PubRank

T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs (Treg)

Clinical Trial ID NCT01210664

PubWeight™ 29.15‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01210664

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 14.33
2 In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 2004 8.00
3 The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A 2007 6.44
4 C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA 2009 4.13
5 CD3-specific antibodies: a portal to the treatment of autoimmunity. Nat Rev Immunol 2007 3.06
6 Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 2008 2.52
7 Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response. Immunity 2013 2.41
8 Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci Transl Med 2015 2.13
9 Regulatory T-cell physiology and application to treat autoimmunity. Immunol Rev 2006 2.13
10 Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection. Nat Med 2002 1.93
11 CD4(+)Foxp3(+) regulatory T cell therapy in transplantation. J Mol Cell Biol 2011 1.45
12 Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of Costimulated autologous T cells. Clin Cancer Res 2009 1.38
13 The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells. Front Immunol 2012 1.23
14 Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers. Immunology 2012 1.20
15 Treating human autoimmunity: current practice and future prospects. Sci Transl Med 2012 1.16
16 T lymphocyte engineering ex vivo for cancer and infectious disease. Expert Opin Biol Ther 2008 1.11
17 Polyclonal anti-T-cell therapy for type 1 diabetes mellitus of recent onset. Rev Diabet Stud 2004 1.08
18 Progress in immune-based therapies for type 1 diabetes. Clin Exp Immunol 2013 1.06
19 Role of autoantibodies in type 1 diabetes. Front Biosci 2007 0.99
20 Stem cell therapy to cure type 1 diabetes: from hype to hope. Stem Cells Transl Med 2013 0.93
21 Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care 2011 0.93
22 T cells in the control of organ-specific autoimmunity. J Clin Invest 2015 0.93
23 Current and future immunomodulation strategies to restore tolerance in autoimmune diseases. Cold Spring Harb Perspect Biol 2012 0.91
24 Translating tolerogenic therapies to the clinic - where do we stand? Front Immunol 2012 0.91
25 Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia. Mol Ther Methods Clin Dev 2014 0.90
26 Regulatory T Cells: Serious Contenders in the Promise for Immunological Tolerance in Transplantation. Front Immunol 2015 0.87
27 Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy. Front Immunol 2015 0.86
28 Inducing and Administering Tregs to Treat Human Disease. Front Immunol 2016 0.84
29 Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol 2013 0.84
30 New and future immunomodulatory therapy in type 1 diabetes. Trends Mol Med 2012 0.83
31 Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biol Blood Marrow Transplant 2013 0.83
32 T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives. Mediators Inflamm 2015 0.82
33 Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region. J Immunol 2014 0.82
34 1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients. PLoS One 2014 0.80
35 Harnessing regulatory T cells for the treatment of inflammatory bowel disease. Inflamm Bowel Dis 2015 0.79
36 PTENtiating autoimmunity through Treg cell deregulation. Nat Immunol 2015 0.79
37 Regulatory T cells control diabetes without compromising acute anti-viral defense. Clin Immunol 2014 0.78
38 Altering the course of type 1 diabetes: an update on prevention and new-onset clinical trials. Pediatr Diabetes 2013 0.77
39 Clinical Efficacy of Stem Cell Therapy for Diabetes Mellitus: A Meta-Analysis. PLoS One 2016 0.77
40 Concise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 Diabetes. Stem Cells 2016 0.76
41 Regulatory T cell therapy for type 1 diabetes: May the force be with you. J Autoimmun 2016 0.76
42 Inducing immune tolerance: a focus on Type 1 diabetes mellitus. Diabetes Manag (Lond) 2013 0.75
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