Published in J Neurosurg on February 01, 1999
Diffusion in brain extracellular space. Physiol Rev (2008) 5.34
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro Oncol (2008) 1.59
Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions. Neuro Oncol (2007) 1.39
Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles. Brain Res (2007) 1.25
Multifunctional nanoparticles for brain tumor imaging and therapy. Adv Drug Deliv Rev (2013) 1.07
Comparative pharmacokinetics of 14C-sucrose in RG-2 rat gliomas after intravenous and convection-enhanced delivery. Neuro Oncol (2004) 1.01
Strategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma. Neuro Oncol (2015) 0.93
Interstitial infusion of glioma-targeted recombinant immunotoxin 8H9scFv-PE38. Mol Cancer Ther (2010) 0.85
Dynamic contrast-enhanced MRI of Gd-albumin delivery to the rat hippocampus in vivo by convection-enhanced delivery. J Neurosci Methods (2012) 0.84
Prolonged attenuation of amygdala-kindled seizure measures in rats by convection-enhanced delivery of the N-type calcium channel antagonists omega-conotoxin GVIA and omega-conotoxin MVIIA. J Pharmacol Exp Ther (2007) 0.84
The potential of theragnostic ¹²⁴I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma. Neuro Oncol (2014) 0.79
Allogeneic astrocytoma in immune competent dogs. Neoplasia (1999) 0.77
Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer. Ther Deliv (2015) 0.76
Toxicity evaluation of prolonged convection-enhanced delivery of small-molecule kinase inhibitors in naïve rat brainstem. Childs Nerv Syst (2014) 0.76
Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies. J Neurosurg (2016) 0.76
Toxicity evaluation of convection-enhanced delivery of small-molecule kinase inhibitors in naïve mouse brainstem. Childs Nerv Syst (2015) 0.75
The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest (2000) 9.51
Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest (1999) 7.40
Electron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans.?2UU. J Comp Neurol (1975) 6.58
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science (1997) 6.10
A global profile of germline gene expression in C. elegans. Mol Cell (2000) 5.97
Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg (1985) 5.91
Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. Proc Natl Acad Sci U S A (1973) 4.76
Fertilization and sperm competition in the nematode Caenorhabditis elegans. Dev Biol (1979) 3.78
An investigation into the effectiveness of an early intervention method for delayed language development in young children. Int J Lang Commun Disord (2000) 3.68
Earliest Homo. Nature (1992) 3.52
Characterization of temperature-sensitive, fertilization-defective mutants of the nematode caenorhabditis elegans. Genetics (1978) 2.68
Intersex, a temperature-sensitive mutant of the nematode Caenorhabditis elegans. Dev Biol (1978) 2.62
Experience with a clinical guideline for the treatment of ventilator-associated pneumonia. Crit Care Med (2001) 2.35
Larger sperm outcompete smaller sperm in the nematode Caenorhabditis elegans. Proc Biol Sci (1998) 2.35
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants. Infect Immun (1990) 2.32
Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans. J Cell Biol (1981) 2.18
Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics. J Mol Biol (1986) 2.16
Evaluation of an inspiratory muscle trainer in healthy humans. Respir Med (2001) 2.16
The influence of mini-BAL cultures on patient outcomes: implications for the antibiotic management of ventilator-associated pneumonia. Chest (1998) 2.15
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration. Trans R Soc Trop Med Hyg (1993) 2.15
Central nervous system mass lesions in the acquired immunodeficiency syndrome (AIDS). J Neurosurg (1984) 2.15
Vesicle fusion, pseudopod extension and amoeboid motility are induced in nematode spermatids by the ionophore monensin. Cell (1980) 2.09
Fitness to practise: Unbelievably arrogant. Br Dent J (2014) 2.03
Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. Genetics (1988) 2.01
Asthma Control Questionnaire in children: validation, measurement properties, interpretation. Eur Respir J (2010) 1.97
Simplified amino acid alphabets for protein fold recognition and implications for folding. Protein Eng (2000) 1.91
The initiation of spermiogenesis in the nematode Caenorhabditis elegans. Dev Biol (1983) 1.89
Stability of plasma concentrations of N and C terminal atrial natriuretic peptides at room temperature. Heart (1996) 1.79
Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology (1992) 1.78
The influence of access to a private attending physician on the withdrawal of life-sustaining therapies in the intensive care unit. Crit Care Med (1999) 1.77
Ca2+ dependence of tension and ADP production in segments of chemically skinned muscle fibers. Biochim Biophys Acta (1976) 1.75
Methods for fractionation and scintillation counting of radioisotope-labeled polyacrylamide gels. Anal Biochem (1970) 1.74
Evolution of sperm size in nematodes: sperm competition favours larger sperm. Proc Biol Sci (1999) 1.73
ENCORE: the effect of nutrient enrichment on coral reefs. Synthesis of results and conclusions. Mar Pollut Bull (2001) 1.69
A representational approach to patient education. J Nurs Scholarsh (2001) 1.68
Blockade of kit signaling induces transdifferentiation of interstitial cells of cajal to a smooth muscle phenotype. Gastroenterology (1999) 1.67
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Caenorhabditis elegans spermatozoan locomotion: amoeboid movement with almost no actin. J Cell Biol (1982) 1.66
The impact of the introduction of a rapid D-dimer assay on the diagnostic evaluation of suspected pulmonary embolism. Arch Intern Med (2001) 1.65
Molecular characterization of the surface layer proteins from Clostridium difficile. Mol Microbiol (2001) 1.65
Quasi-harmonic method for studying very low frequency modes in proteins. Biopolymers (1984) 1.64
A nematode gene required for sperm vesicle fusion. J Cell Sci (1997) 1.62
Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc Natl Acad Sci U S A (1999) 1.60
Risedronate therapy prevents corticosteroid-induced bone loss: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum (1999) 1.58
Sperm precedence in a hermaphroditic nematode (Caenorhabditis elegans) is due to competitive superiority of male sperm. Experientia (1995) 1.58
alpha-Helix dipole model and electrostatic stabilization of 4-alpha-helical proteins. Proc Natl Acad Sci U S A (1982) 1.57
The entry of antiviral and antiretroviral drugs into the central nervous system. J Neurovirol (1997) 1.56
What role for statins? A review and economic model. Health Technol Assess (1999) 1.53
Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212. J Pharmacol Exp Ther (1994) 1.52
Broad oxygen tolerance in the nematode Caenorhabditis elegans. J Exp Biol (2000) 1.51
A significant new contribution to radical head and neck surgery. The argon beam coagulator as an effective means of limiting blood loss. Arch Otolaryngol Head Neck Surg (1989) 1.50
Preoperative radiotherapy for adenocarcinoma of the rectosigmoid. Cancer (1976) 1.50
Which orthodontic archwire sequence? A randomized clinical trial. Eur J Orthod (2006) 1.50
Internal or external wall diameter for abdominal aortic aneurysm screening? Ann R Coll Surg Engl (2010) 1.49
Initiation of spermiogenesis in C. elegans: a pharmacological and genetic analysis. Dev Biol (1989) 1.48
Monoclonal antibodies that recognize a polypeptide antigenic determinant shared by multiple Caenorhabditis elegans sperm-specific proteins. J Cell Biol (1986) 1.47
Membrane and cytoplasmic proteins are transported in the same organelle complex during nematode spermatogenesis. J Cell Biol (1986) 1.47
Caenorhabditis elegans fertilization-defective mutants with abnormal sperm. Genetics (1980) 1.47
A comparative analysis of patients with early-onset vs late-onset nosocomial pneumonia in the ICU setting. Chest (2000) 1.46
Assessing the viability of mutant and manipulated sperm by artificial insemination of Caenorhabditis elegans. Genetics (1994) 1.44
Predictive factors for prolonged survival in acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy. Ann Neurol (1998) 1.43
Lactose and fatty acid synthesis in lactating-rat mammary gland. Effects of starvation, re-feeding, and administration of insulin, adrenaline, streptozotocin and 2-bromo-alpha-ergocryptine. Biochem J (1984) 1.42
Slower rise of exhaled breath temperature in chronic obstructive pulmonary disease. Eur Respir J (2003) 1.42
Use of the internet by infertile couples. Fertil Steril (2000) 1.40
Neuroradiologic findings in AIDS: a review of 200 cases. AJR Am J Roentgenol (1986) 1.39
A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals. J Virol (2001) 1.37
Intrinsic pKas of ionizable residues in proteins: an explicit solvent calculation for lysozyme. Proteins (1994) 1.34
Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes. Development (1997) 1.31
The long-term effects of 5-fluorouracil and sodium butyrate on human Tenon's fibroblasts. Invest Ophthalmol Vis Sci (1992) 1.29
Membrane flow during nematode spermiogenesis. J Cell Biol (1982) 1.27
The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin. Genes Dev (1995) 1.26
Exhaled ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2000) 1.21
Increased competitiveness of nematode sperm bearing the male X chromosome. Proc Natl Acad Sci U S A (1997) 1.20
A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. J Med Food (2007) 1.19
Hypercalcemia and gastric secretion in man. J Appl Physiol (1966) 1.19
Iterative sequence/secondary structure search for protein homologs: comparison with amino acid sequence alignments and application to fold recognition in genome databases. Bioinformatics (2000) 1.17
Molecular dynamics simulation of solvated protein at high pressure. Biochemistry (1992) 1.14
Neurosurgical implications of the acquired immunodeficiency syndrome (AIDS). Clin Neurosurg (1988) 1.13
Primary central nervous system lymphomas: natural history and response to radiation therapy in 55 patients with acquired immunodeficiency syndrome. J Neurosurg (1990) 1.13
Hormonal therapies for early breast cancer: systematic review and economic evaluation. Health Technol Assess (2007) 1.12
A national survey of certified, recertified, and noncertified oncology nurses: comparisons and contrasts. Oncol Nurs Forum (1999) 1.11
A sperm-supplied product essential for initiation of normal embryogenesis in Caenorhabditis elegans is encoded by the paternal-effect embryonic-lethal gene, spe-11. Dev Biol (1989) 1.11
Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol. Br J Pharmacol (2008) 1.10
Relationships between certification and job perceptions of oncology nurses. Oncol Nurs Forum (2001) 1.10
Expression of epidermal growth factor receptor in invasive transitional cell carcinoma of the urinary bladder. A multivariate survival analysis. Am J Clin Pathol (1994) 1.09
Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? AJR Am J Roentgenol (1999) 1.09
Bacillus subtilis ORF yybQ encodes a manganese-dependent inorganic pyrophosphatase with distinctive properties: the first of a new class of soluble pyrophosphatase? Microbiology (1998) 1.09
Assembly of bacteriophage T4 tail fibers. II. Isolation and characterization of tail fiber precursors. J Mol Biol (1970) 1.09
Identification of a large multigene family encoding the major sperm protein of Caenorhabditis elegans. J Mol Biol (1983) 1.08
The location of the major protein in Caenorhabditis elegans sperm and spermatocytes. Dev Biol (1982) 1.08
Genetic and molecular analysis of spe-27, a gene required for spermiogenesis in Caenorhabditis elegans hermaphrodites. Genetics (1996) 1.08
The Caenorhabditis elegans spe-6 gene is required for major sperm protein assembly and shows second site non-complementation with an unlinked deficiency. Genetics (1993) 1.08
Molecular dynamics of myoglobin at 298 degrees K. Results from a 300-ps computer simulation. Biophys J (1985) 1.08
Search for stopped Gluinos in pp collisions at square root s=7 TeV. Phys Rev Lett (2011) 1.07
Histopathologic predictors of the behavior of surgically treated stage IB squamous cell carcinoma of the cervix. A Gynecologic Oncology Group study. Cancer (1992) 1.07
Permeability of lactating-rat mammary gland Golgi membranes to monosaccharides. Biochem J (1980) 1.07
Assembly of bacteriophage T4 tail fibers. 3. Genetic control of the major tail fiber polypeptides. J Mol Biol (1971) 1.07
Global folding of proteins using a limited number of distance constraints. Protein Eng (1993) 1.06
Exhalation flow and pressure-controlled reservoir collection of exhaled nitric oxide for remote and delayed analysis. Thorax (1998) 1.04
An improved transverse destaining apparatus for acrylamide gels. Anal Biochem (1970) 1.04