Published in J Membr Biol on January 15, 1999
Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain. Proc Natl Acad Sci U S A (1999) 1.75
Interactions of fluorinated surfactants with diphtheria toxin T-domain: testing new media for studies of membrane proteins. Biophys J (2008) 1.20
The N-terminal domain of Bcl-xL reversibly binds membranes in a pH-dependent manner. Biochemistry (2006) 1.00
Oligomerization of membrane-bound diphtheria toxin (CRM197) facilitates a transition to the open form and deep insertion. Biophys J (2007) 0.85
Folding of diphtheria toxin T-domain in the presence of amphipols and fluorinated surfactants: Toward thermodynamic measurements of membrane protein folding. Biochim Biophys Acta (2011) 0.77
Identification of the cellular receptor for anthrax toxin. Nature (2001) 8.78
Diphtheria toxin: mode of action and structure. Bacteriol Rev (1975) 7.47
Crystal structure of the anthrax toxin protective antigen. Nature (1997) 6.63
Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments. J Biol Chem (1971) 5.51
Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria. J Membr Biol (1976) 5.01
The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport. J Membr Biol (1981) 4.79
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet (1996) 4.77
Enzymatically active peptide from the adenosine diphosphate-ribosylating toxin of Pseudomonas aeruginosa. Infect Immun (1977) 4.46
Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem (1994) 4.40
The water and nonelectrolyte permeability induced in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B. J Gen Physiol (1970) 4.28
Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes. Proc Natl Acad Sci U S A (1981) 4.28
BAX is required for neuronal death after trophic factor deprivation and during development. Neuron (1996) 4.02
Colicin K acts by forming voltage-dependent channels in phospholipid bilayer membranes. Nature (1978) 3.81
The crystal structure of diphtheria toxin. Nature (1992) 3.80
Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta. Proc Natl Acad Sci U S A (1983) 3.79
Crystal structure of the anthrax lethal factor. Nature (2001) 3.75
Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers. Proc Natl Acad Sci U S A (1989) 3.54
Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution. Proc Natl Acad Sci U S A (1986) 3.41
On the role of macrophages in anthrax. Proc Natl Acad Sci U S A (1993) 3.34
Anthrax protective antigen: prepore-to-pore conversion. Biochemistry (1999) 3.28
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule. J Biol Chem (1971) 3.27
Identification of residues lining the anthrax protective antigen channel. Biochemistry (1998) 3.18
Brachial amyotrophic diplegia: a slowly progressive motor neuron disorder. Neurology (1999) 3.17
Equivalent Circuits as Related to Ionic Systems. Biophys J (1963) 3.08
The ion permeability induced in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B. J Gen Physiol (1970) 3.03
Crystal structure of the zeta isoform of the 14-3-3 protein. Nature (1995) 2.98
Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus. Mol Microbiol (1995) 2.96
Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. J Mol Biol (1967) 2.95
Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition. J Biol Chem (1979) 2.93
Affinity filters, a new approach to the isolation of tox mutants of Vibrio cholerae. Proc Natl Acad Sci U S A (1978) 2.89
Fusion of phospholipid vesicles with planar phospholipid bilayer membranes. II. Incorporation of a vesicular membrane marker into the planar membrane. J Gen Physiol (1980) 2.86
Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax. Science (2001) 2.84
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes. Proc Natl Acad Sci U S A (1985) 2.80
Characterization of membrane translocation by anthrax protective antigen. Biochemistry (1998) 2.75
Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science (1994) 2.74
Interaction of ions and water in gramicidin A channels: streaming potentials across lipid bilayer membranes. J Gen Physiol (1978) 2.73
Effect of phloretin on the permeability of thin lipid membranes. J Gen Physiol (1976) 2.72
Water and nonelectrolyte permeability of lipid bilayer membranes. J Gen Physiol (1976) 2.68
Designing a polyvalent inhibitor of anthrax toxin. Nat Biotechnol (2001) 2.67
Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc Natl Acad Sci U S A (1995) 2.57
Simple method for purifying choleragenoid, the natural toxoid of Vibrio cholerae. Infect Immun (1977) 2.56
Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide. J Biol Chem (1974) 2.55
The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family. Proc Natl Acad Sci U S A (1993) 2.50
Effect of cholesterol on the water permeability of thin lipid membranes. Nature (1967) 2.45
Osmotic swelling of phospholipid vesicles causes them to fuse with a planar phospholipid bilayer membrane. Science (1982) 2.43
Water permeability of thin lipid membranes. J Gen Physiol (1967) 2.38
Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I. Proc Natl Acad Sci U S A (1988) 2.38
PTEN: a new guardian of the genome. Oncogene (2008) 2.37
Identification of a translocated protein segment in a voltage-dependent channel. Nature (1994) 2.36
Membrane biochemistry. Annu Rev Biochem (1968) 2.33
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J Neurosci (2000) 2.27
pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. J Exp Med (1997) 2.26
Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B. Membranes (1973) 2.22
The acquired immunodeficiency syndrome and Mycobacterium avium-intracellulare bacteremia in a patient with hemophilia. Ann Intern Med (1983) 2.21
Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription. Mol Cell Biol (1996) 2.19
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family. Science (1994) 2.18
Purification of cholera toxin and its subunits: new methods of preparation and the use of hypertoxinogenic mutants. Infect Immun (1978) 2.16
Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells. Infect Immun (1991) 2.12
Expression of enzymic activity by exotoxin A from Pseudomonas aeruginosa. Infect Immun (1980) 2.11
Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol (1994) 2.00
The effect of surface charge on the voltage-dependent conductance induced in thin lipid membranes by monazomycin. J Gen Physiol (1972) 1.99
Fusion of phospholipid vesicles with planar phospholipid bilayer membranes. I. Discharge of vesicular contents across the planar membrane. J Gen Physiol (1980) 1.97
Water permeability of gramicidin A-treated lipid bilayer membranes. J Gen Physiol (1978) 1.97
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes Dev (1994) 1.97
Osmotic swelling of vesicles: its role in the fusion of vesicles with planar phospholipid bilayer membranes and its possible role in exocytosis. Annu Rev Physiol (1986) 1.93
Point mutations in anthrax protective antigen that block translocation. J Biol Chem (2000) 1.92
Interleukin-10 in the brain. Crit Rev Immunol (2001) 1.89
Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization. Cell Microbiol (2000) 1.87
Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells. Mol Biol Cell (1992) 1.86
NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD. Proc Natl Acad Sci U S A (1984) 1.83
Major transmembrane movement associated with colicin Ia channel gating. J Gen Physiol (1996) 1.82
pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen. Mol Microbiol (1993) 1.81
Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain. Proc Natl Acad Sci U S A (1999) 1.75
Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity. J Bacteriol (1987) 1.75
Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin. J Biol Chem (1987) 1.75
Amino-acid sequence of fragment A, an enzymically active fragment from diphtheria toxin. Proc Natl Acad Sci U S A (1976) 1.74
Parameters affecting the fusion of unilamellar phospholipid vesicles with planar bilayer membranes. J Cell Biol (1984) 1.71
Diphtheria toxin. Effect of substituting aspartic acid for glutamic acid 148 on ADP-ribosyltransferase activity. J Biol Chem (1985) 1.70
Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance. J Gen Physiol (1990) 1.68
Voltage-dependent conductance induced in thin lipid membranes by monazomycin. J Gen Physiol (1972) 1.67
Assignment of a second Charcot-Marie-Tooth type II locus to chromosome 3q. Am J Hum Genet (1995) 1.66
The nonelectrolyte permeability of planar lipid bilayer membranes. J Gen Physiol (1980) 1.66
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study. Science (1996) 1.64
Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles. Proc Natl Acad Sci U S A (2010) 1.62
Fenoprofen nephropathy: lipoid nephrosis and interstitial nephritis. A possible T-lymphocyte disorder. Am J Med (1982) 1.62
Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin. J Bacteriol (2001) 1.62
A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen. Biochemistry (2000) 1.61
Role of macrophage oxidative burst in the action of anthrax lethal toxin. Mol Med (1994) 1.60
Exotoxin A of Pseudomonas aeruginosa: active, cloned toxin is secreted into the periplasmic space of Escherichia coli. J Bacteriol (1987) 1.58
Structure and function of anthrax toxin. Curr Top Microbiol Immunol (2002) 1.56
Membrane channels and conductance. Discussion paper. Ann N Y Acad Sci (1975) 1.55
Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells. Proc Natl Acad Sci U S A (1980) 1.54
Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Single-channel analysis. J Gen Physiol (1990) 1.52
Pores formed in lipid bilayer membranes by nystatin, Differences in its one-sided and two-sided action. J Gen Physiol (1975) 1.52