Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression.

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Published in J Surg Res on October 08, 2011

Authors

Seth B Krantz1, Mario A Shields, Surabhi Dangi-Garimella, Hidayatullah G Munshi, David J Bentrem

Author Affiliations

1: Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. s-krantz@fsm.northwestern.edu

Associated clinical trials:

A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer | NCT01130142

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas | NCT01088815

Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors | NCT01302405

Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer | NCT01064622

Vismodegib and Gemcitabine Hydrochloride in Treating Patients With Advanced Pancreatic Cancer | NCT01195415

MK0752 and Gemcitabine Hydrochloride in Treating Patients With Stage III and IV Pancreatic Cancer That Cannot Be Removed by Surgery | NCT01098344

A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer | NCT01189929

GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by Surgery | NCT00878163

Hedgehog Inhibition for Pancreatic Ductal Adenocarcinoma (PDAC) in the Preoperative Setting (HIPPoS) (HIPPoS) | NCT01096732

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer | NCT01232829

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors | NCT01131234

Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors | NCT01145456

RO4929097 Before Surgery in Treating Patients With Pancreatic Cancer | NCT01192763

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