Published in Semin Cell Dev Biol on December 01, 1998
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev (2003) 4.89
Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci U S A (1999) 3.53
A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish. EMBO Rep (2002) 3.53
Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev (2005) 3.27
Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling. J Cell Biol (1999) 2.39
Delta-like 4 is indispensable in thymic environment specific for T cell development. J Exp Med (2008) 2.02
Development and differentiation of the intestinal epithelium. Cell Mol Life Sci (2003) 1.80
RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. Proc Natl Acad Sci U S A (2007) 1.78
Neural differentiation of embryonic stem cells in vitro: a road map to neurogenesis in the embryo. PLoS One (2009) 1.61
Notch signaling in the development of the inner ear: lessons from Drosophila. Proc Natl Acad Sci U S A (2000) 1.61
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev (2006) 1.60
Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct. PLoS Genet (2007) 1.54
Role of STRAP in regulating GSK3β function and Notch3 stabilization. Cell Cycle (2011) 1.54
Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage. Proc Natl Acad Sci U S A (1999) 1.54
Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles. J Neurosci (2011) 1.53
Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta (2010) 1.50
Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas. Dev Biol (2009) 1.46
Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung. J Biol Chem (2008) 1.40
Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. Proc Natl Acad Sci U S A (2010) 1.37
Notch signaling, the segmentation clock, and the patterning of vertebrate somites. J Biol (2009) 1.34
MAZe: a tool for mosaic analysis of gene function in zebrafish. Nat Methods (2010) 1.25
Notch regulation of progenitor cell behavior in quiescent and regenerating auditory epithelium of mature birds. Dev Biol (2008) 1.24
The challenge of hair cell regeneration. Exp Biol Med (Maywood) (2010) 1.14
Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. Dev Biol (2011) 1.11
Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion. Development (2010) 1.10
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling. Development (2011) 1.08
Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol (2008) 1.07
Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Dev Cell (2014) 1.06
FGF-dependent Notch signaling maintains the spinal cord stem zone. Genes Dev (2005) 0.99
The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell-cell signalling. J R Soc Interface (2010) 0.99
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med (2014) 0.99
Notch signaling in cardiac development and disease. Pediatr Cardiol (2009) 0.98
Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells. Nat Commun (2015) 0.97
JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotype. J Med Genet (2000) 0.96
Recent advances in hair cell regeneration research. Curr Opin Otolaryngol Head Neck Surg (2008) 0.94
From segment to somite: segmentation to epithelialization analyzed within quantitative frameworks. Dev Dyn (2007) 0.92
Micropatterned multicolor dynamically adhesive substrates to control cell adhesion and multicellular organization. Langmuir (2014) 0.92
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. Elife (2014) 0.92
Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions. PLoS Biol (2013) 0.91
Jagged 1 is necessary for normal mouse lens formation. Dev Biol (2009) 0.91
NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol (2016) 0.91
Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype. Proc Natl Acad Sci U S A (2015) 0.91
Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear. Dev Dyn (2006) 0.91
A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cells. PLoS One (2007) 0.90
Synthetic morphology: prospects for engineered, self-constructing anatomies. J Anat (2008) 0.90
Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer. Cancer Growth Metastasis (2015) 0.90
A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?". Hear Res (2013) 0.89
Beyond angiogenesis blockade: targeted therapy for advanced cervical cancer. J Gynecol Oncol (2014) 0.89
On the role of lateral stabilization during early patterning in the pancreas. J R Soc Interface (2013) 0.89
Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease. EMBO Rep (2015) 0.89
Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures. Cancer Biol Ther (2013) 0.88
Oscillations and patterns in spatially discrete models for developmental intercellular signalling. J Math Biol (2003) 0.88
Lunatic fringe promotes the lateral inhibition of neurogenesis. Development (2009) 0.88
Transdifferentiation of pancreatic cells by loss of contact-mediated signaling. BMC Syst Biol (2013) 0.86
Identification of a novel activation domain in the Notch-responsive transcription factor CSL. Nucleic Acids Res (2001) 0.86
How to innervate a simple gut: familiar themes and unique aspects in the formation of the insect enteric nervous system. Dev Dyn (2007) 0.84
Sensory neuron differentiation is regulated by notch signaling in the trigeminal placode. Dev Biol (2010) 0.83
Complex regulation of HSC emergence by the Notch signaling pathway. Dev Biol (2015) 0.82
Limbal stem cells, a review of their identification and culture for clinical use. Cytotechnology (2007) 0.82
γ-Secretase-regulated mechanisms similar to notch signaling may play a role in signaling events, including APP signaling, which leads to Alzheimer's disease. Cell Mol Neurobiol (2011) 0.81
Thymocyte apoptosis. J Clin Immunol (1999) 0.81
prdm1a and olig4 act downstream of Notch signaling to regulate cell fate at the neural plate border. Dev Biol (2011) 0.81
Where hearing starts: the development of the mammalian cochlea. J Anat (2015) 0.79
Interaction between gastric cancer stem cells and the tumor microenvironment. J Gastroenterol (2014) 0.78
Prognostic values of four Notch receptor mRNA expression in gastric cancer. Sci Rep (2016) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti. Dev Biol (2016) 0.77
The role of her4 in inner ear development and its relationship with proneural genes and Notch signalling. PLoS One (2014) 0.77
Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction. Curr Opin Struct Biol (2016) 0.77
Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo. PLoS Genet (2015) 0.76
Notch-Mediated Cell Adhesion. Biology (Basel) (2016) 0.76
Notch signaling pathway is activated in motoneurons of spinal muscular atrophy. Int J Mol Sci (2013) 0.76
Cancer metastasis as disrupted developmental phenotype. Curr Genomics (2008) 0.75
A spectrum of modularity in multi-functional gene circuits. Mol Syst Biol (2017) 0.75
Developmental transcriptome analysis and identification of genes involved in formation of intestinal air-breathing function of Dojo loach, Misgurnus anguillicaudatus. Sci Rep (2016) 0.75
Metabolic control of the cell cycle. Cell Cycle (2015) 0.75
Delta-Notch signalling in segmentation. Arthropod Struct Dev (2016) 0.75
Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer. Oncotarget (2017) 0.75
Unexpected evolutionarily conserved rapid effects of viral infection on oxytocin receptor and TGF-β/pSmad3. Skelet Muscle (2017) 0.75
Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog (2016) 0.75
Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. Front Cell Neurosci (2015) 0.75