MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation.

PubWeight™: 1.44‹?› | Rank: Top 5%

🔗 View Article (PMID 9886240)

Published in J Leukoc Biol on January 01, 1999

Authors

W D Fairlie1, A G Moore, A R Bauskin, P K Russell, H P Zhang, S N Breit

Author Affiliations

1: Centre for Immunology, St Vincent's Hospital and University of New South Wales, Sydney, Australia.

Articles citing this

Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer. J Cell Physiol (2010) 1.81

Cell cycle arrest and apoptosis provoked by UV radiation-induced DNA damage are transcriptionally highly divergent responses. Nucleic Acids Res (2003) 1.34

Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: the Rancho Bernardo Study. Circulation (2011) 1.25

Growth differentiation factor 15 in erythroid health and disease. Curr Opin Hematol (2010) 1.21

Progressive postnatal motoneuron loss in mice lacking GDF-15. J Neurosci (2009) 1.20

Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway. Oncogene (2009) 1.19

Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer. Br J Cancer (2011) 1.16

Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 1.13

TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One (2013) 1.12

Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors. Proc Natl Acad Sci U S A (2006) 1.11

Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15. Int J Obes (Lond) (2015) 1.08

Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer. Br J Cancer (2010) 1.07

The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-beta superfamily member, acts as a quality control determinant for correctly folded MIC-1. EMBO J (2000) 1.05

GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective. J Diabetes Res (2015) 0.99

Macrophage-targeted photodynamic therapy. Int J Immunopathol Pharmacol (2004) 0.93

Regulation of GDF-15, a distant TGF-β superfamily member, in a mouse model of cerebral ischemia. Cell Tissue Res (2010) 0.91

Macrophage inhibitory cytokine-1 regulates melanoma vascular development. Am J Pathol (2010) 0.91

RNPC1, an RNA-binding protein and a p53 target, regulates macrophage inhibitory cytokine-1 (MIC-1) expression through mRNA stability. J Biol Chem (2013) 0.90

Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression. PLoS One (2012) 0.90

Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury. J Am Heart Assoc (2012) 0.89

DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines. Int J Cancer (2011) 0.89

Change of body weight and macrophage inhibitory cytokine-1 during chemotherapy in advanced gastric cancer: what is their clinical significance? PLoS One (2014) 0.85

Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study. PLoS One (2014) 0.85

Circulating and placental growth-differentiation factor 15 in preeclampsia and in pregnancy complicated by diabetes mellitus. Hypertension (2009) 0.84

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis. Cancer Med (2014) 0.84

Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53. Br J Pharmacol (2014) 0.83

Prolonged NF-κB activation by a macrophage inhibitory cytokine 1-linked signal in enteropathogenic Escherichia coli-infected epithelial cells. Infect Immun (2013) 0.79

Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI. PLoS One (2015) 0.79

The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis. Cancer Med (2015) 0.78

The association of growth differentiation factor-15 with left ventricular hypertrophy in hypertensive patients. PLoS One (2012) 0.78

Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels. Sci Rep (2016) 0.77

The relationship of serum macrophage inhibitory cytokine-1 levels with gray matter volumes in community-dwelling older individuals. PLoS One (2015) 0.77

Growth differentiation factor-15 and white matter hyperintensities in cognitive impairment and dementia. Medicine (Baltimore) (2016) 0.76

Assessment of selected cytokines, proteins, and growth factors in the peritoneal fluid of patients with ovarian cancer and benign gynecological conditions. Onco Targets Ther (2015) 0.76

MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma. Br J Cancer (2015) 0.76

The nuclear receptor REV-ERBα represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells. Physiol Rep (2016) 0.75

First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15. PLoS One (2017) 0.75

Effect of proline rich 15-deficiency on trophoblast viability and survival. PLoS One (2017) 0.75

GDF-15 predicts cardiovascular events in acute chest pain patients. PLoS One (2017) 0.75

GDF15 is a heart-derived hormone that regulates body growth. EMBO Mol Med (2017) 0.75

A novel serum based biomarker panel has complementary ability to preclude presence of early lung cancer for low dose CT (LDCT). Oncotarget (2017) 0.75

Articles by these authors

Tularemia as a biological weapon: medical and public health management. JAMA (2001) 13.23

The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA (2000) 12.26

Botulinum toxin as a biological weapon: medical and public health management. JAMA (2001) 9.18

Plague as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA (2000) 8.45

Smallpox as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA (1999) 7.96

Anthrax as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA (1999) 7.06

A plaque reduction test for dengue virus neutralizing antibodies. J Immunol (1967) 5.78

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci U S A (1997) 4.20

Flaviviridae. Intervirology (1985) 3.06

Radiation pneumonitis: a possible lymphocyte-mediated hypersensitivity reaction. Ann Intern Med (1993) 2.76

Isolation of a temperature-sensitive dengue-2 virus under conditions suitable for vaccine development. Infect Immun (1976) 2.67

The potential pathogenic role of complement in dengue hemorrhagic shock syndrome. N Engl J Med (1973) 2.64

Detection of additional antigenic determinants of hepatitis B antigen. J Immunol (1972) 2.57

Bunyaviridae. Intervirology (1980) 2.53

Dengue virus identification by the plaque reduction neutralization test. J Immunol (1967) 2.45

Antigenic characterization of two sindbis envelope glycoproteins separated by isoelectric focusing. Virology (1976) 2.32

Togaviridae. Intervirology (1985) 1.96

Immunization with live types 7 and 4 adenovirus vaccines. I. Safety, infectivity, antigenicity, and potency of adenovirus type 7 vaccine in humans. J Infect Dis (1971) 1.95

Hemorrhagic fever in Thailand; recent knowledge regarding etiology. Jpn J Med Sci Biol (1967) 1.94

Swine influenza A at Fort Dix, New Jersey (January-February 1976). IV. Summary and speculation. J Infect Dis (1977) 1.88

Interaction of Sindbis virus with liposomal model membranes. J Virol (1975) 1.85

Passive immunisation of children with bovine colostrum containing antibodies to human rotavirus. Lancet (1989) 1.84

Dengue-virus recovery by direct and delayed plaques in LLC-MK2 cells. Am J Trop Med Hyg (1968) 1.80

Replication of dengue-2 virus in cultured human lymphoblastoid cells and subpopulations of human peripheral leukocytes. J Immunol (1976) 1.79

Radioimmune precipitation of group A arboviruses. J Immunol (1972) 1.71

Immunoprecipitation analysis of soluble complement-fixing antigens of dengue viruses. J Immunol (1970) 1.69

Change involving a viral membrane glycoprotein during morphogenesis of group B arboviruses. Virology (1972) 1.69

Infection enhancement of dengue type 2 virus in the U-937 human monocyte cell line by antibodies to flavivirus cross-reactive determinants. Infect Immun (1982) 1.69

An insular outbreak of dengue hemorrhagic fever. II. Virologic and serologic studies. Am J Trop Med Hyg (1968) 1.68

Dengue-2 vaccine: preparation from a small-plaque virus clone. Infect Immun (1980) 1.67

Immunological and biophysical separation of dengue-2 antigens. J Virol (1971) 1.66

Anti-dengue immunoglobulins and serum beta 1 c-a globulin levels in dengue shock syndrome. J Immunol (1969) 1.64

The proteins of Japanese encephalitis virus. Virology (1971) 1.63

An analysis of fevers of unknown origin in American soldiers in Vietnam. Ann Intern Med (1967) 1.61

Evidence for two mechanisms of dengue virus infection of adherent human monocytes: trypsin-sensitive virus receptors and trypsin-resistant immune complex receptors. Infect Immun (1981) 1.58

Bunyaviruses and Bunyaviridae. Intervirology (1976) 1.58

Radiation and the lung: a reevaluation of the mechanisms mediating pulmonary injury. Int J Radiat Oncol Biol Phys (1995) 1.58

Virulence and immunogenicity of a temperature-sensitive dengue-2 virus in lower primates. Infect Immun (1977) 1.51

Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution. J Biol Chem (2001) 1.49

Antibody response in dengue and dengue hemorrhagic fever. Jpn J Med Sci Biol (1967) 1.47

Effect of passage history on dengue-2 virus replication in subpopulations of human leukocytes. Infect Immun (1979) 1.44

Molecular cloning and expression of a chloride ion channel of cell nuclei. J Biol Chem (1997) 1.41

Deadly competition between sibling bacterial colonies. Proc Natl Acad Sci U S A (2009) 1.40

Experimental infection of chimpanzees with dengue viruses. Am J Trop Med Hyg (1978) 1.39

Swine influenza A at Fort Dix, New Jersey (January-February 1976). I. Case finding and clinical study of cases. J Infect Dis (1977) 1.39

The role of alpha 1-antitrypsin deficiency in the pathogenesis of immune disorders. Clin Immunol Immunopathol (1985) 1.39

Swine influenza A at Fort Dix, New Jersey (January-February 1976). III. Extent of spread and duration of the outbreak. J Infect Dis (1977) 1.38

Partial purification and characterization of a dengue virus soluble complement-fixing antigen. J Immunol (1970) 1.37

Control of respiratory disease in recruits with types 4 and 7 adenovirus vaccines. Am J Epidemiol (1971) 1.36

Microplate reader-based quantitation of collagens. Anal Biochem (1992) 1.34

Sequential dengue virus infections in the white-handed gibbon (Hylobates lar). Am J Trop Med Hyg (1970) 1.33

Immunization with live types 7 and 4 adenovirus vaccines. II. Antibody response and protective effect against acute respiratory disease due to adenovirus type 7. J Infect Dis (1971) 1.33

Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain. Nature (1988) 1.32

Antigenic components of group A arbovirus virions. J Virol (1973) 1.30

Dengue virions and antigens in brain and serum of infected mice. J Virol (1970) 1.30

In vitro phosphorylation and purification of a nonstructural protein of bluetongue virus with affinity for single-stranded RNA. J Virol (1987) 1.29

Human immunoglobulin specificity after group B arbovirus infections. Infect Immun (1972) 1.29

Dengue-2 vaccine: virological, immunological, and clinical responses of six yellow fever-immune recipients. Infect Immun (1981) 1.28

Dengue-2 vaccine: viremia and immune responses in rhesus monkeys. Infect Immun (1980) 1.27

Dengue 2 vaccine: dose response in volunteers in relation to yellow fever immune status. J Infect Dis (1983) 1.27

Cytological localization of Dengue-2 antigens: an immunological study with ultrastructural correlation. Infect Immun (1973) 1.26

Recovery of dengue viruses from patients during epidemics in Puerto Rico and East Pakistan. Am J Trop Med Hyg (1966) 1.25

RNA fingerprinting as a method for distinguishing dengue 1 virus strains. Am J Trop Med Hyg (1983) 1.25

Togaviridae. Intervirology (1978) 1.24

The meaning of the point of maximum oscillations in cuff pressure in the indirect measurement of blood pressure. 1. Cardiovasc Res Cent Bull (1970) 1.23

Comparison of dengue-2 and dengue-3 virus strains by neutralization tests and identification of a subtype of dengue-3. Am J Trop Med Hyg (1972) 1.23

PAH extraction and estimation of plasma flow in diseased human kidneys. Am J Physiol (1991) 1.23

Assay of arbovirus neutralizing antibody by micro methods. Trans R Soc Trop Med Hyg (1969) 1.21

Enteric immunization with live adenovirus type 21 vaccine. II. Systemic and local immune responses following immunization. Infect Immun (1972) 1.21

Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured rat brain. J Comp Neurol (2001) 1.20

Dengue virus type 2 vaccine: reactogenicity and immunogenicity in soldiers. J Infect Dis (1984) 1.20

Electrical dose for ventricular defibrillation of large and small animals using precordial electrodes. J Clin Invest (1974) 1.20

Enteritis and gastritis in young asymptomatic Pakistani men. Am J Dig Dis (1966) 1.19

Antibody-based approach to high-volume genotyping for MIC-1 polymorphism. Biotechniques (2002) 1.18

More on subprofessionals for libraries. N Engl J Med (1973) 1.18

Swine influenza A at Fort Dix, New Jersey (January-February 1976). II. Transmission and morbidity in units with cases. J Infect Dis (1977) 1.17

Detection of dengue cell-surface antigens by peroxidase-labeled antibodies and immune cytolysis. Infect Immun (1974) 1.16

Comparison of direct and indirect arterial pressure measurements in hospitalized patients. Aust N Z J Med (1974) 1.15

Lack of attenuation of a candidate dengue 1 vaccine (45AZ5) in human volunteers. Am J Trop Med Hyg (1987) 1.13

The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. J Clin Endocrinol Metab (2000) 1.12

Selection of attenuated dengue 4 viruses by serial passage in primary kidney cells. V. Human response to immunization with a candidate vaccine prepared in fetal rhesus lung cells. Am J Trop Med Hyg (1984) 1.11

Variables in the isolation and culture of human monocytes that are of particular relevance to studies of HIV. J Leukoc Biol (1994) 1.11

Dengue-2 vaccine: oral infection, transmission, and lack of evidence for reversion in the mosquito, Aedes aegypti. Am J Trop Med Hyg (1982) 1.10

Recurrence of epidemic dengue hemorrhagic fever in an insular setting. Am J Trop Med Hyg (1969) 1.09

The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle. J Physiol (2000) 1.09

Interaction of immune and connective tissue cells: I. The effect of lymphokines and monokines on fibroblast growth. J Leukoc Biol (1990) 1.09

An insular outbreak of dengue hemorrhagic fever. I. Epidemiologic observations. Am J Trop Med Hyg (1968) 1.08

Paenibacillus dendritiformis bacterial colony growth depends on surfactant but not on bacterial motion. J Bacteriol (2009) 1.07

Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer. Br J Cancer (2010) 1.07

The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-beta superfamily member, acts as a quality control determinant for correctly folded MIC-1. EMBO J (2000) 1.05