Published in J Cell Sci on February 01, 1999
Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization. Proc Natl Acad Sci U S A (2000) 2.46
Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J Cell Biol (1999) 1.65
Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am J Pathol (2002) 1.63
Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis. J Clin Invest (2000) 1.60
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest (2014) 1.59
Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro. Am J Pathol (2001) 1.42
Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. Am J Pathol (2004) 1.39
Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Mol Cell Biol (2007) 1.37
Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. Am J Pathol (2004) 1.33
Diminished callus size and cartilage synthesis in alpha 1 beta 1 integrin-deficient mice during bone fracture healing. Am J Pathol (2002) 1.05
Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Mol Cell Biol (2010) 1.00
Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome. Am J Pathol (2008) 0.97
Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney. Fibrogenesis Tissue Repair (2010) 0.96
Integrins in kidney disease. J Am Soc Nephrol (2013) 0.95
Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer. Cancer Res (2008) 0.94
Adenoviral overexpression and small interfering RNA suppression demonstrate that plasminogen activator inhibitor-1 produces elevated collagen accumulation in normal and keloid fibroblasts. Am J Pathol (2008) 0.90
Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis. Am J Pathol (2002) 0.90
Integrins in Wound Healing. Adv Wound Care (New Rochelle) (2014) 0.90
Structure of collagen receptor integrin α(1)I domain carrying the activating mutation E317A. J Biol Chem (2011) 0.87
Progressive morphological and functional defects in retinas from alpha1 integrin-null mice. Invest Ophthalmol Vis Sci (2008) 0.85
Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis. J Biol Chem (2012) 0.85
Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy. Kidney Int (2012) 0.85
Integrin Regulation of Epidermal Functions in Wounds. Adv Wound Care (New Rochelle) (2014) 0.85
Endothelial cells enhance the in vivo bone-forming ability of osteogenic cell sheets. Lab Invest (2014) 0.84
The role of cell-extracellular matrix interactions in glomerular injury. Exp Cell Res (2012) 0.84
Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Mol Biol Cell (2014) 0.84
Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring. Am J Pathol (2014) 0.83
The crucial role of collagen-binding integrins in maintaining the mechanical properties of human scleral fibroblasts-seeded collagen matrix. Mol Vis (2011) 0.83
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice. Am J Pathol (2011) 0.82
Reduced granulation tissue and wound strength in the absence of α11β1 integrin. J Invest Dermatol (2015) 0.81
Collagen matrix as a tool in studying fibroblastic cell behavior. Cell Adh Migr (2015) 0.80
Osteoblast lineage cells can discriminate microscale topographic features on titanium-aluminum-vanadium surfaces. Ann Biomed Eng (2014) 0.80
Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation. J Oncol (2011) 0.79
Collagen Accumulation in Osteosarcoma Cells lacking GLT25D1 Collagen Galactosyltransferase. J Biol Chem (2016) 0.78
Lack of alpha-1 integrin alters lesion morphology during pulmonary Mycobacterium tuberculosis infection. Tuberculosis (Edinb) (2008) 0.77
Role of integrin subunits in mesenchymal stem cell differentiation and osteoblast maturation on graphitic carbon-coated microstructured surfaces. Biomaterials (2015) 0.77
Do cell junction protein mutations cause an airway phenotype in mice or humans? Am J Respir Cell Mol Biol (2011) 0.77
Role of Hypoxia-Inducible Factors in the Development of Liver Fibrosis. Cell Mol Gastroenterol Hepatol (2015) 0.77
Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View. Curr Top Membr (2015) 0.76
Chronic Wound Dressings Based on Collagen-Mimetic Proteins. Adv Wound Care (New Rochelle) (2015) 0.76
Discoidin Receptor 2 Controls Bone Formation and Marrow Adipogenesis. J Bone Miner Res (2016) 0.75
Entry of coxsackievirus A9 into host cells: specific interactions with alpha v beta 3 integrin, the vitronectin receptor. Virology (1994) 1.96
Expression of integrins and basement membrane components by wound keratinocytes. J Clin Invest (1993) 1.80
Induced expression of syndecan in healing wounds. J Cell Biol (1991) 1.67
Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J Cell Biol (1999) 1.65
Satellite cell proliferation and the expression of myogenin and desmin in regenerating skeletal muscle: evidence for two different populations of satellite cells. Lab Invest (1995) 1.62
Regulation of cell adhesion receptors by transforming growth factor-beta. Regulation of vitronectin receptor and LFA-1. J Biol Chem (1989) 1.57
Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression. J Biol Chem (1995) 1.56
Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development. Dev Dyn (1997) 1.44
Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I, and alpha 10I domains. J Biol Chem (2001) 1.44
Entry of human parechovirus 1. J Virol (2001) 1.39
Elevation of serum gamma-glutamyltranspeptidase activity is frequent in chronic hepatitis C, and is associated with insulin resistance. Dig Liver Dis (2009) 1.39
Disc degeneration in magnetic resonance imaging. A comparative biochemical, histologic, and radiologic study in cadaver spines. Spine (Phila Pa 1976) (1991) 1.38
Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J Biol Chem (1999) 1.37
EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival. Oncogene (2006) 1.37
A protease of Bacteroides gingivalis degrades cell surface and matrix glycoproteins of cultured gingival fibroblasts and induces secretion of collagenase and plasminogen activator. Infect Immun (1989) 1.35
Interleukin-1 increases collagen production and mRNA levels in cultured skin fibroblasts. Biochim Biophys Acta (1987) 1.25
PPAR-gamma agonist protects podocytes from injury. Kidney Int (2007) 1.23
Yeast-derived hepatitis B vaccine in dental students. A three-year follow-up study. Vaccine (1990) 1.22
Distinct recognition of collagen subtypes by alpha(1)beta(1) and alpha(2)beta(1) integrins. Alpha(1)beta(1) mediates cell adhesion to type XIII collagen. J Biol Chem (2000) 1.19
Increased expression of aquaporin 3 in atopic eczema. Allergy (2006) 1.16
Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney Int (2006) 1.15
Vitamin E neuroprotection for cisplatin neuropathy: a randomized, placebo-controlled trial. Neurology (2010) 1.15
Are serum inflammatory markers age dependent in acute appendicitis? J Am Coll Surg (1997) 1.13
Adhesion receptors and cell invasion: mechanisms of integrin-guided degradation of extracellular matrix. Cell Mol Life Sci (2000) 1.13
Luminosity-independent measurement of the proton-proton total cross section at √s=8 TeV. Phys Rev Lett (2013) 1.13
Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta. Cell Growth Differ (1997) 1.12
Population-based study of the surgical workload and economic impact of bowel obstruction caused by postoperative adhesions. Br J Surg (2003) 1.10
Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events. Mol Cell Biol (1991) 1.10
Novel serum inflammatory markers in acute appendicitis. Scand J Clin Lab Invest (2002) 1.09
Expression of collagenase-3 (matrix metalloproteinase-13) in transitional-cell carcinoma of the urinary bladder. Int J Cancer (2000) 1.08
Comparative effects of interleukin-1 and tumor necrosis factor-alpha on collagen production and corresponding procollagen mRNA levels in human dermal fibroblasts. J Invest Dermatol (1991) 1.05
Echovirus 1 infection induces both stress- and growth-activated mitogen-activated protein kinase pathways and regulates the transcription of cellular immediate-early genes. Virology (1998) 1.03
Exulceratio simplex as conceivable cause of massive gastric hemorrhage. Surg Gynecol Obstet (1982) 1.02
Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroids. Am J Pathol (1999) 1.01
Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes on fibronectin. Cell Adhes Commun (1999) 1.01
Prognostic factors in prostate cancer. Diagn Pathol (2006) 0.99
Regulation of integrin-type cell adhesion receptors by cytokines. J Biol Chem (1991) 0.99
Transforming growth factor-beta regulates collagen gel contraction by increasing alpha 2 beta 1 integrin expression in osteogenic cells. J Biol Chem (1995) 0.97
A novel type of arabinoxylan arabinofuranohydrolase isolated from germinated barley analysis of substrate preference and specificity by nano-probe NMR. Eur J Biochem (2000) 0.96
Tumor necrosis factor alpha inhibits wound healing in the rat. Eur Surg Res (1991) 0.95
Integrin alpha(2)I domain recognizes type I and type IV collagens by different mechanisms. J Biol Chem (2000) 0.95
Integrin alpha2beta1-dependent contraction of floating collagen gels and induction of collagenase are inhibited by tyrosine kinase inhibitors. Exp Cell Res (1996) 0.94
Expression of integrin family of cell adhesion receptors in rheumatoid synovium. Alpha 6 integrin subunit in normal and hyperplastic synovial lining cell layer. Am J Pathol (1993) 0.94
Integrin and dystrophin associated adhesion protein complexes during regeneration of shearing-type muscle injury. Neuromuscul Disord (2000) 0.93
Integrin alpha 2 beta 1 in tumorigenic human osteosarcoma cell lines regulates cell adhesion, migration, and invasion by interaction with type I collagen. Cell Growth Differ (1996) 0.93
The detection and biological activity of human antibodies to IL-2 in normal donors. Scand J Immunol (1993) 0.93
Inhibin gene expression in a large cell calcifying Sertoli cell tumour and serum inhibin and activin levels. APMIS (1998) 0.92
Stimulation of wound healing by epidermal growth factor. A dose-dependent effect. Ann Surg (1986) 0.92
Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban. Exp Cell Res (2006) 0.91
Epithelial integrins with special reference to oral epithelia. J Dent Res (2011) 0.90
Magnetization transfer imaging of lumbar disc degeneration. Correlation of relaxation parameters with biochemistry. Spine (Phila Pa 1976) (1994) 0.90
Basic fibroblast growth factor-syndecan complex at cell surface or immobilized to matrix promotes cell growth. J Biol Chem (1992) 0.90
Gingival crevicular fluid fibronectin degradation in periodontal health and disease. Scand J Dent Res (1989) 0.90
Rationale for tilted implants: FEA considerations and clinical reports. Oral Implantol (Rome) (2012) 0.90
Increased glycosylation of beta 1 integrins affects the interaction of transformed S115 mammary epithelial cells with laminin-1. Cell Growth Differ (1995) 0.89
Immunization in children with HIV seropositivity at birth: antibody response to polio vaccine and tetanus toxoid. AIDS (1992) 0.89
A peptide inhibiting the collagen binding function of integrin alpha2I domain. J Biol Chem (1999) 0.89
Metabolite profiles of the biocontrol yeast Pichia anomala J121 grown under oxygen limitation. Appl Microbiol Biotechnol (2003) 0.89
Localization of the alpha v subfamily of integrins and their putative ligands in synovial lining cell layer. J Rheumatol (1995) 0.89
Bacterial heat shock protein-60 increases epithelial cell proliferation through the ERK1/2 MAP kinases. Exp Cell Res (2001) 0.89
Serum tumour necrosis factor compared with C-reactive protein in the early assessment of severity of acute pancreatitis. Br J Surg (1995) 0.89
Identification of alpha6beta1 integrin positive cells in synovial lining layer as type B synoviocytes. J Rheumatol (2001) 0.89
Effects of homodimeric isoforms of platelet-derived growth factor (PDGF-AA and PDGF-BB) on wound healing in rat. J Surg Res (1992) 0.89
Morphologic alterations in cultured human synovial fibroblasts induced by blood mononuclear cells. Exp Cell Biol (1984) 0.88
Suppression of syndecan-1 expression in endothelial cells by tumor necrosis factor-alpha. J Biol Chem (1996) 0.88
Sodium phosphate is superior to polyethylene glycol in bowel cleansing and shortens the time it takes to visualize colon mucosa. Scand J Gastroenterol (2003) 0.88
The epidemiology and treatment patterns of postoperative adhesion induced intestinal obstruction in Varsinais-Suomi Hospital District. Scand J Surg (2004) 0.88
Platelet-derived growth factor isoforms PDGF-AA, -AB and -BB exert specific effects on collagen gene expression and mitotic activity of cultured human wound fibroblasts. Biochem Biophys Res Commun (1995) 0.88
Integrins alpha5beta1, alphavbeta1, and alphavbeta6 collaborate in squamous carcinoma cell spreading and migration on fibronectin. Exp Cell Res (2000) 0.88
Urinary bladder transitional cell carcinogenesis is associated with down-regulation of NF1 tumor suppressor gene in vivo and in vitro. Am J Pathol (1999) 0.88
National Italian Guidelines for caries prevention in 0 to 12 years-old children. Eur J Paediatr Dent (2007) 0.87
Fibronectin fragmentation induced by dental plaque and Bacteroides gingivalis. Scand J Dent Res (1987) 0.87
Pseudo-Gaucher plasma cells in the bone marrow of a patient with monoclonal gammopathy of undetermined significance. Haematologica (1998) 0.87
Measles virus enhances the expression of cellular immediate-early genes and DNA-binding of transcription factor AP-1 in lung epithelial A549 cells. Arch Virol (2002) 0.87
Anti-integrin antibodies induce type IV collagenase expression in keratinocytes. J Cell Physiol (1993) 0.86
PLA2 (group IIA phospholipase A2) as a prognostic determinant in stage II colorectal carcinoma. Ann Oncol (2009) 0.86
Antibody against human alpha 1 beta 1 integrin inhibits HeLa cell adhesion to laminin and to type I, IV, and V collagens. Biochem Biophys Res Commun (1995) 0.86
A chance of misdiagnosis between acute appendicitis and renal colic. Scand J Urol Nephrol (1996) 0.86
Effect of sucrose on collagen metabolism in keloid, hypertrophic scar, and granulation tissue fibroblast cultures. World J Surg (2001) 0.86
Enterovirus receptors and virus replication in human leukocytes. J Gen Virol (1999) 0.86
Effect of epidermal growth factor (EGF) on experimental granulation tissue. J Surg Res (1986) 0.85
Effect of epidermal growth factor (EGF) on blood flow and albumin extravasation in experimental granulation tissue. Acta Chir Scand (1986) 0.85
Altered integrin expression in rheumatoid synovial lining type B cells: in vitro cytokine regulation of alpha 1 beta 1, alpha 6 beta 1, and alpha v beta 5 integrins. J Rheumatol (1996) 0.85
Healing of meniscal tissue by cellular fibrin glue: an in vivo study. Knee Surg Sports Traumatol Arthrosc (2009) 0.85
Cortical myoclonus in Janz syndrome. Clin Neurophysiol (2001) 0.85
Expression of epithelial adhesion proteins and integrins in chronic inflammation. Am J Pathol (1995) 0.85
Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice. Diabetologia (2013) 0.84
Innervation of normal and hypertrophic human scars and experimental wounds in the rat. Ann Chir Gynaecol (2001) 0.84
A small-molecule inhibitor of integrin alpha2 beta1 introduces a new strategy for antithrombotic therapy. Thromb Haemost (2009) 0.84
Expression of cyclooxygenase-1 and -2 in urinary bladder carcinomas in vivo and in vitro and prostaglandin E2 synthesis in cultured bladder cancer cells. Pathology (2001) 0.84
The cleansing result of oral sodium phosphate is inversely correlated with time between the last administration and colonoscopy. Tech Coloproctol (2007) 0.84
Decline in anti-HAV prevalence in the Milan area between 1958 and 1992. Eur J Epidemiol (1994) 0.83
The cell adhesion domain of type XVII collagen promotes integrin-mediated cell spreading by a novel mechanism. J Biol Chem (2001) 0.83
Adherent cells from rheumatoid synovia: identity of HLA-DR positive stellate cells. Ann Rheum Dis (1987) 0.83
"RKKH" peptides from the snake venom metalloproteinase of Bothrops jararaca bind near the metal ion-dependent adhesion site of the human integrin alpha(2) I-domain. J Biol Chem (1999) 0.83
Mechanisms in TGF-beta action. Ciba Found Symp (1991) 0.83
Interferon-alpha inhibits cyclooxygenase-1 and stimulates cyclooxygenase-2 expression in bladder cancer cells in vitro. Urol Res (2001) 0.83
Interferon-alpha and interferon-gamma reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture. Biochim Biophys Acta (1988) 0.83