Systematic review of methods used in meta-analyses where a primary outcome is an adverse or unintended event.

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Published in BMC Med Res Methodol on May 03, 2012

Authors

Fiona C Warren1, Keith R Abrams, Su Golder, Alex J Sutton

Author Affiliations

1: Peninsula College of Medicine and Dentistry, St Luke's Campus, University of Exeter, Exeter, UK. fiona.warren@pcmd.ac.uk

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Quantifying heterogeneity in a meta-analysis. Stat Med (2002) 83.16

Operating characteristics of a rank correlation test for publication bias. Biometrics (1994) 47.97

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Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics (2000) 19.26

Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis (1985) 19.03

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Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry (1999) 8.04

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