Published in Am J Transplant on August 01, 2005
Islet transplantation a decade later and strategies for filling a half-full glass. Diabetes (2010) 2.07
Primary graft function, metabolic control, and graft survival after islet transplantation. Diabetes Care (2009) 2.06
Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice. Am J Transplant (2007) 1.89
The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects. Transplantation (2008) 1.83
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes. Am J Transplant (2008) 1.68
Long-term insulin independence and improvement in insulin secretion after supplemental islet infusion under exenatide and etanercept. Transplantation (2008) 1.66
Current advances and travails in islet transplantation. Diabetes (2009) 1.63
Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft. Proc Natl Acad Sci U S A (2006) 1.60
Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation. Am J Transplant (2010) 1.48
Update on islet transplantation. Cold Spring Harb Perspect Med (2012) 1.40
A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products. Transplantation (2012) 1.30
Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant (2009) 1.29
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients. Diabetes (2009) 1.27
Pig pancreas anatomy: implications for pancreas procurement, preservation, and islet isolation. Transplantation (2008) 1.27
Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade. Transplantation (2010) 1.23
Point: steady progress and current challenges in clinical islet transplantation. Diabetes Care (2009) 1.20
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocr Rev (2011) 1.10
Current status of islet cell transplantation. J Hepatobiliary Pancreat Surg (2008) 1.07
Donor islet endothelial cells in pancreatic islet revascularization. Diabetes (2011) 1.05
Restoration of hypoglycemia awareness after islet transplantation. Diabetes Care (2008) 1.04
Improved long-term health-related quality of life after islet transplantation. Transplantation (2008) 1.00
Islet transplantation in type 1 diabetes: ongoing challenges, refined procedures, and long-term outcome. Rev Diabet Stud (2012) 0.99
Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes. Transplantation (2008) 0.97
Quadrupole magnetic sorting of porcine islets of Langerhans. Tissue Eng Part C Methods (2009) 0.92
Inflammatory response in islet transplantation. Int J Endocrinol (2014) 0.91
Early metabolic markers of islet allograft dysfunction. Transplantation (2009) 0.91
Standardized transportation of human islets: an islet cell resource center study of more than 2,000 shipments. Cell Transplant (2012) 0.89
Islet cell transplantation. Postgrad Med J (2007) 0.88
Anti-proinflammatory effects of sirolimus on human islet preparations. Transplantation (2008) 0.87
Prolactin supplementation to culture medium improves beta-cell survival. Transplantation (2010) 0.87
Alloreactive (CD4-Independent) CD8+ T cells jeopardize long-term survival of intrahepatic islet allografts. Am J Transplant (2008) 0.87
Characterization of pancreatic ductal cells in human islet preparations. Lab Invest (2008) 0.87
Long-term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine. Transpl Int (2010) 0.87
Pancreatic islet transplantation. World J Gastrointest Surg (2009) 0.86
Improvement of canine islet yield by donor pancreas infusion with a p38MAPK inhibitor. Transplantation (2008) 0.84
Mesenchymal stem cells as feeder cells for pancreatic islet transplants. Rev Diabet Stud (2010) 0.84
Insulin degradation by acinar cell proteases creates a dysfunctional environment for human islets before/after transplantation: benefits of α-1 antitrypsin treatment. Transplantation (2011) 0.84
Islet alone versus islet after kidney transplantation: metabolic outcomes and islet graft survival. Transplantation (2009) 0.83
Antiproinflammatory effects of iodixanol (OptiPrep)-based density gradient purification on human islet preparations. Cell Transplant (2010) 0.82
Comparison of Incubation Solutions Prior to the Purification of Porcine Islet Cells. Cell Med (2013) 0.82
The Choice of Enzyme for Human Pancreas Digestion is a Critical Factor for Increasing the Success of Islet Isolation. Transplant Direct (2015) 0.82
Thrombosis and inflammation in intraportal islet transplantation: a review of pathophysiology and emerging therapeutics. J Diabetes Sci Technol (2008) 0.82
Continuous glucose monitoring system for early detection of graft dysfunction in allogenic islet transplant recipients. Transplant Proc (2006) 0.82
Partial hepatectomy improves the outcome of intraportal islet transplantation by promoting revascularization. Islets (2012) 0.82
Factors affecting transplant outcomes in diabetic nude mice receiving human, porcine, and nonhuman primate islets: analysis of 335 transplantations. Transplantation (2013) 0.82
A Combined Continuous Density/Osmolality Gradient for Supplemental Purification of Human Islets. Cell Med (2012) 0.82
Optimal method for short-term or long-term islet preservation: comparison of islet culture, cold preservation and cryopreservation. J Artif Organs (2014) 0.81
National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes (2016) 0.81
Recent progress in pancreatic islet transplantation. World J Transplant (2011) 0.81
Impact of islet transplantation on glycemic control as evidenced by a continuous glucose monitoring system. J Diabetes Sci Technol (2008) 0.81
Biomolecular surface engineering of pancreatic islets with thrombomodulin. Acta Biomater (2010) 0.81
Lipotoxicity and decreased islet graft survival. Diabetes Care (2009) 0.81
Recent advances in stem cell research for the treatment of diabetes. World J Stem Cells (2009) 0.79
The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: celebrating the legacy of Paul Lacy. Islets (2010) 0.79
Type 2 diabetes mellitus phenotype and graft survival after islet transplantation. Transplantation (2009) 0.79
Regulatory challenges in manufacturing of pancreatic islets. Transplant Proc (2008) 0.78
Evaluation of viable β-cell mass is useful for selecting collagenase for human islet isolation: comparison of collagenase NB1 and liberase HI. Cell Transplant (2011) 0.78
Stable renal function after islet transplantation: importance of patient selection and aggressive clinical management. Transplantation (2009) 0.78
Toward improving human islet isolation from younger donors: rescue purification is efficient for trapped islets. Cell Transplant (2009) 0.78
Glial cell line-derived neurotrophic factor enhances human islet posttransplantation survival. Transplantation (2011) 0.78
Nerve growth factor is associated with islet graft failure following intraportal transplantation. Islets (2011) 0.77
Purification method using iodixanol (OptiPrep)-based density gradient significantly reduces cytokine chemokine production from human islet preparations, leading to prolonged beta-cell survival during pretransplantation culture. Transplant Proc (2009) 0.77
Islet Culture/Preservation Before Islet Transplantation. Cell Med (2015) 0.77
Persufflation (or gaseous oxygen perfusion) as a method of organ preservation. Cryobiology (2012) 0.77
Comprehensive health assessment and five-yr follow-up of allogeneic islet transplant recipients. Clin Transplant (2013) 0.77
Pancreas transplantation. Ann R Coll Surg Engl (2008) 0.76
Use of Mesenchymal Stem Cell-Conditioned Medium to Activate Islets in Preservation Solution. Cell Med (2013) 0.76
Safety and tolerability of the T-cell depletion protocol coupled with anakinra and etanercept for clinical islet cell transplantation. Clin Transplant (2012) 0.76
Mechanisms of hypoglycemia unawareness and implications in diabetic patients. World J Diabetes (2015) 0.76
Pretransplant immune parameters associate with islet allograft outcome: implications for transplant strategy? Diabetes (2009) 0.75
Oxygenation of the Intraportally Transplanted Pancreatic Islet. J Diabetes Res (2016) 0.75
Mesenchymal Stromal Cells as a Therapeutic Strategy to Support Islet Transplantation in Type 1 Diabetes Mellitus. Cell Med (2011) 0.75
The Spleen Is an Ideal Site for Inducing Transplanted Islet Graft Expansion in Mice. PLoS One (2017) 0.75
The Evaluation of Islet Purification Methods That Use Large Bottles to Create a Continuous Density Gradient. Cell Med (2016) 0.75
Effect of exenatide on gastric emptying and graft survival in islet allograft recipients. Transplant Proc (2011) 0.75
Improved human islet preparations using glucocorticoid and exendin-4. Pancreas (2014) 0.75
Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells. Stem Cells Int (2016) 0.75
Hepatic hematoma after islet cell transplantation. Transplantation (2013) 0.75
Regulation of the JNK3 signaling pathway during islet isolation: JNK3 and c-fos as new markers of islet quality for transplantation. PLoS One (2014) 0.75
Pancreas Islet Transplantation for Patients With Type 1 Diabetes Mellitus: A Clinical Evidence Review. Ont Health Technol Assess Ser (2015) 0.75
Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation. Transplant Direct (2015) 0.75
Comparison of Purification Solutions With Different Osmolality for Porcine Islet Purification. Cell Med (2016) 0.75
Binding of the fibronectin-mimetic peptide, PR_b, to alpha5beta1 on pig islet cells increases fibronectin production and facilitates internalization of PR_b functionalized liposomes. Langmuir (2010) 0.75
G-CSF and Exenatide Might Be Associated with Increased Long-Term Survival of Allogeneic Pancreatic Islet Grafts. PLoS One (2016) 0.75
Continuous Quadrupole Magnetic Separation of Islets during Digestion Improves Purified Porcine Islet Viability. J Diabetes Res (2016) 0.75
International trial of the Edmonton protocol for islet transplantation. N Engl J Med (2006) 13.43
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A (2006) 5.41
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature (2005) 3.62
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell (2005) 3.52
Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care (2012) 3.20
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA (2012) 2.85
A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant (2005) 2.74
Innervation patterns of autonomic axons in the human endocrine pancreas. Cell Metab (2011) 2.48
Noninvasive in vivo imaging of pancreatic islet cell biology. Nat Med (2008) 2.41
Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells. Diabetes (2010) 2.36
Rescue purification maximizes the use of human islet preparations for transplantation. Am J Transplant (2005) 2.04
Glutamate is a positive autocrine signal for glucagon release. Cell Metab (2008) 2.01
Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets. Hepatology (2011) 1.94
Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells. Immunity (2002) 1.94
The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects. Transplantation (2008) 1.83
Stopping type 1 diabetes: attempts to prevent or cure type 1 diabetes in man. Diabetes (2011) 1.77
Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates. Diabetes (2010) 1.69
Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes. Diabetes Metab Res Rev (2012) 1.68
Long-term insulin independence and improvement in insulin secretion after supplemental islet infusion under exenatide and etanercept. Transplantation (2008) 1.66
Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med (2011) 1.62
Quantitative differential expression analysis reveals miR-7 as major islet microRNA. Biochem Biophys Res Commun (2007) 1.54
Edmonton's islet success has indeed been replicated elsewhere. Lancet (2003) 1.45
Regulation of alloimmune responses (GvH reactions) in vitro by autologous donor bone marrow cell preparation used in clinical organ transplantation. Transplantation (2002) 1.42
ATP inhibits the generation and function of regulatory T cells through the activation of purinergic P2X receptors. Sci Signal (2011) 1.38
Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device. Transplantation (2006) 1.37
Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol (2005) 1.36
ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell. Proc Natl Acad Sci U S A (2010) 1.35
Improved human islet isolation outcome from marginal donors following addition of oxygenated perfluorocarbon to the cold-storage solution. Transplantation (2003) 1.31
Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant (2009) 1.29
Endocrine cell clustering during human pancreas development. J Histochem Cytochem (2009) 1.26
Toward maximizing the success rates of human islet isolation: influence of donor and isolation factors. Cell Transplant (2007) 1.26
Rapamycin impairs in vivo proliferation of islet beta-cells. Transplantation (2007) 1.26
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells. PLoS One (2008) 1.24
Enhanced oxygenation promotes beta-cell differentiation in vitro. Stem Cells (2007) 1.24
MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas. Gene Expr Patterns (2008) 1.24
Rituximab selectively suppresses specific islet antibodies. Diabetes (2011) 1.23
Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials. Proc Natl Acad Sci U S A (2012) 1.23
High-resolution, noninvasive longitudinal live imaging of immune responses. Proc Natl Acad Sci U S A (2011) 1.22
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling. Proc Natl Acad Sci U S A (2005) 1.22
Point: steady progress and current challenges in clinical islet transplantation. Diabetes Care (2009) 1.20
Combined treatment of intrapancreatic autologous bone marrow stem cells and hyperbaric oxygen in type 2 diabetes mellitus. Cell Transplant (2008) 1.17
Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation. Clin Immunol (2008) 1.14
The use of the BD oxygen biosensor system to assess isolated human islets of langerhans: oxygen consumption as a potential measure of islet potency. Cell Transplant (2006) 1.13
Regional differences in islet distribution in the human pancreas--preferential beta-cell loss in the head region in patients with type 2 diabetes. PLoS One (2013) 1.13
Allosensitization of islet allograft recipients. Transplantation (2007) 1.13
Assessment of cytotoxic lymphocyte gene expression in the peripheral blood of human islet allograft recipients: elevation precedes clinical evidence of rejection. Diabetes (2004) 1.13
Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model. Transplantation (2007) 1.13
Requirements for success in clinical islet transplantation. Transplantation (2005) 1.11
Transplantation: current developments and future directions; the future of clinical islet transplantation as a cure for diabetes. Front Biosci (2008) 1.11