Published in Mayo Clin Proc on August 01, 2013
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO) (SCIPIO) | NCT00474461
Safety and Feasibility of the Injectable BL-1040 Implant | NCT00557531
From cardiac tissue engineering to heart-on-a-chip: beating challenges. Biomed Mater (2015) 0.94
Making it stick: chasing the optimal stem cells for cardiac regeneration. Expert Rev Cardiovasc Ther (2014) 0.91
Pluripotent stem cell derived cardiomyocytes for cardiac repair. Curr Treat Options Cardiovasc Med (2014) 0.82
Galnt1 is required for normal heart valve development and cardiac function. PLoS One (2015) 0.81
Acceleration of wound healing by α-gal nanoparticles interacting with the natural anti-Gal antibody. J Immunol Res (2015) 0.80
Development of a Cyclic Strain Bioreactor for Mechanical Enhancement and Assessment of Bioengineered Myocardial Constructs. Cardiovasc Eng Technol (2015) 0.79
Three-dimensional poly-(ε-caprolactone) nanofibrous scaffolds directly promote the cardiomyocyte differentiation of murine-induced pluripotent stem cells through Wnt/β-catenin signaling. BMC Cell Biol (2015) 0.77
New strategies for improving stem cell therapy in ischemic heart disease. Heart Fail Rev (2016) 0.77
Designing Biopolymer Microthreads for Tissue Engineering and Regenerative Medicine. Curr Stem Cell Rep (2016) 0.75
Advanced Strategies for End-Stage Heart Failure: Combining Regenerative Approaches with LVAD, a New Horizon? Front Surg (2015) 0.75
Cardiovascular Tissue Engineering: Preclinical Validation to Bedside Application. Physiology (Bethesda) (2016) 0.75
The extracellular microscape governs mesenchymal stem cell fate. J Biol Eng (2016) 0.75
A regenerative cardiac patch formed by spray painting of biomaterials onto the heart. Tissue Eng Part C Methods (2017) 0.75
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell (2003) 18.09
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol (2007) 14.48
Concern Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet (2011) 11.45
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature (2008) 10.27
Clinical transplantation of a tissue-engineered airway. Lancet (2008) 10.04
Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet (2012) 9.86
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature (2005) 9.44
Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med (2010) 9.19
Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res (2004) 8.41
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet (2006) 7.64
Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation (1987) 7.14
Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09
Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell (2006) 6.19
Concern Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study. Lancet (2011) 5.79
Effectiveness of haemodialysis access with an autologous tissue-engineered vascular graft: a multicentre cohort study. Lancet (2009) 5.16
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A (2012) 4.85
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med (2006) 4.74
Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study. Lancet (2012) 4.54
Tissue engineering of a differentiated cardiac muscle construct. Circ Res (2002) 4.50
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol (2004) 4.50
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature (2010) 4.38
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc Natl Acad Sci U S A (2004) 4.13
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature (2011) 4.10
Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater (2008) 4.00
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature (2012) 3.63
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med (2012) 3.53
Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J Am Coll Cardiol (2004) 3.44
Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. Circulation (2004) 3.29
Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ Res (2011) 3.25
Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ Res (2002) 3.10
Theoretical impact of the injection of material into the myocardium: a finite element model simulation. Circulation (2006) 2.84
Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res (2007) 2.74
Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes. Biophys J (2008) 2.61
Proangiogenic scaffolds as functional templates for cardiac tissue engineering. Proc Natl Acad Sci U S A (2010) 2.58
Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci U S A (2009) 2.51
Biomaterials for the treatment of myocardial infarction. J Am Coll Cardiol (2006) 2.48
Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction. Tissue Eng (2004) 2.42
Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering. Biomaterials (2009) 2.41
Three-dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system. FASEB J (1997) 2.33
A tissue-engineered jellyfish with biomimetic propulsion. Nat Biotechnol (2012) 2.30
Optimizing engineered heart tissue for therapeutic applications as surrogate heart muscle. Circulation (2006) 2.26
Bioengineered cardiac grafts: A new approach to repair the infarcted myocardium? Circulation (2000) 2.25
Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Stem Cells Dev (2013) 2.24
Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng (2006) 2.20
Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am J Physiol (1999) 2.19
Study of non-muscle cells of the adult mammalian heart: a fine structural analysis and distribution. Cytobios (1980) 2.09
In vivo engineering of organs: the bone bioreactor. Proc Natl Acad Sci U S A (2005) 2.04
Development of a drug screening platform based on engineered heart tissue. Circ Res (2010) 2.04
Effect of injectable alginate implant on cardiac remodeling and function after recent and old infarcts in rat. Circulation (2008) 2.03
Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization. Biotechnol Bioeng (1999) 2.00
Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model. Circulation (2012) 1.98
Electrical stimulation systems for cardiac tissue engineering. Nat Protoc (2009) 1.97
Transplantation of a tissue-engineered human vascularized cardiac muscle. Tissue Eng Part A (2010) 1.97
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng Part A (2012) 1.95
Prevascularization of cardiac patch on the omentum improves its therapeutic outcome. Proc Natl Acad Sci U S A (2009) 1.91
Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J (2006) 1.90
Injectable hydrogel properties influence infarct expansion and extent of postinfarction left ventricular remodeling in an ovine model. Proc Natl Acad Sci U S A (2010) 1.87
Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation. Proc Natl Acad Sci U S A (2005) 1.85
Influence of substrate stiffness on the phenotype of heart cells. Biotechnol Bioeng (2010) 1.82
Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology. PLoS One (2011) 1.73
Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro. Biomaterials (2010) 1.71
Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction. Sci Transl Med (2013) 1.69
Challenges in cardiac tissue engineering. Tissue Eng Part B Rev (2010) 1.66
Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. J Biomed Mater Res A (2008) 1.63
Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture. PLoS One (2010) 1.60
Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction. J Am Coll Cardiol (2012) 1.60
Novel injectable bioartificial tissue facilitates targeted, less invasive, large-scale tissue restoration on the beating heart after myocardial injury. Circulation (2005) 1.59
Bone marrow-derived mesenchymal stromal cells express cardiac-specific markers, retain the stromal phenotype, and do not become functional cardiomyocytes in vitro. Stem Cells (2008) 1.54
Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine. J Am Coll Cardiol (2009) 1.54
Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography. Am J Physiol Cell Physiol (2003) 1.48
Biomaterials for the treatment of myocardial infarction: a 5-year update. J Am Coll Cardiol (2011) 1.47
Improved vascular organization enhances functional integration of engineered skeletal muscle grafts. Proc Natl Acad Sci U S A (2011) 1.45
Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case. Surg Today (2011) 1.44
Scaffold-free human cardiac tissue patch created from embryonic stem cells. Tissue Eng Part A (2009) 1.42
In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels. Nat Commun (2013) 1.41
Percutaneous intramyocardial stem cell injection in patients with acute myocardial infarction: first-in-man study. Heart (2009) 1.41
Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Arrhythm Electrophysiol (2013) 1.38
Intra-myocardial biomaterial injection therapy in the treatment of heart failure: Materials, outcomes and challenges. Acta Biomater (2010) 1.33
Heart muscle engineering: an update on cardiac muscle replacement therapy. Cardiovasc Res (2006) 1.32
Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues. Biomaterials (2009) 1.31
Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function. Biomaterials (2011) 1.30
Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium. Transplantation (2005) 1.30
Functional improvement of infarcted heart by co-injection of embryonic stem cells with temperature-responsive chitosan hydrogel. Tissue Eng Part A (2009) 1.29
A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro. Acta Biomater (2012) 1.27
Concise review: tissue-engineered vascular grafts for cardiac surgery: past, present, and future. Stem Cells Transl Med (2012) 1.26
Pre-vascularization of in vitro three-dimensional tissues created by cell sheet engineering. Biomaterials (2010) 1.25
Injectable hydrogel therapies and their delivery strategies for treating myocardial infarction. Expert Opin Drug Deliv (2012) 1.23
Biphasic electrical field stimulation aids in tissue engineering of multicell-type cardiac organoids. Tissue Eng Part A (2008) 1.20
Injectable acellular hydrogels for cardiac repair. J Cardiovasc Transl Res (2011) 1.19
Biodegradable collagen patch with covalently immobilized VEGF for myocardial repair. Biomaterials (2010) 1.19
A synthetic non-degradable polyethylene glycol hydrogel retards adverse post-infarct left ventricular remodeling. J Card Fail (2009) 1.19
Transplantation of marrow-derived cardiac stem cells carried in fibrin improves cardiac function after myocardial infarction. Tissue Eng Part A (2010) 1.17
In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies. Stem Cells (2010) 1.15
Prognostic value of left ventricular end-systolic volume index as a predictor of heart failure hospitalization in stable coronary artery disease: data from the Heart and Soul Study. J Am Soc Echocardiogr (2008) 1.13
Stress and strain as regulators of myocardial growth. Prog Biophys Mol Biol (1998) 1.13
Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy. Circ Res (2002) 1.12
Parthenogenetic stem cells for tissue-engineered heart repair. J Clin Invest (2013) 1.11
Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering. Biomaterials (2009) 2.41
Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction. Sci Transl Med (2013) 1.69
Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture. PLoS One (2010) 1.60
Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction. J Am Coll Cardiol (2012) 1.60
Biomaterials for the treatment of myocardial infarction: a 5-year update. J Am Coll Cardiol (2011) 1.47
Design and characterization of an injectable pericardial matrix gel: a potentially autologous scaffold for cardiac tissue engineering. Tissue Eng Part A (2010) 1.39
Injectable materials for the treatment of myocardial infarction and heart failure: the promise of decellularized matrices. J Cardiovasc Transl Res (2010) 1.28
A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro. Acta Biomater (2012) 1.27
Injectable hydrogel therapies and their delivery strategies for treating myocardial infarction. Expert Opin Drug Deliv (2012) 1.23
Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy. J Thorac Cardiovasc Surg (2009) 1.21
Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue. Biomaterials (2013) 1.11
Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A (2011) 1.10
Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction. PLoS One (2011) 1.06
Injectable extracellular matrix derived hydrogel provides a platform for enhanced retention and delivery of a heparin-binding growth factor. Acta Biomater (2012) 1.05
Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. Eur Cell Mater (2012) 1.03
Injectable hydrogel scaffold from decellularized human lipoaspirate. Acta Biomater (2010) 1.00
Tailoring material properties of a nanofibrous extracellular matrix derived hydrogel. Nanotechnology (2011) 0.97
Modulation of material properties of a decellularized myocardial matrix scaffold. Macromol Biosci (2011) 0.97
Fibroblasts influence muscle progenitor differentiation and alignment in contact independent and dependent manners in organized co-culture devices. Biomed Microdevices (2013) 0.95
Electrochemically controllable conjugation of proteins on surfaces. Bioconjug Chem (2007) 0.88
Myocardial matrix-polyethylene glycol hybrid hydrogels for tissue engineering. Nanotechnology (2013) 0.87
Patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair. J Cardiovasc Transl Res (2011) 0.85
Antibacterial and cell-adhesive polypeptide and poly(ethylene glycol) hydrogel as a potential scaffold for wound healing. Acta Biomater (2011) 0.83
Award winner for outstanding research in the PhD category, 2014 Society for Biomaterials annual meeting and exposition, Denver, Colorado, April 16-19, 2014: Decellularized adipose matrix hydrogels stimulate in vivo neovascularization and adipose formation. J Biomed Mater Res A (2014) 0.81
Cardiac-Derived Extracellular Matrix Enhances Cardiogenic Properties of Human Cardiac Progenitor Cells. Cell Transplant (2015) 0.81
Injectable myocardial matrix as a scaffold for myocardial tissue engineering. Conf Proc IEEE Eng Med Biol Soc (2009) 0.80
A co-culture device with a tunable stiffness to understand combinatorial cell-cell and cell-matrix interactions. Integr Biol (Camb) (2013) 0.78
Human cardiomyogenesis and the need for systems biology analysis. Wiley Interdiscip Rev Syst Biol Med (2010) 0.78
Tunable protein release from acetalated dextran microparticles: a platform for delivery of protein therapeutics to the heart post-MI. Biomacromolecules (2013) 0.78
Oxime cross-linked injectable hydrogels for catheter delivery. Adv Mater (2013) 0.78
Injectable ECM scaffolds for cardiac repair. Methods Mol Biol (2014) 0.78
In vivo response to dynamic hyaluronic acid hydrogels. Acta Biomater (2013) 0.77
Self-Assembled Colloidal Gel Using Cell Membrane-Coated Nanosponges as Building Blocks. ACS Nano (2017) 0.75