.75
|
123
|
Muscle relaxant action of 2-chloroadenosine in genetically spastic rats is independent of gamma-aminobutyric acid-mediated inhibition.
|
Neurosci Lett
|
1985
|
0.75
|
124
|
Effects of excitatory amino-acid antagonists on the anticonvulsant action of phenobarbital or diphenylhydantoin in mice.
|
Eur J Pharmacol
|
1984
|
0.75
|
125
|
Bilateral injection of kainic acid into the rat striatum potentiates morphine, arecoline and pilocarpine but not haloperidol catalepsy.
|
Methods Find Exp Clin Pharmacol
|
1982
|
0.75
|
126
|
Convulsant action of pentetrazol in rats with selective lesions of the hippocampal pyramidal cells with intracerebroventricular kainic acid.
|
Methods Find Exp Clin Pharmacol
|
1982
|
0.75
|
127
|
Effect of trazodone, mianserin, iprindole and zimelidine on wet dog shakes produced by carbachol in rats.
|
J Pharm Pharmacol
|
1981
|
0.75
|
128
|
The role of striatal cholinergic mechanisms for the development of limb rigidity: an electromyographic study in rats.
|
Brain Res
|
1986
|
0.75
|
129
|
Atropine reversal of kainic acid-induced decrease in the leptazol convulsive threshold.
|
J Pharm Pharmacol
|
1981
|
0.75
|
130
|
CGS 8216, Ro 15-1788 and methyl-beta-carboline-3-carboxylate, but not EMD 41717 antagonize the muscle relaxant effect of diazepam in genetically spastic rats.
|
Life Sci
|
1984
|
0.75
|
131
|
Effects of methyl beta-carboline-3-carboxylate, Ro 15-1788 and CGS 8216 on muscle tone in genetically spastic rats.
|
Eur J Pharmacol
|
1985
|
0.75
|
132
|
Evidence that opioid receptors in the substantia nigra pars reticulata are relevant in regulating the function of striatal efferent pathways.
|
Behav Brain Res
|
1982
|
0.75
|
133
|
Stereotypy, locomotor and cataleptic effects produced by drugs influencing dopaminergic systems in a mutant strain of Wistar rats: a genuine model of basal ganglia dysfunction?
|
Behav Brain Res
|
1984
|
0.75
|
134
|
Modification of the anticonvulsant activity of 2-amino-5-phosphonovalerate by agents affecting different neurotransmitter systems.
|
Neuropharmacology
|
1985
|
0.75
|
135
|
Aminophylline and CGS 8216 reverse the protective action of diazepam against electroconvulsions in mice.
|
Epilepsia
|
1986
|
0.75
|