CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction (CADUCEUS)

Clinical Trial ID NCT00893360

PubWeight™ 67.70‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 2012 9.86
2 Heart regeneration. Nature 2011 5.91
3 Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 2012 3.48
4 Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res 2011 2.76
5 Intracoronary cardiosphere-derived cells after myocardial infarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction). J Am Coll Cardiol 2013 2.34
6 Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells. Circulation 2011 2.29
7 Cardiac cell therapy: where we've been, where we are, and where we should be headed. Br Med Bull 2011 2.26
8 Characterization and functionality of cardiac progenitor cells in congenital heart patients. Circulation 2011 1.99
9 Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies. Circ Res 2011 1.98
10 Maternally inherited essential hypertension is associated with the novel 4263A>G mutation in the mitochondrial tRNAIle gene in a large Han Chinese family. Circ Res 2011 1.81
11 Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration. Circ Res 2011 1.77
12 Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells. Stem Cells 2010 1.63
13 Effects of age and heart failure on human cardiac stem cell function. Am J Pathol 2011 1.57
14 Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair. Cardiovasc Res 2010 1.41
15 Role of stem cells in cardiovascular biology. J Thromb Haemost 2011 1.31
16 The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction. Circ Res 2011 1.14
17 Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel. Biomaterials 2012 1.14
18 Relative roles of CD90 and c-kit to the regenerative efficacy of cardiosphere-derived cells in humans and in a mouse model of myocardial infarction. J Am Heart Assoc 2014 1.13
19 Concise review: the role of clinical trials in deciphering mechanisms of action of cardiac cell-based therapy. Stem Cells Transl Med 2011 1.09
20 Challenges for heart disease stem cell therapy. Vasc Health Risk Manag 2012 1.02
21 Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres. J Biomed Biotechnol 2012 0.97
22 Potential of cardiac stem/progenitor cells and induced pluripotent stem cells for cardiac repair in ischaemic heart disease. Clin Sci (Lond) 2013 0.95
23 Intramyocardial injection of platelet gel promotes endogenous repair and augments cardiac function in rats with myocardial infarction. J Am Coll Cardiol 2012 0.95
24 Secondary sphere formation enhances the functionality of cardiac progenitor cells. Mol Ther 2012 0.94
25 The survey on cellular and engineered tissue therapies in Europe in 2011. Tissue Eng Part A 2013 0.91
26 Stem cell therapy: pieces of the puzzle. J Cardiovasc Transl Res 2009 0.91
27 Serum and supplement optimization for EU GMP-compliance in cardiospheres cell culture. J Cell Mol Med 2014 0.90
28 Stem cell therapy for cardiac dysfunction. Springerplus 2014 0.90
29 Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic agent trastuzumab. Stem Cells Transl Med 2012 0.89
30 Current stem cell delivery methods for myocardial repair. Biomed Res Int 2012 0.89
31 SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling. Int J Mol Med 2014 0.88
32 Materials science and tissue engineering: repairing the heart. Mayo Clin Proc 2013 0.87
33 Cardiosphere-derived cell sheet primed with hypoxia improves left ventricular function of chronically infarcted heart. Am J Transl Res 2015 0.86
34 Empowering Adult Stem Cells for Myocardial Regeneration V2.0: Success in Small Steps. Circ Res 2016 0.81
35 Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering. Biomark Insights 2015 0.80
36 Human cardiospheres as a source of multipotent stem and progenitor cells. Stem Cells Int 2013 0.80
37 Challenges in the translation of cardiovascular cell therapy. J Nucl Med 2010 0.79
38 Cardiac Regenerative Medicine: The Potential of a New Generation of Stem Cells. Transfus Med Hemother 2016 0.79
39 Delayed administration of allogeneic cardiac stem cell therapy for acute myocardial infarction could ameliorate adverse remodeling: experimental study in swine. J Transl Med 2015 0.78
40 Characterization of superoxide dismutases in cardiac progenitor cells demonstrates a critical role for manganese superoxide dismutase. Stem Cells Dev 2012 0.78
41 Murine Models Demonstrate Distinct Vasculogenic and Cardiomyogenic cKit+ Lineages in the Heart. Circ Res 2016 0.78
42 Progenitor/stem cell transplantation for repair of myocardial infarction: Hype or hope? Ann Palliat Med 2012 0.77
43 Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model. PLoS One 2016 0.75
44 Activation of Notch1 signalling promotes multi-lineage differentiation of c-Kit(POS)/NKX2.5(POS) bone marrow stem cells: implication in stem cell translational medicine. Stem Cell Res Ther 2015 0.75
45 Cell therapy-a 21st century hope for treating cardiovascular disease-a five-year retrospective and predictive view. Am Heart Hosp J 2011 0.75
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