Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

PubWeight™: 2.43‹?› | Rank: Top 2%

🔗 View Article (PMID 9988274)

Published in Nat Genet on February 01, 1999

Authors

Y Corda1, V Schramke, M P Longhese, T Smokvina, V Paciotti, V Brevet, E Gilson, V Géli

Author Affiliations

1: Laboratoire d'Ingénierie et de Dynamique des Systèmes Macromoléculaires, CNRS, Marseille, France.

Articles citing this

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. Genes Dev (2001) 6.28

The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J (2001) 5.34

A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3. Proc Natl Acad Sci U S A (2001) 3.87

Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol (2005) 2.48

Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 1.97

The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation. Cell (2005) 1.94

Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression. Mol Cell Biol (2000) 1.93

Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell (2000) 1.93

Natural and pharmacological regulation of telomerase. Nucleic Acids Res (2002) 1.92

Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol (2006) 1.84

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics (2002) 1.78

A homeotic mutation in the trithorax SET domain impedes histone binding. Genes Dev (2001) 1.78

Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres. Nucleic Acids Res (2000) 1.74

Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. EMBO J (2005) 1.55

Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.46

Set1 is required for meiotic S-phase onset, double-strand break formation and middle gene expression. EMBO J (2004) 1.46

Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. Genetics (2000) 1.45

Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J (2001) 1.41

The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3. Mol Cell Biol (2004) 1.38

The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev (2001) 1.34

Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Nucleic Acids Res (2002) 1.27

Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res (2007) 1.23

Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription. PLoS Genet (2012) 1.21

Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway. PLoS Genet (2010) 1.19

A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae. Genetics (2008) 1.09

Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Eukaryot Cell (2003) 1.07

Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons. Epigenetics (2014) 0.99

Mutagenesis of pairwise combinations of histone amino-terminal tails reveals functional redundancy in budding yeast. Proc Natl Acad Sci U S A (2012) 0.90

Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex. Mol Cell Biol (2005) 0.89

Origin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae. J Biol Chem (2008) 0.88

Mrc1, a non-essential DNA replication protein, is required for telomere end protection following loss of capping by Cdc13, Yku or telomerase. Mol Genet Genomics (2007) 0.87

Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. BMC Dev Biol (2008) 0.83

An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitors. PLoS One (2014) 0.82

Need telomere maintenance? Call 911. Cell Div (2007) 0.81

The Set1/COMPASS histone H3 methyltransferase helps regulate mitosis with the CDK1 and NIMA mitotic kinases in Aspergillus nidulans. Genetics (2014) 0.80

Forever hopeful relations: chromatin, telomeres and checkpoints. Nat Genet (1999) 0.79

A mutation in yeast Tel1p that causes differential effects on the DNA damage checkpoint and telomere maintenance. Curr Genet (2005) 0.78

Spp1 at the crossroads of H3K4me3 regulation and meiotic recombination. Epigenetics (2013) 0.78

Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance. Cell Cycle (2010) 0.78

The histone methyltransferases Set5 and Set1 have overlapping functions in gene silencing and telomere maintenance. Epigenetics (2016) 0.75

Rad6-Bre1-mediated H2B ubiquitination regulates telomere replication by promoting telomere-end resection. Nucleic Acids Res (2017) 0.75

Articles by these authors

A protein-counting mechanism for telomere length regulation in yeast. Science (1997) 4.79

A family of dispersed repetitive extragenic palindromic DNA sequences in E. coli. EMBO J (1984) 4.07

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell (1993) 3.77

Telomeric localization of TRF2, a novel human telobox protein. Nat Genet (1997) 3.23

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev (1996) 2.85

The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes Dev (2000) 2.82

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J (1997) 2.48

Cell cycle restriction of telomere elongation. Curr Biol (2000) 2.46

Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J (1999) 2.45

Sequence of the malK gene in E.coli K12. Nucleic Acids Res (1982) 2.43

Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J (1999) 2.37

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J (1998) 2.34

Cleavage of colicin D is necessary for cell killing and requires the inner membrane peptidase LepB. Mol Cell (2001) 2.33

Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein. Genes Dev (1996) 2.02

The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res (1996) 1.98

The integrated conjugative plasmid pSAM2 of Streptomyces ambofaciens is related to temperate bacteriophages. EMBO J (1989) 1.80

Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway. Mol Cell Biol (2001) 1.53

Cooperation at a distance between silencers and proto-silencers at the yeast HML locus. EMBO J (1996) 1.50

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast. EMBO J (1999) 1.50

A role for DNA primase in coupling DNA replication to DNA damage response. EMBO J (1997) 1.48

Transmembrane alpha-helix interactions are required for the functional assembly of the Escherichia coli Tol complex. J Mol Biol (1995) 1.47

Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. Genetics (2000) 1.45

Nuclear envelope associated protein that binds telomeric DNAs. Mol Reprod Dev (2000) 1.43

The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoints in budding yeast. Nucleic Acids Res (1996) 1.41

Extensive homology between membrane-associated components of histidine and maltose transport systems of Salmonella typhimurium and Escherichia coli. J Biol Chem (1982) 1.39

The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev (2001) 1.34

An activation-independent role of transcription factors in insulator function. EMBO Rep (2001) 1.32

Mutations in the gene encoding the 34 kDa subunit of yeast replication protein A cause defective S phase progression. J Mol Biol (1995) 1.30

Palindromic units from E. coli as binding sites for a chromoid-associated protein. FEBS Lett (1986) 1.27

Structural analysis of loci involved in pSAM2 site-specific integration in Streptomyces. Plasmid (1989) 1.24

Structural and functional diversity among bacterial interspersed mosaic elements (BIMEs). Mol Microbiol (1994) 1.22

Ku-deficient yeast strains exhibit alternative states of silencing competence. EMBO Rep (2001) 1.16

Bacterial interspersed mosaic elements (BIMEs) are a major source of sequence polymorphism in Escherichia coli intergenic regions including specific associations with a new insertion sequence. Genetics (1997) 1.16

Mutations in conserved yeast DNA primase domains impair DNA replication in vivo. Proc Natl Acad Sci U S A (1991) 1.12

Functional cooperation of the mitochondrial processing peptidase subunits. J Mol Biol (1997) 1.11

Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta. J Biol Chem (1993) 1.11

Proteins that bind to double-stranded regions of telomeric DNA. Trends Cell Biol (1997) 1.10

Rap1p and telomere length regulation in yeast. Ciba Found Symp (1997) 1.09

Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J Struct Biol (1995) 1.07

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy. Oncogene (2010) 1.06

Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res (2000) 1.05

Large telomerase RNA, telomere length heterogeneity and escape from senescence in Candida glabrata. FEBS Lett (2009) 1.05

Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences. Nucleic Acids Res (1999) 1.02

The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane. Cold Spring Harb Symp Quant Biol (1993) 1.01

The mitochondrial processing peptidase: function and specificity. Experientia (1996) 1.00

Quantification of group A colicin import sites. J Bacteriol (1995) 1.00

Telomere maintenance, function and evolution: the yeast paradigm. Chromosome Res (2005) 1.00

Identification of a gene encoding the replication initiator protein of the Streptomyces integrating element, pSAM2. Plasmid (1994) 0.99

Protosilencers in Saccharomyces cerevisiae subtelomeric regions. Genetics (2001) 0.98

A haploid-specific transcriptional response to irradiation in Saccharomyces cerevisiae. Nucleic Acids Res (2005) 0.97

The channel domain of colicin A is inhibited by its immunity protein through direct interaction in the Escherichia coli inner membrane. EMBO J (1996) 0.97

The AprX protein of Pseudomonas aeruginosa: a new substrate for the Apr type I secretion system. Gene (2001) 0.95

In vitro binding of nucleolin to double-stranded telomeric DNA. Biochem Biophys Res Commun (2000) 0.94

Immunity proteins to pore-forming colicins: structure-function relationships. Mol Microbiol (1994) 0.94

malM, a new gene of the maltose regulon in Escherichia coli K12. I. malM is the last gene of the malK-lamB operon and encodes a periplasmic protein. J Mol Biol (1986) 0.92

Optimal Cultural and Physiological Conditions for Handling Streptomyces rimosus Protoplasts. Appl Environ Microbiol (1982) 0.92

Site-specific integration of the Streptomyces plasmid pSAM2 in Mycobacterium smegmatis. Mol Microbiol (1991) 0.92

The colicin A pore-forming domain fused to mitochondrial intermembrane space sorting signals can be functionally inserted into the Escherichia coli plasma membrane by a mechanism that bypasses the Tol proteins. Mol Microbiol (1994) 0.91

Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression. EMBO J (2001) 0.91

Role of the telomeric DNA-binding protein TRF2 in the stability of human chromosome ends. Bioessays (1998) 0.90

Chromatin: a sticky silence. Curr Biol (1996) 0.90

Bacterial interspersed mosaic elements (BIMEs) are present in the genome of Klebsiella. Mol Microbiol (1993) 0.87

Integration of the colicin A pore-forming domain into the cytoplasmic membrane of Escherichia coli. J Mol Biol (1999) 0.86

TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts. Oncogene (2006) 0.86

Lactobacillus rhamnosus CNCM I-3690 and the commensal bacterium Faecalibacterium prausnitzii A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice. Gut Microbes (2015) 0.83

The mitochondrial processing peptidase behaves as a zinc-metallopeptidase. J Mol Biol (1998) 0.83

Interactions of colicin A domains with phospholipid monolayers and liposomes: relevance to the mechanism of action. Biochemistry (1989) 0.81

malM, a new gene of the maltose regulon in Escherichia coli K12. II. Mutations affecting the signal peptide of the MalM protein. J Mol Biol (1986) 0.81

Genetic interactions in Streptomyces rimosus mediated by conjugation and by protoplast fusion. J Gen Microbiol (1983) 0.81

Periplasmic binding protein dependent transport system for maltose and maltodextrins: some recent studies. FEMS Microbiol Rev (1989) 0.81

A comparative study of protoplast preparation and regeneration in Streptomyces rimosus and Streptomyces lividans. Microbiologica (1986) 0.79

Benefits and risks of screening mammography in women with BRCA1 and BRCA2 mutations. JAMA (1997) 0.78

Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells. Leukemia (2009) 0.77

Comparative effects of hindlimb suspension and exercise on skeletal muscle myosin isozymes in rats. Eur J Appl Physiol Occup Physiol (1990) 0.76

Colicin A lysis protein promotes extracellular release of active human growth hormone accumulated in Escherichia coli cytoplasm. Biochimie (1993) 0.76

[Telomere-binding activity of Schizosaccharomyces pombe yeasts]. Mol Biol (Mosk) (2000) 0.75

[Not Available]. Episteme (1977) 0.75

New indices of arterial oxygen status: an experience on 168 subjects. Scand J Clin Lab Invest Suppl (1990) 0.75