PubRank

A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer

Clinical Trial ID NCT01130142

PubWeight™ 38.83‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01130142

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013 4.78
2 The pancreas cancer microenvironment. Clin Cancer Res 2012 4.10
3 G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov 2011 3.31
4 Unraveling the therapeutic potential of the Hedgehog pathway in cancer. Nat Med 2013 2.55
5 Tackling the cancer stem cells - what challenges do they pose? Nat Rev Drug Discov 2014 2.55
6 Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nat Rev Clin Oncol 2015 2.02
7 The extracellular matrix modulates the hallmarks of cancer. EMBO Rep 2014 1.88
8 Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment. Mol Cancer 2016 1.51
9 Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. J Surg Res 2011 1.31
10 New cast for a new era: preclinical cancer drug development revisited. J Clin Invest 2013 1.11
11 Deciphering the role of stroma in pancreatic cancer. Curr Opin Gastroenterol 2013 1.03
12 Tumor-stromal interactions in pancreatic cancer. Crit Rev Oncog 2013 1.01
13 Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies. Drug Des Devel Ther 2015 0.97
14 Desmoplasia in pancreatic cancer. Can we fight it? Gastroenterol Res Pract 2012 0.96
15 Current and future systemic treatment options in metastatic pancreatic cancer. J Gastrointest Oncol 2014 0.95
16 Novel approaches in the management of pancreatic ductal adenocarcinoma: potential promises for the future. J Hematol Oncol 2015 0.91
17 Carcinogenesis of pancreatic adenocarcinoma: precursor lesions. Int J Mol Sci 2013 0.91
18 From bench to bedside a comprehensive review of pancreatic cancer immunotherapy. J Immunother Cancer 2016 0.90
19 The role of photodynamic therapy in overcoming cancer drug resistance. Photochem Photobiol Sci 2015 0.90
20 Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer. Cancer Growth Metastasis 2015 0.90
21 Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy. Expert Rev Mol Med 2015 0.87
22 Sonic Hedgehog in pancreatic cancer: from bench to bedside, then back to the bench. Surgery 2012 0.83
23 Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy. Expert Opin Ther Targets 2015 0.81
24 A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model. PLoS One 2011 0.78
25 Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies. World J Gastroenterol 2016 0.77
26 Differential role of Hedgehog signaling in human pancreatic (patho-) physiology: An up to date review. World J Gastrointest Pathophysiol 2016 0.75
27 Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma. J Exp Pharmacol 2012 0.75
28 Disrupting the balance between tumor epithelia and stroma is a possible therapeutic approach for pancreatic cancer. Med Sci Monit 2014 0.75
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