A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation

Clinical Trial ID NCT01123122

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993 102.56
2 Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008 47.90
3 Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008 38.76
4 Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000 18.26
5 Five-year follow-up after clinical islet transplantation. Diabetes 2005 7.86
6 Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc 2004 7.03
7 Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996 6.50
8 Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience. Am J Transplant 2005 3.07
9 Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes 1998 2.94
10 Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology 2003 2.76
11 Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function. Diabetes 2001 2.74
12 Loss of beta cell function as fasting glucose increases in the non-diabetic range. Diabetologia 2004 2.72
13 Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest 1991 2.65
14 Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests. J Clin Endocrinol Metab 1976 2.39
15 Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. Diabetes 2001 2.20
16 Insulin secretion in diabetes mellitus. Am J Med 1981 2.05
17 Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 1999 1.94
18 Insulin independence following isolated islet transplantation and single islet infusions. Ann Surg 2003 1.67
19 Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes. J Clin Invest 1995 1.47
20 Edmonton's islet success has indeed been replicated elsewhere. Lancet 2003 1.45
21 Visualization of early engraftment in clinical islet transplantation by positron-emission tomography. N Engl J Med 2007 1.29
22 {beta}-Cell function following human islet transplantation for type 1 diabetes. Diabetes 2005 1.28
23 A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes. Transplantation 2008 1.18
24 Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus. Arch Surg 2005 1.09
25 Acute insulin responses to glucose and arginine as predictors of beta-cell secretory capacity in human islet transplantation. Transplantation 2007 0.99
26 Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15. J Clin Invest 1997 0.98
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