Pilot Trial of Statin Use in Burn Patients (BURNSTAT)

Clinical Trial ID NCT00978419

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975 301.74
2 The hospital anxiety and depression scale. Acta Psychiatr Scand 1983 121.58
3 EuroQol--a new facility for the measurement of health-related quality of life. Health Policy 1990 59.70
4 STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION. JAMA 1963 38.91
5 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003 28.68
6 Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 1990 16.54
7 Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004 11.27
8 Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001 10.63
9 Measurement of functional activities in older adults in the community. J Gerontol 1982 10.07
10 Power and sample size calculations. A review and computer program. Control Clin Trials 1990 9.58
11 Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001 7.14
12 The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): socio-demographic correlates, reliability, validity and some norms. Psychol Med 1989 4.77
13 Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology 2006 4.03
14 Intensive Care Delirium Screening Checklist: evaluation of a new screening tool. Intensive Care Med 2001 3.87
15 The safety of statins in clinical practice. Lancet 2007 3.85
16 Structural mechanism for statin inhibition of HMG-CoA reductase. Science 2001 3.45
17 Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 2001 3.23
18 Statins and sepsis: multiple modifications at multiple levels. Lancet Infect Dis 2007 2.84
19 Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004 2.82
20 The association between delirium and cognitive decline: a review of the empirical literature. Neuropsychol Rev 2004 2.72
21 Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clin Pharmacokinet 1997 2.67
22 Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients. Crit Care 2005 2.53
23 Delirium in the intensive care unit: occurrence and clinical course in older patients. J Am Geriatr Soc 2003 2.53
24 Delirium and its motoric subtypes: a study of 614 critically ill patients. J Am Geriatr Soc 2006 2.49
25 Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patients. J Trauma 2008 2.46
26 HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis. Circulation 2004 2.30
27 Statin treatment after onset of sepsis in a murine model improves survival. Circulation 2005 2.08
28 Performance of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as a screening test for dementia. Psychol Med 1991 2.02
29 Statins and sepsis. Br J Anaesth 2008 1.80
30 Motoric subtypes of delirium in mechanically ventilated surgical and trauma intensive care unit patients. Intensive Care Med 2007 1.69
31 Quality of life, emotional, and cognitive function following acute respiratory distress syndrome. J Int Neuropsychol Soc 2004 1.42
32 Mortality and causes of death in a burn centre. Burns 2008 1.28
33 Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide. Br J Anaesth 2007 1.15
34 Comparison of WBC, ESR, CRP and PCT serum levels in septic and non-septic burn cases. Burns 2008 1.09
35 Alterations of acute phase reaction and cytokine production in patients following severe burn injury. Burns 2002 1.03
36 Statins in the intensive care unit. Curr Opin Crit Care 2006 1.00
37 Effect of preinjury statin use on mortality and septic shock in elderly burn patients. J Trauma 2010 0.95
38 Distribution of ferritin-conjugated lectins on sialidase-treated membranes of human erythrocytes. Biochim Biophys Acta 1975 0.90
39 Procalcitonin as a marker for the early diagnosis of severe infection after thermal injury. J Burn Care Rehabil 1999 0.89
40 Opioid and benzodiazepine withdrawal syndrome in adult burn patients. Am Surg 2000 0.86
41 In vivo confirmation of the role of statins in reducing nitric oxide and C-reactive protein levels in peripheral arterial disease. Eur J Vasc Endovasc Surg 2009 0.84
42 [Plasma endotoxin, procalcitonin, C-reactive protein, and organ functions in patients with major burns]. Handchir Mikrochir Plast Chir 2001 0.84
43 Preinjury statin use is associated with improved in-hospital survival in elderly trauma patients. J Trauma 2008 0.83
44 The role of statin therapy in sepsis. Ann Pharmacother 2007 0.79
45 Safety of drotrecogin alfa (activated) in severe sepsis: data from adult clinical trials and observational studies. J Crit Care 2009 0.78
46 Relating statin therapy to C-reactive protein levels. Expert Opin Pharmacother 2005 0.78
47 Myoglobinemia after burn injury: relationship to creatine kinase activity in serum. Clin Chem 1986 0.75
48 Effect of lard and corn oil intake on serum lipids in young men. Acta Biol Hung 1989 0.75
49 Long-term neuropsychological sequelae of severe burns. Arch Clin Neuropsychol 1998 0.75
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