Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs.

PubWeight™: 2.76‹?› | Rank: Top 1%

🔗 View Article (PMID 9920228)

Published in J Am Geriatr Soc on January 01, 1999

Authors

R M Leipzig1, R G Cumming, M E Tinetti

Author Affiliations

1: Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York 10029-6574, USA.

Articles citing this

Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults. JAMA Intern Med (2014) 4.22

Objective light-intensity physical activity associations with rated health in older adults. Am J Epidemiol (2010) 3.22

Intensive blood pressure control, falls, and fractures in patients with type 2 diabetes: the ACCORD trial. J Gen Intern Med (2014) 2.20

Cause or Effect? Selective Serotonin Reuptake Inhibitors and Falls in Older Adults: A Systematic Review. Am J Geriatr Psychiatry (2014) 2.08

Meta-analyses of adverse effects data derived from randomised controlled trials as compared to observational studies: methodological overview. PLoS Med (2011) 2.06

Polypharmacy and falls in the middle age and elderly population. Br J Clin Pharmacol (2006) 2.02

How ready is general practice to improve quality in chronic kidney disease? A diagnostic analysis. Br J Gen Pract (2010) 1.90

Opioid analgesics and the risk of fractures in older adults with arthritis. J Am Geriatr Soc (2011) 1.76

The association of nocturia with incident falls in an elderly community-dwelling cohort. Int J Clin Pract (2010) 1.69

Number and dosage of central nervous system medications on recurrent falls in community elders: the Health, Aging and Body Composition study. J Gerontol A Biol Sci Med Sci (2009) 1.64

Inappropriate medication use and risk of falls--a prospective study in a large community-dwelling elderly cohort. BMC Geriatr (2009) 1.50

Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol (2006) 1.48

Evaluation of risk of falls and orthostatic hypotension in older, long-term topical beta-blocker users. Graefes Arch Clin Exp Ophthalmol (2009) 1.40

[Prevention of adverse drug reactions in older patients]. Z Gerontol Geriatr (2007) 1.27

Polypharmacy in older adults with cancer. Oncologist (2010) 1.23

The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP in chronic kidney disease (CKD) in primary care. Implement Sci (2009) 1.22

Fall-related injuries in a nursing home setting: is polypharmacy a risk factor? BMC Health Serv Res (2009) 1.19

Falls in patients with chronic obstructive pulmonary disease: a call for further research. Respir Med (2009) 1.18

Falls: epidemiology, pathophysiology, and relationship to fracture. Curr Osteoporos Rep (2008) 1.16

Multidisciplinary medication review in nursing home residents: what are the most significant drug-related problems? The Bergen District Nursing Home (BEDNURS) study. Qual Saf Health Care (2003) 1.15

Diuretic initiation and the acute risk of hip fracture. Osteoporos Int (2012) 1.14

Chronic disease and falls in community-dwelling Canadians over 65 years old: a population-based study exploring associations with number and pattern of chronic conditions. BMC Geriatr (2014) 1.14

Falls in the community-dwelling older adult: a review for primary-care providers. Clin Interv Aging (2007) 1.12

Risk factors in falls among the elderly according to extrinsic and intrinsic precipitating causes. Eur J Epidemiol (2000) 1.10

Prevention of falls and fall-related injuries in community-dwelling seniors: an evidence-based analysis. Ont Health Technol Assess Ser (2008) 1.10

High yield research opportunities in geriatric emergency medicine: prehospital care, delirium, adverse drug events, and falls. J Gerontol A Biol Sci Med Sci (2011) 1.08

Antidepressant use, depressive symptoms, and incident frailty in women aged 65 and older from the Women's Health Initiative Observational Study. J Am Geriatr Soc (2012) 1.07

Routine deprescribing of chronic medications to combat polypharmacy. Ther Adv Drug Saf (2015) 1.04

Frequency and risk factors of potentially inappropriate medication use in a community-dwelling elderly population: results from the 3C Study. Eur J Clin Pharmacol (2004) 1.03

Systematic review of methods used in meta-analyses where a primary outcome is an adverse or unintended event. BMC Med Res Methodol (2012) 1.01

Loop diuretic use and rates of hip bone loss and risk of falls and fractures in older women. J Am Geriatr Soc (2009) 0.98

Community-based health efforts for the prevention of falls in the elderly. Clin Interv Aging (2010) 0.98

Angiotensin-converting enzyme inhibitor and statin use and incident mobility limitation in community-dwelling older adults: the Health, Aging and Body Composition study. J Am Geriatr Soc (2011) 0.98

Polypharmacy and potentially inappropriate medication use in older adults with cancer undergoing chemotherapy: effect on chemotherapy-related toxicity and hospitalization during treatment. J Am Geriatr Soc (2014) 0.97

Medication use as a risk factor for inpatient falls in an acute care hospital: a case-crossover study. Br J Clin Pharmacol (2010) 0.96

Risk factors for falls with severe fracture in elderly people living in a middle-income country: a case control study. BMC Geriatr (2008) 0.95

Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci (2010) 0.94

Poor adherence to medications may be associated with falls. J Gerontol A Biol Sci Med Sci (2010) 0.93

Accelerometer-based physical activity in a large observational cohort--study protocol and design of the activity and function of the elderly in Ulm (ActiFE Ulm) study. BMC Geriatr (2010) 0.93

Central nervous system medication use and incident mobility limitation in community elders: the Health, Aging, and Body Composition study. Pharmacoepidemiol Drug Saf (2009) 0.92

Is use of fall risk-increasing drugs in an elderly population associated with an increased risk of hip fracture, after adjustment for multimorbidity level: a cohort study. BMC Geriatr (2014) 0.91

Impact of a medication therapy management intervention targeting medications associated with falling: Results of a pilot study. J Am Pharm Assoc (2003) (2016) 0.91

Association between multi-dose drug dispensing and drug treatment changes. Eur J Clin Pharmacol (2012) 0.90

Medications associated with falls in older people: systematic review of publications from a recent 5-year period. Eur J Clin Pharmacol (2015) 0.89

Cognitive function as a prospective predictor of falls. J Gerontol B Psychol Sci Soc Sci (2012) 0.87

National outpatient medication profiling: medications associated with outpatient fractures in community-dwelling elderly veterans. Br J Clin Pharmacol (2006) 0.87

FRAT-up, a Web-based fall-risk assessment tool for elderly people living in the community. J Med Internet Res (2015) 0.86

Dose-response relationship between selective serotonin re-uptake inhibitors and injurious falls: a study in nursing home residents with dementia. Br J Clin Pharmacol (2012) 0.85

Hyponatremia and hypokalemia as risk factors for falls. Eur J Clin Nutr (2014) 0.85

What is the evidence to support the use of therapeutic gardens for the elderly? Psychiatry Investig (2012) 0.84

Medications prescribed and occurrence of falls in general medicine inpatients. Can J Hosp Pharm (2011) 0.84

Geriatric conditions in heart failure. Curr Cardiovasc Risk Rep (2012) 0.84

Falls risk among a very old home-dwelling population. Scand J Prim Health Care (2009) 0.83

The fall descriptions and health characteristics of older adults with hip fracture: a mixed methods study. BMC Geriatr (2015) 0.83

The Development of a Community-Based, Pharmacist-Provided Falls Prevention MTM Intervention for Older Adults: Relationship Building, Methods, and Rationale. Inov Pharm (2014) 0.82

Risk of hip fracture among older people using antihypertensive drugs: a nationwide cohort study. BMC Geriatr (2015) 0.82

Comparison of pooled risk estimates for adverse effects from different observational study designs: methodological overview. PLoS One (2013) 0.81

Simple balance and mobility tests can assess falls risk when cognition is impaired. Geriatr Nurs (2008) 0.81

[Benzodiazepines in geriatrics]. Z Gerontol Geriatr (2013) 0.80

Expert consensus panel guidelines on geriatric assessment in oncology. Eur J Cancer Care (Engl) (2015) 0.80

Effect of polypharmacy and potentially inappropriate medications on treatment and posttreatment courses in elderly patients with head and neck cancer. J Cancer Res Clin Oncol (2016) 0.80

Blood pressure and falls in community-dwelling people aged 60 years and older in the VHM&PP cohort. BMC Geriatr (2013) 0.79

Medication safety in residential aged-care facilities: a perspective. Ther Adv Drug Saf (2010) 0.79

Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes. J Bone Miner Metab (2012) 0.79

A dietary supplement to improve the quality of sleep: a randomized placebo controlled trial. BMC Complement Altern Med (2010) 0.79

Association between loop diuretic use and fracture risk. Osteoporos Int (2014) 0.79

Pharmacological treatment in Parkinson's disease: Effects on gait. Parkinsonism Relat Disord (2016) 0.79

Whole body vibration for older persons: an open randomized, multicentre, parallel, clinical trial. BMC Geriatr (2011) 0.78

[Cost] effectiveness of withdrawal of fall-risk increasing drugs versus conservative treatment in older fallers: design of a multicenter randomized controlled trial (IMPROveFALL-study). BMC Geriatr (2011) 0.78

Understanding approaches to balance assessment in physical therapy practice for elderly inpatients of a rehabilitation hospital. Physiother Can (2014) 0.77

Risk of hip/femur fractures during the initiation period of α-adrenoceptor blocker therapy among elderly males: a self-controlled case series study. Br J Clin Pharmacol (2015) 0.77

Drug-related falls in older patients: implicated drugs, consequences, and possible prevention strategies. Ther Adv Drug Saf (2013) 0.77

Danish register-based study on the association between specific cardiovascular drugs and fragility fractures. BMJ Open (2015) 0.76

Drug-induced falls in older persons: is there a role for therapeutic drug monitoring? Ther Adv Drug Saf (2016) 0.76

Falls among middle-aged women in the Women's Interagency HIV Study. Antivir Ther (2016) 0.76

The efficacy of fall-risk-increasing drug (FRID) withdrawal for the prevention of falls and fall-related complications: protocol for a systematic review and meta-analysis. Syst Rev (2017) 0.75

Community pneumonia--more help is needed to diagnose and assess severity. Br J Gen Pract (2002) 0.75

Calcaneal quantitative ultrasound and phalangeal radiographic absorptiometry alone or in combination in a triage approach for assessment of osteoporosis: a study of older women with a high prevalence of falls. BMC Geriatr (2014) 0.75

Description of spatio-temporal gait parameters in elderly people and their association with history of falls: results of the population-based cross-sectional KORA-Age study. BMC Geriatr (2015) 0.75

Risk factors of falls in inpatients and their practical use in identifying high-risk persons at admission: Fukushima Medical University Hospital cohort study. BMJ Open (2014) 0.75

A multicenter, case-control study of the effects of antihypertensive therapy on orthostatic hypotension, postprandial hypotension, and falls in octo- and nonagenarians in residential care facilities. Curr Ther Res Clin Exp (2003) 0.75

Use of Fall-Risk Inducing Drugs in Patients Using Anti-Parkinson Drugs (APD): A Swedish Register-Based Study. PLoS One (2016) 0.75

Risk of falls associated with antiepileptic drug use in ambulatory elderly populations: A systematic review. Can Pharm J (Ott) (2017) 0.75

Predicting Falls and When to Intervene in Older People: A Multilevel Logistical Regression Model and Cost Analysis. PLoS One (2016) 0.75

Evidence-based guidelines for fall prevention in Korea. Korean J Intern Med (2017) 0.75

THE RELATIONSHIP OF MEMORY, REASONING, AND SPEED OF PROCESSING ON FALLING AMONG OLDER ADULTS. Phys Occup Ther Geriatr (2008) 0.75

Cost-utility of medication withdrawal in older fallers: results from the improving medication prescribing to reduce risk of FALLs (IMPROveFALL) trial. BMC Geriatr (2016) 0.75

Medications and Patient Characteristics Associated With Falling in the Hospital. J Patient Saf (2015) 0.75

[Insomnia and increased use of sleep medication among seniors: problems and alternative treatment]. Can Fam Physician (2006) 0.75

Summary of scientific evidence. Occas Pap R Coll Gen Pract (2002) 0.75

Development and Evaluation of an Online Fall-Risk Questionnaire for Nonfrail Community-Dwelling Elderly Persons: A Pilot Study. Curr Gerontol Geriatr Res (2016) 0.75

A practical approach to the pharmacological management of hypertension in older people. Ther Adv Drug Saf (2016) 0.75

A wake up call for primary care. Br J Gen Pract (2002) 0.75

Analgesic Medicine Utilization in Older People in New Zealand from 2005 to 2013. Drugs Real World Outcomes (2015) 0.75

Identifying characteristics and outcomes that are associated with fall-related fatalities: multi-year retrospective summary of fall deaths in older adults from 2005-2012. Inj Epidemiol (2017) 0.75

Management of Gait Changes and Fall Risk in MCI and Dementia. Curr Treat Options Neurol (2017) 0.75

Articles by these authors

Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc (1986) 8.28

Interventions for preventing falls in elderly people. Cochrane Database Syst Rev (2003) 7.05

Fall risk index for elderly patients based on number of chronic disabilities. Am J Med (1986) 4.53

Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc (1999) 4.35

The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques. JAMA (1995) 3.94

Hip protectors in aged-care facilities: a randomized trial of use by individual higher-risk residents. Age Ageing (2001) 3.33

How best to fix a broken hip. Fractured Neck of Femur Health Outcomes Project Team. Med J Aust (1999) 3.25

Interventions for preventing falls in elderly people. Cochrane Database Syst Rev (2001) 3.06

A predictive model for delirium in hospitalized elderly medical patients based on admission characteristics. Ann Intern Med (1993) 3.01

Predicting changes in physical performance in a high-functioning elderly cohort: MacArthur studies of successful aging. J Gerontol (1994) 2.95

Driving cessation and increased depressive symptoms: prospective evidence from the New Haven EPESE. Established Populations for Epidemiologic Studies of the Elderly. J Am Geriatr Soc (1997) 2.93

Mortality and morbidity after hip fracture: can evidence based clinical pathways make a difference? J Rheumatol (2000) 2.89

Quality of life related to fear of falling and hip fracture in older women: a time trade off study. BMJ (2000) 2.79

Difficulty and dependence: two components of the disability continuum among community-living older persons. Ann Intern Med (1998) 2.68

Predictors of automobile crashes and moving violations among elderly drivers. Ann Intern Med (1994) 2.63

Assessing risk for the onset of functional dependence among older adults: the role of physical performance. J Am Geriatr Soc (1995) 2.62

Visual impairment and falls in older adults: the Blue Mountains Eye Study. J Am Geriatr Soc (1998) 2.51

A predictive index for functional decline in hospitalized elderly medical patients. J Gen Intern Med (1993) 2.34

A simple procedure for general screening for functional disability in elderly patients. Ann Intern Med (1990) 2.32

Functional disability and health care expenditures for older persons. Arch Intern Med (2001) 2.23

Hip protectors improve falls self-efficacy. Age Ageing (2000) 2.22

Falls in community-dwelling older persons. J Am Geriatr Soc (1995) 2.16

Users' guides to the medical literature: XVII. How to use guidelines and recommendations about screening. Evidence-Based Medicine Working Group. JAMA (1999) 1.96

Vision screening for frail older people: a randomised trial. Br J Ophthalmol (2008) 1.93

Development of the common data base for the FICSIT trials. J Am Geriatr Soc (1993) 1.89

The cost-effectiveness of a multifactorial targeted prevention program for falls among community elderly persons. Med Care (1996) 1.89

Diabetes and risk of fracture: The Blue Mountains Eye Study. Diabetes Care (2001) 1.84

Behavioral and psychosocial predictors of physical performance: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci (1995) 1.81

Prevalence of cataract in Australia: the Blue Mountains eye study. Ophthalmology (1997) 1.79

Health care utilization and costs in a Medicare population by fall status. Med Care (1998) 1.76

Development of a test battery to identify older drivers at risk for self-reported adverse driving events. J Am Geriatr Soc (1998) 1.74

Self-efficacy, physical decline, and change in functioning in community-living elders: a prospective study. J Gerontol B Psychol Sci Soc Sci (1996) 1.71

Impact of visual impairment on use of community support services by elderly persons: the Blue Mountains Eye Study. Invest Ophthalmol Vis Sci (1999) 1.70

Systematic review of randomized trials of the effect of exercise on bone mass in pre- and postmenopausal women. Calcif Tissue Int (2000) 1.66

Validation and use of performance measures of functioning in a non-disabled older population: MacArthur studies of successful aging. Aging (Milano) (1994) 1.66

Incidence of nursing home placement in a defined community. Med J Aust (2001) 1.65

Factors associated with serious injury during falls by ambulatory nursing home residents. J Am Geriatr Soc (1987) 1.64

Effects of cataract type and location on visual function: the Blue Mountains Eye Study. Eye (Lond) (2004) 1.62

Inhaled corticosteroids, family history, and risk of glaucoma. Ophthalmology (1999) 1.59

Mismatches between the home environment and physical capabilities among community-living older persons. J Am Geriatr Soc (1999) 1.56

Visual impairment, age-related cataract, and mortality. Arch Ophthalmol (2001) 1.55

Visual impairment and risk of hip fracture. Am J Epidemiol (2000) 1.51

Health status before and mortality after hip fracture. Am J Public Health (1996) 1.46

Evaluating the risk of dependence in activities of daily living among community-living older adults with mild to moderate cognitive impairment. J Gerontol A Biol Sci Med Sci (1995) 1.45

Older persons' perceptions of home and hospital as sites of treatment for acute illness. Am J Med (1999) 1.43

High-risk prescribing and incidence of frailty among older community-dwelling men. Clin Pharmacol Ther (2012) 1.43

The combined effects of baseline vulnerability and acute hospital events on the development of functional dependence among community-living older persons. J Gerontol A Biol Sci Med Sci (1999) 1.43

The cost effectiveness of a home hazard reduction program to reduce falls among older persons. Aust N Z J Public Health (2000) 1.40

Refractive associations with cataract: the Blue Mountains Eye Study. Invest Ophthalmol Vis Sci (1999) 1.38

Impairments in physical performance and cognitive status as predisposing factors for functional dependence among nondisabled older persons. J Gerontol A Biol Sci Med Sci (1996) 1.37

Serum parathyroid hormone is associated with increased mortality independent of 25-hydroxy vitamin d status, bone mass, and renal function in the frail and very old: a cohort study. J Clin Endocrinol Metab (2004) 1.25

Sensory impairment and driving: the Blue Mountains Eye Study. Am J Public Health (1999) 1.25

Predictors of recovery in activities of daily living among disabled older persons living in the community. J Gen Intern Med (1997) 1.25

Factors associated with undercorrected refractive errors in an older population: the Blue Mountains Eye Study. Br J Ophthalmol (2002) 1.22

Older persons' preferences for site of terminal care. Ann Intern Med (1999) 1.22

A taxonomy for goal setting in the care of persons with dementia. J Gen Intern Med (1998) 1.20

Delusions and behavioral disturbances in cognitively impaired elderly persons. J Am Geriatr Soc (1992) 1.19

Influence of fall related factors and bone strength on fracture risk in the frail elderly. Osteoporos Int (2007) 1.11

Impaired vision and other factors associated with driving cessation in the elderly: the Blue Mountains Eye Study. Clin Experiment Ophthalmol (2001) 1.11

The role of change in physical performance in determining risk for dependence in activities of daily living among nondisabled community-living elderly persons. J Clin Epidemiol (1997) 1.10

HIV and tuberculosis in rural sub-Saharan Africa: a cohort study with two year follow-up. Trans R Soc Trop Med Hyg (1999) 1.09

Goal-setting in clinical medicine. Soc Sci Med (1999) 1.09

A randomised trial of hip protector use by frail older women living in their own homes. Inj Prev (2003) 1.08

Self-report versus state records for identifying crashes among older drivers. J Gerontol A Biol Sci Med Sci (1997) 1.08

Environmental hazards and the risk of nonsyncopal falls in the homes of community-living older persons. Med Care (2000) 1.08

Hierarchical models to evaluate translational research: Connecticut collaboration for fall prevention. Contemp Clin Trials (2007) 1.06

Cohort study of vitamin C intake and cognitive impairment. Am J Epidemiol (1998) 1.06

Validation of dizziness as a possible geriatric syndrome. J Am Geriatr Soc (2001) 1.05

The design and implementation of a restorative care model for home care. Gerontologist (2001) 1.04

Serum parathyroid hormone predicts time to fall independent of vitamin D status in a frail elderly population. J Clin Endocrinol Metab (2004) 1.03

Asymmetry in optic disc parameters: the Blue Mountains Eye Study. Invest Ophthalmol Vis Sci (1999) 1.03

Cataract and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmic Epidemiol (1999) 1.03

Sensitivity and specificity of tests to detect eye disease in an older population. Ophthalmology (2001) 1.02

Diabetes, fasting blood glucose and age-related cataract: the Blue Mountains Eye Study. Ophthalmic Epidemiol (2000) 1.01

Who dies at home? Determinants of site of death for community-based long-term care patients. J Am Geriatr Soc (1999) 0.99

An impairment and disability assessment and treatment protocol for community-living elderly persons. Phys Ther (1994) 0.98

ED use by older victims of family violence. Ann Emerg Med (1997) 0.98

Use of vitamin supplements and cataract: the Blue Mountains Eye Study. Am J Ophthalmol (2001) 0.97

Visual function tests, eye disease and symptoms of visual disability: a population-based assessment. Clin Experiment Ophthalmol (2000) 0.96

Prevalence and vascular associations with migraine in older Australians. Aust N Z J Med (1998) 0.96

Oral bisphosphonates are associated with reduced mortality in frail older people: a prospective five-year study. Osteoporos Int (2010) 0.94

Postoperative sore throat and hoarseness following tracheal intubation using air or saline to inflate the cuff--a randomized controlled trial. Anaesth Intensive Care (2000) 0.94

Factors associated with short- versus long-term skilled nursing facility placement among community-living hip fracture patients. J Am Geriatr Soc (1990) 0.93

Physician awareness of alcohol use disorders among older patients. J Gen Intern Med (1998) 0.93

A population-based study of environmental hazards in the homes of older persons. Am J Public Health (1999) 0.92

Bilateral involvement by age related maculopathy lesions in a population. Br J Ophthalmol (1998) 0.92

Does increased sunlight exposure work as a strategy to improve vitamin D status in the elderly: a cluster randomised controlled trial. Osteoporos Int (2011) 0.91

Chronic diseases among older people in Amirkola, northern Islamic Republic of Iran. East Mediterr Health J (2011) 0.91

Case-control study of hazards in the home and risk of falls and hip fractures. Age Ageing (1996) 0.90

Risk factors for fractures of the wrist, shoulder and ankle: the Blue Mountains Eye Study. Osteoporos Int (2002) 0.89

Older person's preferences for home vs hospital care in the treatment of acute illness. Arch Intern Med (2000) 0.88

Plasma fibrinogen and other cardiovascular disease risk factors and cataract. Ophthalmic Epidemiol (1999) 0.88

Mycoplasma genitalium is associated with cervicitis and HIV infection in an urban Australian STI clinic population. Sex Transm Infect (2010) 0.88

Deaths observed in Medicare beneficiaries: average attributable fraction and its longitudinal extension for many diseases. Stat Med (2012) 0.88

Reproducibility of the Wisconsin cataract grading system in the Blue Mountains Eye Study. Ophthalmic Epidemiol (1997) 0.87

Lifestyle factors, medications, and disease influence bone mineral density in older men: findings from the CHAMP study. Osteoporos Int (2010) 0.86

The association between medications and falls in Australian nursing-home residents. Med J Aust (1994) 0.86

Older persons' preferences for site of treatment in acute illness. J Gen Intern Med (1998) 0.85